Contact Details
- Phone
- 64 3 479 7126
- lara.friedlander@otago.ac.nz
University Links
- Position
- Associate Professor and Discipline Head - Endodontics
- Department
- Department of Oral Rehabilitation
- Qualifications
- BDS MDS PhD(Otago) FRACDS FICD
- Research summary
- Endodontics, practice-based research, dental education, immunopathology
- Teaching
- Chair, Final Year Dentistry
- Course Co-ordinator Clinical Practice for General Dentistry
- Clinical Co-ordinator of Clinical Doctorate in Endodontics
- Clinical
- Specialist endodontics with particular interest in immature permanent teeth, vital pulp therapy and regeneration.
Research
Associate Professor Lara Friedlander is a Specialist Endodontist with research in the areas of pulp development and disease, practice-based research, dental education and immunopathology. She is deputy director of the Immunopathology Research Group of the Sir John Walsh Research Institute.
Associate Professor Friedlander has developed research themes in pulpal biology, regeneration and angiogenesis; and separate from this is also active in research related to Endodontic curriculum development and teaching.
Results of her PhD research around pulp biology and angiogenesis associated with immature permanent teeth have been presented at international conferences and published in internationally peer-reviewed journals. This work has influenced clinical practice by providing further knowledge about pulp cell behaviour and healing following dental trauma.
As main author she has published on Endodontic teaching and this work is on-going and now looking at 5 year outcomes. Dr Friedlander was invited to Switzerland to speak on endodontic curriculum development at the University Forum of 160 international universities and has been an invited international judge on a research panel.
Lara is a co-supervisor of Clinical Doctorate students and has PhD student supervision. She has had substantial competitive grant applications associated with these. Lara assists in advising on projects and funding applications including PhD pulp research which has evolved from her own research theme.
Associate Professor Friedlander enjoys engaging with general dentists in practice-based research and is a member of the New Zealand Dental Research Foundation Board.
Additional details
Senior Examiner for Final examination for Fellowship with the Royal Australasian College of Dental SurgeonsPublications
Lundy, F. T., Friedlander, L. T., & Cooper, P. R. (2024). Biological basis for vital pulp treatment. In H. F. Duncan & I. A. El-Karim (Eds.), Vital pulp treatment. (pp. 20-46). Hoboken, NJ: John Wiley & Sons. doi: 10.1002/9781119930419.ch2
Dohan, Z., Friedlander, L. T., Cooper, P. R., Li, K.-C., Ratnayake, J. T., & Mei, M. L. (2023). In vitro models used in the formation of root caries lesions: A review of the literature. Dentistry Journal, 11, 269. doi: 10.3390/dj11120269
Friedlander, L. T., Wallace, W. D. A., Broadbent, J. M., Hanlin, S. M., Lyons, K. M., Cannon, R. D., & Cooper, P. R. (2023). Preparedness and competency of New Zealand graduates for general dental practice: Perceptions from the workforce. Australian Dental Journal. Advance online publication. doi: 10.1111/adj.12981
Alsamahi, S., Milne, T. J., Hussaini, H. M., Rich, A. M., Cooper, P. R., & Friedlander, L. T. (2023). Effects of glycation end-products on the dental pulp in patients with type 2 diabetes. International Endodontic Journal, 56, 1373-1384. doi: 10.1111/iej.13966
Friedlander, L., Hunt, G., Chandler, N., & Daniel, B. (2023). Students' experience and perceptions of undergraduate endodontic education in New Zealand. Australian Endodontic Journal. Advance online publication. doi: 10.1111/aej.12770
Lundy, F. T., Friedlander, L. T., & Cooper, P. R. (2024). Biological basis for vital pulp treatment. In H. F. Duncan & I. A. El-Karim (Eds.), Vital pulp treatment. (pp. 20-46). Hoboken, NJ: John Wiley & Sons. doi: 10.1002/9781119930419.ch2
Chapter in Book - Research
Arora, S., Seo, B., Friedlander, L., & Hussaini, H. M. (2023). A cell culture method for the isolation and study of primary human dental pulp cells. In G. J. Seymour, M. P. Cullinan, N. C. K. Heng & P. R. Cooper (Eds.), Oral biology: Molecular techniques and applications: Methods in molecular biology (Vol. 2588). (3rd ed.) (pp. 393-405). New York, NY: Springer. doi: 10.1007/978-1-0716-2780-8_22
Chapter in Book - Research
Alsamahi, S., Milne, T. J., Hussaini, H. M., Rich, A. M., Cooper, P. R., & Friedlander, L. T. (2023). Effects of glycation end-products on the dental pulp in patients with type 2 diabetes. International Endodontic Journal, 56, 1373-1384. doi: 10.1111/iej.13966
Journal - Research Article
Friedlander, L. T., Wallace, W. D. A., Broadbent, J. M., Hanlin, S. M., Lyons, K. M., Cannon, R. D., & Cooper, P. R. (2023). Preparedness and competency of New Zealand graduates for general dental practice: Perceptions from the workforce. Australian Dental Journal. Advance online publication. doi: 10.1111/adj.12981
Journal - Research Article
Friedlander, L., Hunt, G., Chandler, N., & Daniel, B. (2023). Students' experience and perceptions of undergraduate endodontic education in New Zealand. Australian Endodontic Journal. Advance online publication. doi: 10.1111/aej.12770
Journal - Research Article
AlSamahi, S., Milne, T. J., Hussaini, H., Rich, A. M., & Friedlander, L. T. (2022). Type 2 diabetes and the clinically normal pulp: An in-vitro study. International Endodontic Journal, 55, 660-671. doi: 10.1111/iej.13732
Journal - Research Article
Arora, S., Cooper, P. R., Friedlander, L. T., Seo, B., Rizwan, S. B., Rich, A. M., & Hussaini, H. M. (2022). Potentiality and inflammatory marker expression are maintained in dental pulp cell cultures from carious teeth. International Journal of Molecular Sciences, 23(16), 9425. doi: 10.3390/ijms23169425
Journal - Research Article
Chutipongpisit, K., Parachuru, V. P., Friedlander, L. T., Hussaini, H. M., & Rich, A. M. (2021). Immunohistochemical and immunofluorescence expression profile of lymphatic endothelial cell markers in oral cancer. International Journal of Experimental Pathology, 102, 268-278. doi: 10.1111/iep.12411
Journal - Research Article
Al-Hassiny, A., Hussani, H., Milne, T., Seo, B., Rich, A. M., & Friedlander, L. T. (2019). Vascularity and angiogenic signaling in the dentine-pulp complex of immature and mature permanent teeth. European Endodontic Journal, 4(2), 80-85. doi: 10.14744/eej.2019.26349
Journal - Research Article
Friedlander, L. T., Meldrum, A. M., & Lyons, K. (2019). Curriculum development in final year dentistry to enhance competency and professionalism for contemporary general dental practice. European Journal of Dental Education, 23, 489-506. doi: 10.1111/eje.12458
Journal - Research Article
Al-Hassiny, A., Friedlander, L. T., Parachuru, V. P. B., Seo, B., Hussaini, H. M., & Rich, A. M. (2018). Upregulation of angiogenesis in oral lichen planus. Journal of Oral Pathology & Medicine, 47(2), 173-178. doi: 10.1111/jop.12665
Journal - Research Article
Friedlander, L. T., Coates, D., Seymour, G., Cullinan, M., & Rich, A. M. (2018). Vascularity and VEGF/VEGFR2 signaling in the dentine–pulp complex of immature and mature permanent teeth. European Endodontic Journal, 3(3), 153-159. doi: 10.14744/eej.2018.07269
Journal - Research Article
Russell, A. A., Chandler, N. P., & Friedlander, L. T. (2018). Crack formation following root-end preparation in roots with the butterfly effect. European Endodontic Journal, 3(2), 107-112. doi: 10.14744/eej.2018.47965
Journal - Research Article
Russell, A., Friedlander, L., & Chandler, N. (2018). Sealer penetration and adaptation in root canals with the butterfly effect. Australian Endodontic Journal, 44(3), 225-234. doi: 10.1111/aej.12238
Journal - Research Article
Russell, A. A., Chandler, N. P., & Friedlander, L. T. (2017). Vertical root fractures in root canal-treated teeth. ENDO, 11(3), 173-182.
Journal - Research Article
Firth, F. A., Friedlander, L. T., Parachuru, V. P. B., Kardos, T. B., Seymour, G. J., & Rich, A. M. (2015). Regulation of immune cells in oral lichen planus. Archives of Dermatological Research, 307, 333-339. doi: 10.1007/s00403-015-1540-8
Journal - Research Article
Friedlander, L. T., Hussaini, H., Cullinan, M. P., Seymour, G. J., De Silva, R. K., De Silva, H., Cameron, C., & Rich, A. M. (2015). VEGF and VEGFR2 in dentigerous cysts associated with impacted third molars. Pathology, 47(5), 446-451. doi: 10.1097/pat.0000000000000272
Journal - Research Article
Friedlander, L., McElroy, K., Daniel, B., Cullinan, M., & Hanlin, S. (2015). Direct pulp capping of permanent teeth in New Zealand general dental practice: A practice based research study. New Zealand Dental Journal, 111(2), 58-64.
Journal - Research Article
Alothmani, O. S., Chandler, N. P., & Friedlander, L. T. (2013). The anatomy of the root apex: A review and clinical considerations in endodontics. Saudi Endodontic Journal, 3(1), 1-9. doi: 10.4103/1658-5984.116273
Journal - Research Article
Alothmani, O. S., Friedlander, L. T., & Chandler, N. P. (2013). Radiographic assessment of endodontic working length. Saudi Endodontic Journal, 3(2), 57-64. doi: 10.4103/1658-5984.118145
Journal - Research Article
Alothmani, O. S., Friedlander, L. T., Monteith, B. D., & Chandler, N. P. (2013). Influence of clinical experience on the radiographic determination of endodontic working length. International Endodontic Journal, 46(3), 211-216. doi: 10.1111/j.1365-2591.2012.02109.x
Journal - Research Article
Lin, Y. P., Love, R. M., Friedlander, L. T., Shang, H. F., & Pai, M. H. (2013). Expression of Toll-like receptor 2 and 4, and the OPG-RANKL-RANK system in inflammatory external root resorption and external cervical resorption. International Endodontic Journal, 46, 971-981. doi: 10.1111/iej.12088
Journal - Research Article
Friedlander, L., & Anderson, V. (2011). A new predoctoral endodontic module: Evaluating learning and effectiveness. Journal of Dental Education, 75(3), 351-359.
Journal - Research Article
Friedlander, L. T., Love, R. M., & Cullinan, M. P. (2009). Dental stem cells and their potential role in apexogenesis and apexification. International Endodontic Journal, 42(11), 955-962. doi: 10.1111/j.1365-2591.2009.01622.x
Journal - Research Article
Buchanan, J., Colquhoun, A., Friedlander, L., Evans, S., Whitley, B., & Thomson, M. (2005). Maxillofacial fractures at Waikato Hospital, New Zealand: 1989 to 2000. New Zealand Medical Journal, 118(1217). Retrieved from http://journal.nzma.org.nz/journal/118-1217/1529/content.pdf
Journal - Research Article
Friedlander, L. T., Love, R. M., & Chandler, N. P. (2002). A comparision of phosphor-plate digital images with conventional radiographs for the perceived clarity of fine endodontic files and periapical lesions. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology, 93, 321-327.
Journal - Research Article
Dohan, Z., Friedlander, L. T., Cooper, P. R., Li, K.-C., Ratnayake, J. T., & Mei, M. L. (2023). In vitro models used in the formation of root caries lesions: A review of the literature. Dentistry Journal, 11, 269. doi: 10.3390/dj11120269
Journal - Research Other
Arora, S., Cooper, P. R., Ratnayake, J. T., Friedlander, L. T., Rizwan, S. B., Seo, B., & Hussaini, H. M. (2022). A critical review of in vitro research methodologies used to study mineralization in human dental pulp cell cultures. International Endodontic Journal, 55(Suppl. 1), 3-13. doi: 10.1111/iej.13684
Journal - Research Other
Arora, S., Cooper, P. R., Friedlander, L. T., Rizwan, S., Seo, B., Rich, A. M., & Hussaini, H. M. (2021). Potential application of immunotherapy for modulation of pulp inflammation: Opportunities for vital pulp treatment. International Endodontic Journal, 54, 1263-1274. doi: 10.1111/iej.13524
Journal - Research Other
Sadr, A., Rossi-Fedele, G., Love, R. M., George, R., Parashos, P., Wu, M. C.-Y., Friedlander, L., … Abbott, P. V. (2021). Revised guidelines for the endodontic education of dentistry students in Australia and New Zealand (FEBRUARY 2021). Australian Endodontic Journal, 47, 327-331. doi: 10.1111/aej.12501
Journal - Research Other
Coates, D. E., Alansary, M., Friedlander, L., Zanicotti, D. G., & Duncan, W. J. (2020). Dental pulp stem cells in serum-free medium for regenerative medicine. Journal of the Royal Society of New Zealand, 50(1), 80-90. doi: 10.1080/03036758.2019.1673447
Journal - Research Other
Rossi-Fedele, G., Damiani, F., Love, R. M., George, R., Parashos, P., Wu, M. C.-Y., Friedlander, L., … Abbott, P. V. (2020). Revised guidelines for educational requirements for specialisation in endodontics in Australia and New Zealand (July 2020). Australian Endodontic Journal, 46, 302-306. doi: 10.1111/aej.12431
Journal - Research Other
Friedlander, L. T., Chandler, N. P., & Drummond, B. K. (2013). Avulsion and replantation of a primary incisor tooth. Dental Traumatology, 29(6), 494-497. doi: 10.1111/j.1600-9657.2012.01168.x
Journal - Research Other
Friedlander, L., Chandler, N., & Love, R. (2011). Periapical healing following combined non-surgical and surgical retreatments [Case report]. ENDO, 5(1), 27-34.
Journal - Research Other