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Health Sciences staff profiles

Dr Johann Zwirner

PositionLecturer
DepartmentDepartment of Anatomy
QualificationsMD Dr (med)
Research summaryBiomechanics, forensics and surgically-relevant anatomy

Research

Johann is a trained medical doctor who originally joined the department on a one year mission to refine laparoscopic approaches to deep pelvic structures. As Dunedin was too beautiful to leave after this short time, he continued working on this project which developed into exploring the role of deep pelvic structures as attachment points for incontinence surgery.

Surrounded by an outstanding team in Otago, Johann’s main research focus is now the mechanical characterisation of tissue layers of the human head. His research helps to obtain fundamental material parameters applicable to virtual reality simulators used in surgery, and the design of realistic human head models to be used in forensic pathology.

Together with a diverse team of national and international collaborators, Johann works on a number of other clinically relevant anatomical topics such as the:

  • Biomechanical role of fat in various body parts
  • Influence of chemical treatments on the biomechanical behaviour of human tissues
  • Biomechanical role of the calcaneus in force transmission between the calf and the foot

Johann uses a wide range of imaging techniques such as:

  • Computed Tomography
  • Digital Image Correlation (simultaneous with biomechanical tests)
  • Light Microscopy
  • Magnetic Resonance Imaging
  • Scanning Electron Microscopy
  • 3D-Scanning

Johann combines imaging techniques with various methods to learn about the biomechanical behavior of human tissues:

  • Atomic Force Microscopy (additionally used for imaging)
  • Nano Indenting
  • Universal Testing Machines running in both tensile and compressive modes

Publications

Poilliot, A., Tannock, M., Zhang, M., Zwirner, J., & Hammer, N. (2020). Quantification of fat in the posterior sacroiliac joint region applying a semi-automated segmentation method. Computer Methods & Programs in Biomedicine, 191, 105386. doi: 10.1016/j.cmpb.2020.105386

Ondruschka, B., König, C. J., Zwirner, J., & Bayer, R. (2020). Forensische untersuchung und spurensicherung bei sexualdelikten: Schritt für schritt [Forensic investigation and identification in sexual assaults: Step by step]. Frauenheilkunde up2date, 14(1), 15-23. doi: 10.1055/a-1069-4136

Tomlinson, J., Zwirner, J., Ondruschka, B., Prietzel, T., & Hammer, N. (2020). Innervation of the hip joint capsular complex: A systematic review of histological and immunohistochemical studies and their clinical implications for contemporary treatment strategies in total hip arthroplasty. PLoS ONE, 15(2), e0229128. doi: 10.1371/journal.pone.0229128

De Decker, A., Fergusson, R., Ondruschka, B., Hammer, N., & Zwirner, J. (2019). Anatomical structures at risk using different approaches for sacrospinous ligament fixation. Clinical Anatomy. Advance online publication. doi: 10.1002/ca.23404

Ondruschka, B., Lee, J. H. C., Scholze, M., Zwirner, J., Tong, D., Waddell, J. N., & Hammer, N. (2019). A biomechanical comparison between human calvarial bone and a skull simulant considering the role of attached periosteum and dura mater. International Journal of Legal Medicine, 133, 1603-1610. doi: 10.1007/s00414-019-02102-4

Journal - Research Article

Poilliot, A., Tannock, M., Zhang, M., Zwirner, J., & Hammer, N. (2020). Quantification of fat in the posterior sacroiliac joint region applying a semi-automated segmentation method. Computer Methods & Programs in Biomedicine, 191, 105386. doi: 10.1016/j.cmpb.2020.105386

Tomlinson, J., Zwirner, J., Ondruschka, B., Prietzel, T., & Hammer, N. (2020). Innervation of the hip joint capsular complex: A systematic review of histological and immunohistochemical studies and their clinical implications for contemporary treatment strategies in total hip arthroplasty. PLoS ONE, 15(2), e0229128. doi: 10.1371/journal.pone.0229128

Ondruschka, B., König, C. J., Zwirner, J., & Bayer, R. (2020). Forensische untersuchung und spurensicherung bei sexualdelikten: Schritt für schritt [Forensic investigation and identification in sexual assaults: Step by step]. Frauenheilkunde up2date, 14(1), 15-23. doi: 10.1055/a-1069-4136

De Decker, A., Fergusson, R., Ondruschka, B., Hammer, N., & Zwirner, J. (2019). Anatomical structures at risk using different approaches for sacrospinous ligament fixation. Clinical Anatomy. Advance online publication. doi: 10.1002/ca.23404

Ondruschka, B., Lee, J. H. C., Scholze, M., Zwirner, J., Tong, D., Waddell, J. N., & Hammer, N. (2019). A biomechanical comparison between human calvarial bone and a skull simulant considering the role of attached periosteum and dura mater. International Journal of Legal Medicine, 133, 1603-1610. doi: 10.1007/s00414-019-02102-4

Trautz, F., Franke, H., Bohnert, S., Hammer, N., Müller, W., Stassart, R., … Zwirner, J., … Ondruschka, B. (2019). Survival-time dependent increase in neuronal IL-6 and astroglial GFAP expression in fatally injured human brain tissue. Scientific Reports, 9(1), 11771. doi: 10.1038/s41598-019-48145-w

Zwirner, J., Babian, C., Ondruschka, B., Schleifenbaum, S., Scholze, M., Waddell, N. J., & Hammer, N. (2019). Tensile properties of the human iliotibial tract depend on height and weight. Medical Engineering & Physics. Advance online publication. doi: 10.1016/j.medengphy.2019.05.001

Zwirner, J., Scholze, M., Waddell, J. N., Ondruschka, B., & Hammer, N. (2019). Mechanical properties of human dura mater in tension: An analysis at an age range of 2 to 94 years. Scientific Reports, 9, 16655. doi: 10.1038/s41598-019-52836-9

Crosado, B., Löffler, S., Ondruschka, B., Zhang, M., Zwirner, J., & Hammer, N. (2019). Phenoxyethanol-based embalming for anatomy teaching: An 18-years' experience with Crosado embalming at the University of Otago in New Zealand. Anatomical Sciences Education. Advance online publication. doi: 10.1002/ase.1933

Poilliot, A., Doyle, T., Tomlinson, J., Zhang, M., Zwirner, J., & Hammer, N. (2019). Quantification of fat in the posterior sacroiliac joint region: Fat volume is sex and age dependant. Scientific Reports, 9, 14935. doi: 10.1038/s41598-019-51300-y

Zwirner, J., Ondruschka, B., Scholze, M., Schulze-Tanzil, G., & Hammer, N. (2019). Mechanical and morphological description of human acellular dura mater as a scaffold for surgical reconstruction. Journal of the Mechanical Behavior of Biomedical Materials, 96, 38-44. doi: 10.1016/j.jmbbm.2019.04.035

Zwirner, J., Scholze, M., Ondruschka, B., & Hammer, N. (2019). Tissue biomechanics of the human head are altered by Thiel embalming, restricting its use for biomechanical validation. Clinical Anatomy, 32(7), 903-913. doi: 10.1002/ca.23409

Ondruschka, B., Baier, C., Bernhard, M., Buschmann, C., Dreβler, J., Schlote, J., Zwirner, J., & Hammer, N. (2018). Frequency and intensity of pulmonary bone marrow and fat embolism due to manual or automated chest compressions during cardiopulmonary resuscitation. Forensic Science, Medicine, & Pathology. Advance online publication. doi: 10.1007/s12024-018-0044-1

Zwirner, J., Möbius, D., Bechmann, I., Arendt, T., Hoffmann, K.-T., Jäger, C., … Hammer, N. (2017). Subthalamic nucleus volumes are highly consistent but decrease age-dependently: A combined magnetic resonance imaging and stereology approach in humans. Human Brain Mapping, 38(2), 909-922. doi: 10.1002/hbm.23427

Zwirner, J., Bayer, R., Japes, A., Eplinius, F., Dreβler, J., & Ondruschka, B. (2017). Suicide by the intraoral blast of firecrackers: Experimental simulation using a skull simulant model. International Journal of Legal Medicine, 131(6), 1581-1587. doi: 10.1007/s00414-017-1580-z

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Journal - Research Other

Ondruschka, B., Babian, C., Neef, M., Zwirner, J., & Schwarz, M. (2019). Entomological and cardiologic evidence of time since death in short postmortem intervals. Journal of Forensic Sciences, 64(4), 1563-1567. doi: 10.1111/1556-4029.14010

Poilliot, A. J., Zwirner, J., Doyle, T., & Hammer, N. (2019). A systematic review of the normal sacroiliac joint anatomy and adjacent tissues for pain physicians. Pain Physician, 22(4), E247-E274. [Review].

Zwirner, J., Bayer, R., Hädrich, C., Bollmann, A., Klein, N., Dreβler, J., & Ondruschka, B. (2016). Pulmonary artery perforation and coronary air embolism: Two fatal outcomes in percutaneous left atrial appendage occlusion. International Journal of Legal Medicine, 131(1), 191-197. doi: 10.1007/s00414-016-1486-1

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