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Associate Professor Mark Lokman

Email mark.lokman@otago.ac.nz

Phone 64-3-479-5846

Mark-Lokman

Teaching

Research Interests

  • Endocrine control of previtellogenic oocyte growth
  • Mechanisms controlling fecundity in fish
  • Evolution of vertebrate endocrine systems
  • Growth and reproduction of aquaculture species in NZ
  • Developmental Genetics

Current issues (potential research projects) in the NZ aquaculture industry include:
1. full artificial control of abalone reproduction
2. interaction between growth and reproduction in salmon
3. control of reproduction in eel, hapuka (groper) and giant kokopu
4. development of farming methods for new aquaculture species

Postgraduate Students

  • Erin Forbes (PhD) - effects of androgens on eel liver physiology
  • Khalid Alqaisi (PhD) - evolution of steroidogenesis in starfish
  • Sean Divers (PhD) - induced spawning of eel
  • Yair Kohn (PhD) - oogenesis and egg quality in hapuka
  • Ali Falahati (PhD) - GDF-9 signaling in the eel ovary
  • Alireza (Hamed) Shoae (PhD) - the ovarian IGF-I system in eel
  • Sam Van der Horst (MSc) - effects of steroids on eel heaptocytes
  • Tasman Gillies (MSc) - spawning induction in abalone

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Publications

Liu, H., Todd, E. V., Lokman, M. P., Lamm, M. S., Godwin, J. R., & Gemmell, N. J. (2017). Sexual plasticity: A fishy tale. Molecular Reproduction & Development, 84(2), 171-194. doi: 10.1002/mrd.22691

Thomson-Laing, G., Jasoni, C. L., & Lokman, P. M. (2017). The effects of migratory stage and 11-ketotestosterone on the expression of rod opsin genes in the shortfinned eel (Anguilla australis). General & Comparative Endocrinology. Advance online publication. doi: 10.1016/j.ygcen.2017.06.025

Di Biase, A., Lokman, P. M., Govoni, N., Casalini, A., Emmanuele, P., Parmeggiani, A., & Mordenti, O. (2017). Co-treatment with androgens during artificial induction of maturation in female eel, Anguilla anguilla: Effects on egg production and early development. Aquaculture. Advance online publication. doi: 10.1016/j.aquaculture.2017.06.030

Wylie, M. J., Setiawan, A. N., Irvine, G. W., Symonds, J. E., Elizur, A., Dos Santos, M., & Lokman, P. M. (2017). Ovarian development of captive F1 wreckfish (hāpuku) Polyprion oxygeneios under constant and varying temperature regimes: Implications for broodstock management. General & Comparative Endocrinology. Advance online publication. doi: 10.1016/j.ygcen.2017.08.022

Wylie, M. J., Setiawan, A. N., Irvine, G. W., Symonds, J. E., Elizur, A., & Lokman, P. M. (2017). Effects of neuropeptides and sex steroids on the pituitary-gonadal axis of pre-pubertal F1 wreckfish (hāpuku) Polyprion oxygeneios in vivo: Evidence of inhibitory effects of androgens. General & Comparative Endocrinology. Advance online publication. doi: 10.1016/j.ygcen.2017.08.018

Chapter in Book - Research

Young, G., Kusakabe, M., Nakamura, I., Lokman, P. M., & Goetz, F. W. (2005). Gonadal steroidogenesis in teleost fish. In P. Melamed & N. Sherwood (Eds.), Molecular aspects of fish and marine biology (vol. 4): Hormones and their receptors in fish reproduction. (pp. 155-223). Singapore: World Scientific.

Lokman, P. M., Rohr, D. H., Davie, P. S., & Young, G. (2003). The physiology of silvering in anguillid eels: Androgens and control of metamorphosis from the yellow to silver stage. In K. Aida, K. Tsukamoto & K. Yamauchi (Eds.), Eel biology. (pp. 331-349). Tokyo: Springer.

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Journal - Research Article

Liu, H., Todd, E. V., Lokman, M. P., Lamm, M. S., Godwin, J. R., & Gemmell, N. J. (2017). Sexual plasticity: A fishy tale. Molecular Reproduction & Development, 84(2), 171-194. doi: 10.1002/mrd.22691

Wylie, M. J., Setiawan, A. N., Irvine, G. W., Symonds, J. E., Elizur, A., & Lokman, P. M. (2017). Effects of neuropeptides and sex steroids on the pituitary-gonadal axis of pre-pubertal F1 wreckfish (hāpuku) Polyprion oxygeneios in vivo: Evidence of inhibitory effects of androgens. General & Comparative Endocrinology. Advance online publication. doi: 10.1016/j.ygcen.2017.08.018

Wylie, M. J., Setiawan, A. N., Irvine, G. W., Symonds, J. E., Elizur, A., Dos Santos, M., & Lokman, P. M. (2017). Ovarian development of captive F1 wreckfish (hāpuku) Polyprion oxygeneios under constant and varying temperature regimes: Implications for broodstock management. General & Comparative Endocrinology. Advance online publication. doi: 10.1016/j.ygcen.2017.08.022

Di Biase, A., Lokman, P. M., Govoni, N., Casalini, A., Emmanuele, P., Parmeggiani, A., & Mordenti, O. (2017). Co-treatment with androgens during artificial induction of maturation in female eel, Anguilla anguilla: Effects on egg production and early development. Aquaculture. Advance online publication. doi: 10.1016/j.aquaculture.2017.06.030

Thomson-Laing, G., Jasoni, C. L., & Lokman, P. M. (2017). The effects of migratory stage and 11-ketotestosterone on the expression of rod opsin genes in the shortfinned eel (Anguilla australis). General & Comparative Endocrinology. Advance online publication. doi: 10.1016/j.ygcen.2017.06.025

Lokman, P. M., Damsteegt, E. L., Wallace, J., Downes, M., Goodwin, S. L., Facoory, L. J., & Wylie, M. J. (2016). Dose-responses of male silver eels, Anguilla australis, to human chorionic gonadotropin and 11-ketotestosterone in vivo. Aquaculture, 463, 97-105. doi: 10.1016/j.aquaculture.2016.05.009

Setiawan, A. N., Muncaster, S., Pether, S., King, A., Irvine, G. W., Lokman, P. M., & Symonds, J. E. (2016). The effects of gonadotropin-releasing hormone analog on yellowtail kingfish Seriola lalandi (Valenciennes, 1833) spawning and egg quality. Aquaculture Reports, 4, 1-9. doi: 10.1016/j.aqrep.2016.05.001

Damsteegt, E. L., Ozaki, Y., McCormick, S. P. A., & Lokman, P. M. (2016). Triacylglyceride physiology in the shortfinned eel, Anguilla australis: The effects of androgen. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 310, R422-R431. doi: 10.1152/ajpregu.00149.2015

Di Biase, A., Casalini, A., Emmanuele, P., Mandelli, M., Lokman, P. M., & Mordenti, O. (2016). Controlled reproduction in Anguilla anguilla (L.): Comparison between spontaneous spawning and stripping-insemination approaches. Aquaculture Research, 47(10), 3052-3060. doi: 10.1111/are.12755

Alqaisi, K. M., Lamare, M. D., Grattan, D. R., Damsteegt, E. L., Schneider, W. J., & Lokman, P. M. (2016). A comparative study of vitellogenesis in Echinodermata: Lessons from the sea star. Comparative Biochemistry & Physiology Part A, 198, 72-86. doi: 10.1016/j.cbpa.2016.04.013

Wylie, M. J., Closs, G. P., Damsteegt, E. L., & Lokman, P. M. (2016). Effects of salinity and temperature on artificial cultivation and early ontogeny of giant kokopu, Galaxias argenteus (Gmelin 1789). Aquaculture Research, 47(5), 1472-1480. doi: 10.1111/are.12605

Damsteegt, E. L., McHugh, N., & Lokman, P. M. (2016). Storage by lyophilization: Resulting RNA quality is tissue dependent. Analytical Biochemistry, 511, 92-96. doi: 10.1016/j.ab.2016.08.005

Senior, A. M., Lokman, M. P., Closs, G. P., & Nakagawa, S. (2015). Ecological and evolutionary applications for environmental sex reversal of fish. Quarterly Review of Biology, 90(1), 23-44. doi: 10.1086/679762

Akhavan, S. R., Falahatkar, B., Tolouei Gilani, M. H., & Lokman, P. M. (2015). Effects of estradiol-17β implantation on growth rate, ovarian growth, sex steroid levels and vitellogenin proxies in previtellogenic sturgeon Huso huso. Animal Reproduction Science, 157, 1-10. doi: 10.1016/j.anireprosci.2014.12.010

Lokman, P. M., Wylie, M. J., Downes, M., Di Biase, A., & Damsteegt, E. L. (2015). Artificial induction of maturation in female silver eels, Anguilla australis: The benefits of androgen pre-treatment. Aquaculture, 437, 1111-1119. doi: 10.1016/j.aquaculture.2014.11.026

Damsteegt, E. L., Falahatimarvast, A., McCormick, S. P. A., & Lokman, P. M. (2015). Triacylglyceride physiology in the short-finned eel, Anguilla australis: Changes throughout early oogenesis. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 308(11), R935-R944. doi: 10.1152/ajpregu.00436.2014

Zadmajid, V., Falahatimarvast, A., Damsteegt, E. L., Setiawan, A. N., Ozaki, Y., Shoae, A., & Lokman, P. M. (2015). Effects of 11-ketotestosterone and temperature on inhibin subunit mRNA levels in the ovary of the shortfinned eel, Anguilla australis. Comparative Biochemistry & Physiology Part B, 187, 14-21. doi: 10.1016/j.cbpb.2015.04.012

Kohn, Y. Y., Symonds, J. E., Kleffmann, T., Nakagawa, S., Lagisz, M., & Lokman, P. M. (2015). Proteomic analysis of early-stage embryos: Implications for egg quality in hapuku (Polyprion oxygeneios). Fish Physiology & Biochemistry, 41(6), 1403-1417. doi: 10.1007/s10695-015-0095-0

Johnson, S. L., Villarroel, M., Rosengrave, P., Carne, A., Kleffmann, T., Lokman, P. M., & Gemmell, N. J. (2014). Proteomic analysis of Chinook salmon (Oncorhynchus tshawytscha) ovarian fluid. PLoS ONE, 9(8), e104155. doi: 10.1371/journal.pone.0104155

Akbaripasand, A., Ramezani, J., Lokman, P. M., & Closs, G. P. (2014). Does social status within a dominance hierarchy mediate individual growth, residency and relocation? Oecologia, 176(3), 771-779. doi: 10.1007/s00442-014-3038-z

Damsteegt, E. L., Mizuta, H., Ozaki, Y., Hiramatsu, N., Todo, T., Hara, A., … Lokman, P. M. (2014). Development and partial characterisation of an antiserum against apolipoprotein B of the short-finned eel, Anguilla australis. Journal of Comparative Physiology B, 184(5), 589-599. doi: 10.1007/s00360-014-0821-4

Akbaripasand, A., Ramezani, J., Lokman, P. M., & Closs, G. P. (2014). Can drifting invertebrates meet the energy requirements of drift-feeding fish? A Case Study on Galaxias fasciatus. Freshwater Science, 33(3), 904-914. doi: 10.1086/676957

Lokman, P. M., & Symonds, J. E. (2014). Molecular and biochemical tricks of the research trade: -omics approaches in finfish aquaculture. New Zealand Journal of Marine & Freshwater Research, 48(3), 492-505. doi: 10.1080/00288330.2014.928333

Wylie, M. J., Forbes, E. L., & Lokman, P. M. (2013). Ovarian biopsy: A non-terminal method to determine reproductive status in giant kokopu, Galaxias argenteus (Gmelin 1789). New Zealand Veterinary Journal, 61(5), 292-296. doi: 10.1080/00480169.2012.740657

Kohn, Y. Y., Symonds, J. E., & Lokman, P. M. (2013). The effects of 11-ketotestosterone on ovarian physiology of previtellogenic captive hapuku (Polyprion oxygeneios). Comparative Biochemistry & Physiology Part A, 166(3), 496-502. doi: 10.1016/j.cbpa.2013.07.032

Kohn, Y. Y., Lokman, P. M., Kilimnik, A., & Symonds, J. E. (2013). Sex identification in captive hapuku (Polyprion oxygeneios) using ultrasound imagery and plasma levels of vitellogenin and sex steroids. Aquaculture, 384-387, 87-93. doi: 10.1016/j.aquaculture.2012.12.020

Ghosh, R., Lokman, P. M., Lamare, M. D., Metcalf, V. J., Burritt, D. J., Davison, W., & Hageman, K. J. (2013). Changes in physiological responses of an Antarctic fish, the emerald rock cod (Trematomus bernacchii), following exposure to polybrominated diphenyl ethers (PBDEs). Aquatic Toxicology, 128-129, 91-100. doi: 10.1016/j.aquatox.2012.11.019

Reid, P. M., Divers, S. L., Zadmajid, V., Alqaisi, K. M., & Lokman, P. M. (2013). Steroidogenic acute regulatory protein transcript abundance in the eel, Anguilla australis: Changes during the induced reproductive cycle and effects of follicle-stimulating hormone during previtellogenesis. Journal of Steroid Biochemistry & Molecular Biology, 138, 464-470. doi: 10.1016/j.jsbmb.2013.02.003

Setiawan, A. N., Ozaki, Y., Shoae, A., Kazeto, Y., & Lokman, P. M. (2012). Androgen-specific regulation of FSH signalling in the previtellogenic ovary and pituitary of the New Zealand shortfinned eel, Anguilla australis. General & Comparative Endocrinology, 176(2), 132-143. doi: 10.1016/j.ygcen.2011.12.041

Setiawan, A. N., Wylie, M. J., Forbes, E. L., & Lokman, P. M. (2012). The effects of 11-ketotestosterone on occupation of downstream location and seawater in the New Zealand shortfinned eel, Anguilla australis. Zoological Science, 29(1), 1-5. doi: 10.2108/zsj.29.1

Falahatimarvast, A., Poorbagher, H., & Lokman, P. M. (2012). The reproductive biology of Pomadasys kaakan (Osteichthyes: Haemulidae) in the northern Persian Gulf. Cahiers de Biologie Marine, 53(1), 25-34.

Nafisi Bahabadi, M., Shoae, A., & Lokman, P. M. (2011). Effects of storage time, sex steroids and media composition on egg viability of rainbow trout (Oncorhynchus mykiss). Aquaculture, 315(3-4), 306-311. doi: 10.1016/j.aquaculture.2011.02.026

Endo, T., Todo, T., Lokman, P. M., Kudo, H., Ijiri, S., Adachi, S., & Yamauchi, K. (2011). Androgens and very low density lipoprotein are essential for the growth of previtellogenic oocytes from Japanese eel, Anguilla japonica, in vitro. Biology of Reproduction, 84(4), 816-825. doi: 10.1095/biolreprod.110.087163

Akbaripasand, A., Nichol, E. C., Lokman, P. M., & Closs, G. P. (2011). Microhabitat use of a native New Zealand galaxiid fish, Galaxias fasciatus. New Zealand Journal of Marine & Freshwater Research, 45(1), 135-144. doi: 10.1080/00288330.2010.544044

Cahill, P. L., Hurd, C. L., & Lokman, M. (2010). Keeping the water clean: Seaweed biofiltration outperforms traditional bacterial biofilms in recirculating aquaculture. Aquaculture, 306, 153-159. doi: 10.1016/j.aquaculture.2010.05.032

Forbes, E. L., Preston, C. D., & Lokman, P. M. (2010). Zebrafish (Danio rerio) and the egg size versus egg number trade off: Effects of ration size on fecundity are not mediated by orthologues of the Fec gene. Reproduction, Fertility & Development, 22(6), 1015-1021. doi: 10.1071/RD09257

Divers, S. L., McQuillan, H. J., Matsubara, H., Todo, T., & Lokman, P. M. (2010). Effects of reproductive stage and 11-ketotestosterone on LPL mRNA levels in the ovary of the shortfinned eel. Journal of Lipid Research, 51, 3250-3258. doi: 10.1194/jlr.M009027

Setiawan, A. N., & Lokman, P. M. (2010). The use of reference gene selection programs to study the silvering transformation in a freshwater eel Anguilla australis: A cautionary tale. BMC Molecular Biology, 11, 75. doi: 10.1186/1471-2199-11-75

Tosaka, R., Todo, T., Kazeto, Y., Lokman, P. M., Ijiri, S., Adachi, S., & Yamauchi, K. (2010). Expression of androgen receptor mRNA in the ovary of Japanese eel, Anguilla japonica, during artificially induced ovarian development. General & Comparative Endocrinology, 168, 424-430. doi: 10.1016/j.ygcen.2010.05.005

Lokman, P. M., Kazeto, Y., Ozaki, Y., Ijiri, S., Tosaka, R., Kohara, M., … Divers, S. L., … Adachi, S. (2010). Effects of reproductive stage, GH, and 11-ketotestosterone on expression of growth differentiation factor-9 in the ovary of the eel, Anguilla australis. Reproduction, 139(1), 71-83. doi: 10.1530/REP-08-0454

Kristensen, P. B., Closs, G. P., Lokman, P. M., & Grønkjær, P. (2008). Otolith formation, microstructure and daily increment validation in juvenile perch Perca fluviatilis. Journal of Fish Biology, 73(6), 1478-1483. doi: 10.1111/j.1095-8649.2008.02019.x

Setiawan, A. N., Davis, L. S., Darby, J. T., Lokman, P. M., Young, G., Blackberry, M. A., … Martin, G. B. (2007). Effects of artificial social stimuli on the reproductive schedule and hormone levels of yellow-eyed penguins (Megadyptes antipodes). Hormones & Behavior, 51, 46-53.

Wright, K. A., Woods, C. M. C., Gray, B. E., & Lokman, P. M. (2007). Recovery from acute, chronic and transport stress in the pot-bellied seahorse Hippocampus abdominalis. Journal of Fish Biology, 70, 1447-1457.

Lokman, P. M., George, K. A. N., Divers, S. L., Algie, M., & Young, G. (2007). 11-Ketotestosterone and IGF-I increase the size of previtellogenic oocytes from shortfinned eel, Anguilla australis, in vitro. Reproduction, 133, 955-967.

Harwood, N. J., & Lokman, P. M. (2006). Fecundity of banded wrasse (Notolabrus fucicola) from Otago, Southern New Zealand. New Zealand Journal of Marine & Freshwater Research, 40(3), 467-476. doi: 10.1080/00288330.2006.9517436

Searle, T., Roberts, R. D., & Lokman, P. M. (2006). Effects of temperature on growth of juvenile blackfoot abalone, Haliotis iris Gmelin. Aquaculture Research, 37, 1441-1449.

Hammond, K. S., Hollows, J. W., Townsend, C. R., & Lokman, P. M. (2006). Effects of temperature and water calcium concentration on growth, survival and moulting of freshwater crayfish, Paranephrops zealandicus. Aquaculture, 251, 271-279.

Setiawan, A. N., Davis, L. S., Darby, J. T., Lokman, P. M., Young, G., Blackberry, M. A., … Martin, G. B. (2006). Hormonal correlates of parental behavior in yellow-eyed penguins (Megadyptes antipodes). Comparative Biochemistry & Physiology Part A, 145, 357-362.

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