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Professor Neil McNaughton

Neil McNaughton

Email nmcn@psy.otago.ac.nz
Tel 64 3 479 7634

Professor Neil McNaughton has been extensively involved in the development of Neuroscience at Otago. He was involved in the setting up of the undergraduate Neuroscience programme (the only one of its kind in New Zealand) and was director of the programme from 1991–2008. He was director of the Neuroscience Research Centre from 1991–1997 and the Neural Systems Structure and Function Research Theme from 1997–2005. He was one of the founders of the Australasian Winter Conference on Brain research and the Treasurer from 1983–1997 and a committee member until 2009.

He has acted as an External Assessor for Personal Chairs, Awards and Promotions for the Institute of Psychiatry, London; University of Hong Kong; University of Hawaii; NHMRC Australia Fellowship; Australian National University; and National University of Singapore. He has refereed grants for 15 grant awarding bodies and papers for 48 journals.

Neil joined the Department in 1982. He has over 30 years of university teaching experience, teaching at both graduate and undergraduate levels. He has over 40 years work experience as a Neuroscience researcher in the UK, Canada and New Zealand. His research interests are multidisciplinary. He has authored 111 papers, 5 major reviews, 2 books, and 30 book chapters; and edited 4 book-length works.

Research Interests

  • Neurobiology of State and Trait Anxiety and Temporal-Frontal Lobe Interactions

Find out more about Professor McNaughton's research interests

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Publications

Glue, P., Medlicott, N. J., Harland, S., Neehoff, S., Anderson-Fahey, B., Le Nedelec, M., Gray, A., & McNaughton, N. (2017). Ketamine's dose-related effects on anxiety symptoms in patients with treatment refractory anxiety disorders. Journal of Psychopharmacology, 31(10), 1302-1305. doi: 10.1177/0269881117705089

Young, C. K., Ruan, M., & McNaughton, N. (2017). A critical assessment of directed connectivity estimates with artificially imposed causality in the supramammillary-septo-hippocampal circuit. Frontiers in Systems Neuroscience, 11, 72. doi: 10.3389/fnsys.2017.00072

Frost, R., & McNaughton, N. (2017). The neural basis of delay discounting: A review and preliminary model. Neuroscience & Biobehavioral Reviews. Advance online publication. doi: 10.1016/j.neubiorev.2017.04.022

Ruan, M., Young, C. K., & McNaughton, N. (2017). Bi-directional theta modulation between the septo-hippocampal system and the mammillary area in free-moving rats. Frontiers in Neural Circuits, 11, 62. doi: 10.3389/fncir.2017.00062

Zhang, S., McIntosh, J., Shadli, S. M., Neo, P. S.-H., Huang, Z., & McNaughton, N. (2017). Removing eye blink artefacts from EEG: A single-channel physiology-based method. Journal of Neuroscience Methods, 291, 213-220. doi: 10.1016/j.jneumeth.2017.08.031

Authored Book - Research

Gray, J. A., & McNaughton, N. (2000). The Neuropsychology of Anxiety: An Enquiry into the Functions of the Septo-Hippocampal System (Second Edition). Oxford, UK: Oxford University Press, 424p.

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Chapter in Book - Research

McNaughton, N., DeYoung, C. G., & Corr, P. J. (2016). Approach/Avoidance. In J. R. Absher & J. Cloutier (Eds.), Neuroimaging personality, social cognition, and character. (pp. 25-49). London, UK: Academic Press. doi: 10.1016/B978-0-12-800935-2.00002-6

Corr, P. J., & McNaughton, N. (2015). Neural mechanisms of low trait anxiety and risk for externalizing behavior. In T. P. Beauchaine & S. P. Hinshaw (Eds.), The Oxford handbook of externalizing spectrum disorders. Oxford University Press. doi: 10.1093/oxfordhb/9780199324675.013.1

McNaughton, N. (2010). Approach-avoidance conflict. In I. B. Weiner & W. E. Craighead (Eds.), The Corsini encyclopedia of psychology (Vol. 1). (4th ed.) (pp. 138-139). Hoboken, NJ: John Wiley & Sons.

McNaughton, N., & Corr, P. J. (2009). Central theories of motivation and emotion. In G. G. Berntson & J. T. Cacioppo (Eds.), Handbook of neuroscience for the behavioral sciences. (pp. 710-730). Hoboken, NJ: John Wiley & Sons.

McNaughton, N. (2008). The neurobiology of anxiety: Potential for co-morbidity of anxiety and substance use disorders. In S. H. Stewart & P. J. Conrod (Eds.), Anxiety and substance use disorders: The vicious cycle of comorbidity. (pp. 19-33). NY: Springer. doi: 10.1007/978-0-387-74290-8_2

McNaughton, N., & Corr, P. J. (2008). Animal cognition and human personality. In P. J. Corr (Ed.), The reinforcement sensitivity theory of personality. (pp. 95-119). Cambridge University Press.

Corr, P. J., & McNaughton, N. (2008). Reinforcement sensitivity theory and personality. In P. J. Corr (Ed.), The reinforcement sensitivity theory of personality. (pp. 155-187). Cambridge University Press.

McNaughton, N., & Corr, P. J. (2008). The neuropsychology of fear and anxiety: A foundation for reinforcement sensitivity theory. In P. J. Corr (Ed.), The reinforcement sensitivity theory of personality. (pp. 44-94). Cambridge University Press.

McNaughton, N., & Zangrossi, Jr, H. (2008). Theoretical approaches to the modeling of anxiety in animals. In R. J. Blanchard, D. C. Blanchard, G. Griebel & D. J. Nutt (Eds.), Handbook of anxiety and fear (Vol. 17). (pp. 11-27). Amsterdam: Academic Press. doi: 10.1016/S1569-7339(07)00002-1

McNaughton, N. (2002). Aminergic transmitter systems. In H. D'haenen, J. A. den Boer & P. Willner (Eds.), Biological Psychiatry, Volume 1. (Volume ed.) (pp. 895-913). Chichester: John Wiley & Sons, Ltd.

McNaughton, N. (2001). Approach-avoidance conflict. In W. E. Craighead & C. B. Nemeroff (Eds.), The Corsini Encyclopedia of Psychology and Behavioral Science. (3rd Edition, Volume 1). (pp. 126-127). NY: John Wiley & Sons.

McNaughton, N. (2000). Implications of the neuropsychology of anxiety for the functional role of LTP in the hippocampus. In C. Hölscher (Ed.), Neuronal Mechanisms of Memory Formation: Concepts of Long-Term Potentiation and Beyond. (pp. 362-378). Cambridge, UK: Cambridge University Press.

Gray, J. A., & McNaughton, N. (1996). The neuropsychology of anxiety: reprise. In D. A. Hope (Ed.), Perspectives on Anxiety, Panic and Fear. (pp. 61-134). Lincoln, Nebraska: University of Nebraska Press.

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Chapter in Book - Other

McNaughton, N. (2004). The neuropsychology of defence: Implications for syndromes and pharmacotherapy. In M. Maj, H. S. Akiskal, J. J. López-Ibor & A. Okasha (Eds.), Phobias. (pp. 148-152). John Wiley & Sons.

Gray, J., & McNaughton, N. (2004). Ansiedad: La conexión hipocámpica. In J. Vallejo, L. Sánchez Planell, C. Diez-Quevedo & J. M. Menchón (Eds.), La neurosis de angustia en el siglo XXI. (pp. 61-84). Barcelona: Ars Medica.

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Journal - Research Article

Glue, P., Medlicott, N. J., Harland, S., Neehoff, S., Anderson-Fahey, B., Le Nedelec, M., Gray, A., & McNaughton, N. (2017). Ketamine's dose-related effects on anxiety symptoms in patients with treatment refractory anxiety disorders. Journal of Psychopharmacology, 31(10), 1302-1305. doi: 10.1177/0269881117705089

Zhang, S., McIntosh, J., Shadli, S. M., Neo, P. S.-H., Huang, Z., & McNaughton, N. (2017). Removing eye blink artefacts from EEG: A single-channel physiology-based method. Journal of Neuroscience Methods, 291, 213-220. doi: 10.1016/j.jneumeth.2017.08.031

Ruan, M., Young, C. K., & McNaughton, N. (2017). Bi-directional theta modulation between the septo-hippocampal system and the mammillary area in free-moving rats. Frontiers in Neural Circuits, 11, 62. doi: 10.3389/fncir.2017.00062

Frost, R., & McNaughton, N. (2017). The neural basis of delay discounting: A review and preliminary model. Neuroscience & Biobehavioral Reviews. Advance online publication. doi: 10.1016/j.neubiorev.2017.04.022

Young, C. K., Ruan, M., & McNaughton, N. (2017). A critical assessment of directed connectivity estimates with artificially imposed causality in the supramammillary-septo-hippocampal circuit. Frontiers in Systems Neuroscience, 11, 72. doi: 10.3389/fnsys.2017.00072

McNaughton, N., & Corr, P. J. (2016). Mechanisms of comorbidity, continuity, and discontinuity in anxiety-related disorders. Development & Psychopathology, 28(4, Pt. 1), 1053-1069. doi: 10.1017/s0954579416000699

Shadli, S. M., Smith, M. J., Glue, P., & McNaughton, N. (2016). Testing an anxiety process biomarker: Generalisation from an auditory to a visual stimulus. Biological Psychology, 117, 50-55. doi: 10.1016/j.biopsycho.2016.02.011

Tyree, S. M., Munn, R. G. K., & McNaughton, N. (2016). Anxiolytic-like effects of leptin on fixed interval responding. Pharmacology Biochemistry & Behavior, 148, 15-20. doi: 10.1016/j.pbb.2016.05.005

Munn, R. G. K., Tyree, S. M., McNaughton, N., & Bilkey, D. K. (2015). The frequency of hippocampal theta rhythm is modulated on a circadian period and is entrained by food availability. Frontiers in Behavioral Neuroscience, 9, 61. doi: 10.3389/fnbeh.2015.00061

Shadli, S. M., Glue, P., McIntosh, J., & McNaughton, N. (2015). An improved human anxiety process biomarker: Characterization of frequency band, personality and pharmacology. Translational Psychiatry, 5, e699. doi: 10.1038/tp.2015.188

Dalrymple-Alford, J. C., Harland, B., Loukavenko, E. A., Perry, B., Mercer, S., Collings, D. A., Ulrich, K., Abraham, W. C., McNaughton, N., & Wolff, M. (2015). Anterior thalamic nuclei lesions and recovery of function: Relevance to cognitive thalamus. Neuroscience & Biobehavioral Reviews, 54, 145-160. doi: 10.1016/j.neubiorev.2014.12.007

McNaughton, N. (2014). Development of a theoretically-derived human anxiety syndrome biomarker. Translational Neuroscience, 5(2), 137-146. doi: 10.2478/s13380-014-0220-z

Harland, B. C., Collings, D. A., McNaughton, N., Abraham, W. C., & Dalrymple-Alford, J. C. (2014). Anterior thalamic lesions reduce spine density in both hippocampal CA1 and retrosplenial cortex, but enrichment rescues CA1 spines only. Hippocampus, 24, 1232-1247. doi: 10.1002/hipo.22309

Ulrich, K., Aitken, P. N., Abraham, W. C., Dalrymple-Alford, J. C., & McNaughton, N. (2014). Effects of thalamic lesions on repeated re-learning of a spatial working memory task. Behavioural Brain Research, 261, 56-59. doi: 10.1016/j.bbr.2013.12.002

Corr, P. J., DeYoung, C. G., & McNaughton, N. (2013). Motivation and personality: A neuropsychological perspective. Social & Personality Psychology Compass, 7(3), 158-175. doi: 10.1111/spc3.12016

McNaughton, N., Swart, C., Neo, P., Bates, V., & Glue, P. (2013). Anti-anxiety drugs reduce conflict-specific “theta”: A possible human anxiety-specific biomarker. Journal of Affective Disorders, 148(1), 104-111. doi: 10.1016/j.jad.2012.11.057

Stevenson, M., & McNaughton, N. (2013). A comparison of phenylketonuria with attention deficit hyperactivity disorder: Do markedly different aetiologies deliver common phenotypes? Brain Research Bulletin, 99, 63-83. doi: 10.1016/j.brainresbull.2013.10.003

Neo, P., Carter, D., Zheng, Y., Smith, P., Darlington, C., & McNaughton, N. (2012). Septal elicitation of hippocampal theta rhythm did not repair cognitive and emotional deficits resulting from vestibular lesions. Hippocampus, 22(5), 1176-1187. doi: 10.1002/hipo.20963

Corr, P. J., & McNaughton, N. (2012). Neuroscience and approach/avoidance personality traits: A two stage (valuation–motivation) approach. Neuroscience & Biobehavioral Reviews, 36, 2339-2354. doi: 10.1016/j.neubiorev.2012.09.013

McNaughton, N. (2011). Trait anxiety, trait fear and emotionality: The perspective from non-human studies. Personality & Individual Differences, 50(7), 898-906. doi: 10.1016/j.paid.2010.07.011

Hall, P. J., Chong, C. W., McNaughton, N., & Corr, P. J. (2011). An economic perspective on the Reinforcement Sensitivity Theory of personality. Personality & Individual Differences, 51(3), 242-247. doi: 10.1016/j.paid.2010.06.023

McNaughton, N. (2011). Fear, anxiety and their disorders: Past, present and future neural theories. Psychology & Neuroscience, 4(2), 173-181. doi: 10.3922/j.psns.2011.2.002

Neo, P. S.-H., Thurlow, J. K., & McNaughton, N. (2011). Stopping, goal-conflict, trait anxiety and frontal rhythmic power in the stop-signal task. Cognitive, Affective, & Behavioral Neuroscience, 11(4), 485-493. doi: 10.3758/s13415-011-0046-x

Neo, P. S.-H., & McNaughton, N. (2011). Frontal theta power linked to neuroticism and avoidance. Cognitive, Affective, & Behavioral Neuroscience, 11(3), 396-403. doi: 10.3758/s13415-011-0038-x

Ruan, M., Young, C. K., & McNaughton, N. (2010). Minimal driving of hippocampal theta by the supramammillary nucleus during water maze learning. Hippocampus, 21(10), 1074-1081. doi: 10.1002/hipo.20821

Young, C., & McNaughton, N. (2009). Coupling of theta oscillations between anterior and posterior midline cortex and with the hippocampus in freely behaving rats. Cerebral Cortex, 19(1), 24-40. doi: 10.1093/cercor/bhn055

Sutherland, K. R., Alsop, B., McNaughton, N., Hyland, B. I., Tripp, G., & Wickens, J. R. (2009). Sensitivity to delay of reinforcement in two animal models of attention deficit hyperactivity disorder (ADHD). Behavioural Brain Research, 205(2), 372-376. doi: 10.1016/j.bbr.2009.07.011

Munn, R. G. K., & McNaughton, N. (2008). Effects of fluoxetine on hippocampal rhythmic slow activity and behavioural inhibition. Behavioural Pharmacology, 19, 257-264. doi: 10.1097/FBP.0b013e3282ff1300

Mitchell, D. J., McNaughton, N., Flanagan, D., & Kirk, I. J. (2008). Frontal-midline theta from the perspective of hippocampal ″theta″. Progress in Neurobiology, 86(3), 156-185. doi: 10.1016/j.pneurobio.2008.09.005

McNaughton, N., Kocsis, B., & Hajós, M. (2007). Elicited hippocampal theta rhythm: A screen for anxiolytic and procognitive drugs through changes in hippocampal function? Behavioural Pharmacology, 18(5 & 6), 329-346.

McNaughton, N. (2006). The role of the subiculum within the behavioural inhibition system. Behavioural Brain Research, 174, 232-250.

McNaughton, N., Ruan, M., & Woodnorth, M.-A. (2006). Restoring theta-like rhythmicity in rats restores initial learning in the Morris water maze. Hippocampus, 16, 1102-1110.

Nerad, L., & McNaughton, N. (2006). The septal EEG suggests a distributed organization of the pacemaker of hippocampal theta in the rat. European Journal of Neuroscience, 24, 155-166.

Woodnorth, M.-A., & McNaughton, N. (2005). Different systems in the posterior hypothalamic nucleus of rats control theta frequency and trigger movement. Behavioural Brain Research, 163, 107-114.

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