Professor Ian Morison

Head of the Department of Pathology

Professor Morison's research interests includes childhood acute lymphoblastic leukaemia (epigenetics), epigenetics of development (IVF and placental), genomic imprinting, genetics of blood disorders, and others.

Further information about Ian is available on the Pathology website.

Teaching

GENE 313 Medical Genetics
GENE 412 Current Topics in Genetics

Recent Publications

Online Database “A Catalogue of Parent-of-Origin Effects.” www.otago.ac.nz/IGC
Compiled, edited and maintained by Ian Morison.

Morison IM, Cramer EM, Cheesman EJ, Cheong PL, Holyoake AJ , Fichelson S, Weeks RJ, Lo A, Davies SMK, Wilbanks SM, Fagerlund RD, Ludgate MW, da Silva Tatley FM, Coker MSA, Bockett NA, Hughes G, Pippig DA, Smith MP, Capron C, Ledgerwood EC. A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but only causes thrombocytopenia. Nature Genetics 2008;40:387-389

Krueger C, Morison IM. Random monoallelic expression – making a choice. Trends in Genetics 2008;24:257-259

Fukuzawa R, Anaka AR, Heathcott RW, McNoe LA, Morison IM, Perlman EJ, Reeve AE. Wilms tumour histology is determined by distinct types of precursor lesions and not epigenetic changes. Journal of Pathology 2008;215:377–387

Weeks RJ, Kees UR, Song S, Morison IM. Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia. Molecular Cancer 2010, 9:163

Macaulay EC, Weeks RJ, Andrews S, Morison IM. Hypomethylation of functional retrotransposon-derived genes in the human placenta. Mammalian Genome 2011;22:722-735.

Cramer Bordé EM, Ouzegdouh Y, Ledgerwood EC, Morison IM. Congenital thrombocytopenia and cytochrome c mutation: A matter of birth and death. Seminars in Thrombosis and Hemostasis 2011;37:664-672

Oliver VF, Miles HL, Cutfield WS, Hofman PL, Ludgate JL, Morison IM. Defects in imprinting and genome-wide DNA methylation are not common in the IVF population. Fertility and Sterility, 2012;97:147-153

Rodger EJ, Morison IM. Myelodysplastic Syndrome in New Zealand and Australia. Internal Medicine Journal 2012 in press.

Chatterjee A, Peter A. Stockwell PA, Rodger EJ, Morison IM. Comparison of alignment software for genome-wide bisulphite sequence data. Nucleic Acid Research. In press.