John McEwan
Senior Scientist, Animal Genomics, AgResearch Invermay
John specialises in sheep and cattle genetics. His current research includes sequencing the sheep genome, creation of high density SNP chips and their use to allow faster genetic improvement in sheep via a technique called whole genome selection.
For more information on John's work: http://www.sheephapmap.org or http://www.agresearch.co.nz/about-us/our-people/
Teaching
John teaches in GENE 311 Genetic Analysis of Eukaryotes.
Recent Publications
Keane OM, Maqbool N, McCulloch AF, McEwan JC, Dodds KG. (2009) Generation of a preliminary bovine gene atlas, using expression clustering to annotate gene function. Genet Mol Res.8(3):1013-27.
Bovine HapMap Consortium. Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science. 2009 Apr 24; 324(5926):528-32.
Bovine Genome Sequencing and Analysis Consortium. The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science. 2009 Apr 24; 324(5926):522-8.
Johnson PL, Dodds KG, Bain WE, Greer GJ, McLean NJ, McLaren RJ, Galloway SM, van Stijn TC, McEwan JC. Investigations into the GDF8 g+6723G-A polymorphism in New Zealand Texel sheep. J Anim Sci. 2009 Jun; 87(6):1856-64. Epub 2009 Feb 27.
Ratnakumar A, Barris W, McWilliam S, Brauning R, McEwan JC, Snelling WM, Dalrymple BP. A multiway analysis for identifying high integrity bovine BACs. BMC Genomics. 2009 Jan 23; 10:46.
MacEachern S, Hayes B, McEwan J, Goddard M. An examination of positive selection and changing effective population size in Angus and Holstein cattle populations (Bos taurus) using a high density SNP genotyping platform and the contribution of ancient polymorphism to genomic diversity in Domestic cattle. BMC Genomics. 2009 Apr 24; 10:181.
MacEachern S, McEwan J, McCulloch A, Mather A, Savin K, Goddard M. Molecular evolution of the Bovini tribe (Bovidae, Bovinae): is there evidence of rapid evolution or reduced selective constraint in Domestic cattle? BMC Genomics. 2009 Apr 24; 10:179.
Maceachern S, McEwan J, Goddard M. Phylogenetic reconstruction and the identification of ancient polymorphism in the Bovini tribe (Bovidae, Bovinae). BMC Genomics. 2009 Apr 24; 10(1):177.
International Sheep Genomics Consortium. A genome wide survey of SNP variation reveals the genetic structure of sheep breeds. PLoS ONE. 2009; 4(3):e4668. Epub 2009 Mar 3.
Keane, O.M., Dodds, K.G., Crawford, A.M. & McEwan, J.C. Identifying Genes for Intestinal Nematode Resistance using Transcriptional Profiling. in International Symposium on Animal Genomics for Animal Health (eds Pinard, M.H., Gay, C., Pastoret, P.P. & Dodet, B.) 205-212 (Paris, FRANCE, 2007).