Dr Mik Black
Senior Lecturer, Department of Biochemistry
Mik received a BSc (Hons) in Statistics from the University of Canterbury, and a MS (Mathematical Statistics) and PhD (Statistics) from Purdue University. After completing his PhD in 2002, Mik returned to New Zealand to work as a Lecturer in the Department of Statistics at The University of Auckland.
An ongoing involvement in a number of Dunedin-based collaborative genomics projects resulted in a move to the University of Otago in 2006. Mik’s research focuses on the development and application of statistical methods for the analysis of data from genomics experiments, with a particular emphasis on colorectal and breast cancer.
Mik is also involved in the provision of grid-based computing tools for the NZ bioscience community via BeSTGRID, and the development of a national genomics infrastructure through New Zealand Genomics Ltd (NZGL).
For more information on Mik: http://biochem.otago.ac.nz/dr-mik-black/
Teaching
Mik teaches microarray modules in BIOC 354 Bioinformatics and Functional Genomics and BIOC 451 Contemporary Technologies in Biochemistry.
Recent Publications
Nasri. S., Anjomshoaa, A., Song, S., Guilford, P., McNoe, L., Black, M., Phillips, V., Reeve, A., Humar, B. Oligonucleotide array outperforms SNP array on formalin-fixed paraffin-embedded clinical samples. Cancer Genetics and Cytogenetics (2010) vol. 198 (1) pp. 1-6.
Ariazi, E.A., Brailoiu E., Yerrum, S., Shupp, H.A., Slifker, M.J., Cunliffe, H.E., Black, M.A., Donato, A.L., Arterburn, J.B., Oprea, T.I., Prossnitz, E.R., Dun, N.J., Jordan, V.C. The G Protein-Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor-Positive Breast Cancer Cells. Cancer Research (2010): Jan 19 [Epub ahead of print].
Wu, S., Black, M.A., North, R.A., Atkinson, K., Rodrigo, A. A novel statistical model to identify biomarkers in 2D-PAGE gels. PLoS Computational Biology, (2009) vol. 5 (9):e1000509.
Kho, E.M., McCowan, L.M., North, R.A., Roberts, C.T., Chan, E., Black, M.A., Taylor, R.S., Dekker, G.A. Duration of Sexual Relationship and Its Effect on Preeclampsia and Small for Gestational Age. Journal of Reproductive Immunology, (2009) vol. 82 (1):66-73.
Anjomshoaa A., Nasri, S., McCall, J.L., Chatterjee, A., Yoon, H-S., McNoe, L, Black, M.A., Reeve, A.E. (2009) Slow proliferation as a biological feature of colorectal cancer metastasis. British Journal of Cancer 101(5):822-8.
Pilbrow., A.P., Ellmers, L.J., Black, M.A., Moravec, C.S., Sweet, W.E., Troughton, R.W., Richards, A.M., Frampton, C.M., Cameron, V.A. (2008) Genomic selection of reference genes for real-time PCR in human myocardium. BMC Med Genomics, 2008:1:64.
Song, S., and Black, M.A. (2008) Microarray-based gene set analysis: a comparison of current methods. BMC Bioinformatics, 9:502-507.
Jacobs, G.H., Chen, A., Stevens, S.G., Stockwell, P.A., Black, M.A., Tate, W.P., Brown, C.M. (2008) Transterm: a database to aid the analysis of regulatory sequences in mRNAs. Nucleic Acids Research, 37:D72-6.
Anjomshoaa, A., Lin, Y.H., Black, M.A., McCall, J.L., Humar, B., Fukuzawa, R., Yoon, H-S., Holzmann, B., Friederichs, J., van Rij, A., Thompson-Fawcett, M. and Reeve, A.E. (2008) Reduced expression of a gene proliferation signature is associated with enhanced malignancy in colon cancer. British Journal of Cancer. 99: 966–973.
John, T., Black, M.A., Toro, T.T., Leader, D., Gedye, C.A., Davis, I.D., Guilford, P.J., Cebon, J.S. (2008) Predicting Clinical Outcome through Molecular Profiling in Stage III Melanoma. Clinical Cancer Research, 14: 5173-5180.
Willis, A.L., Tran, N.L., Chatigny, J.M., Charlton, N., Vu, H., Brown, S.A.N., Black, M.A., McDonough, W.S., Fortin, S.P., Niska, J.R., Winkles, J.A., and Cunliffe, H.E. (2008) The Fibroblast Growth Factor–Inducible 14 Receptor Is Highly Expressed in HER2-Positive Breast Tumors and Regulates Breast Cancer Cell Invasive Capacity. Molecular Cancer Research, 6:725-734.