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PHCY256 Biopharmaceutical Chemistry

Drug stereochemistry; aromaticity; modulation of reactivity and acid-base properties of drugs; functional group properties and stability in formulation; heterocyclic chemistry; carbohydrates in drugs.

Paper title Biopharmaceutical Chemistry
Paper code PHCY256
Subject Pharmacy
EFTS 0.0950
Points 12 points
Teaching period First Semester
Domestic Tuition Fees (NZD) $745.37
International Tuition Fees (NZD) $3,467.50

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Limited to
BPharm
Contact
david.schmierer@otago.ac.nz
Teaching staff
Mr David Schmierer, Dr Andrea Vernall and Associate Professor Joel Tyndall
Paper Structure
Six 2-week modules

Assessment:
  • Internal 30%
  • Final 70%
Teaching Arrangements
Lectures, laboratories and tutorials
Textbooks
Bruice, PY (2016) Essential Organic Chemistry, 3rd edition, Pearson
Graduate Attributes Emphasised
Lifelong learning, Communication, Critical thinking, Information literacy, Research.
View more information about Otago's graduate attributes.
Learning Outcomes
  • Identify commonly encountered functional groups
  • Predict the acid-base, solubility and stability properties of pharmaceuticals based on structural elements and functional groups
  • Identify and specify stereocentres in pharmaceuticals
  • Identify and specify geometric isomers.
  • Incorporate this stereochemical information as a part of IUPAC nomenclature
  • Identify enantiomers, diastereomers and meso-compounds
  • Predict the presence of aromaticity and any effects this and aromatic substituents may have on pharmaceutical acid-base properties, reactivity and stability
  • Discuss carbohydrates: their stereochemistry, stability and use in Pharmacy

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Timetable

First Semester

Location
Dunedin
Teaching method
This paper is taught On Campus
Learning management system
Blackboard

Lecture

Stream Days Times Weeks
Attend
A1 Monday 10:00-10:50 12, 15
Monday 11:00-11:50 14-15
Monday 12:00-12:50 9, 13
AND
B1 Tuesday 10:00-10:50 21
AND
C1 Wednesday 10:00-10:50 14, 22
Wednesday 11:00-11:50 9, 11, 13, 15, 19-20
Wednesday 12:00-12:50 15, 18
AND
D1 Thursday 09:00-09:50 13
Thursday 10:00-10:50 11, 17
Thursday 11:00-11:50 9, 12-13, 18, 20
Thursday 12:00-12:50 14
AND
E1 Friday 10:00-10:50 20
Friday 11:00-11:50 9, 18-19, 21
Friday 13:00-13:50 17
AND
F1 Monday 11:00-11:50 11

Tutorial

Stream Days Times Weeks
Attend
C1 Wednesday 11:00-11:50 10
Wednesday 13:00-13:50 19
AND
E1 Friday 10:00-10:50 9, 11