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Professor John Evans

John Evans

Research Professor

MSc PhD

Tel 64 3 364 1698

Email john.evans@otago.ac.nz

Professor John Evans is studying gynaecological cancers in collaboration with Peter Sykes. These investigations aim to understand cancers and develop new treatments.

Another set of studies investigates the regulation of the ovulatory cycle. This research is aimed at developing methods of fertility modulation.

Previous investigations of the peptides in cells lining blood vessels have provided new information on vascular disease.

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Publications

Murray, L. M., Nock, V., Evans, J. J., & Alkaisi, M. M. (2016). The use of substrate materials and topography to modify growth patterns and rates of differentiation of muscle cells. Journal of Biomedical Materials Research Part A, 104A, 1638-1645. doi: 10.1002/jbm.a.35696

Tan, L. H., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2015). The characteristics of Ishikawa endometrial cancer cells are modified by substrate topography with cell-like features and the polymer surface. International Journal of Nanomedicine, 10, 4883-4895. doi: 10.2147/ijn.s86336

Mutreja, I., Woodfield, T. B. F., Sperling, S., Nock, V., Evans, J. J., & Alkaisi, M. M. (2015). Positive and negative bioimprinted polymeric substrates: New platforms for cell culture. Biofabrication, 7, 025002. doi: 10.1088/1758-5090/7/2/025002

Hogg, S. J., Evans, J. J., Sykes, P. H., & Chitcholtan, K. (2015). A method to investigate the anti-metabolic activity of anti-cancer agents on ovarian cancer cells cultured in a 96-well high throughput format. Journal of Ovarian Research, 8, 43. doi: 10.1186/s13048-015-0172-0

Mutreja, I., Evans, J. J., & Alkaisi, M. M. (2015, February). Positive and negative signatures of C2C12 cells replicated in polymer matrix control muscle cell response. Verbal presentation at the Seventh International Conference on Advanced Materials & Nanotechnology (AMN-7), Nelson, New Zealand.

Journal - Research Article

Murray, L. M., Nock, V., Evans, J. J., & Alkaisi, M. M. (2016). The use of substrate materials and topography to modify growth patterns and rates of differentiation of muscle cells. Journal of Biomedical Materials Research Part A, 104A, 1638-1645. doi: 10.1002/jbm.a.35696

Tan, L. H., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2015). The characteristics of Ishikawa endometrial cancer cells are modified by substrate topography with cell-like features and the polymer surface. International Journal of Nanomedicine, 10, 4883-4895. doi: 10.2147/ijn.s86336

Hogg, S. J., Evans, J. J., Sykes, P. H., & Chitcholtan, K. (2015). A method to investigate the anti-metabolic activity of anti-cancer agents on ovarian cancer cells cultured in a 96-well high throughput format. Journal of Ovarian Research, 8, 43. doi: 10.1186/s13048-015-0172-0

Mutreja, I., Woodfield, T. B. F., Sperling, S., Nock, V., Evans, J. J., & Alkaisi, M. M. (2015). Positive and negative bioimprinted polymeric substrates: New platforms for cell culture. Biofabrication, 7, 025002. doi: 10.1088/1758-5090/7/2/025002

Murray, L. M., Nock, V., Evans, J. J., & Alkaisi, M. M. (2014). Bioimprinted polymer platforms for cell culture using soft lithography. Journal of Nanobiotechnology, 12, 60. doi: 10.1186/s12951-014-0060-6

Evans, G. E., Martínez-Conejero, J. A., Phillipson, G. T. M., Sykes, P. H., Sin, I. L., Lam, E. Y. N., … Evans, J. J. (2014). In the secretory endometria of women, luminal epithelia exhibit gene and protein expressions that differ from those of glandular epithelia. Fertility & Sterility, 102(1), 307-317. doi: 10.1016/j.fertnstert.2014.04.005

Yoshida, A., Chitcholtan, K., Evans, J. J., Uemura, S., & Beasley, S. W. (2014). Provision of optimal conditions for in vitro differentiation into peristaltic smooth muscle from a murine induced pluripotent stem cell line. JSM Regenerative Medicine & Bioengineering, 2(1), 1011.

Chitcholtan, K., Asselin, E., Parent, S., Sykes, P. H., & Evans, J. J. (2013). Differences in growth properties of endometrial cancer in three dimensional (3D) culture and 2D cell monolayer. Experimental Cell Research, 319(1), 75-87. doi: 10.1016/j.yexcr.2012.09.012

Evans, J. J., Wilkinson, T. M., & Wall, D. J. N. (2013). A two-pathway mathematical model of the LH response to GnRH that predicts self-priming. International Journal of Endocrinology, 2013, 410348. doi: 10.1155/2013/410348

Ibrahim, S. N., Murray, L., Nock, V., Evans, J. J., & Alkaisi, M. M. (2012). The quadrupole microelectrode design on a multilayer biochip for dielectrophoretic trapping of single cells. Microelectronic Engineering, 97, 369-374. doi: 10.1016/j.mee.2012.04.018

Evans, J. J., Chitcholtan, K., Dann, J. M., Guilford, P., Harris, G., Lewis, L. K., Nagase, J., … Sykes, P. H. (2012). Adrenomedullin interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades. Gynecologic Oncology, 125(1), 214-219. doi: 10.1016/j.ygyno.2011.12.429

Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2012). The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer. Journal of Translational Medicine, 10(1), 38-53. doi: 10.1186/1479-5876-10-38

Yoshida, A., Chitcholtan, K., Evans, J. J., Nock, V., & Beasley, S. W. (2012). In vitro tissue engineering of smooth muscle sheets with peristalsis using a murine induced pluripotent stem cell line. Journal of Pediatric Surgery, 47(2), 329-335. doi: 10.1016/j.jpedsurg.2011.11.027

Evans, G. E., Phillipson, G. T. M., Sin, I. L., Frampton, C. M. A., Kirker, J. A., Bigby, S. M., & Evans, J. J. (2012). Gene expression confirms a potentially receptive endometrium identified by histology in fertile women. Human Reproduction, 27(9), 2747-2755. doi: 10.1093/humrep/des233

Ibrahim, S. N., Murray, L., Evans, J. J., & Alkaisi, M. M. (2012). Trapping single cells: Comparison between sandwiched insulation with back contact (SIBC) and planar biochip. Materials Science Forum, 700, 188-194. doi: 10.4028/www.scientific.net/MSF.700.188

Evans, G. E., Martínez-Conejero, J. A., Phillipson, G. T. M., Simón, C., McNoe, L. A., Sykes, P. H., … Evans, J. J. (2012). Gene and protein expression signature of endometrial glandular and stromal compartments during the window of implantation. Fertility & Sterility, 97(6), 1365-1373. doi: 10.1016/j.fertnstert.2012.03.007

Evans, J. J., & Anderson, G. M. (2012). Balancing ovulation and anovulation: Integration of the reproductive and energy balance axes by neuropeptides. Human Reproduction Update, 18(3), 313-332. doi: 10.1093/humupd/dms004

Nock, V., Murray, L., Samsuri, F., Alkaisi, M. M., & Evans, J. J. (2011). Microfluidic arrays for bioimprint of cancer cells. Microelectronic Engineering, 88(8), 1828-1831. doi: 10.1016/j.mee.2010.12.042

Samsuri, F., Alkaisi, M. M., Evans, J. J., Chitcholtan, K., & Mitchell, J. S. (2011). Detection of changes in cell membrane structures using the Bioimprint technique. Microelectronic Engineering, 88(8), 1871-1874. doi: 10.1016/j.mee.2010.12.069

Evans, J. J., & Chitcholtan, K. (2011). Extracellular matrix proteins in the anterior pituitary gland. Open Neuroendocrinology Journal, 4, 111-119. doi: 10.2174/1876528901104010111

Samsuri, F., Alkaisi, M. M., Mitchell, J. S., & Evans, J. J. (2010). Replication of cancer cells using soft lithography bioimprint technique. Microelectronic Engineering, 87, 699-703. doi: 10.1016/j.mee.2009.12.068

Nock, V., Murray, L., Samsuri, F., Alkaisi, M. M., & Evans, J. J. (2010). Microfluidics-assisted photo nanoimprint lithography for the formation of cellular bioimprints. Journal of Vacuum Science & Technology B: Microelectronics & Nanometer Structures, 28(6), C6K17-C6K22. doi: 10.1116/1.3501342

Samsuri, F., Mitchell, J. S., Alkaisi, M. M., & Evans, J. J. (2009). Replication of muscle cell using bioimprint. AIP Conference Proceedings, 1151, 71-74. doi: 10.1063/1.3203250

Dann, J. M., Sykes, P. H., Mason, D. R., & Evans, J. J. (2009). Regulation of Vascular Endothelial Growth Factor in endometrial tumour cells by resveratrol and EGCG. Gynecologic Oncology, 113(3), 374-378.

Peters, E. E. M., Towler, K. L., Mason, D. R., & Evans, J. J. (2009). Effects of galanin and leptin on gonadotropin-releasing hormone-stimulated luteinizing hormone release from the pituitary. Neuroendocrinology, 89(1), 18-26.

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