Email mark.lokman@stonebow.otago.ac.nz
Tel 64 3 479 5846
Fax 64 3 479 7584
Publications:
Dr Lokman's publications are available here
Teaching:
Research Interests:
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Endocrine control of previtellogenic oocyte growth
There is a substantial change in size and appearance of oocytes during the early growth phase, known as previtellogenesis. Very little is known about the endocrine mechanisms controlling this growth phase. Our findings on the involvement of androgens and insulin-like growth factor-I in controlling previtellogenesis in eel in vitro are a world-first step to address this issue. The mechanisms by which androgens and IGF-I mediate their actions are currently investigated.
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Mechanisms controlling fecundity in fish
It is well-known that nutrition can dramatically affect fecundity in fish. However, little is known about how this is controlled. We are currently developing molecular tools to shed light on this phenomenon, using eel and goldfish as models.
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Evolution of vertebrate endocrine systems
Echinoderms are the closest sister taxa to the chordates. Both deuterostome groups produce steroids, the function of which is particularly well-studied in vertebrates. However, little is known about steroid action and the control of steroid biosynthesis in echinoderms – research is currently being conducted to address these issues.
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Growth and reproduction of aquaculture species in NZ
Aquaculture contributes significantly to the harvest of aquatic products, both globally and in New Zealand. I have been incorporating my interests in aquaculture into some of the research projects and applied contracts in my laboratory in recent years.
Current issues (potential research projects) in the NZ aquaculture industry include:
- full artificial control of abalone reproduction
- interaction between growth and reproduction in salmon
- pharmacology and application of slow-release GnRH preparations in salmon
- development of farming methods for new aquaculture species
Postgraduate Students
- Sean Divers (MSc) - Lipase and lipid mobilization in eel
- Michael Algie (MSc) – androgen action in eel
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