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Health Sciences staff profiles

Professor George Dias

PositionProfessor
DepartmentDepartment of Anatomy
QualificationsBDS (S Lanka) MS (Dental Surgery), PhD (Otago), Specialist in Dental Surgery PGIM (Colombo)
Research summaryBiomaterials, clinical anatomy and forensic science

Research

The main areas of interest are:

  1. A new bone substitute – currently used bone substitutes eg porous ceramics, hydroxyapatite, metals, and polymers (polylactic acid-polyglycolic acid) have certain disadvantages. Work is in progress to develop a new bone substitute from reconstituted keratin and metal alloys that are biodegradable.
  2. The overall programme goal is to create new biomedical devices combining reconstituted keratin, and a permanent material, such as titanium. The composite devices will create new opportunities for the use in dental and maxillo facial surgery and large bone/joint replacement or reconstruction in orthopedic surgery.
  3. This project will carry out in vitro and in vivo investigations to study the morphological and biological properties of TBC.
  4. Detailed anatomy – Work is in progress to investigate the origin of the auriculotemporal nerve and the morphology of the lateral pterygoid muscle.
  5. Work is in progress to improve the method of facial reconstruction on the skull in the field of forensics and archeology.

The work described in (a) and (b) is being carried out in collaboration with the Canesis Network Ltd and Dr Mark Staiger, University of Canterbury. The work described in (c) is carried out in collaboration with Dr Michael Mucalo, University of Waikato.

Publications

Dias, G. J., Mahoney, P., Hung, N. A., Sharma, L. A., Kalita, P., Smith, R. A., … Ali, A. (2017). Osteoconduction in keratin-hydroxyapatite composite bone-graft substitutes. Journal of Biomedical Materials Research Part B, 105(7), 2034-2044. doi: 10.1002/jbm.b.33735

Ratnayake, J. T. B., Gould, M. L., Shavandi, A., Mucalo, M., & Dias, G. J. (2017). Development and characterization of a xenograft material from New Zealand sourced bovine cancellous bone. Journal of Biomedical Materials Research Part B, 105(5), 1054-1062. doi: 10.1002/jbm.b.33644

Ajay Sharma, L., Ali, M. A., Love, R. M., Wilson, M. J., & Dias, G. J. (2016). Novel keratin preparation supports growth and differentiation of odontoblast-like cells. International Endodontic Journal, 49(5), 471-482. doi: 10.1111/iej.12476

Walker, J., Shadanbaz, S., Woodfield, T. B. F., Staiger, M. P., & Dias, G. J. (2014). The in vitro and in vivo evaluation of the biocompatibility of Mg alloys. Biomedical Materials, 9, 015006. doi: 10.1088/1748-6041/9/1/015006

Laird, D. F., Mucalo, M. R., & Dias, G. J. (2012). Vacuum-assisted infiltration of chitosan or polycaprolactone as a structural reinforcement for sintered cancellous bovine bone graft. Journal of Biomedical Materials Research Part A, 100A(10), 2581-2592. doi: 10.1002/jbm.a.34193

Journal - Research Article

Ratnayake, J. T. B., Gould, M. L., Shavandi, A., Mucalo, M., & Dias, G. J. (2017). Development and characterization of a xenograft material from New Zealand sourced bovine cancellous bone. Journal of Biomedical Materials Research Part B, 105(5), 1054-1062. doi: 10.1002/jbm.b.33644

Dias, G. J., Mahoney, P., Hung, N. A., Sharma, L. A., Kalita, P., Smith, R. A., … Ali, A. (2017). Osteoconduction in keratin-hydroxyapatite composite bone-graft substitutes. Journal of Biomedical Materials Research Part B, 105(7), 2034-2044. doi: 10.1002/jbm.b.33735

Ajay Sharma, L., Ali, M. A., Love, R. M., Wilson, M. J., & Dias, G. J. (2016). Novel keratin preparation supports growth and differentiation of odontoblast-like cells. International Endodontic Journal, 49(5), 471-482. doi: 10.1111/iej.12476

Macari, S., Duffles, L. F., Queiroz-Junior, C. M., Madeira, M. F. M., Dias, G. J., Teixeira, M. M., … Silva, T. A. (2015). Oestrogen regulates bone resorption and cytokine production in the maxillae of female mice. Archives of Oral Biology, 60(2), 333-341. doi: 10.1016/j.archoralbio.2014.11.010

Dias, G. J., Lal, N., Chandrasekera, M., & Cornwall, J. (2015). Identification of the posterior deep temporal nerve groove and canal, and its relationship to basicranial angle. Anatomical Science International, 90(4), 256-263. doi: 10.1007/s12565-014-0260-z

Dias, G. J., de Silva, R. K., Shah, T., Sim, E., Song, N., Colombage, S., & Cornwall, J. (2015). Multivariate assessment of site of lingual nerve. British Journal of Oral & Maxillofacial Surgery, 53(4), 347-351. doi: 10.1016/j.bjoms.2015.01.011

Ajay Sharma, L., Sharma, A., & Dias, G. J. (2015). Advances in regeneration of dental pulp: A literature review. Journal of Investigative & Clinical Dentistry, 6(2), 85-98. doi: 10.1111/jicd.12064

Dias, G. J., Koh, J. M. C., & Cornwall, J. (2015). The origin of the auriculotemporal nerve and its relationship to the middle meningeal artery. Anatomical Science International, 90(4), 216-221. doi: 10.1007/s12565-014-0247-9

Shadanbaz, S., Walker, J., Woodfield, T. B. F., Staiger, M. P., & Dias, G. J. (2014). Monetite and brushite coated magnesium: In vivo and in vitro models for degradation analysis. Journal of Materials Science: Materials in Medicine, 25(1), 173-183. doi: 10.1007/s10856-013-5059-2

Dias, G. J., Perumal, V., Smith, C., & Cornwall, J. (2014). The relationship between jugular foramen asymmetry and superior sagittal venous sinus laterality. Anthropological Science, 122(2), 115-120. doi: 10.1537/ase.140615

Walker, J., Shadanbaz, S., Woodfield, T. B. F., Staiger, M. P., & Dias, G. J. (2014). Magnesium biomaterials for orthopedic application: A review from a biological perspective. Journal of Biomedical Materials Research Part B, 102(6), 1316-1331. doi: 10.1002/jbm.b.33113

Rongo, R., Antoun, J. S., Lim, Y. X., Dias, G., Valletta, R., & Farella, M. (2014). Three-dimensional evaluation of the relationship between jaw divergence and facial soft tissue dimensions. Angle Orthodontist, 84(5), 788-794. doi: 10.2319/092313-699.1

Antoun, J. S., Lawrence, C., Leow, A., Rongo, R., Dias, G., & Farella, M. (2014). A three-dimensional evaluation of Māori and New Zealand European faces. Australian Orthodontic Journal, 30(2), 169-175.

Walker, J., Shadanbaz, S., Woodfield, T. B. F., Staiger, M. P., & Dias, G. J. (2014). The in vitro and in vivo evaluation of the biocompatibility of Mg alloys. Biomedical Materials, 9, 015006. doi: 10.1088/1748-6041/9/1/015006

Shadanbaz, S., Walker, J., Staiger, M. P., Dias, G. J., & Pietak, A. (2013). Growth of calcium phosphates on magnesium substrates for corrosion control in biomedical applications via immersion techniques. Journal of Biomedical Materials Research Part B, 101B(1), 162-172. doi: 10.1002/jbm.b.32830

Cooper, K., Bennani, V., Tawse-Smith, A., Reid, M., Stirling, C., & Dias, G. (2013). Effect of a cordless retraction paste on titanium surface: A topographic, chemical and biocompatibility evaluation. Brazilian Oral Research, 27(3), 211-217.

Laird, D. F., Mucalo, M. R., & Dias, G. J. (2012). Vacuum-assisted infiltration of chitosan or polycaprolactone as a structural reinforcement for sintered cancellous bovine bone graft. Journal of Biomedical Materials Research Part A, 100A(10), 2581-2592. doi: 10.1002/jbm.a.34193

Waterman, J., Birbilis, N., Dias, G. J., Woodfield, T. B. F., & Staiger, M. P. (2012). Improving in vitro corrosion resistance of biomimetic calcium phosphate coatings for Mg substrates using calcium hydroxide layer. Corrosion Engineering, Science & Technology, 47(5), 340-345. doi: 10.1179/1743278212y.0000000018

Nguyen, T. L., Blanquet, A., Staiger, M. P., Dias, G. J., & Woodfield, T. B. F. (2012). On the role of surface roughness in the corrosion of pure magnesium in vitro. Journal of Biomedical Materials Research Part B, 100 B(5), 1310-1318.

Shadanbaz, S., & Dias, G. J. (2012). Calcium phosphate coatings on magnesium alloys for biomedical applications: A review. Acta Biomaterialia, 8, 20-30. doi: 10.1016/j.actbio.2011.10.016

Walker, J., Shadanbaz, S., Kirkland, N. T., Stace, E., Woodfield, T., Staiger, M. P., & Dias, G. J. (2012). Magnesium alloys: Predicting in vivo corrosion with in vitro immersion testing. Journal of Biomedical Materials Research Part B, 100B(4), 1134-1141. doi: 10.1002/jbm.b.32680

Kirkland, N. T., Waterman, J., Birbilis, N., Dias, G., Woodfield, T. B. F., Hartshorn, R. M., & Staiger, M. P. (2012). Buffer-regulated biocorrosion of pure magnesium. Journal of Materials Science: Materials in Medicine, 23, 283-291. doi: 10.1007/s10856-011-4517-y

Dias, G. J., Cook, R. B., & Mirhosseini, M. (2011). Influence of food consistency on growth and morphology of the mandibular condyle. Clinical Anatomy, 24(5), 590-598. doi: 10.1002/ca.21122

Nguyen, T. L., Staiger, M. P., Dias, G. J., & Woodfield, T. B. F. (2011). A novel manufacturing route for fabrication of topologically-ordered porous magnesium scaffolds. Advanced Engineering Materials, 13(9), 872-881. doi: 10.1002/adem.201100029

Kirkland, N. T., Kolbeinsson, I., Woodfield, T., Dias, G. J., & Staiger, M. P. (2011). Synthesis and properties of topologically ordered porous magnesium. Materials Science & Engineering: B, 176(20), 1666-1672. doi: 10.1016/j.mseb.2011.04.006

Waterman, J., Pietak, A., Birbilis, N., Woodfield, T., Dias, G., & Staiger, M. P. (2011). Corrosion resistance of biomimetic calcium phosphate coatings on magnesium due to varying pretreatment time. Materials Science & Engineering: B, 176(20), 1756-1760. doi: 10.1016/j.mseb.2011.06.021

Staiger, M. P., Kolbeinsson, I., Kirkland, N. T., Nguyen, T., Dias, G., & Woodfield, T. B. F. (2010). Synthesis of topologically-ordered open-cell porous magnesium. Materials Letters, 64(23), 2572-2574. doi: 10.1016/j.matlet.2010.08.049

Oskam, C. L., Premachandra, I. M., & Dias, G. J. (2010). Bizygomatic breadth determination in damaged skulls. International Journal of Osteoarchaeology, 20(5), 540-548. doi: 10.1002/oa.1087

Dias, G. J., Peplow, P. V., McLaughlin, A., Teixeira, F., & Kelly, R. J. (2010). Biocompatibility and osseointegration of reconstituted keratin in an ovine model. Journal of Biomedical Materials Research Part A, 92A(2), 513-520. doi: 10.1002/jbm.a.32394

Ghosh, A., Ali, M. A., Selvanesan, L., & Dias, G. J. (2010). Structure-function characteristics of the biomaterials based on milk-derived proteins. International Journal of Biological Macromolecules, 46, 404-411. doi: 10.1016/j.ijbiomac.2010.02.011

Dias, G. J., Mahoney, P., Swain, M., Kelly, R. J., Smith, R. A., & Ali, M. A. (2010). Keratin-hydroxyapatite composites: Biocompatibility, osseointegration, and physical properties in an ovine model. Journal of Biomedical Materials Research Part A, 95A(4), 1084-1095. doi: 10.1002/jbm.a.32908

Kirkland, N. T., Birbilis, N., Walker, J., Woodfield, T., Dias, G. J., & Staiger, M. P. (2010). In-vitro dissolution of magnesium-calcium binary alloys: Clarifying the unique role of calcium additions in bioresorbable magnesium implant alloys. Journal of Biomedical Materials Research Part B, 95B(1), 91-100. doi: 10.1002/jbm.b.31687

Ghosh, A., Ali, M. A., & Dias, G. J. (2009). Effect of cross-linking on microstructure and physical performance of casein protein. Biomacromolecules, 10(7), 1681-1688. doi: 10.1021/bm801341x

Wasterlain, S. N., & Dias, G. J. (2009). Amelogenesis imperfecta in an early 20th century population from central Portugal. International Journal of Osteoarchaeology, 19(3), 424-435. doi: 10.1002/oa.972

Peplow, P. V., Dias, G. J., Teixeira, F., & Kelly, R. J. (2009). Tissue reaction to matrices of reconstituted keratin polymer implanted subcutaneously in sheep. Journal of Biomedical Materials Research Part A, 89A(1), 255-265. doi: 10.1002/jbm.a.32038

Pietak, A., Mahoney, P., Dias, G. J., & Staiger, M. P. (2008). Bone-like matrix formation on magnesium and magnesium alloys. Journal of Materials Science: Materials in Medicine, 19(1), 407-415. doi: 10.1007/s10856-007-3172-9

Dennison, J., Mahoney, P., Herbison, P., & Dias, G. (2008). The false and the true bifid condyles. HOMO, 59, 149-159. doi: 10.1016/j.jchb.2008.02.001

Dias, G. J., Prasad, K., & Santos, A. L. (2007). Pathogenesis of apical periodontal cysts: Guidelines for diagnosis in palaeopathology. International Journal of Osteoarchaeology, 17, 619-626.

Dennison, K. J., & Dias, G. J. (2007). The posterior deep temporal nerve: Its relationship with the human cranial base. Clinical Anatomy, 20(2), 126-130.

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