2024
- Shearer HL, Currie MJ, Agnew HN, Trappetti C, Stull F, Pace PE, Paton JC, Dobson RCJ, Dickerhof N, Hypothiocyanous acid reductase is critical for host colonization and infection by Streptococcus pneumoniae. J Biol Chem., In print, 2024
- Swaminathan, A., G.M. Borichevsky, C.M. Frampton, A.S. Day, M.B. Hampton, A.J. Kettle, and R.B. Gearry, Comparison of Fecal Calprotectin and Myeloperoxidase in Predicting Outcomes in Inflammatory Bowel Disease. Inflamm Bowel Dis. DOI: 10.1093/ibd/izae032, 2024
- Fletcher, B.D., J.J. Haszard, M.C.M. Vissers, and T.S. Conner, Smartphone survey data reveal the timecourse of changes in mood outcomes following vitamin C or kiwifruit intervention in adults with low vitamin C. Br J Nutr. 131(8): p. 1384-1396. DOI: 10.1017/s0007114523002787, 2024
- Coker, S.J., M.J. Berry, M.C.M. Vissers, and R.M. Dyson, Maternal Vitamin C Intake during Pregnancy Influences Long-Term Offspring Growth with Timing- and Sex-Specific Effects in Guinea Pigs. Nutrients. 16(3). DOI: 10.3390/nu16030369, 2024
2023
- Winterbourn, C.C., A.V. Peskin, T. Kleffmann, R. Radi, and P.E. Pace, Carbon dioxide/bicarbonate is required for sensitive inactivation of mammalian glyceraldehyde-3-phosphate dehydrogenase by hydrogen peroxide. Proc Natl Acad Sci U S A. 120(18): p. e2221047120. DOI: 10.1073/pnas.2221047120, 2023
- Swaminathan, A., C.M. Frampton, G.M. Borichevsky, A.J. Kettle, and R.B. Gearry, Response to: Evaluating Discriminative Accuracy of Biomarkers in Relation to Binary Study Outcomes: First Validate, Then Celebrate? J Crohns Colitis. 17(1): p. 147-148. DOI: 10.1093/ecco-jcc/jjac126, 2023
- Shearer, H.L., P.E. Pace, L.M. Smith, P.C. Fineran, A.J. Matthews, A. Camilli, N. Dickerhof, and M.B. Hampton, Identification of Streptococcus pneumoniae genes associated with hypothiocyanous acid tolerance through genome-wide screening. J Bacteriol. 205(10): p. e0020823. DOI: 10.1128/jb.00208-23, 2023
- Shearer, H.L., V.V. Loi, P. Weiland, G. Bange, F. Altegoer, M.B. Hampton, H. Antelmann, and N. Dickerhof, MerA functions as a hypothiocyanous acid reductase and defense mechanism in Staphylococcus aureus. Mol Microbiol. 119(4): p. 456-470. DOI: 10.1111/mmi.15035, 2023
- Seddon, A.R., A.B. Das, M.B. Hampton, and A.J. Stevens, Site-specific decreases in DNA methylation in replicating cells following exposure to oxidative stress. Hum Mol Genet. 32(4): p. 632-648. DOI: 10.1093/hmg/ddac232, 2023
- Praditi, C., S.M. Bozonet, G.U. Dachs, and M.C.M. Vissers, Ascorbate Uptake and Retention by Breast Cancer Cell Lines and the Intracellular Distribution of Sodium-Dependent Vitamin C Transporter 2. Antioxidants (Basel). 12(11). DOI: 10.3390/antiox12111929, 2023
- Peeters, W.M., M. Gram, G.J. Dias, M.C.M. Vissers, M.B. Hampton, N. Dickerhof, A.E. Bekhit, M.J. Black, J. Oxbøll, S. Bayer, M. Dickens, K. Vitzel, P.W. Sheard, K.M. Danielson, L.D. Hodges, J.C. Brønd, J. Bond, B.G. Perry, L. Stoner, J. Cornwall, and D.S. Rowlands, Changes to insulin sensitivity in glucose clearance systems and redox following dietary supplementation with a novel cysteine-rich protein: A pilot randomized controlled trial in humans with type-2 diabetes. Redox Biol. 67: p. 102918. DOI: 10.1016/j.redox.2023.102918, 2023
- Paumann-Page, M., C. Obinger, C.C. Winterbourn, and P.G. Furtmüller, Peroxidasin Inhibition by Phloroglucinol and Other Peroxidase Inhibitors. Antioxidants (Basel). 13(1). DOI: 10.3390/antiox13010023, 2023
- Pace, P.E. and C.C. Winterbourn, Letter to the Editor: A Cautionary Note on Using Phosphatase Inhibitors with Hydrogen Peroxide. Antioxid Redox Signal. 38(4-6): p. 316-317. DOI: 10.1089/ars.2022.0092, 2023
- Kettle, A.J., L.V. Ashby, C.C. Winterbourn, and N. Dickerhof, Superoxide: The enigmatic chemical chameleon in neutrophil biology. Immunol Rev. 314(1): p. 181-196. DOI: 10.1111/imr.13183, 2023
- Hampton, M.B. and N. Dickerhof, Inside the phagosome: A bacterial perspective. Immunol Rev. 314(1): p. 197-209. DOI: 10.1111/imr.13182, 2023
- Coker, S.J., R.M. Dyson, C.C. Smith-Díaz, M.C.M. Vissers, and M.J. Berry, Effects of Low Vitamin C Intake on Fertility Parameters and Pregnancy Outcomes in Guinea Pigs. Nutrients. 15(19). DOI: 10.3390/nu15194107, 2023
- Bozonet, S.M., N.J. Magon, A.J. Schwartfeger, A. Konigstorfer, S.G. Heath, M.C.M. Vissers, V.K. Morris, C. Göbl, J.M. Murphy, G.S. Salvesen, and M.B. Hampton, Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis. J Biol Chem. 299(6): p. 104792. DOI: 10.1016/j.jbc.2023.104792, 2023
2022
- Taylor, M.F., M.A. Black, M.B. Hampton, and E.C. Ledgerwood, Insights into H(2)O(2)-induced signaling in Jurkat cells from analysis of gene expression. Free Radic Res. 56(9-10): p. 666-676. DOI: 10.1080/10715762.2023.2165073, 2022
- Swaminathan, A., G.M. Borichevsky, T.S. Edwards, E. Hirschfeld, T.C. Mules, C.M.A. Frampton, A.S. Day, M.B. Hampton, A.J. Kettle, and R.B. Gearry, Faecal Myeloperoxidase as a Biomarker of Endoscopic Activity in Inflammatory Bowel Disease. J Crohns Colitis. 16(12): p. 1862-1873. DOI: 10.1093/ecco-jcc/jjac098, 2022
- Shearer, H.L., P.E. Pace, J.C. Paton, M.B. Hampton, and N. Dickerhof, A newly identified flavoprotein disulfide reductase Har protects Streptococcus pneumoniae against hypothiocyanous acid. J Biol Chem. 298(9): p. 102359. DOI: 10.1016/j.jbc.2022.102359, 2022
- Murphy, M.P., H. Bayir, V. Belousov, C.J. Chang, K.J.A. Davies, M.J. Davies, T.P. Dick, T. Finkel, H.J. Forman, Y. Janssen-Heininger, D. Gems, V.E. Kagan, B. Kalyanaraman, N.G. Larsson, G.L. Milne, T. Nyström, H.E. Poulsen, R. Radi, H. Van Remmen, P.T. Schumacker, P.J. Thornalley, S. Toyokuni, C.C. Winterbourn, H. Yin, and B. Halliwell, Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo. Nat Metab. 4(6): p. 651-662. DOI: 10.1038/s42255-022-00591-z, 2022
- Edwards, T.S., N. Dickerhof, N.J. Magon, L.N. Paton, P.D. Sly, and A.J. Kettle, Formation of Calprotectin-Derived Peptides in the Airways of Children with Cystic Fibrosis. J Immunol. 208(4): p. 979-990. DOI: 10.4049/jimmunol.2001017, 2022
- Crake, R.L.I., E.R. Burgess, G.A.R. Wiggins, N.J. Magon, A.B. Das, M.C.M. Vissers, H.R. Morrin, J.A. Royds, T.L. Slatter, B.A. Robinson, E. Phillips, and G.U. Dachs, Ascorbate content of clinical glioma tissues is related to tumour grade and to global levels of 5-hydroxymethyl cytosine. Sci Rep. 12(1): p. 14845. DOI: 10.1038/s41598-022-19032-8, 2022
- Conner, T.S., B.D. Fletcher, J.J. Haszard, J.M. Pullar, E. Spencer, L.A. Mainvil, and M.C.M. Vissers, Reply to Vorland et al. Mixed Random and Nonrandom Allocation, and Group Randomization Have Been Mislabeled and Misanalysed, Necessitating Reanalysis. Comment on "Conner et al. KiwiC for Vitality: Results of a Randomized Placebo-Controlled Trial Testing the Effects of Kiwifruit or Vitamin C Tablets on Vitality in Adults with Low Vitamin C Levels. Nutrients 2020, 12, 2898". Nutrients. 14(19). DOI: 10.3390/nu14194065, 2022
- Conner, T.S., B.D. Fletcher, J.J. Haszard, J.M. Pullar, E. Spencer, L.A. Mainvil, and M.C.M. Vissers, Correction: Conner et al. KiwiC for Vitality: Results of a Placebo-Controlled Trial Testing the Effects of Kiwifruit or Vitamin C Tablets on Vitality in Adults with Low Vitamin C Levels. Nutrients 2020, 12, 2898. Nutrients. 14(19). DOI: 10.3390/nu14194063, 2022
- Burgess, E.R., R.L.I. Crake, E. Phillips, H.R. Morrin, J.A. Royds, T.L. Slatter, G.A.R. Wiggins, M.C.M. Vissers, B.A. Robinson, and G.U. Dachs, Increased Ascorbate Content of Glioblastoma Is Associated With a Suppressed Hypoxic Response and Improved Patient Survival. Front Oncol. 12: p. 829524. DOI: 10.3389/fonc.2022.829524, 2022
- Ashby, L.V., R. Springer, V.V. Loi, H. Antelmann, M.B. Hampton, A.J. Kettle, and N. Dickerhof, Oxidation of bacillithiol during killing of Staphylococcus aureus USA300 inside neutrophil phagosomes. J Leukoc Biol. 112(4): p. 591-605. DOI: 10.1002/jlb.4hi1021-538rr, 2022