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Professor Brian A. Darlow

Brian Darlow

MA MB BChir MD (Cantab) FRCP FRCPCH

Email brian.darlow@otago.ac.nz

Tel 64 3 364 0747

Brian Darlow trained in the United Kingdom and New Zealand, with a spell in Papua New Guinea.

He returned to the department as Senior Lecturer in 1982 and was appointed to the Chair of Paediatrics in 2001.

He is a clinical neonatologist and his research interests include free radical disease in the newborn and the epidemiology and outcome of complications of prematurity.

He is also consultant in charge of the paediatric diabetic clinic.

Interests outside of medicine include ornithology and tramping.

Brian Darlow is the CureKids Chair of Paediatric Research at the University of Otago, Christchurch.

NZ Very Low Birthweight study

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Publications

Darlow, B. A., Lui, K., Kusuda, S., Reichman, B., Håkansson, S., Bassler, D., … on behalf of the International Network for Evaluating Outcomes of Neonates (iNeo). (2017). International variations and trends in the treatment for retinopathy of prematurity. British Journal of Ophthalmology. Advance online publication. doi: 10.1136/bjophthalmol-2016-310041

Zahari, M., Lee, D. S., & Darlow, B. A. (2016). Algorithms that eliminate the effects of calibration artefact and trial-imposed offsets of Masimo oximeter in BOOST-NZ trial. Journal of Clinical Monitoring & Computing, 30, 669-678. doi: 10.1007/s10877-015-9752-1

Gemmell, L., Martin, L., Murphy, K. E., Modi, N., Håkansson, S., Reichman, B., … Darlow, B. A., … for the International Network for Evaluating Outcomes (iNEO) of Neonates Investigators. (2016). Hypertensive disorders of pregnancy and outcomes of preterm infants of 24 to 28 weeks' gestation. Journal of Perinatology, 36, 1067-1072. doi: 10.1038/jp.2016.133

Harris, S. L., Austin, N. C., Battin, M., Broadbent, R., Horwood, J., Keenan, R., … Graham, P., Woodward, L. J., & Darlow, B. A. (2016). In-hospital morbidity and brain metrics of preterm neonates born 1998–2009. New Zealand Medical Journal, 129(1440), 94-107. Retrieved from https://www.nzma.org.nz/journal

Darlow, B. A., Voss, L., Lennon, D. R., & Grimwood, K. (2016). Early-onset neonatal group B streptococcus sepsis following national risk-based prevention guidelines. Australian & New Zealand Journal of Obstetrics & Gynaecology, 56, 69-74. doi: 10.1111/ajo.12378

Chapter in Book - Research

Darlow, B. (2012). The newborn infant: Stabilization and examination. In M. South & D. Isaacs (Eds.), Practical paediatrics. (7th ed.) (pp. 328-340). Edinburgh, UK: Churchill Livingstone.

Begg, E. J., Atkinson, H. C., & Darlow, B. A. (1997). Guide to drug usage in lactation. In T. M. Speight & N. H. G. Holford (Eds.), Avery's Drug Treatment: a Guide to the Properties, Choice, Therapeutic Use and Economic Value of Drugs in Disease Management, 4th edition. (pp. 1701-1723). Auckland: Adis Press.

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Chapter in Book - Other

Darlow, B. (2013). Neonatal Health. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 88-95). Christchurch, New Zealand: University of Otago.

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Journal - Research Article

Darlow, B. A., Lui, K., Kusuda, S., Reichman, B., Håkansson, S., Bassler, D., … on behalf of the International Network for Evaluating Outcomes of Neonates (iNeo). (2017). International variations and trends in the treatment for retinopathy of prematurity. British Journal of Ophthalmology. Advance online publication. doi: 10.1136/bjophthalmol-2016-310041

Zahari, M., Lee, D. S., & Darlow, B. A. (2016). Algorithms that eliminate the effects of calibration artefact and trial-imposed offsets of Masimo oximeter in BOOST-NZ trial. Journal of Clinical Monitoring & Computing, 30, 669-678. doi: 10.1007/s10877-015-9752-1

Darlow, B. A., Voss, L., Lennon, D. R., & Grimwood, K. (2016). Early-onset neonatal group B streptococcus sepsis following national risk-based prevention guidelines. Australian & New Zealand Journal of Obstetrics & Gynaecology, 56, 69-74. doi: 10.1111/ajo.12378

Harris, S. L., Austin, N. C., Battin, M., Broadbent, R., Horwood, J., Keenan, R., … Graham, P., Woodward, L. J., & Darlow, B. A. (2016). In-hospital morbidity and brain metrics of preterm neonates born 1998–2009. New Zealand Medical Journal, 129(1440), 94-107. Retrieved from https://www.nzma.org.nz/journal

Gemmell, L., Martin, L., Murphy, K. E., Modi, N., Håkansson, S., Reichman, B., … Darlow, B. A., … for the International Network for Evaluating Outcomes (iNEO) of Neonates Investigators. (2016). Hypertensive disorders of pregnancy and outcomes of preterm infants of 24 to 28 weeks' gestation. Journal of Perinatology, 36, 1067-1072. doi: 10.1038/jp.2016.133

Martin, L. J., Sjörs, G., Reichman, B., Darlow, B. A., Morisaki, N., Modi, N., … on behalf of the International Network for Evaluating Outcomes (iNeo) of Neonates Investigators. (2016). Country-specific vs. common birthweight-for-gestational age references to identify small for gestational age infants born at 24–28 weeks: An international study. Paediatric & Perinatal Epidemiology, 30(5), 450-461. doi: 10.1111/ppe.12298

Hossain, S., Shah, P. S., Ye, X. Y., Darlow, B. A., Lee, S. K., Lui, K., on behalf of the Canadian Neonatal Network, and Australian and New Zealand Neonatal Network. (2016). Outborns or inborns: Where are the differences? A comparison study of very preterm neonatal intensive care unit infants cared for in Australia and New Zealand and in Canada. Neonatology, 109(1), 76-84. doi: 10.1159/000441272

Boost-II Australia and United Kingdom Collaborative Groups, including Darlow, B. A. (2016). Outcomes of two trials of oxygen-saturation targets in preterm infants. New England Journal of Medicine, 374(8), 749-760. doi: 10.1056/NEJMoa1514212

Shah, P. S., Lui, K., Sjörs, G., Mirea, L., Reichman, B., Adams, M., … Darlow, B. A., … for the investigators of the International Network for Evaluating Outcomes (iNeo) of Neonates. (2016). Neonatal outcomes of very low birth weight and very preterm neonates: An international comparison. Journal of Pediatrics, 177, 144-152. doi: 10.1016/j.jpeds.2016.04.083

Gilbert, C., Wormald, R., Fielder, A., Deorari, A., Zepeda-Romero, L. C., Quinn, G., … Darlow, B. (2016). Potential for a paradigm change in the detection of retinopathy of prematurity requiring treatment. Archives of Disease in Childhood: Fetal & Neonatal Edition, 101(1), F6-F9. doi: 10.1136/archdischild-2015-308704

Darlow, B. A., Graham, P. J., & Rojas-Reyes, M. X. (2016). Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birth weight infants (Review). Cochrane Database of Systematic Reviews, 8, CD000501. doi: 10.1002/14651858.CD000501.pub4

Chawla, D., & Darlow, B. A. (2016). Anti-vascular endothelial growth factor preparations in the treatment of retinopathy of prematurity: Balancing risks and benefits. Indian Pediatrics, 53(Suppl. 2), S129-S136.

Guillén, U., Weiss, E. M., Munson, D., Maton, P., Jefferies, A., Norman, M., … Darlow, B., & Kirpalani, H. (2015). Guidelines for the management of extremely premature deliveries: A systematic review. Pediatrics, 136(2), 343-350. doi: 10.1542/peds.2015-0542

Hossain, S., Shah, P. S., Ye, X. J., Darlow, B. A., Lee, S. K., Lui, K., on behalf of the Canadian Neonatal Network, and Australian and New Zealand Neonatal Network. (2015). Outcome comparison of very preterm infants cared for in the neonatal intensive care units in Australia and New Zealand and in Canada. Journal of Paediatrics & Child Health, 51, 881-888. doi: 10.1111/jpc.12863

Tan, Z., Chong, C., Darlow, B., & Dai, S. (2015). Visual impairment due to retinopathy of prematurity (ROP) in New Zealand: A 22-year review. British Journal of Ophthalmology, 99, 801-806. doi: 10.1136/bjophthalmol-2014-305913

Darlow, B. A. (2015). Retinopathy of prematurity: New developments bring concern and hope. Journal of Paediatrics & Child Health, 51(8), 765-770. doi: 10.1111/jpc.12860

Darlow, B. A., & Morley, C. J. (2015). Oxygen saturation targeting and bronchopulmonary dysplasia. Clinics in Perinatology, 42(4), 807-823. doi: 10.1016/j.clp.2015.08.008

Mulder, R. T., Carter, J. D., Frampton, C. M. A., & Darlow, B. A. (2014). Good two-year outcome for parents whose infants were admitted to a neonatal intensive care unit. Psychosomatics, 55(6), 613-620. doi: 10.1016/j.psym.2013.12.007

Reid, R. A., Prickett, T. C. R., Pullar, B. E., Darlow, B. A., Gullam, J. E., & Espiner, E. A. (2014). C-type natriuretic peptide in complicated pregnancy: Increased secretion precedes adverse events. Journal of Clinical Endocrinology & Metabolism, 99(4), 1470-1478. doi: 10.1210/jc.2013-3758

Gilbert, C., Darlow, B., Zin, A., Sivasubramaniam, S., Shah, S., Gianini, N., … Lopes Moreira, M. E. (2014). Educating neonatal nurses in Brazil: A before-and-after study with interrupted time series analysis. Neonatology, 106(3), 201-208. doi: 10.1159/000362532

Darlow, B. A., Marschner, S. L., Donoghoe, M., Battin, M. R., Broadbent, R. S., Elder, M. J., Hewson, M. P., … Graham, P., McNeill, N. J., … on behalf of the Benefits Of Oxygen Saturation Targeting-New Zealand (BOOST-NZ) Collaborative Group. (2014). Randomized controlled trial of oxygen saturation targets in very preterm infants: Two year outcomes. Journal of Pediatrics, 165(1), 30-35. doi: 10.1016/j.jpeds.2014.01.017

Porter, J. A., MacKenzie, K., Darlow, B., & Day, A. S. (2014). Looking for coeliac disease in children with type 1 diabetes mellitus. Journal of Paediatrics & Child Health, 50(10), 811-816. doi: 10.1111/jpc.12643

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