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Biochemistry Special Seminar | Thomas Laue, University of New Hampshire, USA

Probing complex molecular interactions at high concentrations

Biomolecular interactions do not take place in dilute, highly‐purified solutions, though that is how we usually characterize them.  Instead, these interactions must take place in highly concentrated, complex mixtures of molecules.  How do these complex, crowded conditions affect the interactions? Are they stronger or weaker? Do sizes of the interacting molecules and their resultant complexes matter? Of equal interest to what forces stabilize the ‘right’ complexes is the reverse problem… how are ‘wrong’ complexes prevented? This talk will cover the processes that govern interactions, and present data that show how these interactions may begin to be characterized using analytical ultracentrifugation. 

Date Monday, 16 October 2017
Time 12:00pm - 1:00pm
Audience Public
Event Category Health Sciences
Event Type Seminar
Departmental Seminar
CampusDunedin
DepartmentBiochemistry
LocationBiochemistry seminar rm 231

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