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Carney Centre for Pharmacogenomics Publications

2017 2016 2015

2017

Adehin, A., Bolaji, O.O., Maggo, S., Kennedy, M.A. (2017) Phenotype-genotype correlation for CYP1A2 and CYP2A6 in Nigerians. Drug Metabolism and Personalized Therapy (Accepted)

Stevens, A.J., Taylor, M.G., Pearce, F.G., Kennedy, M.A. (2017) Allelic Drop-Out During Polymerase Chain Reaction due to G-Quadruplex Structures and DNA Methylation Is Widespread at Imprinted Human Loci. G3 Early Online January 30, 2017, doi:10.1534/g3.116.038687

Adehin, A., Bolaji, O.O., Kennedy, M.A. (2017) Polymorphisms in CYP2C8 and CYP3A5 genes in the Nigerian population. Drug Metabolism and Pharmacokinetics (In Press) [IF=1.8]

Stevens, A. J., & Kennedy, M. A. (2017). Structural analysis of G-quadruplex formation at the human MEST promoter. PLoS ONE, 12(1), e0169433. doi: 10.1371/journal.pone.0169433

Adehin, A., Bolaji,O.O., Kennedy, M.A., Adeagbo, B.A. (2017) Allele frequencies of thiopurine S-methyltransferase (TPMT) variants in the Nigerian population. Polish Annals of Medicine. (In Press)

Bagshaw, A., Horwood, J., Fergusson,D., Gemmell, N., Kennedy, M. (2017) Microsatellite polymorphisms associated with human behavioural and psychological phenotypes including a gene-environment interaction. BMC Medical Genetics. (In Press)

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2016

Stevens, A., Appleby, S., Kennedy, M. (2016) Many commercial hot-start polymerases demonstrate activity prior to thermal activation. Biotechniques 61, 293-296.

Appleby, S, Pearson, J.F, Aitchison, A, Spittlehouse, J.K, Joyce, P.R, Kennedy, M.A (2016) Mean telomere length is not associated with current health status in a 50 year old population sample. American Journal of Human Biology [doi: 10.1002/ajhb.22906, Epub ahead of print]

Cree, S.L., Fredericks, R., Miller, A.L., Pearce, F.G., Filichev, V., Fee, C., Kennedy, M.A. (2016). DNA G-quadruplexes show strong interaction with DNA methyl transferases in vitro. FEBS Letters 590, 2870-83.

Stevens AJ, Kennedy HL, Kennedy MA. (2016) Fluorescent methods for probing G-quadruplex structure in single and double stranded DNA. Biochemistry 55, 3714-25.

Foulds, J.A., Maggo, S., Kennedy, M.A. (2016) Personalised prescribing in psychiatry: has pharmacogenomics delivered on its promise? Aust NZ J Psychiatry 50, 509-10 [IF=3.4]

Chua EW, Cree SL, Ton KNT, Lehnert K, Shepherd P, Helsby N, Kennedy MA (2016) Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX ADME PGx Panel for Pharmacogenomic Profiling. Front. Pharmacol. 7:1. doi: 10.3389/fphar.2016.00001.

Maggo, S.D.S, Savage, R.L., Kennedy, M.A. (2016) Impact of new genomic technologies on understanding adverse drug reactions. Clinical Pharmacokinetics 55, 419-436.

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2015

Bridgman PG, Finsterer J, Lacey C, Kimber B, Parkin PJ, Miller AL, Kennedy MA. (2015) CTG-repeat expansions in the DMPK gene do not cause takotsubo syndrome. Int J Cardiol. 203:107-108.

Maggo, S.D.S, Savage, R.L., Kennedy, M.A. (2015) Impact of new genomic technologies on understanding adverse drug reactions. Clinical Pharmacokinetics [Epub ahead of print]. 

Morris, RW, Taylor, AE, Fluharty, ME, Bjørngaard, JH, Åsvold, BO, Gabrielsen, ME, Campbell, A, Marioni, R, Kumari, M, Korhonen, T, Männistö, S, Marques-Vidal, P, Kaakinen, M, Cavadino, A, Postmus, I, Husemoen, LLN, Skaaby, T, Ahluwalia, TVS, Treur, JL, Willemsen, G, Dale, C, Wannamethee, SG, Lahti, J, Palotie, A, Räikkönen, K, McConnachie, A, Padmanabhan, S, Wong, A, Dalgård, C, Paternoster, L, Ben-Shlomo, Y, Tyrrell, J, Horwood, J, Fergusson, DM, Kennedy, MA, Nohr, EA, Christiansen, L, Kyvik, KO, Kuh, D, Watt, G, Eriksson, JG, Whincup, PH, Vink, JM, Boomsma, DI, Smith, GD, Lawlor, D, Linneberg, A, Ford, I, Jukema, JW, Power, C, Hyppönen, E, Jarvelin, M-R, Preisig, M, Borodulin, K, Kaprio, J, Kivimaki, M, Smith, BH, Hayward, C, Romundstad, PR, Sørensen, TIA, Munafò, MR & Sattar, N (2015) Heavier smoking may lead to relative increase in waist circumference: evidence for causal relationship from Mendelian randomisation meta-analysis. The CARTA consortium BMJ Open. 5:e008808 doi:10.1136/bmjopen-2015-008808

Adkins, D. E., Clark, S. L., Copeland, W. E., Kennedy, M., Conway, K., Angold, A., Maes, H., Liu, Y., Kumar, G., Erkanli, A., Patkar, A. A., Silberg, J., Brown, T. H., Fergusson, D. M., Horwood, L. J., Eaves, L., van den Oord, E. J., Sullivan, P. F., and Costello, E. J. (2015) Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood. Twin Res Hum Genet 18, 335-347.

Balasubramanian, D., Deng, A. X., Doudney, K., Hampton, M. B., and Kennedy, M. A. (2015) Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line. Neuropharmacology 99, 79-88.

Chua, E.W., Miller, A.L., Kennedy, MA. (2015) Choice of PCR microtube can impact on the success of long-range PCRs. Analytical Biochemistry: Methods in the Biological Sciences 477:115-117.

Chua,E.W., Cree, S., Barclay, M.L., Doudney, K., Lehnert, K., Aitchison, A., Kennedy, M.A. (2015) Exome sequencing and array comparative genomic hybridisation analysis of preferential 6-methylmercaptopurine producers. The Pharmacogenomics Journal 15, 414-421.

Foulds, J.A., Ton, K., Kennedy, M.A., Adamson, S.J., Mulder, R.T., Sellman, J.D. (2015) OPRM1 genotype and naltrexone treatment outcome in depressed alcohol dependent patients. Pharmacogenetics and Genomics 25, 270-273.

Jodczyk, S., Pearson, J.F., Aitchison, A., Miller, A.L., Hampton, M.B., Kennedy, M.A. (2015). Telomere length measurement on the Roche LightCycler® 480 platform. Genetic Testing and Molecular Biomarkers 19 (2) 1-6.

Larsen, PD, LR Johnston, A Holley, A La Flamme, L Smyth, EW Chua, MA Kennedy, SA Harding. (2015). Prevalence and significance of CYP2C19*2 and CYP2C19*17 alleles in a New Zealand acute coronary syndrome population. Internal Medicine Journal 45, 537–545.

Davis JM, Searles VB, Anderson N, Keeney J, Raznahan A, Horwood LJ, Fergusson DM, Kennedy MA, Giedd J, Sikela JM. (2015). DUF1220 copy number is linearly associated with increased cognitive function as measured by total IQ and mathematical aptitude scores. Human Genetics 134, 67-75.

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