Dr Christine Jasoni

Senior Lecturer, Anatomy and Structural Biology

Dr Jasoni's lab is interested in understanding the underlying genetic causes of congenital cognitive deficit. Dr Jasoni focuses on identifying genes whose altered expression leads to brain wiring abnormalities during development, and on discovering how this gene expression is changed by genetic and epigenetic mechanisms. With the use of mouse genetic models, including transgenics and cre/loxP cell-type specific deletions, she tests the role of identified genes on brain development and subsequent cognitive behaviours, such as learning and attention.

For more information on Christine's work: http://anatomy.otago.ac.nz/research/devel_neuroendo/index.html

Recent Publications

Jasoni, C.L., Porteous, R.W. & Herbison, A.E. Anatomical Location of Mature GnRH Neurons Corresponds With Their Birthdate in the Developing Mouse. Developmental Dynamics 238, 524-531 (2009).

Romano, N., Lee, K., Abraham, I.M., Jasoni, C.L. & Herbison, A.E. Nonclassical Estrogen Modulation of Presynaptic GABA Terminals Modulates Calcium Dynamics in Gonadotropin-Releasing Hormone Neurons. Endocrinology 149, 5335-5344 (2008).