Research Professor
Email chris.pemberton@otago.ac.nz
Christchurch Heart Institute
Department of Medicine
University of Otago, Christchurch
PO Box 4345
Christchurch 8140
New Zealand
Current roles
- Director, Translational Biodiscovery Laboratory, Christchurch Heart Institute
- Named Investigator on the current Christchurch Heart Institute HRC Programme grant.
- Principal Investigator on HRC, MBIE and WADA funded signal peptide projects
- Research Professor, Department of Medicine
Research interests
- Novel protein/peptide biomarker identification and measurement
- Cardioendocrine signalling in the circulation and heart tissue
- Ex vivo study of novel cardiovascular diagnostic and therapeutic agents
- Commercialisation of biomedical technologies
Awards and professional memberships
- 2012- Research Commercialisation – Strategic and Implementation Committee, Division of Health Sciences.
- 2012- Corresponding Member, Canterbury, NZ Society of Endocrinology
- 2011 Health Research Council of New Zealand Liley Medal
- 2011- European Society for Cardiology, Working Group on Cellular Biology of the Heart
- 2010- American Association of Clinical Chemistry
- 2007-11 Health Research Council of New Zealand Sir Charles Hercus Fellowship
- 2006-2009 Treasurer, Executive Committee Member, NZ Society of Endocrinology
Publications
Pickering, J. W., Young, J. M., George, P. M., Watson, A. S., Aldous, S. J., Verryt, T., Troughton, R. W., Pemberton, C. J., Richards, A. M., … Than, M. P. (2024). Derivation and validation of thresholds using synthetic data methods for single-test screening of emergency department patients with possible acute myocardial infarction using a point-of-care troponin assay. Journal of Applied Laboratory Medicine. Advance online publication. doi: 10.1093/jalm/jfae001 Journal - Research Article
Appleby, S., Aitken-Buck, H. M., Holdaway, M. S., Byers, M. S., Frampton, C. M., Paton, L. N., Richards, A. M., Lamberts, R. R., & Pemberton, C. J. (2024). Cardiac effects of myoregulin in ischemia-reperfusion. Peptides, 174, 171156. doi: 10.1016/j.peptides.2024.171156 Journal - Research Article
Appleby, S., Frampton, C., Holdaway, M., Chew-Harris, J., Liew, O. W., Chong, J. P. C., Lewis, L., Troughton, R., … Richards, A. M., & Pemberton, C. J. (2023). Circulating erythroferrone has diagnostic utility for acute decompensated heart failure in patients presenting with acute or worsening dyspnea. Frontiers in Cardiovascular Medicine, 10, 1195082. doi: 10.3389/fcvm.2023.1195082 Journal - Research Article
Montecillo, J., Pirker, T., Richards, M., Pemberton, C., & Chew-Harris, J. (2023). Protein glycosylation influences soluble urokinase Plasminogen Activator Receptor (suPAR) measurements. Heart, Lung & Circulation, 32(Suppl. 2), P16. doi: 10.1016/j.hlc.2023.04.237 Conference Contribution - Published proceedings: Abstract
Pirker, T., Keys, T., Pham, T., Montecillo, J., Byers, M., Pemberton, C., Richards, M., & Chew-Harris, J. (2023). Soluble urokinase Plasminogen Activator Receptor (suPAR) promotes cardioprotective intracellular signalling in myocardial ischaemia. Heart, Lung & Circulation, 32(Suppl. 2), O02. doi: 10.1016/j.hlc.2023.04.208 Conference Contribution - Published proceedings: Abstract
Doudesis, D., Lee, K. K., Boeddinghaus, J., Bularga, A., Ferry, A. V., Tuck, C., … Pickering, J. W., Than, M. P., … CoDE-ACS Investigators, including Richards, A. M., Pemberton, C., Troughton, R. W., & Aldous, S. J. (2023). Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations. Nature Medicine, 29, 1201-1210. doi: 10.1038/s41591-023-02325-4 Journal - Research Article
Neumann, J. T., Twerenbold, R., Ojeda, F., Aldous, S. J., Allen, B. R., Apple, F. S., … Pickering, J. W., Pemberton, C. J., … Richards, A. M., … Than, M. P., … Troughton, R. W., … the ARTEMIS study group. (2023). Personalized diagnosis in suspected myocardial infarction. Clinical Research in Cardiology, 112, 1288-1301. doi: 10.1007/s00392-023-02206-3 Journal - Research Article
Koh, H. W. L., Pilbrow, A. P., Tan, S. H., Zhao, Q., Benke, P. I., Burla, B., … Pickering, J. W., Troughton, R., Pemberton, C., … Richards, A. M., & Chan, M. Y. (2023). An integrated signature of extracellular matrix proteins and a diastolic function imaging parameter predicts post-MI long-term outcomes. Frontiers in Cardiovascular Medicine, 10, 1123682. doi: 10.3389/fcvm.2023.1123682 Journal - Research Article
Tan, E. S. J., Chan, S.-P., Choi, Y. C., Pemberton, C. J., Troughton, R., Poppe, K., … Richards, A. M. (2023). Regional handling and prognostic performance of circulating insulin-like growth factor binding protein-7 in heart failure. JACC: Heart Failure, 11(6), 662-674. doi: 10.1016/j.jchf.2023.01.016 Journal - Research Article
Eggers, K. M., Hammarsten, O., Aldous, S. J., Cullen, L., Greenslade, J., Lindahl, B., … Pemberton, C. J., Pickering, J. W., Richards, A. M., Troughton, R. W., & Than, M. P. (2022). Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain. PLoS ONE, 17(11), e0276645. doi: 10.1371/journal.pone.0276645 Journal - Research Article
Pemberton, C. (2022, September). Caterpillars, coronaries and COVID: A career spent testing boundaries. University of Otago, Christchurch, New Zealand. [Inaugural Professorial Lecture]. Other Research Output
Chew-Harris, J., Kuan, W. S., Ibrahim, I., Chan, S. P., Li, Z., Liew, O. W., Appleby, S., Frampton, C., Troughton, R., … Richards, A. M., & Pemberton, C. J. (2022). Comparative performances of soluble urokinase plasminogen activator receptor and Mid-regional proADM to predict composite death and new heart failure rehospitalisation in acutely breathless patients. European Heart Journal, 43(Suppl. 2), (pp. 1087). doi: 10.1093/eurheartj/ehac544.1087 Conference Contribution - Published proceedings: Abstract
Lewis, L. K., Raudsepp, S. D., Whitlow, J. C., Appleby, S., Pemberton, C. J., Yandle, T. G., & Richards, A. M. (2022). Assays specific for BNP1-32 and NT-proBNP exhibit a similar performance to two widely used assays in the diagnosis of heart failure. Clinical Chemistry, 68(10), 1292-1301. doi: 10.1093/clinchem/hvac126 Journal - Research Article
Keys, T., Chew-Harris, J., Pemberton, C., Adamson, P., Troughton, R., Doughty, R., & Richards, A. M. (2022). Soluble urokinase plasminogen activator receptor predicts mortality and adverse cardiovascular outcomes following acute coronary syndrome. Heart, Lung & Circulation, 31(Suppl. 2), (pp. S28-S29). doi: 10.1016/j.hlc.2022.05.020 Conference Contribution - Published proceedings: Abstract
Lee, K. K., Doudesis, D., Anwar, M., Astengo, A., Chenevier-Gobeaux, C., Claessens, Y.-E., … Pemberton, C., … Richards, A. M., … on behalf of the CoDE-HF investigators. (2022). Development and validation of a decision support tool for the diagnosis of acute heart failure: Systematic review, meta-analysis, and modelling study. BMJ, 377, e068424. doi: 10.1136/bmj-2021-068424 Journal - Research Article
Lewis, L., Raudsepp, S., Whitlow, J., Appleby, S., Pemberton, C., & Richards, A. M. (2022). Do more specific assays for B-type natriuretic peptides better predict heart failure in breathless patients than the currently used assays? European Heart Journal, 43(Suppl. 1), (pp. i76). doi: 10.1093/eurheartj/ehab849.060 Conference Contribution - Published proceedings: Abstract
Holdaway, M., Lewis, L., Chew-Harris, J., Richards, M., Pemberton, C., & Appleby, S. (2021). Erythroferrone can diagnose acute decompensated heart failure in patients presenting with breathlessness. Heart, Lung & Circulation, 30(Suppl. 2), (pp. S76). doi: 10.1016/j.hlc.2021.05.044 Conference Contribution - Published proceedings: Abstract
Chew-Harris, J., Appleby, S., Adamson, P., Troughton, R., Richards, A. M., & Pemberton, C. (2021). Soluble urokinase plasminogen activator receptor (suPAR) predicts 2-year cardiovascular events in patients after acute chest pain. Heart, Lung & Circulation, 30(Suppl. 2), (pp. S85-S86). doi: 10.1016/j.hlc.2021.05.070 Conference Contribution - Published proceedings: Abstract
Chew-Harris, J., Appleby, S., Adamson, P., Troughton, R., Richards, A. M., & Pemberton, C. (2021). Prognostic performance of soluble urokinase plasminogen activator receptor (suPAR) in predicting mortality in Asian and Western patients with acute breathlessness. Heart, Lung & Circulation, 30(Suppl. 2), (pp. S86). doi: 10.1016/j.hlc.2021.05.070 Conference Contribution - Published proceedings: Abstract
Chew-Harris, J., Appleby, S., Adamson, P., Troughton, R., Richards, A. M., & Pemberton, C. (2021). Soluble urokinase plasminogen activator receptor (suPAR) predicts mortality in patients with acute chest pain. Heart, Lung & Circulation, 30(Suppl. 2), (pp. S86). doi: 10.1016/j.hlc.2021.05.069 Conference Contribution - Published proceedings: Abstract
Richards, A. M., & Pemberton, C. J. (2021). Progress in proteomic probing for pathogenic pathways in heart failure with preserved ejection fraction. European Journal of Heart Failure, 23, 1645-1647. doi: 10.1002/ejhf.2332 Journal - Research Other
Palmer, B. R., Paterson, M. A., Frampton, C. M., Pilbrow, A. P., Skelton, L., Pemberton, C. J., … Troughton, R. W., Richards, A. M., & Cameron, V. A. (2021). Vascular endothelial growth factor-A promoter polymorphisms, circulating VEGF-A and survival in acute coronary syndromes. PLoS ONE, 16(7), e0254206. doi: 10.1371/journal.pone.0254206 Journal - Research Article
Richards, A. M., & Pemberton, C. J. (2021). Urinary peptides in heart failure: The need for care with pees and cues. European Journal of Heart Failure, 23, 1888-1890. doi: 10.1002/ejhf.2269 Journal - Research Other
Lassé, M., Pilbrow, A. P., Kleffmann, T., Andersson Överström, E., von Zychlinski, A., Frampton, C. M. A., … Troughton, R. W., Lewis, L. K., Prickett, T. C. R., Pemberton, C. J., Richards, A. M., & Cameron, V. A. (2021). Fibrinogen and hemoglobin predict near future cardiovascular events in asymptomatic individuals. Scientific Reports, 11(1), 4605. doi: 10.1038/s41598-021-84046-7 Journal - Research Article
Poh, K. K., Shabbir, A., Ngiam, J. N., Lee, P. S. S., So, J., Frampton, C. M., Pemberton, C. J., & Richards, A. M. (2021). Plasma clearance of B-type natriuretic peptide (BNP) before and after bariatric durgery for morbid obesity. Clinical Chemistry, 67(4), 662-671. doi: 10.1093/clinchem/hvaa308 Journal - Research Article
Chew-Harris, J., Appleby, S., Troughton, R. W., Richards, A. M., & Pemberton, C. J. (2020). Soluble urokinase plasminogen activator receptor (suPAR) can predict long-term mortality in patients with acute chest pain. European Heart Journal, 41(Suppl. 2), (pp. 1695). doi: 10.1093/ehjci/ehaa946.1695 Conference Contribution - Published proceedings: Abstract
Chew-Harris, J., Appleby, S., Kuan, W. S., Ibrahim, I., Chan, S. P., Li, Z., … Frampton, C., Troughton, R. W., … Richards, A. M., & Pemberton, C. J. (2020). Prognostic performance of soluble urokinase plasminogen activator receptor for 1-year mortality in Asian and Western patients with acute breathlessness. European Heart Journal, 41(Suppl. 2), (pp. 1202). doi: 10.1093/ehjci/ehaa946.1202 Conference Contribution - Published proceedings: Abstract
Chew-Harris, J., Appleby, S., Troughton, R. W., Richards, A. M., & Pemberton, C. J. (2020). Soluble urokinase plasminogen activator receptor (suPAR) predicts 2-year cardiovascular events in patients after acute chest pain. European Heart Journal, 41(Suppl. 2), (pp. 1696). doi: 10.1093/ehjci/ehaa946.1696 Conference Contribution - Published proceedings: Abstract
Chan, M. Y., Efthymios, M., Tan, S. H., Pickering, J. W., Troughton, R., Pemberton, C., … Pilbrow, A., & Richards, A. M. (2020). Prioritizing candidates of post-myocardial infarction heart failure using plasma proteomics and single-cell transcriptomics. Circulation, 142, 1408-1421. doi: 10.1161/circulationaha.119.045158 Journal - Research Article
Lewis, L. K., Raudsepp, S. D., Prickett, T. C. R., Yandle, T. G., Pemberton, C. J., & Richards, A. M. (2020). ProBNP processing is decreased by obesity in patients with heart failure. Annals of Translational Medicine, 8(4), 135. doi: 10.21037/atm.2019.12.81 Journal - Research Other
Harris, S. L., Troughton, R., Lewis, L., Austin, N., & Pemberton, C. (2020). Circulating forms of B-type natriuretic peptide in very preterm infants. Journal of Applied Laboratory Medicine, 5(3), 506-515. doi: 10.1093/jalm/jfaa003 Journal - Research Article
Pickering, J. W., Young, J. M., George, P. M., Pemberton, C. J., Watson, A., Aldous, S. J., … Troughton, R. W., Richards, A. M., … Than, M. P. (2020). Early kinetic profiles of troponin I and T measured by high-sensitivity assays in patients with myocardial infarction. Clinica Chimica Acta, 505, 15-25. doi: 10.1016/j.cca.2020.02.009 Journal - Research Article
Appleby, S., Chew-Harris, J., Troughton, R. W., Richards, A. M., & Pemberton, C. J. (2020). Analytical and biological assessment of circulating human erythroferrone. Clinical Biochemistry, 79, 41-47. doi: 10.1016/j.clinbiochem.2020.02.001 Journal - Research Article
Lewis, L., Raudsepp, S. D., Yandle, T. G., Frampton, C. M., Richards, A. M., Prickett, T. C. R., … Pemberton, C. J. (2020). ProBNP glycosylation of threonine 71 is increased with obesity in patients with heart failure. European Heart Journal, 41(Suppl. 1), ehz872.007. doi: 10.1093/ehjci/ehz872.007 Conference Contribution - Published proceedings: Abstract
Kuan, W. S., Ibrahim, I., Chan, S. P., Li, Z., Liew, O. W., Frampton, C., Troughton, R., Pemberton, C. J., … Richards, A. M. (2020). Mid-regional pro-adrenomedullin outperforms N-terminal pro-B-type natriuretic peptide for the diagnosis of acute heart failure in the presence of atrial fibrillation. European Journal of Heart Failure, 22, 692-700. doi: 10.1002/ejhf.1660 Journal - Research Article
Mbikou, P., Rademaker, M. T., Charles, C. J., Richards, M. A., & Pemberton, C. J. (2020). Cardiovascular effects of DWORF (dwarf open reading frame) peptide in normal and ischaemia/reperfused isolated rat hearts. Peptides, 124, 170192. doi: 10.1016/j.peptides.2019.170192 Journal - Research Article
Pemberton, C. J., Lee, J. A., Aldous, S., Appleby, S., Chew-Harris, J., Than, M., Troughton, R. W., & Richards, A. M. (2019). The signal peptide of CNP is a novel predictor of MI, MACE and bleeding risk in chest pain patients. European Heart Journal, 40(Suppl. 1), (pp. 2029). doi: 10.1093/eurheartj/ehz745.0283 Conference Contribution - Published proceedings: Abstract
Chew-Harris, J. S., Appleby, S., Richards, A. M., Troughton, R. W., & Pemberton, C. J. (2019). Soluble urokinase plasminogen activator receptor (suPAR) predicts 1 year mortality in patients with acute breathlessness. European Heart Journal, 40(Suppl. 1), (pp. 1573). doi: 10.1093/eurheartj/ehz748.0939 Conference Contribution - Published proceedings: Abstract
Pemberton, C. J., Lee, J. A., Aldous, S., Skelton, L., Frampton, C. M., Than, M., Troughton, R. W., Adamson, P., & Richards, A. M. (2019). The protein APRIL predicts adverse outcomes in DAPT patients better than NT-proBNP and troponin. European Heart Journal, 40(Suppl. 1), (pp. 1052). doi: 10.1093/eurheartj/ehz748.0509 Conference Contribution - Published proceedings: Abstract
Aldous, S., Pickering, J., Young, J., George, P., Watson, A., Troughton, R., Pemberton, C., Richards, M., … Than, M. (2019). Rapid rule-out of myocardial infarction with a novel high precision point-of-care troponin assay appears safe and effective. European Heart Journal, 40(Suppl. 1), (pp. 1626). doi: 10.1093/eurheartj/ehz748.0992 Conference Contribution - Published proceedings: Abstract
Adamson, P. D., McAllister, D., Pilbrow, A., Pickering, J. W., Poppe, K., Shah, A., Whalley, G., … Pemberton, C., Troughton, R. W., … Richards, A. M. (2019). Convalescent troponin and cardiovascular death following acute coronary syndrome. Heart, 105, 1717-1724. doi: 10.1136/heartjnl-2019-315084 Journal - Research Article
Chew-Harris, J., Appleby, S., Richards, A. M., Troughton, R. W., & Pemberton, C. J. (2019). Analytical, biochemical and clearance considerations of soluble urokinase plasminogen activator receptor (suPAR) in healthy individuals. Clinical Biochemistry, 69, 36-44. doi: 10.1016/j.clinbiochem.2019.05.010 Journal - Research Article
Lewis, L. K., Raudsepp, S. D., Prickett, T. C. R., Yandle, T. G., Doughty, R. N., Frampton, C. M., Pemberton, C. J., & Richards, A. M. (2019). ProBNP that is not glycosylated at threonine 71 is decreased with obesity in patients with heart failure. Clinical Chemistry, 65(9), 1115-1124. doi: 10.1373/clinchem.2019.302547 Journal - Research Article
Richards, A. M., Pemberton, C., & Yandle, T. (2019). How does neprilysin inhibition in heart failure work? European Journal of Heart Failure, 21(5), 606-608. doi: 10.1002/ejhf.1454 Journal - Research Other
Chew-Harris, J., Appleby, S., Troughton, R., Richards, M., & Pemberton, C. (2018). Soluble urokinase plasminogen activator receptor is a strong prognostic indicator of mortality in acutely breathless patients. Circulation, 138(Suppl. 1), A11125. [Abstract] Conference Contribution - Published proceedings: Abstract
Appleby, S., Chew-Harris, J., Troughton, R., Richards, M., & Pemberton, C. (2018). Erythroferrone can diagnose acute decompensated heart failure in patients presenting with breathlessness. Circulation, 138(Suppl. 1), A11094. [Abstract] Conference Contribution - Published proceedings: Abstract
Mbikou, P. P., Pemberton, C. J., Charles, C. J., & Rademaker, M. T. (2018, August). Characterising the role and the therapeutic potential of novel peptide DWORF in heart disease. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Chew-Harris, J., Appleby, S., Troughton, R., Richards, M., & Pemberton, C. (2018, August). Soluble urokinase plasminogen activator receptor is a strong prognostic indicator of mortality in acutely breathless patients. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Pickering, J. W., Young, J. M., George, P. M., Watson, A. S., Aldous, S. J., Troughton, R. W., Pemberton, C. J., Richards, A. M., … Than, M. P. (2018). Validity of a novel point-of-care troponin assay for single-test rule-out of acute myocardial infarction. JAMA Cardiology, 3(11), 1108-1112. doi: 10.1001/jamacardio.2018.3368 Journal - Research Article
Pemberton, C. J., Lee, J. A., Jardine, R., Skelton, L., Frampton, C. M., Troughton, R. W., Richards, A. M., on behalf of Christchurch Heart Institute. (2018). The TNF receptor TACI is a novel inflammatory predictor of heart failure. European Heart Journal, 39(Suppl. 1), (pp. 576-577). doi: 10.1093/eurheartj/ehy565.P2791 Conference Contribution - Published proceedings: Abstract
Nanayakkara, S., Pemberton, C., Patel, H., Vizi, D., Mak, V., Richards, A. M., … Kaye, D. M. (2018). Mid regional atrial natriuretic peptide is an independent predictor of peak pulmonary capillary wedge pressure in patients with heart failure with preserved ejection fraction. European Heart Journal, 39(Suppl. 1), (pp. 222). doi: 10.1093/eurheartj/ehy565.1096 Conference Contribution - Published proceedings: Abstract
Marks, E. C. A., Wilkinson, T. M., Frampton, C. M., Skelton, L., Pilbrow, A. P., Yandle, T. G., Pemberton, C. J., … Whalley, G. A., … Troughton, R. W., … Cameron, V. A., Richards, A. M., Gieseg, S. P., & Palmer, B. R. (2018). Plasma levels of soluble VEGF receptor isoforms, circulating pterins and VEGF system SNPs as prognostic biomarkers in patients with acute coronary syndromes. BMC Cardiovascular Disorders, 18, 169. doi: 10.1186/s12872-018-0894-1 Journal - Research Article
Than, M. P., Aldous, S. J., Troughton, R. W., Pemberton, C. J., Richards, A. M., Frampton, C. M. A., Florkowski, C. M., George, P. M., … Young, J. M., … Pickering, J. W. (2018). Detectable high-sensitivity cardiac troponin within the population reference interval conveys high 5-year cardiovascular risk: An observational study. Clinical Chemistry, 64(7), 1044-1053. doi: 10.1373/clinchem.2017.285700 Journal - Research Article
van der Linden, N., Wildi, K., Twerenbold, R., Pickering, J. W., Than, M., Cullen, L., … Richards, A. M., Troughton, R., Pemberton, C., … Mueller, C. (2018). Combining high sensitivity cardiac troponin I and cardiac troponin T in the early diagnosis of acute myocardial infarction. Circulation, 138(10), 989-999. doi: 10.1161/circulationaha.117.032003 Journal - Research Article
Harris, S. L., More, K., Dixon, B., Troughton, R., Pemberton, C., Horwood, J., Ellis, N., & Austin, N. (2018). Factors affecting N-terminal pro-B-type natriuretic peptide levels in preterm infants and use in determination of haemodynamic significance of patent ductus arteriosus. European Journal of Pediatrics, 177(4), 521-532. doi: 10.1007/s00431-018-3089-y Journal - Research Article
Arrigo, M., Vodovar, N., Nougué, H., Sadoune, M., Pemberton, C. J., Ballan, P., … Mebazaa, A. (2018). The heart regulates the endocrine response to heart failure: Cardiac contribution to circulating neprilysin. European Heart Journal, 39(20), 1794-1798. doi: 10.1093/eurheartj/ehx679 Journal - Research Article
Pickering, J. W., Flaws, D., Smith, S. W., Greenslade, J., Cullen, L., Parsonage, W., … Richards, A. M., Troughton, R., Pemberton, C., George, P. M., & Than, M. P. (2018). A risk assessment score and initial high-sensitivity troponin combine to identify low risk of acute myocardial infarction in the emergency department. Academic Emergency Medicine, 25(4), 434-443. doi: 10.1111/acem.13343 Journal - Research Article
Pemberton, C. J., Richards, A. M., Nicholls, M. G., & Yandle, T. G. (2017). Biomarkers. [Marker reference: INSDx] (9,630,985). United States. Intellectual Property
Pilbrow, A. P., Runesson, A. S. D., Sommer, M. A. W., Jones, G. T., Frampton, C. M., Pemberton, C. J., Troughton, R. W., Richards, A. M., & Cameron, V. A. (2017, September). Using microRNAs to predict heart disease events in the general population. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Aitken-Buck, H. M., Appleby, S., Pemberton, C. J., & Lamberts, R. R. (2017, September). Myoregulin has no effect on contraction or relaxation of isolated rat hearts. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Laribi, S., Pemberton, C. J., Kirwan, L., Nouira, S., Turkdogan, K., Yilmaz, M. B., Troughton, R. W., … Richards, M., … on behalf of the GREAT (Global Research on Acute Conditions Team) Network. (2017). Mortality and acute exacerbation of COPD: A pilot study on the influence of myocardial injury. European Respiratory Journal, 49(6), 1700096. doi: 10.1183/13993003.00096-2017 Journal - Research Other
Pickering, J. W., Than, M. P., Cullen, L., Aldous, S., ter Avest, E., Body, R., … Florkowski, C. M., … George, P., … Pemberton, C., Richards, A. M., … Troughton, R., … Young, J. (2017). Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac troponin T measurement below the limit of detection: A collaborative meta-analysis. Annals of Internal Medicine, 166(10), 715-724. doi: 10.7326/m16-2562 Journal - Research Article
Pemberton, C. (2017). Prognostic outcomes in patients with heart failure: A new SuPAR biomarker for risk prediction? JACC: Heart Failure, 5(4), 278-279. doi: 10.1016/j.jchf.2017.02.009 Journal - Research Other
Pemberton, C. J., Charles, C. J., & Richards, A. M. (2017). Cardiac natriuretic peptides. In J. C. Schisler, C. H. Lang & M. S. Willis (Eds.), Endocrinology of the heart in health and disease. (pp. 3-39). Elsevier. doi: 10.1016/B978-0-12-803111-7.00001-4 Chapter in Book - Research
Liebetrau, C., Gaede, L., Wolter, J. S., Homann, J., Meyer, A., Dörr, O., … Richards, A. M., & Pemberton, C. J. (2017). Release kinetics of high-sensitivity cardiac troponins I and T and troponin T upstream open reading frame peptide (TnTuORF) in clinically induced acute myocardial infarction. Biomarkers, 22(3-4), 304-310. doi: 10.1080/1354750X.2016.1252965 Journal - Research Article
Ibrihim, I., Kuan, W. S., Frampton, C., Troughton, R., Liew, O. W., Chong, J. P. C., … Pemberton, C. J., … Richards, A. M. (2017). Superior performance of N-terminal pro brain natriuretic peptide for diagnosis of acute decompensated heart failure in an Asian compared with a Western setting. European Journal of Heart Failure, 19(2), 209-217. doi: 10.1002/ejhf.612 Journal - Research Article
Pemberton, C. J., Richards, A. M., Charles, C. J., & Siriwardena, M. (2016). Cardiovascular therapeutics. [Marker reference: BNPTx] (2012 8 0050843.1). China. Intellectual Property
Mbikou, P., Byers, M., Charles, C. J., Rademaker, M. T., & Pemberton, C. J. (2016, August-September). Role of B-type natriuretic signal peptide on AKT and ERK1/2 activity in myocardial rat ischemia. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Mbikou, P., Byers, M., Charles, C. J., Rademaker, M. T., & Pemberton, C. J. (2016, August). Role of B-type natriuretic signal peptide on AKT and ERK1/2 activity in myocardial rat ischemia. Poster session presented at the Medical Sciences Congress (MedSci), Nelson, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Pemberton, C. J., Frampton, C. M., Aldous, S., Bailey, M., Young, J., Troughton, R., Than, M., & Richards, M. (2016). B-type natriuretic peptide signal peptide (BNPsp) in patients presenting with chest pain. Clinical Biochemistry, 49, 645-650. doi: 10.1016/j.clinbiochem.2016.02.015 Journal - Research Article
Cullen, L., Greenslade, J. H., Menzies, L., Leong, A., Than, M., Pemberton, C., Aldous, S., Pickering, J., … Parsonage, W. A. (2016). Time to presentation and 12-month health outcomes in patients presenting to the emergency department with symptoms of possible acute coronary syndrome. Emergency Medicine Journal, 33, 390-395. doi: 10.1136/emermed-2015-204978 Journal - Research Article
Pemberton, C. J., Lee, J., Than, M., Pickering, J. W., Troughton, R. W., & Richards, M. (2015). Can copeptin assist the diagnosis of acute kidney injury in breathless patients? European Heart Journal, 36(Suppl. 1), (pp. 800). doi: 10.1093/eurheartj/ehv400 Conference Contribution - Published proceedings: Abstract
Liebetrau, C., Doerr, O. D., Gaede, L. G., Berkowitsch, A. B., Troidl, C. T., Hamm, C. H., … Richards, A. M., & Pemberton, C. J. (2015). Release kinetics of B-type natriuretic peptide signal peptide (BNPsp) in patients with acute myocardial infarction. European Heart Journal, 36(Suppl. 1), (pp. 71). doi: 10.1093/eurheartj/ehv398 Conference Contribution - Published proceedings: Abstract
Lee, J., Than, M., Aldous, S., Troughton, R., Richards, M., & Pemberton, C. J. (2015). CNP signal peptide in patients with cardiovascular disease. Frontiers in Cardiovascular Medicine, 2, 28. doi: 10.3389/fcvm.2015.00028 Journal - Research Article
Liebetrau, C., Gaede, L., Dörr, O., Blumenstein, J., Rosenburg, S., Hoffmann, J., … Richards, A. M., & Pemberton, C. J. (2015). Reference values and release kinetics of B-type natriuretic peptide signal peptide in patients with acute myocardial infarction. Clinical Chemistry, 61(12), 1532-1539. doi: 10.1373/clinchem.2015.244327 Journal - Research Article
Menzies, L., Cullen, L., Greenslade, J., Leong, A., Than, M., Pemberton, C., Aldous, S., Pickering, J., … Parsonage, W. (2015). The association of delay in presentation and 12-month health outcomes in emergency patients with symptoms of possible acute coronary syndromes. Heart, Lung & Circulation, 24(Suppl. 3), (pp. S167-S168). doi: 10.1016/j.hlc.2015.06.134 Conference Contribution - Published proceedings: Abstract
Fitzsimons, S., Troughton, R., Gamble, G., Pemberton, C., Devlin, G., Lund, M., Richards, M., & Doughty, R. (2015). High prevalence of iron deficiency in heart failure with preserved ejection fraction. Heart, Lung & Circulation, 24(Suppl. 2), (pp. S78). doi: 10.1016/j.hlc.2015.04.070 Conference Contribution - Published proceedings: Abstract
Arshad, M., Richards, M., Pemberton, C., & Troughton, R. (2015). Routine measurement of NT-proBNP and post-discharge clinical outcomes: Initial findings from a randomised controlled trial. Heart, Lung & Circulation, 24(Suppl. 2), (pp. S94). doi: 10.1016/j.hlc.2015.04.109 Conference Contribution - Published proceedings: Abstract
Lee, J., Young, J., Frampton, C. M., Aldous, S., Troughton, R. W., Than, M., Richards, A. M., & Pemberton, C. J. (2015). A novel troponin T peptide in humans: Assay, biochemistry and preliminary findings in acute coronary syndromes. International Journal of Cardiology, 190, 68-74. doi: 10.1016/j.ijcard.2015.04.145 Journal - Research Article
Meller, B., Cullen, L., Parsonage, W. A., Greenslade, J. H., Aldous, S., Reichlin, T., … Troughton, R., Pemberton, C. J., Richards, A. M., … Than, M., & Mueller, C. (2015). Accelerated diagnostic protocol using high-sensitivity cardiac troponin T in acute chest pain patients. International Journal of Cardiology, 184C, 208-215. doi: 10.1016/j.ijcard.2015.02.006 Journal - Research Article
Pemberton, C. (2014, November). Hunting the Snark: New peptides to measure in the circulation. Verbal presentation at the HeartOtago First Australasian Symposium: Bench to Bedside and Back: New Advances in Cardiovascular Research, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Pemberton, C. J. (2014). Signal peptides: New markers in cardiovascular disease? Biomarkers in Medicine, 8(8), 1013-1019. doi: 10.2217/bmm.14.64 Journal - Research Article
Pemberton, C. J., Siriwardena, M., Kleffmann, T., & Richards, A. M. (2014). C-type natriuretic peptide (CNP) signal peptide fragments are present in the human circulation. Biochemical & Biophysical Research Communications, 449, 301-306. doi: 10.1016/j.bbrc.2014.05.020 Journal - Research Article
Mahagamasekera, P. G., Ruygrok, P. N., Palmer, S. C., Richards, A. M., Ansell, G. S., Nicholls, M. G., Pemberton, C. J., Lewis, L. K., & Yandle, T. G. (2014). B-type natriuretic peptide forms within the heart, coronary sinus, and peripheral circulation in humans: Evidence for degradation before secretion. Clinical Chemistry, 60(3), 549-558. doi: 10.1373/clinchem.2013.210435 Journal - Research Article
Cullen, L., Aldous, S., Than, M., Greenslade, J. H., Tate, J. R., George, P. M., … Richards, A. M., Ungerer, J. P. J., Troughton, R. W., … Pemberton, C. J., Florkowski, C., … Parsonage, W. A. (2014). Comparison of high sensitivity troponin T and I assays in the diagnosis of non-ST elevation acute myocardial infarction in emergency patients with chest pain. Clinical Biochemistry, 47(6), 321-326. doi: 10.1016/j.clinbiochem.2013.11.019 Journal - Research Article
Pemberton, C. J., Richards, A. M., Nicholls, M. G., & Yandle, T. G. (2013). Biomarkers. [Marker reference: GHRDx] (8,507,209). United States. Intellectual Property
Pemberton, C., Chase, G., & Willmott, G. (2013, June). Collaborating for Success: Point of care diagnostics. Verbal presentation at the Healthcare Congress: Future of Healthcare in New Zealand, Auckland, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Cullen, L., Parsonage, W., Greenslade, J., Aldous, S., George, P., Lamanna, A., … Richards, M., Pemberton, C. J., Than, M., on behalf of the Emergency Cardiology Group. (2013). Diagnostic accuracy of highly sensitive troponin I versus highly sensitive troponin T assays for acute myocardial infarction within two hours of emergency department presentation. European Heart Journal, 34(Suppl. 1), (pp. 86). doi: 10.1093/eurheartj/eht307.P484 Conference Contribution - Published proceedings: Abstract
Richards, M., Troughton, R., Espiner, E., Cameron, V., Ellmers, L., Pilbrow, A., Charles, C., Rademaker, M., Pemberton, C., & Yandle, T. (2013). Christchurch Heart Institute. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 68-74). Christchurch, New Zealand: University of Otago. Chapter in Book - Other
Byers, M. S., Bailey, M., Siriwardena, M., Lewis, L. K., Oliver, J., Troughton, R., Richards, A. M., & Pemberton, C. J. (2013, August). Plasma ghrelin signal peptide can exclude co-existent pneumonia in acute decompensated heart failure. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Pemberton, C. J., Aldous, S., Bailey, M., Young, J., Troughton, R., Than, M., & Richards, M. (2013, August). BNP signal peptide in the diagnosis of acute coronary syndromes. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Pemberton, C. J., & Kleffmann, T. (2013). Circulating signal peptides: More than just a bus ticket? Cardiovascular Endocrinology, 2(3), 41-45. doi: 10.1097/XCE.0b013e328362e44e Journal - Research Article
Siriwardena, M., Charles, C. J., Byers, M., Richards, A. M., & Pemberton, C. J. (2013). BNP signal peptide is protective in ischaemia reperfusion injury. Heart, Lung & Circulation, 22(7), (pp. 578-579). doi: 10.1016/j.hlc.2013.04.074 Conference Contribution - Published proceedings: Abstract
Greenslade, J. H., Cullen, L., Than, M., Aldous, S., Chu, K., Brown, A. F. T., Richards, A. M., Pemberton, C. J., George, P., & Parsonage, W. A. (2013). Validation of the Vancouver Chest Pain Rule using troponin as the only biomarker: A prospective cohort study. American Journal of Emergency Medicine, 31(7), 1103-1107. doi: 10.1016/j.ajem.2013.04.016 Journal - Research Article
Cullen, L., Mueller, C., Parsonage, W. A., Wildi, K., Greenslade, J. H., Twerenbold, R., Aldous, S., … Troughton, R., … George, P., … Pemberton, C. J., Richards, A. M., … Florkowski, C., Deely, J. M., & Than, M. (2013). Validation of high-sensitivity troponin I in a 2-hour diagnostic strategy to assess 30-day outcomes in emergency department patients with possible acute coronary syndrome. JACC, 62(14), 1242-1249. doi: 10.1016/j.jacc.2013.02.078 Journal - Research Article
Greenslade, J. H., Cullen, L., Kalinowski, L., Parsonage, W., Palmer, S., Aldous, S., Richards, M., … Troughton, R., Pemberton, C., & Than, M. (2013). Examining renal impairment as a risk factor for acute coronary syndrome: A prospective observational study. Annals of Emergency Medicine, 62(1), 38-46. doi: 10.1016/j.annemergmed.2013.01.011 Journal - Research Article
Pemberton, C. J., Richards, A. M., Nicholls, M. G., & Yandle, T. G. (2012). Methods of diagnosing acute cardiac disorders using BNP-SP. [Marker reference: BNPDx] (8,289,772). United States. Intellectual Property
Pemberton, C. (2012). Existing and new BNP peptides. New Zealand Journal of Medical Laboratory Science, 66(3), (pp. 93). [Abstract] Conference Contribution - Published proceedings: Abstract
Aldous, S., Pemberton, C., Richards, A. M., Troughton, R., & Than, M. (2012). High-sensitivity troponin T for early rule-out of myocardial infarction in recent onset chest pain. Emergency Medicine Journal, 29(10), 805-810. doi: 10.1136/emermed-2011-200222 Journal - Research Article
Siriwardena, M., Campbell, V., Richards, A. M., & Pemberton, C. J. (2012). Cardiac biomarker responses to dobutamine stress echocardiography in healthy volunteers and patients with coronary artery disease. Clinical Chemistry, 58(10), 1492-1494. doi: 10.1373/clinchem.2012.187682 Journal - Research Other
Aldous, S., Pemberton, C., Richards, A. M., Troughton, R., & Than, M. (2012). Authors' response. Emergency Medicine Journal, 29(7), 601-602. doi: 10.1136/emermed-2012-201216 Journal - Professional & Other Non-Research Articles
Pemberton, C. (2012). Endogenous peptides as therapeutic agents: Some new candidates. Proceedings of the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives. Retrieved from http://bioactives.otago.ac.nz/ Conference Contribution - Published proceedings: Abstract
Pemberton, C. (2012, February). Endogenous peptides as therapeutic agents: Some new candidates. Invited presentation at the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Pemberton, C. J. (2012). Signal peptides: Time to leave the ER behind? Proceedings of the Medical Sciences Congress (MedSci). (pp. 38). Retrieved from http://www.medscinz.co.nz/QRW2012%20MedSci%20Abstracts.pdf Conference Contribution - Published proceedings: Abstract
Byers, M. S., Siriwardena, M., Ruygrok, P., Yandle, T., Kleffmann, T., Richards, A. M., & Pemberton, C. J. (2012). Ghrelin signal peptide (GHRSP): Identification, immunoassay and circulating profile. Proceedings of the Medical Sciences Congress (MedSci). (pp. 18). Retrieved from http://www.medscinz.co.nz/QRW2012%20MedSci%20Abstracts.pdf Conference Contribution - Published proceedings: Abstract
Pemberton, C. J. (2012, August). Signal peptides: Time to leave the ER behind? Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Pemberton, C. J., Siriwardena, M., Kleffmann, T., Ruygrok, P., Palmer, S. C., Yandle, T. G., & Richards, A. M. (2012). First identification of circulating Prepro-A-Type natriuretic peptide (PreproANP) signal peptide fragments in humans: Initial assessment as cardiovascular biomarkers. Clinical Chemistry, 58(4), 757-767. doi: 10.1373/clinchem.2011.176990 Journal - Research Article
Aldous, S., Pemberton, C., Troughton, R., Than, M., & Richards, A. M. (2012). Heart fatty acid binding protein and myoglobin do not improve early rule out of acute myocardial infarction when highly sensitive troponin assays are used. Resuscitation, 83(2), e27-e28. doi: 10.1016/j.resuscitation.2011.09.031 Journal - Research Other
Charles, C. J., Espiner, E. A., Nicholls, M. G., Pemberton, C. J., Troughton, R. W., Yandle, T. G., & Richards, A. M. (2011, September). Cardiac biomarkers: Clinical utility for diagnosis, prognosis and guiding treatment of cardiovascular disease. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Pemberton, C. (2011, March). Biomarkers: Searching for a new signal. Verbal presentation at the NZBIO Conference: Enabling Successful Bio Enterprise, Auckland, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Pemberton, C. J., Richards, A. M., Siriwardena, M., Cameron, V. A., Yandle, T. G., Nicholls, M. G., Kleffmann, T., & Ruygrok, P. (2011). [Response to letter regarding article, B-Type natriuretic peptide signal peptide circulates in human blood: Evaluation as a potential biomarker of cardiac ischemia]. Circulation, 123(6), e234. doi: 10.1161/CIRCULATIONAHA.110.003574 Journal - Research Other
Troughton, R. W., Lewis, L. K., Yandle, T. G., Pemberton, C. J., & Nicholls, M. G. (2011). B-type natriuretic peptides: Looking to the future. Annals of Medicine, 43(3), 188-197. doi: 10.3109/07853890.2010.526630 Journal - Research Article
Kleffmann, T., Siriwardena, M., Ruygrok, P., Cameron, V. A., Yandle, T. G., Nicholls, M. G., Richards, A. M., & Pemberton, C. J. (2010). Characterisation of unusual modifications of the circulating signal peptide of B-type naturetic peptide: A potential biomarker of cardiac ischemia. Proceedings of the 9th Human Proteome World Congress (HUPO): Launch of the Human Proteome Project. (pp. 106). Retrieved from http://www.hupo.org/congress/congress_2010/downloads/HUPO2010%20World%20Congress%20Abstract%20Book.pdf Conference Contribution - Published proceedings: Abstract
Yandle, T. G., Mahagamasekera, P. M. G., Ruygrok, P., Palmer, S. C., Ansell, G., Nicholls, G., Pemberton, C. J., & Richards, M. (2010). Cardiac tissue, coronary sinus and circulating forms of B-type natriuretic peptide in in patients with and without heart failure. Endocrine Journal. 57(Suppl. 2), (pp. S325). [Abstract] Conference Contribution - Published proceedings: Abstract
Siriwardena, M., Kleffmann, T., Ruygrok, P., Cameron, V. A., Yandle, T. G., Nicholls, M. G., Richards, A. M., & Pemberton, C. J. (2010). B-type natriuretic peptide signal peptide circulates in human blood. Evaluation as a potential biomarker of cardiac ischemia. Circulation, 122, 255-264. doi: 10.1161/CIRCULATIONAHA.109.909937 Journal - Research Article
Prosser, H. C., Richards, A. M., Forster, M. E., & Pemberton, C. J. (2010). Regional vascular response to ProAngiotensin-12 (PA12) through the rat arterial system. Peptides, 31, 1540-1545. doi: 10.1016/j.peptides.2010.05.009 Journal - Research Article
Doogue, M. P., Begg, E. J., Moore, M. P., Lunt, H., Pemberton, C. J., & Zhang, M. (2009). Metformin increases plasma ghrelin in Type 2 diabetes. British Journal of Clinical Pharmacology, 68(6), 875-882. doi: 10.1111/j.1365-2125.2009.03372.x Journal - Research Article
Prosser, H. C. G., Forster, M. E., Richards, A. M., & Pemberton, C. J. (2009). Cardiac chymase converts rat proAngiotensin-12 (PA12) to angiotensin II: Effects of PA12 upon cardiac haemodynamics. Cardiovascular Research, 82(1), 40-50. doi: 10.1093/cvr/cvp003 Journal - Research Article
Prosser, H. C. G., Forster, M. E., Richards, A. M., & Pemberton, C. J. (2008, November). Cardiac chymase activity converts proangiotensin-12 (PA12) to angiotensin II: Effects of PA12 upon cardiac haemodynamics. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Piuhola, J., Kerkelä, R., Keenan, J. I., Hampton, M. B., Richards, A. M., & Pemberton, C. (2008, November). Direct cardiac actions of erythropoietin (EPO): Effects on cardiac contractility, BNP secretion and ischemia-reperfusion injury. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Pemberton, C. (2008, October). Biomarkers: Searching for a signal. Verbal presentation at the New Zealand-Singapore Heart Failure Research Symposium, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Mahagamasekera, M. G. P., Ruygrok, P. N., Palmer, S., Ansell, G., Nicholls, M. G., Pemberton, C. J., Richards, A. M., & Yandle, T. G. (2008, November). B-type natriuretic peptide and its degradation products in the heart and circulation in end-stage heart failure. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Siriwardena, M., Nicholls, M. G., Yandle, T. G., Frampton, C. M., Richards, A. M., & Pemberton, C. J. (2008). Immunoreactive BNP-signal peptide: A potential early biomarker of AMI. Heart, Lung & Circulation, 17(Suppl. 3), (pp. S104). doi: 10.1016/j.hlc.2008.05.250 Conference Contribution - Published proceedings: Abstract
Pemberton, C. J., Rothwell, S. E., & Richards, A. M. (2008). The novel adipocytokine resistin worsens cardiac ischaemia-reperfusion injury. European Heart Journal. 29(Suppl. 1), (pp. 629). [Abstract] Conference Contribution - Published proceedings: Abstract
Prosser, H. C. G., Forster, M. E., Richards, A. M., & Pemberton, C. J. (2008). Urotensin II and urotensin II-related peptide (URP) in cardiac ischemia-reperfusion injury. Peptides, 29(5), 770-777. doi: 10.1016/j.peptides.2007.08.013 Journal - Research Article
Pemberton, C. J., & Richards, A. M. (2008). Biochemistry of ghrelin precursor peptides. Vitamins & Hormones, 77, 13-30. doi: 10.1016/S0083-6729(06)77002-9 Journal - Research Article
Piuhola, J., Kerkelä, R., Keenan, J. I., Hampton, M. B., Richards, A. M., & Pemberton, C. J. (2008). Direct cardiac actions of erythropoietin (EPO): Effects on cardiac contractility, BNP secretion and ischaemia/reperfusion injury. Clinical Science, 114(4), 293-304. doi: 10.1042/CS20070229 Journal - Research Article
Pemberton, C. J. (2008). Leptin-induced cardiac hypertrophy: RhoAing a lipid raft down a protective p38 MAPK signalling stream? [Editorial]. Cardiovascular Research, 77(1), 4-5. doi: 10.1093/cvr/cvm053 Journal - Research Other
Prosser, H. C. G., Forster, M. E., Richards, A. M., & Pemberton, C. J. (2007). Direct effects of proangiotensin-12 on the isolated rat heart. European Heart Journal. 28(Abstract Suppl.), (pp. 365). [Abstract] Conference Contribution - Published proceedings: Abstract
Pemberton, C. J. (2007). Hypertension, cardiotrophin-1 and gp130: Three points to heart failure? [Editorial comment]. Journal of Hypertension, 25(10), 2008-2010. doi: 10.1097/HJH.0b013e3282ef5632 Journal - Research Other
Davis, M. E., Pemberton, C. J., Yandle, T. G., Fisher, S. F., Lainchbury, J. G., Frampton, C. M., Rademaker, M. T., & Richards, A. M. (2007). Urocortin 2 infusion in healthy humans: Hemodynamic, neurohormonal, and renal responses. JACC, 49(4), 461-471. Journal - Research Article
Davis, M. E., Pemberton, C. J., Yandle, T. G., Fisher, S. F., Lainchbury, J. G., Frampton, C. M., Rademaker, M. T., & Richards, M. (2007). Urocortin 2 infusion in human heart failure. European Heart Journal, 28(21), 2589-2597. Journal - Research Article
Bang, A. S., Soule, S. G., Yandle, T. G., Richards, A. M., & Pemberton, C. J. (2007). Characterisation of proghrelin peptides in mammalian tissue and plasma. Journal of Endocrinology, 192, 313-323. Journal - Research Article
Davis, M. E., Pemberton, C. J., Yandle, T. G., Fisher, S. F., Lainchbury, J. G., Frampton, C. M., Rademaker, M. T., Richards, A. M., on behalf of Christchurch Cardioendocrine Research Group. (2006). Urocortin 2 infusion in humans with mild heart failure: Haemodynamics, neurohormonal and renal responses. European Heart Journal, 27(Suppl. 1), (pp. 488). [Abstract] Conference Contribution - Published proceedings: Abstract
Davis, M. E., Pemberton, C. J., Yandle, T. G., Lainchbury, J. G., Frampton, C. M., Rademaker, M. T., & Richards, M. (2006). Urocortin 2 infusion in healthy humans induces marked hemodynamic, neurohormonal, and renal responses. Journal of the American College of Cardiology. 47(4, Suppl. A), (pp. 310A). [Abstract] Conference Contribution - Published proceedings: Abstract
Prosser, H. C. G., Leprince, J., Vaudry, H., Richards, A. M., Forster, M. E., & Pemberton, C. J. (2006). Cardiovascular effects of native and non-native urotensin II and urotensin II-related peptide on rat and salmon hearts. Peptides, 27, 3261-3268. Journal - Research Article
Rothwell, S. E., Richards, A. M., & Pemberton, C. J. (2006). Resistin worsens cardiac ischaemia-reperfusion injury. Biochemical & Biophysical Research Communications, 349, 400-407. Journal - Research Article
Doogue, M. P., Begg, E. J., Moore, M. P., Lunt, H., Zhang, M., & Pemberton, C. (2005). Metformin pharmacokinetics and the effect on hormones involved in appetite regulation. Proceedings of the Joint Meeting of ASCEPT and APSA. ASCEPT: Melbourne, Australia. [Abstract] Conference Contribution - Published proceedings: Abstract
Pemberton, C., Raudsepp, S. D., Cameron, V. A., Yandle, T. G., & Richards, A. M. (2005). Cardiotrophin-1: A complex cytokine stimulated by ventricular stretch. European Heart Journal, 26(Suppl. 1), (pp. 66). doi: 10.1093/eurheartj/26.suppl_1.1 Conference Contribution - Published proceedings: Abstract
Davis, M. E., Skinner, M. H., Pemberton, C. J., Yandle, T. G., Lainchbury, J. G., Rademaker, M. T., Frampton, C. M., & Richards, A. M. (2005). First report of urocortin 2 infusion in normal humans. Heart, Lung & Circulation, 14(1, Suppl.), (pp. S111-S112). doi: 10.1016/j.hlc.2005.04.007 Conference Contribution - Published proceedings: Abstract
Pemberton, C. J., Raudsepp, S. D., Yandle, T. G., Cameron, V. A., & Richards, A. M. (2005). Plasma cardiotrophin-1 is elevated in human hypertension and stimulated by ventricular stretch. Cardiovascular Research, 68(1), 109-117. Journal - Research Article
Davis, M. E., Pemberton, C. J., Yandle, T. G., Lainchbury, J. G., Rademaker, M. T., Nicholls, M. G., Frampton, C. M., & Richards, A. M. (2005). Effect of urocortin I infusion in humans with stable congestive cardiac failure. Clinical Science, 109(4), 381-388. doi: 10.1042/CS20050079 Journal - Research Article
Soule, S., Pemberton, C., Hunt, P., Cole, D., Raudsepp, S., & Inder, W. (2005). Prandial regulation of ghrelin secretion in humans: Does glucagon contribute to the preprandial increase in circulating ghrelin? Clinical Endocrinology, 63(4), 412-417. doi: 10.1111/j.1365-2265.2005.02357.x Journal - Research Article
Rothwell, S. E., Pemberton, C. J., & Richards, A. M. (2004, November). Resistin: A link between metabolic syndrome and cardiovascular disease. Verbal presentation at the Medical Sciences Congress: Physiological Society of New Zealand, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Pemberton, C. J., Raudsepp, S., Yandle, T. G., & Richards, A. M. (2004). Cardiotrophin-1: Circulating levels, cardiac secretion and molecular forms in cardiovascular disease. New Zealand Medical Sciences Congress AGM. [Abstract] Conference Contribution - Published proceedings: Abstract
Pemberton, C. J., Tokola, H., Bagi, Z., Koller, A., Pöntinen, J., Ola, A., … Ruskoaho, H. (2004). Ghrelin induces vasoconstriction in the rat coronary vasculature without altering cardiac peptide secretion. American Journal of Physiology: Heart & Circulatory Physiology, 287, H1522-H1529. Journal - Research Article
Piuhola, J., Pemberton, C., Hampton, M., & Richards, M. (2004, June). Multiple cardiac effects of erythropoietin. Poster session presented at the 14th European Meeting on Hypertension, Paris. Conference Contribution - Poster Presentation (not in published proceedings)
Pemberton, C. J., Rothwell, S. E., Yandle, T. G., & Richards, A. M. (2004). Ghrelin and resistin: Metabolic hormones influencing cardiac function. First Annual Canterbury Health Research Scientific Conference. (pp. 31). [Abstract] Conference Contribution - Published proceedings: Abstract
Davis, M. E., Pemberton, C. J., Yandle, T. G., Lainchbury, J. G., Rademaker, M. T., Nicholls, M. G., Frampton, C. M., & Richards, A. M. (2004). Urocortin infusion in humans with stable congestive cardiac failure. Heart, Lung & Circulation, 13(Suppl. 2), (pp. S117-S118). doi: 10.1016/j.hlc.2004.05.001 Conference Contribution - Published proceedings: Abstract
Davis, M. E., Pemberton, C. J., Yandle, T. G., Lainchbury, J. G., Rademaker, M. T., Nicholls, M. G., Frampton, C. M., & Richards, A. M. (2004). Urocortin-1 infusion in normal humans. Journal of Clinical Endocrinology & Metabolism, 89(3), 1402-1409. Journal - Research Article
Davis, M., Pemberton, C. J., Yandle, T. G., Lainchbury, J. G., Rademaker, M. T., Nicholls, M. G., Frampton, C. M., & Richards, A. M. (2003, November). First report of urocortin infusion and actions in normal humans. Verbal presentation at the American Heart Association Conference 2003, Orlando, USA. Conference Contribution - Verbal presentation and other Conference outputs
Davis, M., Pemberton, C. J., Yandle, T. G., Lainchbury, J. G., Rademaker, M. T., Nicholls, M. G., Frampton, C. M., & Richards, A. M. (2003, July). First report of urocortin infusion and actions in normal humans. Verbal presentation at the Christchurch Medical Research Conference 2003, Christchurch, NZ. Conference Contribution - Verbal presentation and other Conference outputs
Davis, M., Pemberton, C. J., Yandle, T. G., Lainchbury, J. G., Rademaker, M. T., Nicholls, M. G., Frampton, C. M., & Richards, A. M. (2003). First report of urocortin infusion and actions in normal humans. Circulation, 108(17 Suppl. IV), (pp. 242). [Abstract] Conference Contribution - Published proceedings: Abstract
Pemberton, C. J., Wimalasena, P., Yandle, T. G., Soule, S. G., & Richards, A. M. (2003). C-terminal pro-ghrelin peptides are present in the human circulation. Biochemical & Biophysical Research Communications, 310(2), 567-573. Journal - Research Article
Pemberton, C. J., Tokola, H., Pontinen, J., Ola, A., Vuolteenaho, O., & Ruskoaho, H. (2002). Ghrelin has a coronary vasoconstrictor action: role of L-Type Ca2+ channels and PK-C. The Endocrine Society of Australia, Proceedings 2002. 45, (pp. 165). Adelaide, Australia: Endocrine Society of Australia. [Full Paper] Conference Contribution - Published proceedings: Full paper
Pemberton, C. J., Yandle, T. G., & Espiner, E. A. (2002). Immunoreactive forms of natriuretic peptides in ovine brain: Response to heart failure. Peptides, 23(12), 2235-2244. Journal - Research Article
Rademaker, M. T., Charles, C. J., Cooper, G. J. S., Coy, D. H., Espiner, E. A., Lewis, L. K., Nicholls, M. G., Pemberton, C. J., & Richards, A. M. (2000, October). Combined adrenomedullin administration and neutral endopeptidase inhibitor in heart failure. Verbal presentation at the 4th Annual Meeting of the Society for Cardiovascular Endocrinology and Metabolism, Australia. Conference Contribution - Verbal presentation and other Conference outputs
Rademaker, M. T., Cameron, V. A., Charles, C. J., Espiner, E. A., Nicholls, M. G., Pemberton, C. J., & Richards, A. M. (2000). Neurohormones in an ovine model of compensated post-infarction left ventricular dysfunction. American Journal of Physiology: Heart & Circulatory Physiology, 278, H731-H740. Journal - Research Article
Pemberton, C. J., Johnson, M. L., Yandle, T. G., & Espiner, E. A. (2000). Deconvolution analysis of cardiac natriuretic peptides during acute volume overload. Hypertension, 36(3), 355-359. Journal - Research Article
Pemberton, C. J., Johnson, M., Yandle, T. G., & Espiner, E. A. (1999). The in vivo Half-life of NT-ProBNP is 14-fold Longer Than Mature BNP in Ovine Plasma. In A. Zanchetti & G. Mancia (Eds.), Ninth European Meeting on Hypertension - Abstracts. 9, (pp. S55-S56). Hagerstown, United States of America: International Society of Hypertension. [Full Paper] Conference Contribution - Published proceedings: Full paper
Seidler, T., Pemberton, C. J., Yandle, T. G., Espiner, E. A., Nicholls, M. G., & Richards, A. M. (1999). The amino terminal regions of proBNP and proANP: Oligomerise through leucine zipper-like coiled-coil motifs. Biochemical & Biophysical Research Communications, 255, 495-501. Journal - Research Article
Pemberton, C. J., Yandle, T. G., Rademaker, M. T., Charles, C. J., Aitken, G. D., & Espiner, E. A. (1998). Amino-terminal proBNP in ovine plasma: evidence for enhanced secretion in response to cardiac overload. American Journal of Physiology: Heart & Circulatory Physiology, 275(4Pt2), H1200-H1208. Journal - Research Article
Pemberton, C. J., Yandle, T. G., Rademaker, M. T., Charles, C. J., Aitken, G. D., & Espiner, E. A. (1997). The Amino Terminal Fragment of ProBNP Circulates In Ovine Plasma. Proceedings of the Endocrine Society of Australia. 40, (pp. 48). Melbourne, Australia: The Endocrine Society of Australia. [Abstract] Conference Contribution - Published proceedings: Abstract
Pemberton, C. J., Yandle, T. G., Charles, C. J., Rademaker, M. T., Aitken, G. D., & Espiner, E. A. (1997). Ovine brain natriuretic peptide in cardiac tissues and plasma: effects of cardiac hypertrophy and heart failure on tissue concentration and molecular forms. Journal of Endocrinology, 155(3), 541-550. Journal - Research Article
Charles, C. J., Kaaja, R. J., Espiner, E. A., Nicholls, M. G., Pemberton, C. J., Richards, A. M., & Yandle, T. G. (1996). Natriuretic peptides in sheep with pressure overload left venticular hypertrophy. Clinical & Experimental Hypertension, 18(8), 1051-1071. Journal - Research Article