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Professor Sammut's group is interested in studying and treating the consequences of heart failure, including the cardiovascular effects following hypoxia–ischemia induced brain damage.

He is also investigating the mitochondrial pathophysiology in neurodegeneration and stroke injury, and the neuroprotective effects of pharmacological agents following hypoxia–ischemia induced brain damage.


Find out more about Professor Sammut's research

Publications

Kueh, J. T. B., Stanley, N. J., Hewitt, R. J., Woods, L. M., Larsen, L., Harrison, J. C., … Sammut, I. A., & Larsen, D. S. (2017). Norborn-2-en-7-ones as physiologically-triggered carbon monoxide-releasing prodrugs. Chemical Science, (8), 5454-5459. doi: 10.1039/c7sc01647f

Read, M. I., Harrison, J. C., Kerr, D. S., & Sammut, I. A. (2015). Atenolol offers better protection than clonidine against cardiac injury in kainic acid-induced status epilepticus. British Journal of Pharmacology, 172, 4626-4638. doi: 10.1111/bph.13132

Read, M. I., McCann, D. M., Millen, R. N., Harrison, J. C., Kerr, D. S., & Sammut, I. A. (2015). Progressive development of cardiomyopathy following altered autonomic activity in status epilepticus. American Journal of Physiology: Heart & Circulatory Physiology, 309(9), H1554-H1564. doi: 10.1152/ajpheart.00256.2015

Yao, Y., Fomison-Nurse, I. C., Harrison, J. C., Walker, R. J., Davis, G., & Sammut, I. A. (2014). Chronic bilateral renal denervation attenuates renal injury in a transgenic rat model of diabetic nephropathy. American Journal of Physiology: Renal Physiology, 307, F251-F262. doi: 10.1152/ajprenal.00578.2013

Yao, Y., Davis, G., Harrison, J. C., Walker, R. J., & Sammut, I. A. (2017). Renal functional responses in diabetic nephropathy following chronic bilateral renal denervation. Autonomic Neuroscience, 204, 98-104. doi: 10.1016/j.autneu.2016.09.019

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