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Department of Biochemistry profile

Dr Andrew Cridge

PositionResearch Fellow
DepartmentDepartment of Biochemistry
QualificationsBSc(Hons) PhD
Research summaryEvolution and development

Research

My research focuses on environmental physiology, specifically how insects adapt to changes in their environment and coordinate that at a molecular level during embryonic development. Aligned to this I am also interested in how epigenetics can control gene expression through regulating transcription and translation in response to external environmental signals, especially during development. The aim of my research is to develop an understanding of the cellular response to environmental cues and how that affects normal development. I have an additional interest in global change biology and am involved in a longitudinal study to assess the impact of land use on bacterial fauna by determining the loss of biodiversity in bacterial species using metagenomics.

Research Interests:

  • Evolution of insect development
  • Transcription and translation control in growth and differentiation
  • Genome structure organization and its role in gene expression
  • The impact of land use on bacterial biodiversity

Publications

Cridge, A. G., Dearden, P. K., & Brownfield, L. R. (2016). Convergent occurrence of the developmental hourglass in plant and animal embryogenesis? Annals of Botany, 117(5), 833-843. doi: 10.1093/aob/mcw024

Cahyani, I., Cridge, A. G., Engelke, D. R., Ganley, A. R. D., & O'Sullivan, J. M. (2015). A sequence-specific interaction between the Saccharomyces cerevisiae rRNA gene repeats and a locus encoding an RNA polymerase I subunit affects ribosomal DNA stability. Molecular & Cellular Biology, 35(3), 544-554. doi: 10.1128/mcb.01249-14

Cridge, B. J., & Cridge, A. G. (2015). Evaluating how universities engage school students with science: A model based on the analysis of the literature. Australian Universities' Review, 57(1), 34-44.

Sadd, B. M., Barribeau, S. M., Bloch, G., de Graaf, D. C., Dearden, P., Elsik, C. G., … Cridge, A. G., … Duncan, E., … Irvine, F., … Leask, M., Lockett, G. A., … Nair, A., … Blommaert, J., … Worley, K. C. (2015). The genomes of two key bumblebee species with primitive eusocial organization. Genome Biology, 16, 76. doi: 10.1186/s13059-015-0623-3

Cridge, A. G., Leask, M. P., Duncan, E. J., & Dearden, P. K. (2015). What do studies of insect polyphenisms tell us about nutritionally-triggered epigenomic changes and their consequences? Nutrients, 7(3), 1787-1797. doi: 10.3390/nu7031787

Chapter in Book - Research

Osborne, A. J., Duncan, E. J., Cridge, A. G., & Dearden, P. K. (2014). Epigenetics and the maternal germline. In T. Tollefsbol (Ed.), Transgenerational epigenetics: Evidence and debate. (pp. 27-41). London, UK: Academic Press. doi: 10.1016/B978-0-12-405944-3.00004-0

Poole, E. S., Major, L. L., Cridge, A. G., & Tate, W. P. (2004). The mechanism of recoding in pro- and eukaryotes. In K. H. Nierhaus & D. N. Wilson (Eds.), Protein synthesis and ribosome structure: Translating the genome. (pp. 397-428). Weinheim, Germany: Wiley-VCH.

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Journal - Research Article

Cridge, A. G., Dearden, P. K., & Brownfield, L. R. (2016). Convergent occurrence of the developmental hourglass in plant and animal embryogenesis? Annals of Botany, 117(5), 833-843. doi: 10.1093/aob/mcw024

Cahyani, I., Cridge, A. G., Engelke, D. R., Ganley, A. R. D., & O'Sullivan, J. M. (2015). A sequence-specific interaction between the Saccharomyces cerevisiae rRNA gene repeats and a locus encoding an RNA polymerase I subunit affects ribosomal DNA stability. Molecular & Cellular Biology, 35(3), 544-554. doi: 10.1128/mcb.01249-14

Cridge, B. J., & Cridge, A. G. (2015). Evaluating how universities engage school students with science: A model based on the analysis of the literature. Australian Universities' Review, 57(1), 34-44.

Cridge, A. G., Leask, M. P., Duncan, E. J., & Dearden, P. K. (2015). What do studies of insect polyphenisms tell us about nutritionally-triggered epigenomic changes and their consequences? Nutrients, 7(3), 1787-1797. doi: 10.3390/nu7031787

Sadd, B. M., Barribeau, S. M., Bloch, G., de Graaf, D. C., Dearden, P., Elsik, C. G., … Cridge, A. G., … Duncan, E., … Irvine, F., … Leask, M., Lockett, G. A., … Nair, A., … Blommaert, J., … Worley, K. C. (2015). The genomes of two key bumblebee species with primitive eusocial organization. Genome Biology, 16, 76. doi: 10.1186/s13059-015-0623-3

Cridge, A. G., Visweswaraiah, J., Ramesh, R., & Sattlegger, E. (2014). Semi-quantitative colony immunoassay for determining and optimizing protein expression in Saccharomyces cerevisiae and Escherichia coli. Analytical Biochemistry, 447, 82-89. doi: 10.1016/j.ab.2013.10.020

O'Sullivan, J. M., Pai, D. A., Cridge, A. G., Engelke, D. R., & Ganley, A. R. D. (2013). The nucleolus: A raft adrift in the nuclear sea or the keystone in nuclear structure? Biomolecular Concepts, 4(3), 277-286. doi: 10.1515/bmc-2012-0043

Ganegama Arachchi, G. J., Cridge, A. G., Dias-Wanigasekera, B. M., Cruz, C. D., McIntyre, L., Liu, R., … Mutukumira, A. N. (2013). Effectiveness of phages in the decontamination of Listeria monocytogenes adhered to clean stainless steel, stainless steel coated with fish protein, and as a biofilm. Journal of Industrial Microbiology & Biotechnology, 40(10), 1105-1116. doi: 10.1007/s10295-013-1313-3

Bray, B. J., & Cridge, A. G. (2013). Can Education Programmes Effect Long Term Behavioural Change? International Journal of Innovative Interdisciplinary Research, 2(2), 27-33.

Smith, J. M., Cridge, A. G., & Dearden, P. K. (2010). Germ cell specification and ovary structure in the rotifer Brachionus plicatilis. EvoDevo, 1, 5. doi: 10.1186/2041-9139-1-5

Cridge, A. G., Castelli, L. M., Smirnova, J. B., Selley, J. N., Rowe, W., Hubbard, S. J., … Pavitt, G. D. (2010). Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteins. Nucleic Acids Research, 38(22), 8039-8050. doi: 10.1093/nar/gkq686

Cridge, A. G., Major, L. L., Mahagaonkar, A. A., Poole, E. S., Isaksson, L. A., & Tate, W. P. (2006). Comparison of characteristics and function of translation termination signals between and within prokaryotic and eukaryotic organisms. Nucleic Acids Research, 34(7), 1959-1973. doi: 10.1093/nar/gkl074

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