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Pharmacy staff profile

Professor Sarah Hook

PositionAssociate Dean (Research)
QualificationsBSc(Hons) PhD(Otago) ASI APSA
Research summaryVaccine formulation and delivery
TeachingImmunology and infectious diseases to undergraduate and postgraduate students

Research

My area of interest is in the development and testing (physical, chemical and immunological) of novel vaccine formulations for the prevention and treatment of both communicable and non-communicable disease. My specific areas of interest are in the development of one-shot sustained release vaccines and in needle-free (transdermal or oral) vaccines for the treatment of tuberculosis and cancer.

My research focuses on:

  • Sustained release vaccines
  • Needle free vaccines
  • Therapeutic cancer vaccines
  • Identification and formulation of novel adjuvants

Professor Hook on Google Scholar

Publications

Umair, S., Pernthaner, A., Deng, Q., Gibson, B., Hook, S., & Heath, D. (2017). Preliminary evaluation of a thermosensitive chitosan hydrogel for Echinococcus granulosus vaccine delivery. Veterinary Parasitology. Advance online publication. doi: 10.1016/j.vetpar.2017.02.007

Matikonda, S. S., Fairhall, J. M., Tyndall, J. D. A., Hook, S., & Gamble, A. B. (2017). Stability, kinetic, and mechanistic investigation of 1,8-self-immolative cinnamyl ether spacers for controlled release of phenols and generation of resonance and inductively stabilized methides. Organic Letters, 19(3), 528-531. doi: 10.1021/acs.orglett.6b03695

Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2017). Characterization and evaluation of stabilized particulate formulations as therapeutic oral vaccines for allergy. Journal of Liposome Research. Advance online publication. doi: 10.1080/08982104.2017.1370472

Cooper, A., Singh, S., Hook, S., Tyndall, J. D. A., Vernall, A. J., & Alexander, S. P. H. (2017). Chemical tools for studying lipid-binding class A G protein-coupled receptors. Pharmacological Reviews, 69(3), 316-353. doi: 10.1124/pr.116.013243

Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2017). Liposomal α-galactosylceramide is taken up by gut-associated lymphoid tissue and stimulates local and systemic immune responses. Journal of Pharmacy & Pharmacology. Advance online publication. doi: 10.1111/jphp.12814

Edited Book - Research

Foged, C., Rades, T., Perrie, Y., & Hook, S. (Eds.). (2015). Subunit vaccine delivery. New York: Springer. doi: 10.1007/978-1-4939-1417-3

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Chapter in Book - Research

Rattanapak, T., Foged, C., & Hook, S. (2015). Transcutaneous immunization. In C. Foged, T. Rades, Y. Perrie & S. Hook (Eds.), Subunit vaccine delivery. (pp. 347-369). New York: Springer. doi: 10.1007/978-1-4939-1417-3

Buchan, G. S., Lockhart, D., Slobbe, L., Chinn, N., Hook, S., Thomson, A., & Griffin, F. (1995). Vaccination: Can it be improved? In F. Griffin & G. de Lisle (Eds.), Tuberculosis in wildlife and domestic animals. (pp. 116-120). Dunedin: Otago University Press.

Hook, S., Slobbe, L., Chinn, N., Griffin, J. F. T., & Hesketh, J. B. (1995). Measuring cytokine responses to vaccination with live and killed BCG. In F. Griffin & G. de Lisle (Eds.), Tuberculosis in wildlife and domestic animals. (pp. 128-130). Dunedin: Otago University Press.

Lockhart, E., Slobbe, L., Hook, S., Griffin, F., & Mackintosh, C. G. (1995). The development of a new, multipurpose, animal model of tuberculosis. In F. Griffin & G. de Lisle (Eds.), Tuberculosis in wildlife and domestic animals. (pp. 158-160). Dunedin: Otago University Press.

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Journal - Research Article

Umair, S., Pernthaner, A., Deng, Q., Gibson, B., Hook, S., & Heath, D. (2017). Preliminary evaluation of a thermosensitive chitosan hydrogel for Echinococcus granulosus vaccine delivery. Veterinary Parasitology. Advance online publication. doi: 10.1016/j.vetpar.2017.02.007

Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2017). Liposomal α-galactosylceramide is taken up by gut-associated lymphoid tissue and stimulates local and systemic immune responses. Journal of Pharmacy & Pharmacology. Advance online publication. doi: 10.1111/jphp.12814

Cooper, A., Singh, S., Hook, S., Tyndall, J. D. A., Vernall, A. J., & Alexander, S. P. H. (2017). Chemical tools for studying lipid-binding class A G protein-coupled receptors. Pharmacological Reviews, 69(3), 316-353. doi: 10.1124/pr.116.013243

Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2017). Characterization and evaluation of stabilized particulate formulations as therapeutic oral vaccines for allergy. Journal of Liposome Research. Advance online publication. doi: 10.1080/08982104.2017.1370472

Matikonda, S. S., Fairhall, J. M., Tyndall, J. D. A., Hook, S., & Gamble, A. B. (2017). Stability, kinetic, and mechanistic investigation of 1,8-self-immolative cinnamyl ether spacers for controlled release of phenols and generation of resonance and inductively stabilized methides. Organic Letters, 19(3), 528-531. doi: 10.1021/acs.orglett.6b03695

Even, M.-P., Bobbala, S., Gibson, B., Hook, S., Winter, G., & Engert, J. (2017). Twin-screw extruded lipid implants containing TRP2 peptide for tumour therapy. European Journal of Pharmaceutics & Biopharmaceutics, 114, 79-87. doi: 10.1016/j.ejpb.2016.12.033

Gauld, N. J., Braganza, C., Babalola, O. O., Huynh, T. T., & Hook, S. M. (2016). Reasons for use and non-use of the pertussis vaccine during pregnancy: An interview study. Journal of Primary Health Care, 8(4), 344-350. doi: 10.1071/HC15049

Subharat, S., Shu, D., Zheng, T., Buddle, B. M., Kaneko, K., Hook, S., … Wedlock, D. N. (2016). Vaccination of sheep with a methanogen protein provides insight into levels of antibody in saliva needed to target ruminal methanogens. PLoS ONE, 11(7), e0159861. doi: 10.1371/journal.pone.0159861

Neumann, S., Shirley, S. A., Kemp, R. A., & Hook, S. M. (2016). Improved anti-tumor activity of a therapeutic melanoma vaccine through the use of the dual COX-2/5-LO inhibitor licofelone. Frontiers in Immunology, 7(537), 537. doi: 10.3389/fimmu.2016.00537

Bobbala, S., Tamboli, V., McDowell, A., Mitra, A. K., & Hook, S. (2016). Novel injectable pentablock copolymer based thermoresponsive hydrogels for sustained release vaccines. AAPS Journal, 18(1), 261-269. doi: 10.1208/s12248-015-9843-4

Azhari, H., Strauss, M., Hook, S., Boyd, B. J., & Rizwan, S. B. (2016). Stabilising cubosomes with Tween 80 as a step towards targeting lipid nanocarriers to the blood-brain barrier. European Journal of Pharmaceutics & Biopharmaceutics, 104, 148-155. doi: 10.1016/j.ejpb.2016.05.001

Bobbala, S., & Hook, S. (2016). Is there an optimal formulation and delivery strategy for subunit vaccines? Pharmaceutical Research, 33(9), 2078-2097. doi: 10.1007/s11095-016-1979-0

Highton, A. J., Girardin, A., Bell, G. M., Hook, S. M., & Kemp, R. A. (2016). Chitosan gel vaccine protects against tumour growth in an intracaecal mouse model of cancer by modulating systemic immune responses. BMC Immunology, 17, 39. doi: 10.1186/s12865-016-0178-4

Neumann, S., Young, K., Compton, B., Anderson, R., Painter, G., & Hook, S. (2015). Synthetic TRP2 long-peptide and α-galactosylceramide formulated into cationic liposomes elicit CD8+ T-cell responses and prevent tumour progression. Vaccine. doi: 10.1016/j.vaccine.2015.08.083

Greatrex, B. W., Daines, A. M., Hook, S., Lenz, D. H., McBurney, W., Rades, T., & Rendle, P. M. (2015). Synthesis, formulation, and adjuvanticity of monodesmosidic saponins with olenanolic acid, hederagenin and gypsogenin aglycones, and some C-28 ester derivatives. ChemistryOpen, 4(6), 740-755. doi: 10.1002/open.201500149

Kojarunchitt, T., Baldursdottir, S., Dong, Y.-D., Boyd, B. J., Rades, T., & Hook, S. (2015). Modified thermoresponsive Poloxamer 407 and chitosan sol-gels as potential sustained-release vaccine delivery systems. European Journal of Pharmaceutics & Biopharmaceutics, 89, 74-81. doi: 10.1016/j.ejpb.2014.11.026

Engelke, L., Winter, G., Hook, S., & Engert, J. (2015). Recent insights into cutaneous immunization: How to vaccinate via the skin. Vaccine, 33, 4663-4674. doi: 10.1016/j.vaccine.2015.05.012

Even, M.-P., Bobbala, S., Kok, L. K., Hook, S., Winter, G., & Engert, J. (2015). Impact of implant composition of twin-screw extruded lipid implants on the release behavior. International Journal of Pharmaceutics, 493, 102-110. doi: 10.1016/j.ijpharm.2015.06.052

Scherließ, R., Mönckedieck, M., Young, K., Trows, S., Buske, S., & Hook, S. (2015). First in vivo evaluation of particulate nasal dry powder vaccine formulations containing ovalbumin in mice. International Journal of Pharmaceutics, 479(2), 408-415. doi: 10.1016/j.ijpharm.2015.01.015

Bobbala, S., McDowell, A., & Hook, S. (2015). Quantitation of the immunological adjuvants, monophosphoryl lipid A and Quil A in poly (lactic-co-glycolic acid) nanoparticles using high performance liquid chromatography with evaporative light scattering detection. Journal of Chromatography B, 975, 45-51. doi: 10.1016/j.jchromb.2014.11.006

Highton, A. J., Kojarunchitt, T., Girardin, A., Hook, S., & Kemp, R. A. (2015). Chitosan hydrogel vaccine generates protective CD8 T cell memory against mouse melanoma. Immunology & Cell Biology, 93, 634-640. doi: 10.1038/icb.2015.14

Kaneko, K., McDowell, A., Ishii, Y., & Hook, S. (2015). Selective quantitation of the incorporation of the immunomodulator α-galactosylceramide in liposomes using LC-MS/MS. International Journal of Mass Spectrometry, 392, 96-101. doi: 10.1016/j.ijms.2015.09.016

Liau, J. J., Hook, S., Prestidge, C. A., & Barnes, T. J. (2015). A lipid based multi-compartmental system: Liposomes-in-double emulsion for oral vaccine delivery. European Journal of Pharmaceutics & Biopharmaceutics, 97, 15-21. doi: 10.1016/j.ejpb.2015.09.018

Hubert, M., Larsen, D. S., Hayman, C. M., Rades, T., & Hook, S. (2014). Physical characterization of synthetic phosphatidylinositol dimannosides and analogues in binary systems with phosphatidylcholine. Molecular Pharmaceutics, 11(3), 913-921. doi: 10.1021/mp400588y

Even, M.-P., Young, K., Winter, G., Hook, S., & Engert, J. (2014). In vivo investigation of twin-screw extruded lipid implants for vaccine delivery. European Journal of Pharmaceutics & Biopharmaceutics, 87(2), 338-346. doi: 10.1016/j.ejpb.2014.02.014

Rattanapak, T., Birchall, J. C., Young, K., Kubo, A., Fujimori, S., Ishii, M., & Hook, S. (2014). Dynamic visualization of dendritic cell-antigen interactions in the skin following transcutaneous immunization. PLoS ONE, 9(2), e89503. doi: 10.1371/journal.pone.0089503

Neumann, S., Burkert, K., Kemp, R., Rades, T., Dunbar, P. R., & Hook, S. (2014). Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants. Immunology & Cell Biology, 92, 535-542. doi: 10.1038/icb.2014.21

Hubert, M., Compton, B. J., Hayman, C. M., Larsen, D. S., Painter, G. F., Rades, T., & Hook, S. (2013). Physicochemical and biological characterization of synthetic phosphatidylinositol dimannosides and analogues. Molecular Pharmaceutics, 10(5), 1928-1939. doi: 10.1021/mp300707a

Scherließ, R., Buske, S., Young, K., Weber, B., Rades, T., & Hook, S. (2013). In vivo evaluation of chitosan as an adjuvant in subcutaneous vaccine formulations. Vaccine, 31(42), 4812-4819. doi: 10.1016/j.vaccine.2013.07.081

Rizwan, S. B., McBurney, W. T., Young, K., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2013). Cubosomes containing the adjuvants imiquimod and monophosphoryl lipid A stimulate robust cellular and humoral immune responses. Journal of Controlled Release, 165(1), 16-21. doi: 10.1016/j.jconrel.2012.10.020

Rattanapak, T., Birchall, J., Young, K., Ishii, M., Meglinski, I., Rades, T., & Hook, S. (2013). Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and two-photon microscopy. Journal of Controlled Release, 172(3), 894-903. doi: 10.1016/j.jconrel.2013.08.018

Gordon, S., Young, K., Wilson, R., Rizwan, S., Kemp, R., Rades, T., & Hook, S. (2012). Chitosan hydrogels containing liposomes and cubosomes as particulate sustained release vaccine delivery systems. Journal of Liposome Research, 22(3), 193-204. doi: 10.3109/08982104.2011.637502

Kamali, T., Doronin, A., Rattanapak, T., Hook, S., & Meglinski, I. (2012). Assessment of transcutaneous vaccine delivery by optical coherence tomography. Laser Physics Letters, 9(8), 607-610. doi: 10.7452/lapl.201210046

Rattanapak, T., Young, K., Rades, T., & Hook, S. (2012). Comparative study of liposomes, transfersomes, ethosomes and cubosomes for transcutaneous immunisation: Characterisation and in vitro skin penetration. Journal of Pharmacy & Pharmacology, 64(11), 1560-1569. doi: 10.1111/j.2042-7158.2012.01535.x

Rizwan, S. B., Assmus, D., Boehnke, A., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2011). Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines. European Journal of Pharmaceutics & Biopharmaceutics, 79(1), 15-22. doi: 10.1016/j.ejpb.2010.12.034

Kojarunchitt, T., Hook, S., Rizwan, S., Rades, T., & Baldursdottir, S. (2011). Development and characterisation of modified poloxamer 407 thermoresponsive depot systems containing cubosomes. International Journal of Pharmaceutics, 408(1-2), 20-26. doi: 10.1016/j.ijpharm.2011.01.037

Hook, S. M., Phipps-Green, A. J., Faiz, F., McNoe, L., McKinney, C., Hollis-Moffatt, J. E., & Merriman, T. R. (2011). Smad2: A candidate gene for the murine autoimmune diabetes locus Idd21.1. Journal of Clinical Endocrinology & Metabolism, 96(12), E2072-E2077. doi: 10.1210/jc.2011-0463

Gordon, S., Teichmann, E., Young, K., Finnie, K., Rades, T., & Hook, S. (2010). In vitro and in vivo investigation of thermosensitive chitosan hydrogels containing silica nanoparticles for vaccine delivery. European Journal of Pharmaceutical Sciences, 41(2), 360-368. doi: 10.1016/j.ejps.2010.07.004

Rizwan, S. B., Boyd, B. J., Rades, T., & Hook, S. (2010). Bicontinuous cubic liquid crystals as sustained delivery systems for peptides and proteins. Expert Opinion on Drug Delivery, 7(10), 1133-1144. doi: 10.1517/17425247.2010.515584

Braund, R., Hook, S. M., Greenhill, N., & Medlicott, N. J. (2009). Distribution of fibroblast growth factor-2 (FGF-2) within model excisional wounds following topical application. Journal of Pharmacy & Pharmacology, 61(2), 193-200. doi: 10.1211/jpp/61.02.0008

Greatrex, B. W., Brodie, S. J., Furneaux, R. H., Hook, S. M., McBurney, W. T., Painter, G. F., Rades, T., & Rendle, P. M. (2009). The synthesis and immune stimulating action of mannose-capped lysine-based dendrimers. Tetrahedron, 65(15), 2939-2950. doi: 10.1016/j.tet.2009.02.018

Daines, A. M., Greatrex, B. W., Hayman, C. M., Hook, S. M., McBurney, W. T., Rades, T., … Sims, I. M. (2009). Mannosylated saponins based on oleanolic and glycyrrhizic acids. Towards synthetic colloidal antigen delivery systems. Bioorganic & Medicinal Chemistry, 17(14), 5207-5218. doi: 10.1016/j.bmc.2009.05.043

Graf, A., Rades, T., & Hook, S. M. (2009). Oral insulin delivery using nanoparticles based on microemulsions with different structure-types: Optimisation and in vivo evaluation. European Journal of Pharmaceutical Sciences, 37(1), 53-61. doi: 10.1016/j.ejps.2008.12.017

Myschik, J., Rades, T., & Hook, S. (2009). Advances in lipid-based subunit vaccine formulations. Current Immunology Reviews, 5(1), 42-48.

Ferderber, K., Hook, S., & Rades, T. (2009). Phosphatidyl choline-based colloidal systems for dermal and transdermal drug delivery. Journal of Liposome Research, 19(4), 267-277. doi: 10.3109/08982100902814006

Rizwan, S. B., Hanley, T., Boyd, B. J., Rades, T., & Hook, S. (2009). Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: Characterisation, swelling and release kinetics. Journal of Pharmaceutical Sciences, 98(11), 4191-4204. doi: 10.1002/jps.21724

Graf, A., Jack, K. S., Whittaker, A. K., Hook, S. M., & Rades, T. (2008). Protein delivery using nanoparticles based on microemulsions with different structure-types. European Journal of Pharmaceutical Sciences, 33, 434-444.

Graf, A., Ablinger, E., Peters, S., Zimmer, A., Hook, S., & Rades, T. (2008). Microemulsions containing lecithin and sugar-based surfactants: Nanoparticle templates for delivery of proteins and peptides. International Journal of Pharmaceutics, 350, 351-360. doi: 10.1016/j.ijpharm.2007.08.053

Myschik, J., McBurney, W. T., Hennessy, T., Phipps-Green, A., Rades, T., & Hook, S. (2008). Immunostimulatory biodegradable implants containing the adjuvant Quil-A - Part II: In vivo evaluation. Journal of Drug Targeting, 16(3), 224-232. doi: 10.1080/10611860701848886

Myschik, J., Eberhardt, F., Rades, T., & Hook, S. (2008). Immunostimulatory biodegradable implants containing the adjuvant Quil-A - Part I: Physicochemical characterisation. Journal of Drug Targeting, 16(3), 213-223. doi: 10.1080/10611860701848860

Myschik, J., McBurney, W. T., Rades, T., & Hook, S. (2008). Immunostimulatory lipid implants containing Quil-A and DC-cholesterol. International Journal of Pharmaceutics, 363, 91-98. doi: 10.1016/j.ijpharm.2008.07.014

McBurney, W. T., Lendemans, D. G., Myschik, J., Hennessy, T., Rades, T., & Hook, S. (2008). In vivo activity of cationic immune stimulating complexes (PLUSCOMs). Vaccine, 26, 4549-4556. doi: 10.1016/j.vaccine.2008.06.024

Myschik, J., McBurney, W. T., Hennessy, T., Rades, T., & Hook, S. (2008). Immunogenicity of lipid sustained release implants containing imiquimod, α-galactosylceramide, or Quil-A. Pharmazie, 63(9), 686-692. doi: 10.1691/ph.2008.8072

Gordon, S., Saupe, A., McBurney, W., Rades, T., & Hook, S. (2008). Comparison of chitosan nanoparticles and chitosan hydrogels for vaccine delivery. Journal of Pharmacy & Pharmacology, 60, 1591-1600. doi: 10.1211/jpp/60.12.0004

Demana, P. H., Davies, N. M., Hook, S., & Rades, T. (2007). Analysis of Quil A-phospholipid mixtures using drift spectroscopy. International Journal of Pharmaceutics, 342, 49-61.

Lendemans, D. G., Egert, A. M., Hook, S., & Rades, T. (2007). Cage-like complexes formed by DOTAP, Quil-A and cholesterol. International Journal of Pharmaceutics, 332, 192-195.

Krauel, K., Girvan, L., Hook, S., & Rades, T. (2007). Characterisation of colloidal drug delivery systems from the naked eye to Cryo-FESEM. Micron, 38, 796-803.

Boyd, B. J., Rizwan, S. B., Dong, Y.-D., Hook, S., & Rades, T. (2007). Self-assembled geometric liquid-crystalline nanoparticles imaged in three dimensions: Hexosomes are not necessarily flat hexagonal prisms. Langmuir, 23(25), 12461-12464. doi: 10.1021/la7029714

Rizwan, S. B., Dong, Y.-D., Boyd, B. J., Rades, T., & Hook, S. (2007). Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM). Micron, 38, 478-485. doi: 10.1016/j.micron.2006.08.003

Weir, C., McNeill, A., Hook, S., Harvie, M., La Flamme, A. C., Le Gros, G., & Bäckström, B. T. (2006). Critical role of preproenkephalin in experimental autoimmune encephalomyelitis. Journal of Neuroimmunology, 179, 18-25.

White, K., Rades, T., Kearns, P., Toth, I., & Hook, S. (2006). Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A. Pharmaceutical Research, 23(7), 1473-1481.

Saupe, A., McBurney, W., Rades, T., & Hook, S. (2006). Immunostimulatory colloidal delivery systems for cancer vaccines. Expert Opinion on Drug Delivery, 3(3), 345-354.

White, K. L., Rades, T., Furneaux, R. H., Tyler, P. C., & Hook, S. (2006). Mannosylated liposomes as antigen delivery vehicles for targeting to dendritic cells. Journal of Pharmacy & Pharmacology, 58, 729-737.

Myschik, J., Lendemans, D. G., McBurney, W. T., Demana, P. H., Hook, S., & Rades, T. (2006). On the preparation, microscopic investigation and application of ISCOMs. Micron, 37, 724-734.

Lendemans, D. G., Egert, A. M., Myschik, J., Hook, S., & Rades, T. (2006). On the dilution behaviour of immuno-stimulating complexes (ISCOMs). Pharmazie, 61(8), 689-695.

Krauel, K., Graf, A., Hook, S. M., Davies, N. M., & Rades, T. (2006). Preparation of poly (alkylcyanoacrylate) nanoparticles by polymerization of water-free microemulsions. Journal of Microencapsulation, 23(5), 499-512.

Grimwood, K., Huang, Q. S., Cohet, C., Gosling, I. A., Hook, S. M., Teele, D. W., … Leadbitter, P., & Lennon, D. R. (2006). Rotavirus hospitalisation in New Zealand children under 3 years of age. Journal of Paediatrics & Child Health, 42(4), 196-203. doi: 10.1111/j.1440-1754.2006.00829.x

Lendemans, D. G., Myschik, J., Hook, S., & Rades, T. (2005). Cationic cage-like complexes formed by DC-cholestrol, Quil-A, and phospholipid. Journal of Pharmaceutical Sciences, 94(8), 1794-1807.

Hook, S., Chan, L., Cutfield, H., Dean, R., Keir, A., Gordon, G., & Norris, P. (2005). Immunisation knowledge and beliefs of health science and non-health science students at the University of Otago. New Zealand Family Physician, 32(6), 394-398.

Demana, P. H., Davies, N. M., Hook, S., & Rades, T. (2005). Quil A-lipid powder formulations releasing ISCOMs and related colloidal stuctures upon hydration. Journal of Controlled Release, 103, 45-59.

Chen, Y. E., Beasley, S., Grimwood, K., and the New Zealand Rotavirus Study Group, including Hook, S. (2005). Intussusception and rotavirus associated hospitalisation in New Zealand. Archives of Disease in Childhood, 90, 1077-1081. doi: 10.1136/adc.2005.074104

Hollis-Moffatt, J. E., Hook, S. M., & Merriman, T. R. (2005). Colocalization of mouse autoimmune diabetes loci Idd21.1 and Idd21.2 with IddM6 (Human) and Iddm3 (Rat) [Brief Genetics Report]. Diabetes, 54, 2820-2825.

Krauel, K., Davies, N. M., Hook, S., & Rades, T. (2005). Using different structure types of microemulsions for the preparation of poly(alkylcyanoacrylate) nanoparticles by interfacial polymerization. Journal of Controlled Release, 106(1-2), 76-87. doi: 10.1016/j.jconrel.2005.04.013

Armstrong, D. S., Hook, S. M., Jamsen, K. M., Nixon, G. M., Carzino, R., Carlin, J. B., … Grimwood, K. (2005). Lower airway inflammation in infants with cystic fibrosis detected by newborn screening. Pediatric Pulmonology, 40, 500-510.

Lendemans, D. G., Myschik, J., Hook, S., & Rades, T. (2005). Immuno-stimulating complexes prepared by ethanol injection. Journal of Pharmacy & Pharmacology, 57, 729-733.

Demana, P. H., Fehske, C., White, K., Rades, T., & Hook, S. (2004). Effect of incorporation of the adjuvant Quil A on structure and immune stimulatory capacity of liposomes. Immunology & Cell Biology, 82, 547-554.

Marsland, B. J., Harris, N. L., Camberis, M., Kopf, M., Hook, S. M., & Le Gros, G. (2004). Bystander suppression of allergic airway inflammation by lung resident memory CD8+ T cells. PNAS, 101(16), 6116-6121.

White, K., Kearns, P., Toth, I., & Hook, S. (2004). Increased adjuvant activity of minimal CD8 T cell peptides incorporated into lipid-core-peptides. Immunology & Cell Biology, 82, 517-522. doi: 10.1111/j.0818-9641.2004.01269.x

Hook, S. M., Camberis, M., Prout, M., & Le Gros, G. (2003). Absence of preproenkephalin increases the threshold for T cell activation. Journal of Neuroimmunology, 140, 61-68.

Hook, S. M., & Le Gros, G. (2002). Immunomodulatory effects of preproenkephalin. Current Opinions in European Medicine, 3, 68-80.

Hook, S. M., Prout, M., Camberis, M., Konig, M., Zimmer, A., & Le Gros, G. (2000). Th2 dependent airway eosinophilia is regulated by preproenkephalin. Journal of Neuroimmunology, 107, 59-65.

Hook, S., Cheng, P., Holloway, J. W., Riley, G., Sawyer, G., Le Gros, G., & Beasley, R. (1999). Analysis of two IL-4 promoter polymorphisms in a cohort of atopic and asthmatic subjects. Experimental & Clinical Immunogenetics, 16(1), 33-35. doi: 10.1159/000019094

Hook, S., Camberis, M., Prout, M., Konig, M., Zimmer, A., van Heeke, G., & Le Gros, G. (1999). Preproenkephalin is a Th2 cytokine but is not required for Th2 differentiation in vitro. Immunology & Cell Biology, 77, 385-390. doi: 10.1046/j.1440-1711.1999.00842.x

Kirman, J., McCoy, K. D., Hook, S., Prout, M., Delahunt, B., Orme, I., … Le Gros, G. (1999). CTLA-4 blockade enhances the immune response induced by mycobacterial infection but does not lead to increased protection. Infection & Immunity, 67(8), 3786-3792.

Hook, S., Griffin, F., Mackintosh, C., & Buchan, G. (1996). Activation of an interleukin-4 mRNA-producing population of peripheral blood mononuclear cells after infection with Mycobacterium bovis or vaccination with killed, but not live, BCG. Immunology, 88, 269-274.

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Journal - Research Other

Hook, S., & Windle, J. (2013). Community pharmacy influenza immunisation increases vaccine uptake and gains public approval. Australian & New Zealand Journal of Public Health, 37(5), 489-490. doi: 10.1111/1753-6405.12109

Braund, R., Hook, S., & Medlicott, N. J. (2007). The role of topical growth factors in chronic wounds. Current Drug Delivery, 4, 195-204.

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