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MICR334 Advanced Immunology

Mechanisms of immune activation and tolerance, molecular immunology, allergy, autoimmunity, immunodeficiency, immunoendocrinology, tumour immunotherapy and transplant immunology. Tools for tumour immunotherapy, fluorescent cell sorting, lymphocyte activation, cytotoxicity and cytokine assays.

The immune system helps determine how our bodies respond to infections, allergens, transplantation and cancer. Understanding how it functions is essential for the development of effective vaccines and treatments. This paper will demonstrate how the immune system functions and give you the opportunity to see how your knowledge can be applied. A course in immunology opens up career possibilities in fields as diverse as influenza vaccine development, cancer immunology and autoimmunity. This course will build on your fundamental knowledge of immunology. This paper is ideal if you want to explore and develop your understanding of the immune system, and investigate the application of immunology knowledge at the interface between disease and the host response to disease.

Paper title Advanced Immunology
Paper code MICR334
Subject Microbiology
EFTS 0.1500
Points 18 points
Teaching period First Semester
Domestic Tuition Fees (NZD) $1,018.05
International Tuition Fees (NZD) $4,500.00

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Prerequisite
MICR 223
Recommended Preparation
MICR 221
Schedule C
Science
Eligibility
Appropriate for BSc or BBiomedSc students
Contact
Dr Roslyn Kemp: roslyn.kemp@otago.ac.nz
Teaching staff
Convenor: Dr Roslyn Kemp
Other Lecturers: Associate Professor Alex McLellan, Dr Jo Kirman and Megan Hall
Paper Structure
The lectures focus on:
  • Comparative Immunity and Innate Immune Responses
  • Antigen Recognition and Presentation
  • Lab Preparation
  • Immune Regulation
  • B Cell Immunology
  • Vaccines

The laboratory course investigates cancer immunotherapy. In these labs, you will work in groups to design and carry out an immunotherapy for melanoma. You will design an experimental approach to treat melanoma, prepare the treatment and measure its effectiveness. Several protocols will be provided to help you.
Assessment:
  • Poster for Practical Component?á 20%
  • Blackboard Quiz on lab content 10%
  • Final Exam?á70%
Teaching Arrangements
24 lectures
4 weeks of practical work (12 hours/week)

There are two lectures per week for all weeks of the first semester. There is one laboratory session per week, with each laboratory session running over 2-4 days. Students may leave the lab for other commitments, such as lectures, and are able to plan their experiments to fit in with these commitments. The laboratory classes run in weeks 5-8 of the first semester.
Textbooks
Either:
Kuby Immunology by Thomas J. Kindt, Barbara A. Osborne, Richard A. Goldsby (6th Edition)
Or:
Immunobiology: the immune system in health and disease (7th or 8th Edition) by Janeway C. and Travers P, Blackwell Scientific Publications
Course outline
View course outline for MICR 334
Graduate Attributes Emphasised
Scholarship, Communication, Critical thinking, Ethics, Information literacy, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes
  • Build on fundamental knowledge of immunology.
  • Investigate the application of immunology knowledge at the interface between disease and the host response to disease.

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Timetable

First Semester

Location
Dunedin
Teaching method
This paper is taught On Campus
Learning management system
Blackboard

Lecture

Stream Days Times Weeks
Attend
L1 Tuesday 13:00-13:50 9-15, 18-22
Friday 13:00-13:50 9-14, 17-22

Practical

Stream Days Times Weeks
Attend
P1 Tuesday 14:00-17:50 13-15
Wednesday 09:00-17:50 13-15, 17

Mechanisms of immune activation and tolerance, molecular immunology, allergy, autoimmunity, immunodeficiency, immunoendocrinology, tumour immunotherapy and transplant immunology. Tools for tumour immunotherapy, fluorescent cell sorting, lymphocyte activation, cytotoxicity and cytokine assays.

The immune system helps determine how our bodies respond to infections, allergens, transplantation and cancer. Understanding how it functions is essential for the development of effective vaccines and treatments for diseases like cancer and autoimmunity. This paper will demonstrate how the immune system functions and give you the opportunity to see how your knowledge can be applied.
A course in immunology opens up career possibilities in fields as diverse as influenza vaccine development, cancer immunotherapy and immunisation education. This course will build on your fundamental knowledge of immunology. This paper is ideal if you want to explore and develop your understanding of the immune system, and investigate the application of immunology knowledge at the interface between disease and the host response to disease.

Paper title Advanced Immunology
Paper code MICR334
Subject Microbiology
EFTS 0.1500
Points 18 points
Teaching period First Semester
Domestic Tuition Fees Tuition Fees for 2018 have not yet been set
International Tuition Fees Tuition Fees for international students are elsewhere on this website.

^ Top of page

Prerequisite
MICR 223
Recommended Preparation
MICR 221
Schedule C
Science
Eligibility
Appropriate for BSc or BBiomedSc students.
Contact
Associate Professor Roslyn Kemp: roslyn.kemp@otago.ac.nz
Teaching staff
Convenor: Associate Professor Roslyn Kemp
Other Lecturers: Associate Professor Alex McLellan, Dr Jo Kirman and Megan Hall
Paper Structure
The lectures focus on:
  • Comparative Immunity and Innate Immune Responses
  • Antigen Recognition and Presentation
  • Lab Preparation
  • Immune Regulation
  • B Cell Immunology
  • Vaccines
The laboratory course investigates T cells and how they can change in different environments. In these labs, you will work in groups and carry out experiments to try and change T cells from one type to another type. You will then work out how these T cells could be used to treat disease. Several protocols will be provided to help you.
Teaching Arrangements
24 lectures
4 weeks of practical work (12 hours/week)

There are two lectures per week for all weeks of the first semester. There is one laboratory session per week, with each laboratory session running over 2-4 days. Students may leave the lab for other commitments, such as lectures, and are able to plan their experiments to fit in with these commitments. The laboratory classes run in weeks 5-8 of the first semester.
Textbooks
Either:
Kuby Immunology by Thomas J. Kindt, Barbara A. Osborne, Richard A. Goldsby (6th Edition)
Or:
Immunobiology: the immune system in health and disease (7th or 8th Edition) by Janeway C. and Travers P, Blackwell Scientific Publications
Course outline
View course outline for MICR 334
Graduate Attributes Emphasised
Scholarship, Communication, Critical thinking, Ethics, Information literacy, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes
  • Build on fundamental knowledge of immunology.
  • Investigate the application of immunology knowledge at the interface between disease and the host response to disease.

^ Top of page

Timetable

First Semester

Location
Dunedin
Teaching method
This paper is taught On Campus
Learning management system
Blackboard

Lecture

Stream Days Times Weeks
Attend
L1 Tuesday 13:00-13:50 9-13, 15-22
Friday 13:00-13:50 9-12, 15-22

Practical

Stream Days Times Weeks
Attend
P1 Tuesday 14:00-17:50 13, 15-17
Wednesday 09:00-17:50 13, 15-16