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Profile

Dr Sarah Baird

PositionLecturer
DepartmentDepartment of Pharmacology and Toxicology
QualificationsBSc(Hons) BA PhD
Research summaryCancer research, cell death, adenovirus, oxidative stress

Research

I am researching cell signaling in cell death and the contribution of bone marrow-derived mesenchymal stem cells to tumour stroma development and metastasis.

Publications

Abel, S. D. A., & Baird, S. K. (2017). Honey is cytotoxic towards prostate cancer cells but interacts with the MTT reagent: Considerations for the choice of cell viability assay. Food Chemistry. Advance online publication. doi: 10.1016/j.foodchem.2017.08.083

Badart, M. P., Squires, C. M. L., Baird, S. K., & Hawkins, B. C. (2016). The synthesis of clavatadine C. Tetrahedron Letters, 57(46), 5108-5111. doi: 10.1016/j.tetlet.2016.10.019

Baird, S. K. (2015). Mesenchymal stem cells: How can we realize their therapeutic potential in cancer therapy? Journal of Clinical & Experimental Pathology, 5(1), 206. doi: 10.4172/2161-0681.1000206

Lamb, R. A., Badart, M. P., Swaney, B. E., Gai, S., Baird, S. K., & Hawkins, B. C. (2015). The synthesis and biological evaluation of anithiactin A/thiasporine C and analogues. Australian Journal of Chemistry, 68(12), 1829-1833. doi: 10.1071/CH15461

Clarke, M. R., Imhoff, F. M., & Baird, S. K. (2015). Mesenchymal stem cells inhibit breast cancer cell migration and invasion through secretion of tissue inhibitor of metalloproteinase-1 and -2. Molecular Carcinogenesis, 54(10), 1214-1219. doi: 10.1002/mc.22178

Journal - Research Article

Abel, S. D. A., & Baird, S. K. (2017). Honey is cytotoxic towards prostate cancer cells but interacts with the MTT reagent: Considerations for the choice of cell viability assay. Food Chemistry. Advance online publication. doi: 10.1016/j.foodchem.2017.08.083

Badart, M. P., Squires, C. M. L., Baird, S. K., & Hawkins, B. C. (2016). The synthesis of clavatadine C. Tetrahedron Letters, 57(46), 5108-5111. doi: 10.1016/j.tetlet.2016.10.019

Baird, S. K. (2015). Mesenchymal stem cells: How can we realize their therapeutic potential in cancer therapy? Journal of Clinical & Experimental Pathology, 5(1), 206. doi: 10.4172/2161-0681.1000206

Clarke, M. R., Imhoff, F. M., & Baird, S. K. (2015). Mesenchymal stem cells inhibit breast cancer cell migration and invasion through secretion of tissue inhibitor of metalloproteinase-1 and -2. Molecular Carcinogenesis, 54(10), 1214-1219. doi: 10.1002/mc.22178

Lamb, R. A., Badart, M. P., Swaney, B. E., Gai, S., Baird, S. K., & Hawkins, B. C. (2015). The synthesis and biological evaluation of anithiactin A/thiasporine C and analogues. Australian Journal of Chemistry, 68(12), 1829-1833. doi: 10.1071/CH15461

Baird, S. K., Allan, L., Renner, C., Scott, F. E., & Scott, A. M. (2015). Fibroblast activation protein increases metastatic potential of fibrosarcoma line HT1080 through upregulation of integrin-mediated signaling pathways. Clinical & Experimental Metastasis, 32(5), 507-516. doi: 10.1007/s10585-015-9723-4

Lei, J., Burgess, E. J., Richardson, A. T. B., Hawkins, B. C., Baird, S. K., Smallfield, B. M., van Klink, J. W., & Perry, N. B. (2015). Cytotoxic amides from fruits of kawakawa, Macropiper excelsum. Planta Medica, 81, 1163-1168. doi: 10.1055/s-0035-1546106

Baird, S. K., Rigopoulos, A., Cao, D., Allan, L., Renner, C., Scott, F. E., & Scott, A. M. (2015). Integral membrane protease fibroblast activation protein sensitizes fibrosarcoma to chemotherapy and alters cell death mechanisms. Apoptosis, 20(11), 1483-1498. doi: 10.1007/s10495-015-1166-5

Baird, S. (2014). Mesenchymal stem cells in cancer therapy: Our chance to take charge. European Pharmaceutical Review, 19(2), 55-59.

Ingemarsdotter, C. K., Baird, S. K., Connell, C. M., Öberg, D., Halldén, G., & McNeish, I. A. (2010). Low-dose paclitaxel synergizes with oncolytic adenoviruses via mitotic slippage and apoptosis in ovarian cancer. Oncogene, 29, 6051-6063. doi: 10.1038/onc.2010.335

Vervoort, L., Burvenich, I., Staelens, S., Dumolyn, C., Waegemans, E., Van Steenkiste, M., Baird, S. K., … De Vos, F. (2010). Preclinical evaluation of monoclonal antibody 14C5 for targeting pancreatic cancer. Cancer Biotherapy & Radiopharmaceuticals, 25(2), 193-205. doi: 10.1089/cbr.2009.0696

Firth, C. A., Laing, A. D., Baird, S. K., Pearson, J., & Gieseg, S. P. (2008). Inflammatory sites as a source of plasma neopterin: Measurement of high levels of neopterin and markers of oxidative stress in pus drained from human abscesses. Clinical Biochemistry, 41(13), 1078-1083. doi: 10.1016/j.clinbiochem.2008.06.008

Baird, S. K., Aerts, J. L., Eddaoudi, A., Lockley, M., Lemoine, N. R., & McNeish, I. A. (2008). Oncolytic adenoviral mutants induce a novel mode of programmed cell death in ovarian cancer. Oncogene, 27(22), 3081-3090. doi: 10.1038/sj.onc.1210977

Larsson, D. A., Baird, S., Nyhalah, J. D., Yuan, X.-M., & Li, W. (2006). Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects. Free Radical Biology & Medicine, 41(6), 902-910. doi: 10.1016/j.freeradbiomed.2006.05.032

Leyton, J., Lockley, M., Aerts, J. L., Baird, S. K., Aboagye, E. O., Lemoine, N. R., & McNeish, I. A. (2006). Quantifying the activity of adenoviral E1A CR2 deletion mutants using Renilla luciferase bioluminescence and 3’-deoxy-3’[18F]fluorothymidine positron emission tomography imaging. Cancer Research, 66(18), 9178-9185. doi: 10.1158/0008-5472.CAN-06-1539

Baird, S. K., Kurz, T., & Brunk, U. T. (2006). Metallothionein protects against oxidative stress-induced lysosomal destabilization. Biochemical Journal, 394(Part 1), 275-283. doi: 10.1042/BJ20051143

Baird, S. K., Reid, L., Hampton, M. B., & Gieseg, S. P. (2005). OxLDL induced cell death is inhibited by the macrophage synthesised pterin, 7,8-dihydroneopterin, in U937 cells but not THP-1 cells. Biochimica et Biophysica Acta: Molecular Cell Reserch, 1745, 361-369. doi: 10.1016/j.bbamcr.2005.07.001

Baird, S. K., Hampton, M. B., & Gieseg, S. P. (2004). Oxidized LDL triggers phosphatidylserine exposure in human monocyte cell lines by both caspase-dependent and -independent mechanisms. FEBS Letters, 578, 169-174.

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