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Health Sciences profile

Christine Barthow

PositionResearch Fellow
DepartmentDepartment of Medicine (UOW)
QualificationsRCompNs, MA(appl)
Research summaryAllergic disease

Research

I am a Registered Nurse and Research Fellow with the Wellington Asthma Research Group. Currently I am a co-investigator in the Maternal Probiotic Study (Studies of Probiotics and Allergic Disease). This is a randomized controlled trial clinical trial investigating the use of probiotics to prevent the development of allergic disease in infants, and reduce gestational diabetes and bacterial vaginal infections in pregnant women.

My current research interest is in the field of allergic disease. In the past four years I have worked on a series of quantitative studies related to both the prevention and treatment of allergic disease (eczema, hay fever and asthma). Previous to this work my research interest and experience was in the area of oncology/palliative care using qualitative approaches to research.

Publications

Wickens, K. L., Barthow, C. A., Murphy, R., Abels, P. R., Maude, R. M., Stone, P. R., … Stanley, T. V., Purdie, G. L., Kang, J. M., Hood, F. E., … Barnes, P. K., … Crane, J. (2017). Early pregnancy probiotic supplementation with Lactobacillus rhamnosus HN001 may reduce the prevalence of gestational diabetes mellitus: A randomised controlled trial. British Journal of Nutrition. Advance online publication. doi: 10.1017/S0007114517000289

Slykerman, R. F., Hood, F., Wickens, K., Thompson, J. M. D., Barthow, C., Murphy, R., Kang, J., … Crane, J., Stanley, T., Abels, P., Purdie, G., … the Probiotic in Pregnancy Study Group. (2017). Effect of Lactobacillus rhamnosus HN001 in pregnancy on postpartum symptoms of depression and anxiety: A randomised double-blind placebo-controlled trial. EBioMedicine. Advance online publication. doi: 10.1016/j.ebiom.2017.09.013

Ballantyne, A., Pullon, S., Macdonald, L., Barthow, C., Wickens, K., & Crane, J. (2017). The experiences of pregnant women in an interventional clinical trial: Research in Pregnancy Ethics (RIPE) study. Bioethics, 31(6), 476-483. doi: 10.1111/bioe.12361

Ballantyne, A., Barthow, C., & Wickens, K. (2016). Research into lifestyle changes in pregnancy. In F. Baylis & A. Ballantyne (Eds.), Clinical research involving pregnant women. (pp. 211-225). Springer. doi: 10.1007/978-3-319-26512-4_12

Barthow, C., Wickens, K., Stanley, T., Mitchell, E. A., Maude, R., Abels, P., Purdie, G., … Kang, J., Hood, F., … Barnes, P., Fitzharris, P., … Crane, J. (2016). The Probiotics in Pregnancy Study (PiP Study): Rationale and design of a double-blind randomised controlled trial to improve maternal health during pregnancy and prevent infant eczema and allergy. BMC Pregnancy & Childbirth, 16(1), 133. doi: 10.1186/s12884-016-0923-y

Chapter in Book - Research

Ballantyne, A., Barthow, C., & Wickens, K. (2016). Research into lifestyle changes in pregnancy. In F. Baylis & A. Ballantyne (Eds.), Clinical research involving pregnant women. (pp. 211-225). Springer. doi: 10.1007/978-3-319-26512-4_12

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Journal - Research Article

Wickens, K. L., Barthow, C. A., Murphy, R., Abels, P. R., Maude, R. M., Stone, P. R., … Stanley, T. V., Purdie, G. L., Kang, J. M., Hood, F. E., … Barnes, P. K., … Crane, J. (2017). Early pregnancy probiotic supplementation with Lactobacillus rhamnosus HN001 may reduce the prevalence of gestational diabetes mellitus: A randomised controlled trial. British Journal of Nutrition. Advance online publication. doi: 10.1017/S0007114517000289

Slykerman, R. F., Hood, F., Wickens, K., Thompson, J. M. D., Barthow, C., Murphy, R., Kang, J., … Crane, J., Stanley, T., Abels, P., Purdie, G., … the Probiotic in Pregnancy Study Group. (2017). Effect of Lactobacillus rhamnosus HN001 in pregnancy on postpartum symptoms of depression and anxiety: A randomised double-blind placebo-controlled trial. EBioMedicine. Advance online publication. doi: 10.1016/j.ebiom.2017.09.013

Ballantyne, A., Pullon, S., Macdonald, L., Barthow, C., Wickens, K., & Crane, J. (2017). The experiences of pregnant women in an interventional clinical trial: Research in Pregnancy Ethics (RIPE) study. Bioethics, 31(6), 476-483. doi: 10.1111/bioe.12361

Marlow, G., Han, D. Y., Wickens, K., Stanley, T., Crane, J., Mitchell, E. A., … Barthow, C., … Morgan, A. R. (2015). Differential effects of two probiotics on the risks of eczema and atopy associated with single nucleotide polymorphisms to Toll-like receptors. Pediatric Allergy & Immunology, 26(3), 262-271. doi: 10.1111/pai.12371

Barthow, C., Jones, B., Macdonald, L., Vernall, S., Gallagher, P., & McKinlay, E. (2015). Researching in the community: The value and contribution of nurses to community based or primary health care research. Primary Health Care Research & Development, 16, 224-234. doi: 10.1017/s1463423614000097

Morgan, A. R., Han, D. Y., Wickens, K., Barthow, C., Mitchell, E. A., Stanley, T. V., Dekker, J., Crane, J., & Ferguson, L. R. (2014). Differential modification of genetic susceptibility to childhood eczema by two probiotics. Clinical & Experimental Allergy, 44(10), 1255-1265. doi: 10.1111/cea.12394

Wickens, K., Stanley, T. V., Mitchell, E. A., Barthow, C., Fitzharris, P., Purdie, G., Siebers, R., … Crane, J. (2013). Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: Does it also reduce atopic sensitization? Clinical & Experimental Allergy, 43(9), 1048-1057. doi: 10.1111/cea.12154

Wickens, K., Black, P., Stanley, T. V., Mitchell, E., Barthow, C., Fitzharris, P., Purdie, G., & Crane, J. (2012). A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years. Clinical & Experimental Allergy, 42(7), 1071-1079. doi: 10.1111/j.1365-2222.2012.03975.x

McCullough, L., McKinlay, E., Barthow, C., Moss, C., & Wise, D. (2010). A model of treatment decision making when patients have advanced cancer: How do cancer treatment doctors and nurses contribute to the process? European Journal of Cancer Care, 19(4), 482-491. doi: 10.1111/j.1365-2354.2009.01074.x

Barthow, C., Moss, C., McKinlay, E., McCullough, L., & Wise, D. (2009). To be involved or not: Factors that influence nurses' involvement in providing treatment decisional support in advanced cancer. European Journal of Oncology Nursing, 13(1), 22-28. doi: 10.1016/j.ejon.2008.09.004

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Journal - Research Other

Barthow, C., Wickens, K., Stanley, T., Mitchell, E. A., Maude, R., Abels, P., Purdie, G., … Kang, J., Hood, F., … Barnes, P., Fitzharris, P., … Crane, J. (2016). The Probiotics in Pregnancy Study (PiP Study): Rationale and design of a double-blind randomised controlled trial to improve maternal health during pregnancy and prevent infant eczema and allergy. BMC Pregnancy & Childbirth, 16(1), 133. doi: 10.1186/s12884-016-0923-y

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