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DSM staff profile

Professor John Crump

PositionMcKinlay Professor of Global Health
DepartmentDepartment of Preventive and Social Medicine (DSM)
QualificationsMB ChB MD DTM&H FRACP FRCPA FRCP
Research summaryInternational health; infectious diseases; medical microbiology; epidemiology; ethics

Research

John Crump is the inaugural McKinlay Chair of Global Health. Professor Crump holds separate qualifications as a medical practitioner (MB ChB and MD), specialist infectious diseases physician (FRACP, FRCP), specialist medical microbiologist (FRCPA), as well as training in tropical medicine (DTM&H) and epidemiology.

From 2002–2011, he lived in Moshi, Tanzania, where he served as Director of Tanzania Operations for the Duke Global Health Institute and Director of the Kilimanjaro Christian Medical Centre (KCMC) Clinical Research Site. In Tanzania he led a large multidisciplinary research program and had a particular research focus on the syndrome of fever and its causes as well as HIV prevention, treatment, and care. He also worked for the US Centers for Disease Control and Prevention, initially as an Epidemic Intelligence Service officer, and then as a medical epidemiologist focusing on enteric diseases, particularly on typhoid fever and other invasive salmonelloses.

Professor Crump has been principal investigator or co-investigator on grants worth more than NZ$25 million since 2002, including through the US National Institutes of Health, the Bill & Melinda Gates Foundation, and the Wellcome Trust. His research interests include the syndrome of fever in resource-limited areas, Salmonella and other invasive bacterial infections, bacterial zoonoses, laboratory capacity and diagnostics in low- and middle-income countries, and ethics in global health.

Peer reviewed articles (PDF 400 KB)
Professor Crump's Inaugural Professorial Lecture (MP4 video 120 MB)

Publications

Marks, F., von Kalckreuth, V., Aaby, P., Adu-Sarkodie, Y., El Tayeb, M. A., Ali, M., … Crump, J. A., … Wierzba, T. F. (2017). Incidence of invasive salmonella disease in sub-Saharan Africa: A multicentre population-based surveillance study. Lancet Global Health, 5(3), e310-e323. doi: 10.1016/s2214-109x(17)30022-0

The Global Burden of Disease Child and Adolescent Health Collaboration, including Crump, J. (2017). Child and adolescent health from 1990 to 2015: Findings from the global burden of diseases, injuries, and risk factors 2015 study. JAMA Pediatrics. Advance online publication. doi: 10.1001/jamapediatrics.2017.0250

Crump, J. A. (2016). Salmonella infections (including enteric fever). In L. Goldman & A. I. Schafer (Eds.), Goldman-Cecil medicine. (25th ed.) Philadelphia, PA: Elsevier Saunders.

Zhang, H. L., Mnzava, K. W., Mitchell, S. T., Melubo, M. L., Kibona, T. J., Cleaveland, S., … Crump, J. A., … Halliday, J. E. B. (2016). Mixed methods survey of zoonotic disease awareness and practice among animal and human healthcare providers in Moshi, Tanzania. PLoS Neglected Tropical Diseases, 10(3), e0004476. doi: 10.1371/journal.pntd.0004476

International Typhoid Consortium, Wong, V. K., Holt, K. E., Okoro, C., Baker, S., Pickard, D. J., … and also Crump, J. A. (2016). Molecular surveillance identifies multiple transmissions of typhoid in West Africa. PLoS Neglected Tropical Diseases, 10(9), e0004781. doi: 10.1371/journal.pntd.0004781

Chapter in Book - Research

Crump, J. A. (2016). Salmonella infections (including enteric fever). In L. Goldman & A. I. Schafer (Eds.), Goldman-Cecil medicine. (25th ed.) Philadelphia, PA: Elsevier Saunders.

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Journal - Research Article

Marks, F., von Kalckreuth, V., Aaby, P., Adu-Sarkodie, Y., El Tayeb, M. A., Ali, M., … Crump, J. A., … Wierzba, T. F. (2017). Incidence of invasive salmonella disease in sub-Saharan Africa: A multicentre population-based surveillance study. Lancet Global Health, 5(3), e310-e323. doi: 10.1016/s2214-109x(17)30022-0

The Global Burden of Disease Child and Adolescent Health Collaboration, including Crump, J. (2017). Child and adolescent health from 1990 to 2015: Findings from the global burden of diseases, injuries, and risk factors 2015 study. JAMA Pediatrics. Advance online publication. doi: 10.1001/jamapediatrics.2017.0250

Zhang, H. L., Mnzava, K. W., Mitchell, S. T., Melubo, M. L., Kibona, T. J., Cleaveland, S., … Crump, J. A., … Halliday, J. E. B. (2016). Mixed methods survey of zoonotic disease awareness and practice among animal and human healthcare providers in Moshi, Tanzania. PLoS Neglected Tropical Diseases, 10(3), e0004476. doi: 10.1371/journal.pntd.0004476

International Typhoid Consortium, Wong, V. K., Holt, K. E., Okoro, C., Baker, S., Pickard, D. J., … and also Crump, J. A. (2016). Molecular surveillance identifies multiple transmissions of typhoid in West Africa. PLoS Neglected Tropical Diseases, 10(9), e0004781. doi: 10.1371/journal.pntd.0004781

Pavllinac, P. B., Lokken, E. M., Watson, J. L., Richardson, B. A., Crump, J. A., & John-Stewart, G. C. (2016). Mycobacterium tuberculosis bacteremia in adults and children: A systematic review and meta-analysis. International Journal of Tuberculosis & Lung Disease, 20(7), 895-902. doi: 10.5588/ijtld.15.0773

Hertz, J. T., Lyaruu, L. J., Ooi, E. E., Mosha, F. W., & Crump, J. A. (2016). Distribution of Aedes mosquitoes in the Kilimanjaro Region of northern Tanzania. Pathogens & Global Health, 110(3), 108-112. doi: 10.1080/20477724.2016.1182719

Zhang, H. L., Omondi, M. W., Musyoka, A. M., Afwamba, I. A., Swai, R. P., Karia, F. P., … Crump, J. A., & Rubach, M. P. (2016). Challenges of maintaining good clinical laboratory practices in low-resource settings: A health program evaluation framework case study from East Africa. American Journal of Clinical Pathology, 146(2), 199-206. doi: 10.1093/ajcp/aqw083

Dittrich, S., Tadesse, B. T., Moussy, F., Chua, A., Zorzet, A., Tängdén, T., … Crump, J. A., … González, I. J. (2016). Target product profile for a diagnostic assay to differentiate between bacterial and non-bacterial infections and reduce antimicrobial overuse in resource-limited settings: An expert consensus. PLoS ONE, 11(8), e0161721. doi: 10.1371/journal.pone.0161721

Aung, H. L., Tun, T., Permina, E., Nyunt, W. W., Aung, S. T., Thinn, K. K., Crump, J. A., & Cook, G. M. (2016). Draft genome sequences of two drug-resistant Mycobacterium tuberculosis isolates from Myanmar. Genome Announcements, 4(5), e00850-16. doi: 10.1128/genomeA.00850-16

Maze, M. J., Biggs, H. M., Rubach, M. P., Galloway, R. L., Cash-Goldwasser, S., Allan, K. J., & Crump, J. A. (2016). Comparison of the estimated incidence of acute leptospirosis in the Kilimanjaro region of Tanzania between 2007-08 and 2012-14. PLoS Neglected Tropical Diseases, 10(12), e0005165. doi: 10.1371/journal.pntd.0005165

Sowerby, S. J., Crump, J. A., Johnstone, M. C., Krause, K. L., & Hill, P. C. (2016). Smartphone microscopy of parasite eggs accumulated into a single field of view. American Journal of Tropical Medicine & Hygiene, 94(1), 227-230. doi: 10.4269/ajtmh.15-0427

von Kalckreuth, V., Konings, F., Aaby, P., Adu-Sarkodie, Y., Ali, M., Aseffa, A., … Crump, J. A., … Marks, F. (2016). The Typhoid Fever Surveillance in Africa Program (TSAP): Clinical, diagnostic, and epidemiological methodologies. Clinical Infectious Diseases, 62(Suppl. 1), S9-S16. doi: 10.1093/cid/civ693

Liu, J., Ochieng, C., Wiersma, S., Ströher, U., Towner, J. S., Whitmer, S., … Crump, J. A., … Fields, B. (2016). Development of a TaqMan Array Card for acute febrile illness outbreak investigation and surveillance of emerging pathogens, including Ebola virus. Journal of Clinical Microbiology, 54(1), 49-58. doi: 10.1128/jcm.02257-15

Hart, P. J., O'Shaughnessy, C. M., Siggins, M. K., Bobat, S., Kingsley, R. A., Goulding, D. A., Crump, J. A., … MacLennan, C. A. (2016). Differential killing of Salmonella enterica serovar Typhi by antibodies targeting Vi and Lipopolysaccharide O:9 antigen. PLoS ONE, 11(1), e0145945. doi: 10.1371/journal.pone.0145945

Global Burden of Disease Pediatrics Collaboration, including Crump, J. A. (2016). Global and national burden of diseases and injuries among children and adolescents between 1990 and 2013: Findings from the Global Burden of Disease 2013 Study. JAMA Pediatrics, 170(3), 267-287. doi: 10.1001/jamapediatrics.2015.4276

Panzner, U., Pak, G. D., Aaby, P., Adu-Sarkodie, Y., Ali, M., Aseffa, A., … Crump, J. A., … Marks, F. (2016). Utilization of healthcare in the Typhoid Fever Surveillance in Africa Program. Clinical Infectious Diseases, 62(Suppl. 1), S56-S68. doi: 10.1093/cid/civ891

Park, S. E., Pak, G. D., Aaby, P., Adu-Sarkodie, Y., Ali, M., Aseffa, A., … Crump, J. A., … Marks, F. (2016). The relationship between invasive nontyphoidal Salmonella disease, other bacterial bloodstream infections, and malaria in Sub-Saharan Africa. Clinical Infectious Diseases, 62(Suppl. 1), S23-S31. doi: 10.1093/cid/civ893

Al-Emran, H. M., Krumkamp, R., Dekker, D. M., Eibach, D., Aaby, P., Adu-Sarkodie, Y., … Crump, J. A., … Marks, F. (2016). Validation and identification of invasive Salmonella serotypes in Sub-Saharan Africa by multiplex polymerase chain reaction. Clinical Infectious Diseases, 62(Suppl. 1), S80-S82. doi: 10.1093/cid/civ782

Al-Emran, H. M., Eibach, D., Krumkamp, R., Ali, M., Baker, S., Biggs, H. M., … Crump, J. A., … Marks, F. (2016). A multicountry molecular analysis of Salmonella enterica serovar typhi with reduced susceptibility to ciprofloxacin in Sub-Saharan Africa. Clinical Infectious Diseases, 62(Suppl. 1), S42-S46. doi: 10.1093/cid/civ788

Aung, H. L., Tun, T., Moradigaravand, D., Köser, C. U., Nyunt, W. W., Aung, S. T., … Crump, J. A., … Cook, G. M., & Hill, P. C. (2016). Whole-genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates from Myanmar. Journal of Global Antimicrobial Resistance, 6, 113-117. doi: 10.1016/j.jgar.2016.04.008

Halliday, J. E. B., Allan, K. J., Ekwem, D., Cleaveland, S., Kazwala, R. R., & Crump, J. A. (2015). Endemic zoonoses in the tropics: A public health problem hiding in plain sight. Veterinary Record, 176(9), 220-225. doi: 10.1136/vr.h798

Prasad, N., Murdoch, D. R., Reyburn, H., & Crump, J. A. (2015). Etiology of severe febrile illness in low- and middle-income countries: A systematic review. PLoS ONE, 10(6), e0127962. doi: 10.1371/journal.pone.0127962

Mavura, D. R., Masenga, E. J., Minja, E., Grossmann, H., Crump, J. A., & Bartlett, J. A. (2015). Initiation of antiretroviral therapy in HIV-infected adults with skin complaints in northern Tanzania. International Journal of Dermatology, 54(1), 68-73. doi: 10.1111/ijd.12563

Penno, E. C., Baird, S. J., & Crump, J. A. (2015). Cost-effectiveness of surveillance for bloodstream infections for sepsis management in low-resource settings. American Journal of Tropical Medicine & Hygiene, 93(4), 850-860. doi: 10.4269/ajtmh.15-0083

Crump, J. A., Wu, X., Kendall, M. A., Ive, P. D., Kumwenda, J. J., Grinsztejn, B., … Swindells, S. (2015). Predictors and outcomes of Mycobacterium tuberculosis bacterium among patients with HIV and tuberculosis co-infection enrolled in the ACTG A5221 STRIDE study. BMC Infectious Diseases, 15, 12. doi: 10.1186/s12879-014-0735-5

GBD 2013 Mortality and Causes of Death Collaborators, including Crump, J. A., & Poulton, R. G. (2015). Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013. Lancet, 385(9963), 117-171. doi: 10.1016/S0140-6736(14)61682-2

Sjölund-Karlsson, M., Howie, R., Rickert, R., Newton, A., Gonzalez-Aviles, G., & Crump, J. A. (2015). Plasmid-mediated quinolone resistance in isolates of Salmonella enterica serotype Typhi, USA. International Journal of Antimicrobial Agents, 45(1), 88-90. doi: 10.1016/j.ijantimicag.2014.09.015

Crump, J. A., Sjölund-Karlsson, M., Gordon, M. A., & Parry, C. M. (2015). Epidemiology, clinical presentation, laboratory diagnosis, antimicrobial resistance, and antimicrobial management of invasive Salmonella infections. Clinical Microbiology Reviews, 28(4), 901-937. doi: 10.1128/cmr.00002-15

Penno, E. C., Crump, J. A., & Baird, S. J. (2015). Performance requirements to achieve cost-effectiveness of point-of-care tests for sepsis among patients with febrile illness in low-resource settings. American Journal of Tropical Medicine & Hygiene, 93(4), 841-849. doi: 10.4269/ajtmh.15-0082

Buchanan, A. M., Fiorillo, S. P., Omondi, M. W., Cunningham, C. K., & Crump, J. A. (2015). Establishment of biochemistry reference values for healthy Tanzanian infants, children, and adolescents in Kilimanjaro Region. Tropical Medicine & International Health, 20(11), 1569-1577. doi: 10.1111/tmi.12580

Global Burden of Disease Study 2013 Collaborators, including Bhala, N., Crump, J. A., Poulton, R. G., & Derrett, S. (2015). Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013. Lancet, 386(9995), 743-800. doi: 10.1016/S0140-6736(15)60692-4

Allan, K. J., Biggs, H. M., Halliday, J. E. B., Kazwala, R. R., Maro, V. P., Cleaveland, S., & Crump, J. A. (2015). Epidemiology of leptospirosis in Africa: A systematic review of a neglected zoonosis and a paradigm for 'One Health' in Africa. PLoS Neglected Tropical Diseases, 9(9), e0003899. doi: 10.1371/journal.pntd.0003899

Nichols, C., Cruz Espinoza, L. M., von Kalckreuth, V., Aaby, P., El Tayeb, M. A., Ali, M., … Crump, J. A., … Marks, F. (2015). Bloodstream infections and frequency of pretreatment associated with age and hospitalization status in sub-Saharan Africa. Clinical Infectious Diseases, 61(Suppl. 4), S372-S379. doi: 10.1093/cid/civ730

Beardsley, J., Denning, D. W., Chau, N. V., Yen, N. T. B., Crump, J. A., & Day, J. N. (2015). Estimating the burden of fungal disease in Vietnam. Mycoses, 58(Suppl. 5), 101-106. doi: 10.1111/myc.12382

Kirk, M. D., Pires, S. M., Black, R. E., Caipo, M., Crump, J. A., Deveesschauwer, B., … Angulo, F. J. (2015). World Health Organization estimates of the global and regional disease burden of 22 foodborne bacterial, protozoal, and viral diseases, 2010: A data synthesis. PLoS Medicine, 12(12), e1001921. doi: 10.1371/journal.pmed.1001921

Rubach, M. P., Maro, V. P., Bartlett, J. A., & Crump, J. A. (2015). Etiologies of illness among patients meeting Integrated Management of Adolescent and Adult Illness District Clinician Manual criteria for severe infections in Northern Tanzania: Implications for empiric antimicrobial therapy. American Journal of Tropical Medicine & Hygiene, 92(2), 454-462. doi: 10.4269/ajtmh.14-0496

Prasad, N., Sharples, K. J., Murdoch, D. R., & Crump, J. A. (2015). Community prevalence of fever and relationship with malaria among infants and children in low-resource areas. American Journal of Tropical Medicine & Hygiene, 93(1), 178-180. doi: 10.4269/ajtmh.14-0646

Wong, V. K., Baker, S., Pickard, D. J., Parkhill, J., Page, A. J., Feasey, N. A., … Crump, J. A., … Dougan, G. (2015). Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events. Nature Genetics, 47(6), 632-639. doi: 10.1038/ng.3281

Ao, T. T., Feasey, N. A., Gordon, M. A., Keddy, K. H., Angulo, F. J., & Crump, J. A. (2015). Global burden of invasive nontyphoidal Salmonella Disease, 2010. Emerging Infectious Diseases, 21(6), 941-949. doi: 10.3201/eid2106.140999

Kumarasamy, N., Aga, E., Ribaudo, H. J., Wallis, C. L., Katzenstein, D. A., Stevens, W. S., … Crump, J. A., … Bartlett, J. A. (2015). Lopinavir/ritonavir monotherapy as second-line antiretroviral treatment in resource-limited settings: Week 104 analysis of AIDS Clinical Trial Group (ACTG) A5230. Clinical Infectious Diseases, 60(10), 1552-1558. doi: 10.1093/cid/civ109

GBD 2013 DALYs, and HALE Collaborators, including Bhala, N., Crump, J. A., Derrett, S., & Poulton, R. G. (2015). Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthly life expectancy (HALE) for 188 countries, 1990-2013: Quantifying the epidemiological transition. Lancet, 386(10009), 2145-2191. doi: 10.1016/ S0140-6736(15)61476-3

Biggs, H. M., Lester, R., Nadjm, B., Mtove, G., Todd, J. E., Kinabo, G. D., … Crump, J. A. (2014). Invasive Salmonella infections in areas of high and low malaria transmission intensity in Tanzania. Clinical Infectious Diseases, 58(5), 638-647. doi: 10.1093/cid/cit798

Moon, A. M., Biggs, H. M., Rubach, M. P., Crump, J. A., Maro, V. P., Saganda, W., & Reddy, E. A. (2014). Evaluation of in-hospital management for febrile illness in Northern Tanzania before and after 2010 World Health Organization Guidelines for the Treatment of Malaria. PLoS ONE, 9(2), e89814. doi: 10.1371/journal.pone.0089814

Vanderburg, S., Rubach, M. P., Halliday, J. E. B., Cleaveland, S., Reddy, E. A., & Crump, J. A. (2014). Epidemiology of Coxiella burnetii Infection in Africa: A OneHealth systematic review. PLoS Neglected Tropical Diseases, 8(4), e2787. doi: 10.1371/journal.pntd.0002787

Naccache, S. N., Federman, S., Veeraraghavan, N., Zaharia, M., Lee, D., Samayoa, E., … Crump, J. A., … Chiu, C. Y. (2014). A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples. Genome Research, 24, 1180-1192. doi: 10.1101/gr.171934.113

Sjölund-Karlsson, M., Howie, R. L., Crump, J. A., & Whichard, J. M. (2014). Fluoroquinolone susceptibility testing of Salmonella enterica: Detection of acquired resistance and selection of zone diameter breakpoints for levofloxacin and ofloxacin. Journal of Clinical Microbiology, 52(3), 877-884. doi: 10.1128/jcm.02679-13

Reddy, E. A., Njau, B. N., Morpeth, S. C., Lancaster, K. E., Tribble, A. C., Maro, V. P., … Crump, J. A., … Hamilton, C. D. (2014). A randomized controlled trial of standard versus intensified tuberculosis diagnostics on treatment decisions by physicians in Northern Tanzania. BMC Infectious Diseases, 14, 89. doi: 10.1186/1471-2334-14-89

Thompson, C. N., Kama, M., Acharya, S., Bera, U., Clemens, J., Crump, J. A., … Mulholland, K. (2014). Typhoid fever in Fiji: A reversible plague? Tropical Medicine & International Health, 19(10), 1284-1292. doi: 10.1111/tmi.12367

Myat, T. O., Prasad, N., Thinn, K. K., Win, K. K., Htike, W. W., Zin, K. N., Murdoch, D. R., & Crump, J. A. (2014). Bloodstream infections at a tertiary referral hospital in Yangon, Myanmar. Transactions of the Royal Society of Tropical Medicine and Hygiene, 108(11), 692-698. doi: 10.1093/trstmh/tru151

Crump, J. A., & Heyderman, R. S. (2014). Invasive Salmonella infections in Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene, 108(11), 673-675. doi: 10.1093/trstmh/tru152

Biggs, H. M., Galloway, R. L., Bui, D. M., Morrissey, A. B., Maro, V. P., & Crump, J. A. (2013). Leptospirosis and human immunodeficiency virus co-infection among febrile inpatients in northern Tanzania. Vector-Borne & Zoonotic Diseases, 13(8), 572-580. doi: 10.1089/vbz.2012.1205

Hertz, J. T., Munishi, O. M., Sharp, J. P., Reddy, E. A., & Crump, J. A. (2013). Comparing actual and perceived causes of fever among community members in a low malaria transmission setting in northern Tanzania. Tropical Medicine & International Health, 18(11), 1406-1415. doi: 10.1111/tmi.12191

Biggs, H. M., Hertz, J. T., Munishi, O. M., Galloway, R. L., Marks, F., Saganda, W., … Crump, J. A. (2013). Estimating leptospirosis incidence using hospital-based surveillance and a population-based health care utilization survey in Tanzania. PLoS Neglected Tropical Diseases, 7(12), e2589. doi: 10.1371/journal.pntd.0002589

Gray, K. D., Cunningham, C. K., Clifton, D. C., Afwamba, I. A., Mushi, G. S., Msuya, L. J., Crump, J. A., & Buchanan, A. M. (2013). Prevalence of mycobacteremia among HIV-infected infants and children in northern Tanzania. Pediatric Infectious Disease Journal, 32(7), 754-756. doi: 10.1097/INF.0b013e318286957f

Fiorillo, S. P., Diefenthal, H. C., Goodman, P. C., Ramadhani, H. O., Njau, B. N., Morrissey, A. B., … Crump, J. A. (2013). Chest radiography for predicting the cause of febrile illness among inpatients in Moshi, Tanzania. Clinical Radiology, 68(10), 1039-1046. doi: 10.1016/j.crad.2013.05.002

Crump, J. A., Morrissey, A. B., Nicholson, W. L., Massung, R. F., Stoddard, R. A., Galloway, R. L., … Bartlett, J. A. (2013). Etiology of severe non-malaria febrile illness in Northern Tanzania: A prospective cohort study. PLoS Neglected Tropical Diseases, 7(7), e2324. doi: 10.1371/journal.pntd.0002324

Rubach, M. P., Halliday, J. E. B., Cleaveland, S., & Crump, J. A. (2013). Brucellosis in low-income and middle-income countries. Current Opinion in Infectious Disease, 26, 404-412. doi: 10.1097/QCO.0b013e3283638104

Crump, J. A., Tuohy, M. J., Morrissey, A. B., Ramadhani, H. O., Njau, B. N., Maro, V. P., … Procop, G. W. (2012). Performance of nucleic acid amplification following extraction of 5 milliliters of whole blood for diagnosis of Mycobacterium tuberculosis bacteremia. Journal of Clinical Microbiology, 50(1), 138-141. doi: 10.1128/jcm.05963-11

Bonsignori, M., Montefiori, D. C., Wu, X., Chen, X., Hwang, K.-K., Tsao, C.-Y., … Crump, J. A., … Haynes, B. F. (2012). Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: Implications for vaccine design. Journal of Virology, 86(8), 4688-4692. doi: 10.1128/jvi.07163-11

Bartlett, J. A., Ribaudo, H. J., Wallis, C. L., Aga, E., Katzenstein, D. A., Stevens, W. S., … Crump, J. A., … Kumarasamy, N. (2012). Lopinavir/ritonavir monotherapy after virologic failure of first-line antiretroviral therapy in resource-limited settings. AIDS, 26(11), 1345-1353. doi: 10.1097/QAD.0b013e328353b066

Hertz, J. T., Munishi, O. M., Ooi, E. E., Howe, S., Lim, W. Y., Chow, A., … Crump, J. A. (2012). Chikungunya and Dengue fever among hospitalized febrile patients in Northern Tanzania. American Journal of Tropical Medicine & Hygiene, 86(1), 171-177. doi: 10.4269/ajtmh.2012.11-0393

Fiorillo, S. P., Landman, K. Z., Tribble, A. C., Mtalo, A., Itemba, D. K., Ostermann, J., … Crump, J. A. (2012). Changes in HIV risk behavior and seroincidence among clients presenting for repeat HIV counseling and testing in Moshi, Tanzania. AIDS Care, 24(10), 1264-1271. doi: 10.1080/09540121.2012.658751

Freel, S. A., Picking, R. A., Ferrari, G., Ding, H., Ochsenbauer, C., Kappes, J. C., … Crump, J. A., … Tomaras, G. D. (2012). Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication. Journal of Virology, 86(12), 6835-6846. doi: 10.1128/jvi.00437-12

Bouley, A. J., Biggs, H. M., Stoddard, R. A., Morrissey, A. B., Bartlett, J. A., Afwamba, I. A., … Crump, J. A. (2012). Brucellosis among hospitalized febrile patients in northern Tanzania. American Journal of Tropical Medicine & Hygiene, 87(6), 1105-1111. doi: 10.4269/ajtmh.2012.12-0327

Jennings, C., Harty, B., Granger, S., Wager, C., Crump, J. A., Fiscus, S. A., & Bremer, J. W. (2012). Cross-platform analysis of HIV-1 RNA data generated by a multicenter assay validation study with wide geographic representation. Journal of Clinical Microbiology, 50(8), 2737-2747. doi: 10.1128/jcm.00578-12

Crump, J. A., Ramadhani, H. O., Morrissey, A. B., Saganda, W., Mwako, M. S., Yang, L.-Y., … Bartlett, J. A. (2012). Bacteremic disseminated tuberculosis in sub-Saharan Africa: A prospective cohort study. Clinical Infectious Diseases, 55(2), 242-250. doi: 10.1093/cid/cis409

Clifton, D. C., Ramadhani, H. O., Msuya, L. J., Njau, B. N., Kinabo, G. D., Buchanan, A. M., & Crump, J. A. (2012). Predicting mortality for paediatric inpatients where malaria is uncommon. Archives of Disease in Childhood, 97(10), 889-894. doi: 10.1136/archdischild-2012-301812

Buchanan, A. M., Nadjm, B., Amos, B., Mtove, G., Sifuna, D., Cunningham, C. K., Crump, J. A., & Reyburn, H. (2012). Utility of rapid antibody tests to exclude HIV-1 infection among infants and children aged <18 months in a low-resource setting. Journal of Clinical Virology, 55(3), 244-249. doi: 10.1016/j.jcv.2012.08.001

Wu, X., Zhou, T., Zhu, J., Zhang, B., Georgiev, I., Wang, C., … Crump, J. A., … Mascola, J. R. (2011). Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science, 333(6049), 1593-1602. doi: 10.1126/science.1207532

McLellan, J. S., Pancera, M., Carrico, C., Gorman, J., Julien, J.-P., Khayat, R., … Crump, J. A., … Kwong, P. D. (2011). Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480(7377), 336-343. doi: 10.1038/nature10696

Ostermann, J., Reddy, E. A., Shorter, M. M., Muiruri, C., Mtalo, A., Itemba, D. K., … Crump, J. A., & Thielman, N. M. (2011). Who tests, who doesn't, and why? Uptake of mobile HIV counseling and testing in the Kilimanjaro Region of Tanzania. PLoS ONE, 6(1), e16488. doi: 10.1371/journal.pone.0016488

Prabhu, M., Nicholson, W. L., Roche, A. J., Kersh, G. J., Fitzpatrick, K. A., Oliver, L. D., … Crump, J. A. (2011). Q fever, spotted fever group, and typhus group rickettsioses among hospitalized febrile patients in Northern Tanzania. Clinical Infectious Diseases, 53(4), e8-e15. doi: 10.1093/cid/cir411

Tomaras, G. D., Binley, J. M., Gray, E. S., Crooks, E. T., Osawa, K., Moore, P. L., … Crump, J. A., … Morris, L. (2011). Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals. Journal of Virology, 85(21), 11502-11519. doi: 10.1128/jvi.05363-11

van Ingen, J., Tortoli, E., Selvarangan, R., Coyle, M. B., Crump, J. A., Morrissey, A. B., … van Soolingen, D. (2011). Mycobacterium sherrisii sp. nov., a slow-growing non-chromogenic species. International Journal of Systematic & Evolutionary Microbiology, 61(6), 1293-1298. doi: 10.1099/ijs.0.024752-0

Waters, R. C., Ostermann, J., Reeves, T. D., Masnick, M. F., Thielman, N. M., Bartlett, J. A., & Crump, J. A. (2011). A cost-effectiveness analysis of alternative HIV retesting strategies in sub-Saharan Africa. Journal of Acquired Immune Deficiency Syndromes, 56(5), 443-452. doi: 10.1097/QAI.0b013e3182118f8c

Keddy, K. H., Sooka, A., Letsoalo, M. E., Hoyland, G., Chaignat, C. L., Morrissey, A. B., & Crump, J. A. (2011). Sensitivity and specificity of typhoid fever rapid antibody tests for laboratory diagnosis at two sub-Saharan African sites. Bulletin of the World Health Organization, 89(9), 640-647. doi: 10.2471/blt.11.087627

Crump, J. A., Ramadhani, H. O., Morrissey, A. B., Msuya, L. J., Yang, L.-Y., Chow, S.-C., … Kinabo, G. D. (2011). Invasive bacterial and fungal infections among hospitalized HIV-infected and HIV-uninfected children and infants in northern Tanzania. Tropical Medicine & International Health, 16(7), 830-837. doi: 10.1111/j.1365-3156.2011.02774.x

Crump, J. A., Morrissey, A. B., Ramadhani, H. O., Njau, B., Maro, V. P., & Reller, L. B. (2011). Controlled comparison of BacT/Alert MB system, manual Myco/F Lytic procedure, and Isolator 10 system for diagnosis of Mycobacterium tuberculosis bacteremia. Journal of Clinical Microbiology, 49(8), 3054-3057. doi: 10.1128/jcm.01035-11

Crump, J. A., Medalla, F. M., Joyce, K. W., Krueger, A. L., Hoekstra, R. M., Whichard, J. M., … and the Emerging Infections Program NARMS Working Groups. (2011). Antimicrobial resistance among invasive nontyphoidal Salmonella enterica isolates in the United States: National Antimicrobial Resistance Monitoring System, 1996 to 2007. Antimicrobial Agents & Chemotherapy, 55(3), 1148-1154. doi: 10.1128/aac.01333-10

Bonsignori, M., Hwang, K.-K., Chen, X., Tsao, C.-Y., Morris, L., Gray, E., … Crump, J. A., … Haynes, B. F. (2011). Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors. Journal of Virology, 85(19), 9998-10009. doi: 10.1128/jvi.05045-11

Biggs, H. M., Bui, D. M., Galloway, R. L., Stoddard, R. A., Shadomy, S. V., Morrissey, A. B., … Crump, J. A. (2011). Leptospirosis among hospitalized febrile patients in northern Tanzania. American Journal of Tropical Medicine & Hygiene, 85(2), 275-281. doi: 10.4269/ajtmh.2011.11-0176

Scott, L. E., Crump, J. A., Msuya, E., Morrissey, A. B., Venter, W. F., & Stevens, W. S. (2011). Abbott RealTime HIV-1 m2000rt viral load testing: Manual extraction versus the automated m2000sp extraction. Journal of Virological Methods, 172(1-2), 78-80. doi: 10.1016/j.jviromet.2010.12.006

Sjölund-Karlsson, M., Joyce, K., Blickenstaff, K., Ball, T., Haro, J., Medalla, F. M., … Crump, J. A., & Whichard, J. M. (2011). Antimicrobial susceptibility to azithromycin among Salmonella enterica isolates from the United States. Antimicrobial Agents & Chemotherapy, 55(9), 3985-3989. doi: 10.1128/aac.00590-11

Prabhu, M., Mchome, B., Ostermann, J., Itemba, D., Njau, B., Thielman, N., KIWAKKUKI-Duke VCT Study Group, including Crump, J. A. (2011). Prevalence and correlates of intimate partner violence among women attending HIV voluntary counseling and testing in northern Tanzania, 2005-2008. International Journal of Gynecology & Obstetrics, 113(1), 63-67. doi: 10.1016/j.ijgo.2010.10.019

Crump, J. A., Ramadhani, H. O., Morrissey, A. B., Saganda, W., Mwako, M. S., Yang, L.-Y., … Maro, V. P. (2011). Invasive bacterial and fungal infections among hospitalized HIV-infected and HIV-uninfected adults and adolescents in northern Tanzania. Clinical Infectious Diseases, 52(3), 341-348. doi: 10.1093/cid/ciq103

Crump, J. A., & Mintz, E. D. (2010). Global trends in typhoid and paratyphoid fever [Invited article]. Clinical Infectious Diseases, 50(2), 241-246. doi: 10.1086/649541

Reddy, E. A., Shaw, A. V., & Crump, J. A. (2010). Community-acquired bloodstream infections in Africa: A systematic review and meta-analysis. Lancet Infectious Diseases, 10(6), 417-432. doi: 10.1016/s1473-3099(10)70072-4

Crump, J. A., Sugarman, J., and the Working Group on Ethics Guidelines for Global Health Training (WEIGHT). (2010). Ethics and best practice guidelines for training experiences in global health. American Journal of Tropical Medicine & Hygiene, 83(6), 1178-1182. doi: 10.4269/ajtmh.2010.10-0527

Emmett, S. D., Cunningham, C. K., Mmbaga, B. T., Kinabo, G. D., Schimana, W., Swai, M. E., … Crump, J. A., & Reddy, E. A. (2010). Predicting virologic failure among HIV-1-infected children receiving antiretroviral therapy in Tanzania: A cross-sectional study. Journal of Acquired Immune Deficiency Syndromes, 54(4), 368-375. doi: 10.1097/QAI.0b013e3181cf4882

Nadjm, B., Amos, B., Mtove, G., Ostermann, J., Chonya, S., Wangai, H., … Crump, J. A., … Reyburn, H. (2010). WHO guidelines for antimicrobial treatment in children admitted to hospital in an area of intense Plasmodium falciparum transmission: Prospective study. BMJ, 340, c1350. doi: 10.1136/bmj.c1350

DuBois, A. E., Crump, J. A., Keswick, B. H., Slutsker, L., Quick, R. E., Vulule, J. M., & Luby, S. P. (2010). Determinants of use of household-level water chlorination products in rural Kenya, 2003-2005. International Journal of Environmental Research & Public Health, 7(10), 3842-3852. doi: 10.3390/ijerph7103842

Buchanan, A. M., Muro, F. J., Gratz, J., Crump, J. A., Musyoka, A. M., Sichangi, M. W., … Cunningham, C. K. (2010). Establishment of haematological and immunological reference values for healthy Tanzanian children in Kilimanjaro Region. Tropical Medicine & International Health, 15(9), 1011-1021. doi: 10.1111/j.1365-3156.2010.02585.x

Shao, H. J., Crump, J. A., Ramadhani, H. O., Uiso, L. O., Ole-Nguyaine, S., Moon, A. M., … Thielman, N. M. (2009). Early versus delayed fixed dose combination abacavir/lamivudine/zidovudine in patients with HIV and tuberculosis in Tanzania. AIDS Research & Human Retroviruses, 25(12), 1277-1285. doi: 10.1089/aid.2009.0100

Morpeth, S. C., Ramadhani, H. O., & Crump, J. A. (2009). Invasive non-Typhi Salmonella disease in Africa. Clinical Infectious Diseases, 49(4), 606-611. doi: 10.1086/603553

Lofgren, S. M., Morrissey, A. B., Chevallier, C. C., Malabeja, A. I., Edmonds, S., Amos, B., … Crump, J. A. (2009). Evaluation of a dried blood spot HIV-1 RNA program for early infant diagnosis and viral load monitoring at rural and remote healthcare facilities. AIDS, 23(18), 2459-2466. doi: 10.1097/QAD.0b013e328331f702

Tribble, A. C., Hamilton, C. D., Crump, J. A., Mgonja, A., Mtalo, A., Ndanu, E., … Thielman, N. M. (2009). Missed opportunities for diagnosis of tuberculosis and human immunodeficiency virus co-infection in Moshi, Tanzania. International Journal of Tuberculosis & Lung Disease, 13(10), 1260-1266.

Tillekeratne, L. G., Thielman, N. M., Kiwera, R. A., Chu, H. Y., Kaale, L., Morpeth, S. C., … Crump, J. A. (2009). Morbidity and mortality among a cohort of HIV-infected adults in a programme for community home-based care, in the Kilimanjaro Region of Tanzania (2003-2005). Annals of Tropical Medicine & Parasitology, 103(3), 263-273. doi: 10.1179/136485909x398203

Shorter, M. M., Ostermann, J., Crump, J. A., Tribble, A. C., Itemba, D. K., Mgonja, A., … Thielman, N. M. (2009). Characteristics of HIV voluntary counseling and testing clients before and during care and treatment scale-up in Moshi, Tanzania. Journal of Acquired Immune Deficiency Syndromes, 52(5), 648-654. doi: 10.1097/QAI.0b013e3181b31a6a

Johnson, O. O., Benjamin, D. K., Benjamin, D. K., Jr, Schimana, W., Tillekeratne, L. G., Crump, J. A., … Cunningham, C. K. (2009). Total lymphocyte count and World Health Organization pediatric clinical stage as markers to assess need to initiate antiretroviral therapy among human immunodeficiency virus-infected children in Moshi, Northern Tanzania. Pediatric Infectious Disease Journal, 28(6), 493-497. doi: 10.1097/INF.0b013e3181950b7f

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