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PHAL303 Neuropharmacology

Mechanisms of action, uses and abuse of drugs affecting the nervous system.

Paper title Neuropharmacology
Paper code PHAL303
Subject Pharmacology
EFTS 0.1500
Points 18 points
Teaching period Second Semester
Domestic Tuition Fees (NZD) $1,018.05
International Tuition Fees (NZD) $4,500.00

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Prerequisite
PHAL 211
Schedule C
Science
Contact
paul.smith@otago.ac.nz
Teaching staff
Associate Professor Steve Kerr
Professor Paul Smith
Paper Structure
PHAL 303 has both lectures and laboratories.

Lecture Topics:
  • Introduction to paper and introduction to CNS neurotransmission
  • AMPA and KA receptors in the CNS
  • NMDA receptors in memory and learning
  • Metabotropic glutamate receptors in the CNS
  • Growth Factors in the CNS
  • Noradrenaline receptors in the CNS
  • GABA receptors in the CNS
  • Drug treatment of epilepsy
  • Histamine receptors in the CNS
  • Serotonin receptors in the CNS
  • Dopamine receptors in the CNS (Parkinson's disease)
  • Dopamine receptors in the CNS (Schizophrenia)
  • ACh receptors in the CNS
  • Neurohormones and volume transmission
  • Drug treatment of anxiety and insomnia
  • Drug treatment of depression
  • Drug therapy of Alzheimer's disease
  • Drug therapy of stroke
  • Drug therapy of multiple sclerosis
  • Growth factors in the CNS
  • Cannabinoid receptors in the CNS
  • Neurotoxicity - MDMA and "P"
  • Advanced neurotoxins
Laboratories Topics:
  • Introduction to lab course and electrophysiological techniques
  • Brain Slice I: Excitation and inhibition
  • Elevated Plus-MazeImage
  • J Analysis
  • Seizures and Stroke
  • Phrenic nerve
Assessment
  • Laboratory reports
    • Image-J Analysis - 9%
    • Brain Slice - 12%
    • Elevated Plus Maze - 12%
    • Phrenic Nerve - 12%
  • Final exam - 55%
Textbooks
Lectures notes
Graduate Attributes Emphasised
Interdisciplinary perspective, Lifelong learning, Scholarship, Communication, Critical thinking, Ethics, Information literacy, Research, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes
  • To understand the physiological and pathological role of neurotransmitter receptors
  • To understand drug treatment of neurological disease
  • To develop critical thinking
  • To develop skills in science communications

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Timetable

Second Semester

Location
Dunedin
Teaching method
This paper is taught On Campus
Learning management system
Blackboard

Lecture

Stream Days Times Weeks
Attend
L1 Tuesday 11:00-11:50 28-34, 36-41
Friday 12:00-12:50 28-34, 36-41

Practical

Stream Days Times Weeks
Attend one stream from
P1 Tuesday 14:00-17:50 29, 32, 34, 37, 39
P2 Tuesday 14:00-17:50 29, 31, 33, 36, 38

Mechanisms of action, uses and abuse of drugs affecting the nervous system.

Paper title Neuropharmacology
Paper code PHAL303
Subject Pharmacology
EFTS 0.1500
Points 18 points
Teaching period Second Semester
Domestic Tuition Fees (NZD) $1,038.45
International Tuition Fees (NZD) $4,680.00

^ Top of page

Prerequisite
PHAL 211
Schedule C
Science
Paper Structure
PHAL 303 has both lectures and laboratories.

Lecture Topics:
  • Introduction to paper and introduction to CNS neurotransmission
  • AMPA and KA receptors in the CNS
  • NMDA receptors in memory and learning
  • Metabotropic glutamate receptors in the CNS
  • Growth Factors in the CNS
  • Noradrenaline receptors in the CNS
  • GABA receptors in the CNS
  • Drug treatment of epilepsy
  • Histamine receptors in the CNS
  • Serotonin receptors in the CNS
  • Dopamine receptors in the CNS (Parkinson's disease)
  • Dopamine receptors in the CNS (Schizophrenia)
  • ACh receptors in the CNS
  • Neurohormones and volume transmission
  • Drug treatment of anxiety and insomnia
  • Drug treatment of depression
  • Drug therapy of Alzheimer's disease
  • Drug therapy of stroke
  • Drug therapy of multiple sclerosis
  • Growth factors in the CNS
  • Cannabinoid receptors in the CNS
  • Neurotoxicity - MDMA and P
  • Advanced neurotoxins
Laboratories Topics:
  • Introduction to lab course and electrophysiological techniques
  • Brain Slice I: Excitation and inhibition
  • Elevated Plus-MazeImage
  • J Analysis
  • Seizures and Stroke
  • Phrenic nerve
Assessment
  • Laboratory reports
    • Image-J Analysis - 9%
    • Brain Slice - 12%
    • Elevated Plus Maze - 12%
    • Phrenic Nerve - 12%
  • Final exam - 55%
Contact
paul.smith@otago.ac.nz
Teaching staff
Associate Professor Steve Kerr
Professor Paul Smith
Textbooks
Lectures notes.
Graduate Attributes Emphasised
Interdisciplinary perspective, Lifelong learning, Scholarship, Communication, Critical thinking, Ethics, Information literacy, Research, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes
  • To understand the physiological and pathological role of neurotransmitter receptors
  • To understand drug treatment of neurological disease
  • To develop critical thinking
  • To develop skills in science communications

^ Top of page

Timetable

Second Semester

Location
Dunedin
Teaching method
This paper is taught On Campus
Learning management system
Blackboard

Lecture

Stream Days Times Weeks
Attend
L1 Tuesday 11:00-11:50 28-34, 36-41
Friday 12:00-12:50 28-34, 36-41

Practical

Stream Days Times Weeks
Attend one stream from
P1 Tuesday 14:00-17:50 29, 32, 34, 37, 39
P2 Tuesday 14:00-17:50 29, 31, 33, 36, 38