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    Overview

    Introduces the core concepts of pharmacology and toxicology. Students will study the science behind the use of medicines, as well as cover topics on environmental and clinical toxicology.

    PHAL 211 will introduce you to the wonderful field of pharmacology. The paper begins with basic pharmacological principles dealing with how drugs act (i.e. pharmacodynamics) and what the body does to the drug (i.e. pharmacokinetics). From here the lecture topics range from humble paracetamol to the social-changing contraceptives to the mind-altering cocaine. The laboratory classes will teach you essential scientific skills that are required to investigate drug metabolism, both the positive and negative effects of drugs on humans, experimental design and statistics analysis.

    PHAL 211 is essential for further study in Pharmacology; however, the paper content will be useful for other science majors, including Physiology, Anatomy, Biochemistry and Microbiology.

    About this paper

    Paper title Introduction to Pharmacology and Toxicology
    Subject Pharmacology
    EFTS 0.15
    Points 18 points
    Teaching period Semester 2 (On campus)
    Domestic Tuition Fees ( NZD ) $1,173.30
    International Tuition Fees Tuition Fees for international students are elsewhere on this website.
    Prerequisite
    BIOC 192, CHEM 191 and two of BIOL 112, BIOL 123, CELS 191, HUBS 191, HUBS 192, PTWY 131, PTWY 132
    Schedule C
    Science
    Contact

    Course Co-ordinator: Jonathan Falconer (jonathan.falconer@otago.ac.nz)

    Teaching staff

    Associate Professor John Ashton

    Professor Michelle Glass

    Professor Debbie Hay

    Dr Jonathan Falconer

    Paper Structure

    PHAL 211 has both lectures and laboratories.

    Lecture Topics:

    • Action of drugs on the body (ie pharmacodynamics)
    • What the body does to drugs (ie pharmacokinetics)
    • Experimental design and analysis for pharmacology
    • Autonomic nervous system pharmacology
    • Central nervous system pharmacology: Glutamate, GABA, dopamine, serotonin
    • Central nervous system pharmacology: drug dependence
    • Drugs and society
    • Drugs for migraine, diabetes and obesity
    • Inflammation, allergy and pain pharmacology
    • Toxicology

    The laboratories are designed to teach you important laboratories skills and to reinforce concepts introduced in the lectures. Each laboratory is marked as part of the internal assessment.

    Laboratories Topics:

    • Laboratory skills
    • Experimental design and analysis
    • Rat ileum contraction
    • Drug metabolism
    • Adrenergic modulation

    Assessment:

    • Laboratory reports - 20%
    • Terms test- 10%
    • Drug assignment - 10%
    • Final exam - 60%
    Textbooks
    Rang and Dale's Pharmacology. Note that this book is available as an ebook online through the library.
    Graduate Attributes Emphasised
    Interdisciplinary perspective, Lifelong learning, Communication, Critical thinking, Ethics, Information literacy, Research, Self-motivation, Teamwork.
    View more information about Otago's graduate attributes.
    Learning Outcomes
    • To establish a firm understanding of concepts important to the discipline of pharmacology
    • To gain an understanding of pharmacodynamic (what the drug does to the body) and pharmacokinetic (what the body does to the drug - absorption, distribution, metabolism and elimination) processes
    • To introduce experimental design and analyses for pharmacology
    • To introduce autonomic and central nervous system pharmacology
    • To introduce the concepts of drug abuse and drug dependence
    • To introduce the field of toxicology
    • To introduce inflammation, allergy and pain pharmacology
    • Development of critical thinking and collaborative working skills
    • To develop skills in science communications (i.e. drug assignment)

    Timetable

    Semester 2

    Location
    Dunedin
    Teaching method
    This paper is taught On Campus
    Learning management system
    Blackboard

    Lecture

    Stream Days Times Weeks
    Attend
    B1 Tuesday 12:00-12:50 29-35, 37-42
    AND
    D1 Thursday 12:00-12:50 29-35, 37-42
    AND
    E1 Friday 13:00-13:50 29-35, 37-42

    Practical

    Stream Days Times Weeks
    Attend one stream from
    A1 Wednesday 14:00-16:50 30, 32, 34, 38, 40
    A2 Thursday 14:00-16:50 30, 32, 34, 38, 40
    A3 Wednesday 14:00-16:50 31, 33, 35, 39, 41
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