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Associate Professor Tim Woodfield

Tim Woodfield

Research Associate Professor

Rutherford Discovery Fellow 2012-2017

BE Mech Hons (Canterbury), MASc (Toronto), PhD (Twente)

Email tim.woodfield@otago.ac.nz 

Tel 64 3 378 6114
Fax 64 3 364 0909

Roles

  • Principal Investigator, Christchurch Regenerative Medicine and Tissue Engineering (CReaTE) Group
  • Theme Leader, Regenerative Medicine – University of Otago Centre for Bioengineering & Nanomedicine
  • Adjunct Assoc Professor, Institute of Health & Biomedical Innovation (IHBI), Queensland University of Technology, Brisbane, Australia
  • Adjunct Snr Fellow, Dept of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand
  • Principal Investigator, Centre of Research Excellence in Medical Technologies
  • Assoc Investigator, MacDiarmid Institute for Advanced Materials & Nanotechnology
  • Assoc Investigator, Maurice Wilkins Centre for Molecular Diversity

Professional Affiliations

Professional Interests

Orthopaedic Tissue Engineering and Regenerative Medicine

  • Stem cell and scaffold-based regeneration of cartilage and bone
  • Bio-fabrication and advanced scaffold design
  • Orthopaedic medical device development

Christchurch Regenerative Medicine and Tissue Engineering (CReATE) Group website
Regenerative Medicine website - Centre for Bioengineering & Nanomedicine

Top 10 Publications

  1. T. Nguyen, M. Staiger, G. Dias, T. Woodfield (2011). A Novel Manufacturing Route for Fabrication of Topologically-Ordered Porous Magnesium Scaffolds. Advanced Engineering Materials. 13(9): p872-881. IF: 1.738.
  2. Woodfield T, Guggenheim M, von Rechenberg B, Riesle J, van Blitterswijk CA, Wedler V. (2009). Rapid prototyping of anatomically shaped, tissue-engineered implants for restoring congruent articulating surfaces in small joints. Cell Proliferation. 42(4): p485-497. IF: 3.120
  3. Woodfield T., Moroni L., Malda J. (2009) Combinatorial approaches to controlling cell behaviour and tissue formation in 3D via rapid-prototyping and smart scaffold design. Combinatorial Chemistry & High Throughput Screening. 12(6); p562-579. IF: 2.573
  4. Woodfield T., Miot S., Martin I., van Blitterswijk C.A., Riesle J. (2006). The Regulation of Expanded Human Nasal Chondrocyte Re-differentiation Capacity by Substrate Composition and Gas Plasma Surface Modification. Biomaterials. 27(7). IF: 7.882
  5. Habibovic P., Woodfield T., de Groot K., van Blitterswijk C. (2006). Predictive value of in vitro and in vivo assays in bone and cartilage repair - What do they really tell us about the clinical performance? Advances in Experimental Medicine & Biology, 585: 327-360. IF: 1.379
  6. Woodfield T., de Wijn J., Sims T., Hollander A., van Blitterswijk C.A., Riesle J. (2005). Polymer Scaffolds Fabricated with Organised Pore-size Gradients as a Model for Studying Zonal Organisation within Tissue Engineered Cartilage Constructs. Tissue Engineering. 11(9-10). IF: 4.699
  7. Woodfield T.[1], Miot S.1, Daniels A.U., Suetterlin R., Peterschmitt I., Heberer M., van Blitterswijk CA., Riesle J., Martin I. (2005). Effects of Scaffold Composition and Architecture on Human Nasal Chondrocyte Re-differentiation and Cartilagenous Matrix Deposition. Biomaterials. 26(15): 2479-2489. IF: 7.882
  8. Malda J., Woodfield T., van der Vloodt F., Wilson C., Martens DE., Tramper J., van Blitterswijk C.A., Riesle J. (2005). The Effect of PEGT/PBT Scaffold Architecture on the Composition of Tissue Engineered Cartilage. Biomaterials. 26(1): 63-72. IF: 7.882
  9. Woodfield T., de Wijn JR., Péters F., Riesle J., van Blitterswijk C.A. (2004). Design of Porous Scaffolds for Cartilage Tissue Engineering using a 3-Dimensional Fibre Deposition Technique. Biomaterials. 25(18): 4149-4161. IF: 7.882
  10. Woodfield T., Bezemer JM., Pieper JS., van Blitterswijk C.A., Riesle J. (2002). Scaffolds for tissue engineering of cartilage. Critical Reviews in Eukaryotic Gene Expression, 12(3): 209-236. IF: 4.111

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Publications

Groll, J., Boland, T., Blunk, T., Burdick, J. A., Cho, D.-W., Dalton, P. D., … Woodfield, T. B. F., … Malda, J. (2016). Biofabrication: Reappraising the definition of an evolving field [Perspective]. Biofabrication, 8(1), 013001. doi: 10.1088/1758-5090/8/1/013001

Rajendran, K., Löbker, C., Schon, B. S., Bateman, C. J., Raja, A. Y., de Ruiter, N. J. A., … Ramyar, M., Hooper, G. J., Butler, A. P. H., Woodfield, T. B. F., & Anderson, N. G. (2016). Quantitative imaging of excised osteoarthritic cartilage using spectral CT. European Radiology. Advance online publication. doi: 10.1007/s00330-016-4374-7

Schon, B. S., Hooper, G. J., & Woodfield, T. B. F. (2016). Modular tissue assembly strategies for biofabrication of engineered cartilage. Annals of Biomedical Engineering. Advance online publication. doi: 10.1007/s10439-016-1609-3

Schuurman, W., Harimulyo, E. B., Gawlitta, D., Woodfield, T. B. F., Dhert, W. J. A., van Weeren, P. R., & Malda, J. (2016). Three-dimensional assembly of tissue-engineered cartilage constructs results in cartilaginous tissue formation without retainment of zonal characteristics. Journal of Tissue Engineering & Regenerative Medicine, 10(4), 315-324. doi: 10.1002/term.1726

Lim, K., Levato, R., Costa, P., Castilho, M., Dorenmalen, K., Melchels, F., … Woodfield, T. (2016). Biofabrication of hydrogel based "bio resins" via high resolution digital light processing. Proceedings of the 10th World Biomaterials Congress (WBS). (pp. 2691). Retrieved from http://www.wbc2016.org/

Chapter in Book - Research

Hutmacher, D. W., Woodfield, T. B. F., & Dalton, P. D. (2015). Scaffold design and fabrication. In C. A. van Blitterswijk & J. de Boer (Eds.), Tissue engineering. (2nd ed.) (pp. 311-346). London, UK: Academic Press. doi: 10.1016/B978-0-12-420145-3.00010-9

Melchels, F., Malda, J., Fedorovich, N., Alblas, J., & Woodfield, T. (2011). Organ printing. In P. Ducheyne, K. E. Healy, D. W. Hutmacher, D. W. Grainger & C. J. Kirkpatrick (Eds.), Comprehensive biomaterials (vol. 5). (pp. 587-606). Elsevier Science.

Malda, J., Radisic, M., Levenberg, S., Woodfield, T., Bomens, C., Baaijens, F., … Vunjak-Novakovic, G. (2008). Cell nutrition. In C. van Blitterswijk (Ed.), Tissue engineering. (pp. 327-362). London, UK: Academic Press.

Hutmacher, D., Woodfield, T., Dalton, P., & Lewis, J. (2008). Scaffold design and fabrication. In C. van Blitterswijk (Ed.), Tissue engineering. (pp. 403-454). London, UK: Academic Press.

Habibovic, P., Woodfield, T., de Groot, K., & van Blitterswijk, C. (2006). Predictive value of in vitro and in vivo assays in bone and cartilage repair: What do they really tell us about the clinical performance? In J. P. Fisher (Ed.), Advances in Experimental Medicine & Biology: Tissue engineering (Vol. 585). (pp. 327-360). New York: Springer. doi: 10.1007/978-0-387-34133-0_22

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Journal - Research Article

Groll, J., Boland, T., Blunk, T., Burdick, J. A., Cho, D.-W., Dalton, P. D., … Woodfield, T. B. F., … Malda, J. (2016). Biofabrication: Reappraising the definition of an evolving field [Perspective]. Biofabrication, 8(1), 013001. doi: 10.1088/1758-5090/8/1/013001

Schuurman, W., Harimulyo, E. B., Gawlitta, D., Woodfield, T. B. F., Dhert, W. J. A., van Weeren, P. R., & Malda, J. (2016). Three-dimensional assembly of tissue-engineered cartilage constructs results in cartilaginous tissue formation without retainment of zonal characteristics. Journal of Tissue Engineering & Regenerative Medicine, 10(4), 315-324. doi: 10.1002/term.1726

Schon, B. S., Hooper, G. J., & Woodfield, T. B. F. (2016). Modular tissue assembly strategies for biofabrication of engineered cartilage. Annals of Biomedical Engineering. Advance online publication. doi: 10.1007/s10439-016-1609-3

Rajendran, K., Löbker, C., Schon, B. S., Bateman, C. J., Raja, A. Y., de Ruiter, N. J. A., … Ramyar, M., Hooper, G. J., Butler, A. P. H., Woodfield, T. B. F., & Anderson, N. G. (2016). Quantitative imaging of excised osteoarthritic cartilage using spectral CT. European Radiology. Advance online publication. doi: 10.1007/s00330-016-4374-7

Mutreja, I., Woodfield, T. B. F., Sperling, S., Nock, V., Evans, J. J., & Alkaisi, M. M. (2015). Positive and negative bioimprinted polymeric substrates: New platforms for cell culture. Biofabrication, 7, 025002. doi: 10.1088/1758-5090/7/2/025002

Schrobback, K., Klein, T. J., & Woodfield, T. B. F. (2015). The importance of connexin hemichannels during chondroprogenitor cell differentiation in hydrogel versus microtissue culture models. Tissue Engineering Part A, 21(11-12), 1785-1794. doi: 10.1089/ten.tea.2014.0691

Nunnerley, J., Dunn, J., McPherson, K., Hooper, G., & Woodfield, T. (2015). Participation and quality of life outcomes among individuals with earthquake-related physical disability: A systematic review. Journal of Rehabilitation Medicine. doi: 10.2340/16501977-1965

Selvarajah, E., Hooper, G., Grabowski, K., Frampton, C., Woodfield, T. B. F., & Inglis, G. (2015). The rates of wear of X3 highly cross-linked polyethylene at five years when coupled with a 36 mm diameter ceramic femoral head in young patients. Bone & Joint Journal, 97-B(11), 1470-1474. doi: 10.1302/0301-620x.97b11.35736

Chen, F., Hochleitner, G., Woodfield, T., Groll, J., Dalton, P., & Amsdem, B. G. (2015). Additive manufacturing of a photo-cross-linkable polymer via direct melt electrospinning writing for producing high strength structures. Biomacromolecules. Advance online publication. doi: 10.1021/acs.biomac.5b01316

Nunnerley, J., Dunn, J., McPherson, K., Hooper, G., & Woodfield, T. (2015). Return to work for severely injured survivors of the Christchurch earthquake: Influences in the first 2 years. Disability & Rehabilitation. Advance online publication. doi: 10.3109/09638288.2015.1070299

Rajendran, K., Walsh, M. F., de Ruiter, N. J. A., Chernoglazov, A. I., Panta, R. K., Butler, A. P. H., … Anderson, N. G., Woodfield, T. B. F., Tredinnick, S. J., … Bateman, C. J., Aamir, R., … Smithies, D. J., Mohr, J. L., … Ronaldson, J. P., … Atharifard, A., … Schleich, N., & Billinghurst, M. (2014). Reducing beam hardening effects and metal artefacts in spectral CT using Medipix3RX. Journal of Instrumentation, 9, P03015. doi: 10.1088/1748-0221/9/03/P03015

Shadanbaz, S., Walker, J., Woodfield, T. B. F., Staiger, M. P., & Dias, G. J. (2014). Monetite and brushite coated magnesium: In vivo and in vitro models for degradation analysis. Journal of Materials Science: Materials in Medicine, 25(1), 173-183. doi: 10.1007/s10856-013-5059-2

Walker, J., Shadanbaz, S., Woodfield, T. B. F., Staiger, M. P., & Dias, G. J. (2014). The in vitro and in vivo evaluation of the biocompatibility of Mg alloys. Biomedical Materials, 9, 015006. doi: 10.1088/1748-6041/9/1/015006

Walker, J., Shadanbaz, S., Woodfield, T. B. F., Staiger, M. P., & Dias, G. J. (2014). Magnesium biomaterials for orthopedic application: A review from a biological perspective. Journal of Biomedical Materials Research Part B, 102(6), 1316-1331. doi: 10.1002/jbm.b.33113

Aamir, R., Chernoglazov, A., Bateman, C. J., Butler, A. P. H., Butler, P. H., Anderson, N. G., … Panta, R. K., … Mohr, J. L., Rajendran, K., Walsh, M. F., de Ruiter, N. J. A., Gieseg, S. P., Woodfield, T., … Schleich, N., Scott, N., … Ronaldson, J. P., Cook, N. J., … Hodge, K. (2014). MARS spectral molecular imaging of lamb tissue: Data collection and image analysis. Journal of Instrumentation, 9, P02005. doi: 10.1088/1748-0221/9/02/P02005

Emans, P. J., Jansen, E. J. P., van Iersel, D., Welting, T. J. M., Woodfield, T. B. F., Bulstra, S. K., … Kuijer, R. (2013). Tissue-engineered constructs: The effect of scaffold architecture in osteochondral repair. Journal of Tissue Engineering & Regenerative Medicine, 7(9), 751-756. doi: 10.1002/term.1477

Schrobback, K., Wrobel, J., Hutmacher, D. W., Woodfield, T. B. F., & Klein, T. J. (2013). Stage-specific embryonic antigen-4 is not a marker for chondrogenic and osteogenic potential in cultured chondrocytes and mesenchymal progenitor cells. Tissue Engineering Part A, 19(11-12), 1316-1326. doi: 10.1089/ten.tea.2012.0496

Selvarajah, E., Hooper, G. J., Woodfield, T. B. F., Inglis, G., & Frampton, C. (2013). Measurement of early wear rates with X3 polyethylene and 36-mm femoral heads in young patients: A prospective study. Current Orthopaedic Practice, 24(6), 641-646. doi: 10.1097/BCO.0b013e31829cc4c9

Walker, J., Shadanbaz, S., Kirkland, N. T., Stace, E., Woodfield, T., Staiger, M. P., & Dias, G. J. (2012). Magnesium alloys: Predicting in vivo corrosion with in vitro immersion testing. Journal of Biomedical Materials Research Part B, 100B(4), 1134-1141. doi: 10.1002/jbm.b.32680

Nguyen, T. L., Blanquet, A., Staiger, M. P., Dias, G. J., & Woodfield, T. B. F. (2012). On the role of surface roughness in the corrosion of pure magnesium in vitro. Journal of Biomedical Materials Research Part B, 100 B(5), 1310-1318.

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