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DSM staff profile

Dr Mathew Zacharias

PositionClinical Senior Lecturer
DepartmentDepartment of Surgical Sciences (DSM)
QualificationsMB BS MS PhD FRCA FANZCA DPH
Research summaryClincial pharmacology, evidence-based anaesthesia practice

Research

  • Clinical pharmacology of paracetamol
  • Cochrane reviews on evidence-based anaesthesia practice

Publications

Owens, K. H., Medlicott, N. J., Zacharias, M., Chary, S., Thompson-Fawcett, M., & Reith, D. M. (2012). The pharmacokinetic profile of intravenous paracetamol in adult patients undergoing major abdominal surgery. Therapeutic Drug Monitoring, 34(6), 713-721. doi: 10.1097/FTD.0b013e31826a70ea

Chapter in Book - Research

Zacharias, M., & Chirnside, R. (2006). Anaesthesia for eye, ENT and dental surgery. In A. Møller & T. Pedersen (Eds.), Evidence-based anaesthesia and intensive care. (pp. 271-281). Cambridge University Press.

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Journal - Research Article

Owens, K. H., Medlicott, N. J., Zacharias, M., Chary, S., Thompson-Fawcett, M., & Reith, D. M. (2012). The pharmacokinetic profile of intravenous paracetamol in adult patients undergoing major abdominal surgery. Therapeutic Drug Monitoring, 34(6), 713-721. doi: 10.1097/FTD.0b013e31826a70ea

Reith, D., Medlicott, N. J., Kumara De Silva, R., Yang, L., Hickling, J., & Zacharias, M. (2009). Simultaneous modelling of the Michaelis-Menten kinetics of paracetamol sulphation and glucuronidation. Clinical & Experimental Pharmacology & Physiology, 36(1), 35-42. doi: 10.1111/j.1440-1681.2008.05029.x

Zacharias, M., Conlon, N. P., Herbison, G. P., Sivalingam, P., Walker, R. J., & Hovhannisyan, K. (2008). Interventions for protecting renal function in the perioperative period (Review). Cochrane Database of Systematic Reviews, 4, CD003590. doi: 10.1002/14651858.CD003590.pub3

Zacharias, M., De Silva, R. K., Hickling, J., Medlicott, N. J., & Reith, D. M. (2007). Comparative safety and efficacy of two high dose regimens of oral paracetamol in healthy adults undergoing third molar surgery under local anaesthesia. Anaesthesia & Intensive Care, 35(4), 544-549.

Conlon, N. P., Sullivan, R. P., Herbison, G. P., Zacharias, M., & Buggy, D. J. (2007). The effect of leaving dentures in place on bag-mask ventilation at induction of general anesthesia. Ambulatory Anesthesiology, 105(2), 370-373.

Zacharias, M., Gilmore, I. C. S., Herbison, G. P., Sivalingam, P., & Walker, R. J. (2005). Interventions for protecting renal function in the perioperative period (Review). Cochrane Database of Systematic Reviews, 3. doi: 10.1002/14651858.CD003590.pub2

Zacharias, M., De Silva, R. K., Herbison, P., & Templer, P. (2004). A randomized crossover trial of tenoxicam compared with rofecoxib for postoperative dental pain control. Anaesthesia & Intensive Care, 32(6), 770-774.

Kumara, R., & Zacharias, M. (2002). Effectiveness of tramadol as an analgesic in oral surgery. New Zealand Dental Journal, 98(431), 9-11.

Fawcett, J. P., Kennedy, J., Kumar, A., Ledger, R., Kumara, R., Patel, M., & Zacharias, M. (2002). Comparative efficacy and pharmocokinetics of racemic bupivacaine and S-bupivacaine in third molar surgery. Journal of Pharmacy & Pharmaceutical Sciences, 5(2), 199-204.

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Journal - Research Other

Zacharias, M. (2006). [Review of the book The worst of evils: The fight against pain]. BMJ, 333, 555. doi: 10.1136/bmj.333.7567.555

More publications...