Dr Andrew Clarkson
Position | Senior Lecturer |
---|---|
Department | Department of Anatomy |
Qualifications | BSc PGDipSc PhD |
Research summary | Stroke and neural regeneration |
Research
Research in Dr Clarkson's lab focuses on post-stroke neuroprotection and regeneration and repair mechanisms. My research is directed at promoting recovery of function following a stroke. The approaches used involve novel combinations of intensive rehabilitation, drug therapy and more recently stem cells to enhance brain repair processes. This utilises behavioural, electrophysiological, optical imaging and anatomical measures to assess recovery after stroke.
Publications
Potemkin, N., & Clarkson, A. N. (2023). Non-coding RNAs in stroke pathology, diagnostics, and therapeutics. Neurochemistry International, 162, 105467. doi: 10.1016/j.neuint.2022.105467
Qasim, M., Clarkson, A. N., & Hinkley, S. F. R. (2023). Green synthesis of carbon nanoparticles (CNPs) from biomass for biomedical applications. International Journal of Molecular Sciences, 24, 1023. doi: 10.3390/ijms24021023
Griem-Krey, N., Clarkson, A. N., & Wellendorph, P. (2022). CaMKIIα as a promising drug target for ischemic grey matter [Review]. Brain Sciences, 12(12), 1639. doi: 10.3390/brainsci12121639
Morris, G. P., Gowing, E. K., Courtney, J.-M., Coombe, H. E., King, N. E., Rewell, S. S. J., … Clarkson, A. N., & Sutherland, B. A. (2022). Vascular perfusion differs in two distinct PDGFRβ-positive zones within the ischemic core of male mice 2 weeks following photothrombotic stroke. Journal of Neuroscience Research. Advance online publication. doi: 10.1002/jnr.25146
Griem-Krey, N., Gauger, S. J., Gowing, E. K., Thiesen, L., Frølund, B., Clarkson, A. N., & Wellendorph, P. (2022). The CaMKIIα hub ligand Ph-HTBA promotes neuroprotection after focal ischemic stroke by a distinct molecular interaction. Biomedicine & Pharmacotherapy, 156, 113895. doi: 10.1016/j.biopha.2022.113895
Barzegar-Fallah, A., Houlton, J., Barwick, D., Shavandi, A., Ali, M. A., Clarkson, A. N., & Alimoradi, H. (2021). From barriers to bridges: Glycans in naonparenteral nanomedicines. In P. Kesharwani, S. Taurin & K. Greish (Eds.), Theory and applications of nonparenteral nanomedicines. (pp. 467-487). London, UK: Elsevier. doi: 10.1016/B978-0-12-820466-5.00019-3
Chapter in Book - Research
Lie, M. E. K., Al-Khawaja, A., Damgaard, M., Haugaard, A. S., Schousboe, A., Clarkson, A. N., & Wellendorph, P. (2017). Glial GABA transporters as modulators of inhibitory signalling in epilepsy and stroke. In A. Ortega & A. Schousboe (Eds.), Glial amino acid transporters. (pp. 137-167). Cham, Switzerland: Springer. doi: 10.1007/978-3-319-55769-4_7
Chapter in Book - Research
Clarkson, A. N., & Chebib, M. (2014). The role of peri-synaptic GABA receptors after stroke. In A. C. Errington, V. Crunelli & G. Di Giovanni (Eds.), Extrasynaptic GABAA receptors: The receptors (Vol. 27). (pp. 179-205). New York: Springer. doi: 10.1007/978-1-4939-1426-5_9
Chapter in Book - Research
Clarkson, A. N. (2009). Secondary cardiovascular abnormalities subsequent to cerebral hypoxia-ischaemia. In E. H. Bennington (Ed.), Horizons in world cardiovascular research (Vol. 1). New York: Nova Science.
Chapter in Book - Research
Clarkson, A. N. (2008). Secondary cardiovascular abnormalities subsequent to cerebral hypoxia-ischaemia. In O. M. Roux (Ed.), Brain hypoxia-ischemia research progress. (pp. 19-56). New York: Nova Science.
Chapter in Book - Research
Clarkson, A. N., & Appleton, I. (2007). Cerebral hypoxia-ischemia-induced neuronal and cardiac impairment. In C. Kaur (Ed.), Hypoxia and the central nervous system. (pp. 109-144). Trivandrum, India: Transworld Research Network.
Chapter in Book - Research
Griem-Krey, N., Clarkson, A. N., & Wellendorph, P. (2022). CaMKIIα as a promising drug target for ischemic grey matter [Review]. Brain Sciences, 12(12), 1639. doi: 10.3390/brainsci12121639
Journal - Research Article
Griem-Krey, N., Gauger, S. J., Gowing, E. K., Thiesen, L., Frølund, B., Clarkson, A. N., & Wellendorph, P. (2022). The CaMKIIα hub ligand Ph-HTBA promotes neuroprotection after focal ischemic stroke by a distinct molecular interaction. Biomedicine & Pharmacotherapy, 156, 113895. doi: 10.1016/j.biopha.2022.113895
Journal - Research Article
Houlton, J., Zubkova, O., & Clarkson, A. N. (2022). Recovery of post-stroke spatial memory and thalamocortical connectivity following novel glycomimetic and rhBDNF treatment. International Journal of Molecular Sciences, 23, 4817. doi: 10.3390/ijms23094817
Journal - Research Article
McLaughlin, A. W., McDowell, A., Clarkson, A. N., & Walker, G. F. (2022). Characterization of poly(lactic-co-glycolic acid) nanofibers electrospun using a sustainable green chemistry with a low toxicity solvent system. International Journal of Polymeric Materials & Polymeric Biomaterials, 71(13), 983-992. doi: 10.1080/00914037.2021.1933976
Journal - Research Article
Morris, G. P., Gowing, E. K., Courtney, J.-M., Coombe, H. E., King, N. E., Rewell, S. S. J., … Clarkson, A. N., & Sutherland, B. A. (2022). Vascular perfusion differs in two distinct PDGFRβ-positive zones within the ischemic core of male mice 2 weeks following photothrombotic stroke. Journal of Neuroscience Research. Advance online publication. doi: 10.1002/jnr.25146
Journal - Research Article
O'Sullivan, M. J., Oestreich, L. K. L., Wright, P., & Clarkson, A. N. (2022). Cholinergic and hippocampal systems facilitate cross-domain cognitive recovery after stroke. Brain. Advance online publication. doi: 10.1093/brain/awac070
Journal - Research Article
Smyth, L. C. D., Murray, H. C., Hill, M., van Leeuwen, E., Highet, B., Magon, N. J., … Mathiesen, S. N., Mockett, B., … Clarkson, A. N., … Abraham, W. C., Hughes, S. M., … Kettle, A. J., … Hampton, M. B. (2022). Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer's disease. Acta Neuropathologicca Communications, 10, 38. doi: 10.1186/s40478-022-01347-2
Journal - Research Article
Houlton, J., Barwick, D., & Clarkson, A. N. (2021). Frontal cortex stroke-induced impairment in spatial working memory on the trial-unique nonmatching-to-location task in mice. Neurobiology of Learning & Memory, 177, 107355. doi: 10.1016/j.nlm.2020.107355
Journal - Research Article
Jobson, D. D., Hase, Y., Clarkson, A. N., & Kalaria, R. N. (2021). The role of the medial prefrontal cortex in cognition, ageing and dementia. Brain Communications, 3(3), fcab125. doi: 10.1093/braincomms/fcab125
Journal - Research Article
Lamtahri, R., Hazime, M., Gowing, E. K., Nagaraja, R. Y., Maucotel, J., Alasoadura, M., … Clarkson, A. N., … Chuquet, J. (2021). The gliopeptide ODN, a ligand for the benzodiazepine site of GABAA receptors, boosts functional recovery after stroke. Journal of Neuroscience, 41(33), 7148-7159. doi: 10.1523/jneurosci.2255-20.2021
Journal - Research Article
Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbaka, S. M. Ø., Houlton, J., … Gowing, E. K., … Clarkson, A. N., & Wellendorph, P. (2021). GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain. PNAS, 118(31), e2108079118. doi: 10.1073/pnas.2108079118
Journal - Research Article
Neumann, S., Campbell, K., Woodall, M. J., Evans, M., Clarkson, A. N., & Young, S. L. (2021). Obesity has a systemic effect on immune cells in naïve and cancer-bearing mice. International Journal of Molecular Sciences, 22, 8803. doi: 10.3390/ijms22168803
Journal - Research Article
Shirazi, R. S., Vyssotski, M., Lagutin, K., Thompson, D., MacDonald, C., Luscombe, V., Glass, M., … Gowing, E. K., … Clarkson, A. N. (2021). Neuroprotective activity of new Δ3-N-acylethanolamines in a focal ischemia stroke model. Lipids. Advance online publication. doi: 10.1002/lipd.12326
Journal - Research Article
van Nieuwenhuijzen, P. S., Parker, K., Liao, V., Houlton, J., Kim, H.-Y., Johnston, G. A. R., … Clarkson, A. N. (2021). Targeting GABAC receptors improves post‐stroke motor recovery. Brain Sciences, 11(3), 315. doi: 10.3390/brainsci11030315
Journal - Research Article
Atienza-Roca, P., Kieser, D., Cui, X., Bathish, B., Ramaswamy, Y., Hooper, G. J., Clarkson, A. N., … Wise, L. M., Woodfield, T. B. F., & Lim, K. S. (2020). Visible light mediated PVA-tyramine hydrogels for covalent incorporation and tailorable release of functional growth factors. Biomaterials Science, 8(18), 5005-5019. doi: 10.1039/D0BM00603C
Journal - Research Article
Boni, R., Ali, A., Giteru, S. G., Shavandi, A., & Clarkson, A. N. (2020). Silk fibroin nanoscaffolds for neural tissue engineering. Journal of Materials Science: Materials in Medicine, 31, 81. doi: 10.1007/s10856-020-06422-5
Journal - Research Article
Cirillo, J., Mooney, R. A., Ackerley, S. J., Barber, P. A., Borges, V. M., Clarkson, A. N., … Byblow, W. D. (2020). Neurochemical balance and inhibition at the subacute stage after stroke. Journal of Neurophysiology, 123, 1775-1790. doi: 10.1152/jn.00561.2019
Journal - Research Article
McFall, A., Hietamies, T. M., Bernard, A., Aimable, M., Allan, S. M., Bath, P. M., … Clarkson, A. N., … Quinn, T. J. (2020). UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: Questionnaire and workshop proceedings. Journal of Cerebral Blood Flow & Metabolism, 47(7), 1402-1414. doi: 10.1177/0271678X20910552
Journal - Research Article
Soo, J. Y., Wiese, M. D., Dyson, R. M., Gray, C. L., Clarkson, A. N., Morrison, J. L., & Berry, M. J. (2020). Methamphetamine administration increases hepatic CYP1A2 but not CYP3A activity in female guinea pigs. PLoS ONE, 15(5), e0233010. doi: 10.1371/journal.pone.0233010
Journal - Research Article
Clarkson, A. N., Boothman-Burrell, L., Dósa, Z., Nagaraja, R. Y., Jin, L., Parker, K., … Neumann, S., Gowing, E. K., … Chebib, M. (2019). The flavonoid, 2'-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia. Journal of Cerebral Blood Flow & Metabolism, 39(7), 1266-1282. doi: 10.1177/0271678x18755628
Journal - Research Article
Hillman, K. L., Wall, H. J., Matthews, L. O., Gowing, E. K., & Clarkson, A. N. (2019). Altered hippocampal-prefrontal dynamics following medial prefrontal stroke in mouse. NeuroMolecular Medicine, 21, 401-413. doi: 10.1007/s12017-019-08557-3
Journal - Research Article
Houlton, J., Abumaria, N., Hinkley, S. F. R., & Clarkson, A. N. (2019). Therapeutic potential of neurotrophins for repair after brain injury: A helping hand from biomaterials. Frontiers in Neuroscience, 13, 790. doi: 10.3389/fnins.2019.00790
Journal - Research Article
Houlton, J., Zhou, L. Y. Y., Barwick, D., Gowing, E. K., & Clarkson, A. N. (2019). Stroke induces a BDNF-dependent improvement in cognitive flexibility in aged mice. Neural Plasticity, 2019, 1460890. doi: 10.1155/2019/1460890
Journal - Research Article
Lie, M. E. K., Gowing, E. K., Johansen, N. B., Dalby, N. O., Thiesen, L., Wellendorph, P., & Clarkson, A. N. (2019). GAT3 selective substrate L-isoserine upregulates GAT3 expression and increases functional recovery after a focal ischemic stroke in mice. Journal of Cerebral Blood Flow & Metabolism, 39(1), 74-88. doi: 10.1177/0271678x17744123
Journal - Research Article
Neumann, S., Boothman-Burrell, L., Gowing, E. K., Jacobsen, T. A., Ahring, P. K., Young, S. L., … Clarkson, A. N. (2019). The delta-subunit selective GABAA receptor modulator, DS2, improves stroke recovery via an anti-inflammatory mechanism. Frontiers in Neuroscience, 13, 1133. doi: 10.3389/fnins.2019.01133
Journal - Research Article
Allan, P. D., Tzeng, Y.-C., Gowing, E. K., Clarkson, A. N., & Fan, J.-L. (2018). Dietary nitrate supplementation reduces low frequency blood pressure fluctuations in rats following distal middle cerebral artery occlusion. Journal of Applied Physiology, 125(3), 862-869. doi: 10.1152/japplphysiol.01081.2017
Journal - Research Article
Evans, M. A., Ah Kim, H., Hann Ling, Y., Uong, S., Vinh, A., De Silva, T. M., … Clarkson, A. N., … Sobey, C. G. (2018). Vitamin D3 supplementation reduces subsequent brain injury and inflammation associated with ischemic stroke. NeuroMolecular Medicine, 20(1), 147-159. doi: 10.1007/s12017-018-8484-z
Journal - Research Article
Evans, M. A., Kim, H. A., De Silva, T. M., Arumugam, T. V., Clarkson, A. N., Drummond, G. R., … Sobey, C. G. (2018). Diet-induced vitamin D deficiency has no effect on acute post-stroke outcomes in young male mice. Journal of Cerebral Blood Flow & Metabolism, 38(11), 1968-1978. doi: 10.1177/0271678x17719208
Journal - Research Article
Evans, M. A., Lim, R., Kim, H. A., Chu, H. X., Gardiner-Mann, C. V., Taylor, K. W. E., … Neumann, S., … Gowing, E. K., … Clarkson, A. N., … Broughton, B. R. S. (2018). Acute or delayed systemic administration of human amnion epithelial cells improves outcomes in experimental stroke. Stroke, 49(3), 700-709. doi: 10.1161/strokeaha.117.019136
Journal - Research Article
Johnston, M., Clarkson, A. N., Gowing, E. K., Scarf, D., & Colombo, M. (2018). The effects of nidopallium caudolaterale inactivation on serial-order behaviour in pigeons (Columba livia). Journal of Neurophysiology, 120(3), 1143-1152. doi: 10.1152/jn.00167.2018
Journal - Research Article
Kluge, M. G., Jones, K., Ong, L. K., Gowing, E. K., Nilsson, M., Clarkson, A. N., & Walker, F. R. (2018). Age-dependent disturbances of neuronal and glial protein expression profiles in areas of secondary neurodegeneration post-stroke. Neuroscience, 393, 185-195. doi: 10.1016/j.neuroscience.2018.07.034
Journal - Research Article
Lie, M. E. K., Gowing, E. K., Clausen, R. P., Wellendorph, P., & Clarkson, A. N. (2018). Inhibition of GABA transporters fails to afford significant protection following focal cerebral ischemia. Journal of Cerebral Blood Flow & Metabolism, 38(1), 166-173. doi: 10.1177/0271678x17743669
Journal - Research Article
Parker, K., Berretta, A., Saenger, S., Sivaramakrishnan, M., Shirley, S. A., Metzger, F., & Clarkson, A. N. (2017). PEGylated insulin-like growth factor-I affords protection and facilitates recovery of lost functions post-focal ischemia. Scientific Reports, 7(1), 241. doi: 10.1038/s41598-017-00336-z
Journal - Research Article
Smith, G. P. S., McLaughlin, A., Clarkson, A. N., Gordon, K. C., & Walker, G. F. (2017). Raman microscopic imaging of electrospun fibers made from a polycaprolactone and polyethylene oxide blend. Vibrational Spectroscopy, 92, 27-34. doi: 10.1016/j.vibspec.2017.05.002
Journal - Research Article
Yarragudi, S. B., Richter, R., Lee, H., Walker, G. F., Clarkson, A. N., Kumar, H., & Rizwan, S. B. (2017). Formulation of olfactory-targeted microparticles with tamarind seed polysaccharide to improve nose-to-brain transport of drugs. Carbohydrate Polymers, 163, 216-226. doi: 10.1016/j.carbpol.2017.01.044
Journal - Research Article
Berretta, A., Gowing, E. K., Jasoni, C. L., & Clarkson, A. N. (2016). Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis. Scientific Reports, 6, 21896. doi: 10.1038/srep21896
Journal - Research Article
Che Has, A. T., Absalom, N., van Nieuwenhuijzen, P. S., Clarkson, A. N., Ahring, P. K., & Chebib, M. (2016). Zolpidem is a potent stoichiometry-selective modulator of α1β3 GABAA receptors: Evidence of a novel benzodiazepine site in the α1-α1 interface. Scientific Reports, 6, 28674. doi: 10.1038/srep28674
Journal - Research Article
Younus, M., Prentice, R. N., Clarkson, A. N., Boyd, B. J., & Rizwan, S. B. (2016). Incorporation of an endogenous neuromodulatory lipid, oleoylethanolamide, into cubosomes: Nanostructural characterization. Langmuir, 32(35), 8942-8950. doi: 10.1021/acs.langmuir.6b02395
Journal - Research Article
Zhou, L. Y. Y., Wright, T. E., & Clarkson, A. N. (2016). Prefrontal cortex stroke induces delayed impairment in spatial memory. Behavioural Brain Research, 296, 373-378. doi: 10.1016/j.bbr.2015.08.022
Journal - Research Article
Clarkson, A. N., Parker, K., Nilsson, M., Walker, F. R., & Gowing, E. K. (2015). Combined ampakine and BDNF treatments enhance poststroke functional recovery in aged mice via AKT-CREB signaling. Journal of Cerebral Blood Flow & Metabolism, 35, 1272-1279. doi: 10.1038/jcbfm.2015.33
Journal - Research Article
Jones, K. A., Zouikr, I., Patience, M., Clarkson, A. N., Isgaard, J., Johnson, S. J., … Walker, F. R. (2015). Chronic stress exacerbates neuronal loss associated with secondary neurodegeneration and suppresses microglial-like cells following focal motor cortex ischemia in the mouse. Brain, Behavior & Immunity, 48, 57-67. doi: 10.1016/j.bbi.2015.02.014
Journal - Research Article
Neumann, S., Shields, N. J., Balle, T., Chebib, M., & Clarkson, A. N. (2015). Innate immunity and inflammation post-stroke: An α7-nicotinic agonist perspective. International Journal of Molecular Sciences, 16(12), 29029-29046. doi: 10.3390/ijms161226141
Journal - Research Article
Patience, M. J., Zouikr, I., Jones, K., Clarkson, A. N., Isgaard, J., Johnson, S. J., … Nilsson, M. (2015). Photothrombotic stroke induces persistent ipsilateral and contralateral astrogliosis in key cognitive control nuclei. Neurochemical Research, 40(2), 362-371. doi: 10.1007/s11064-014-1487-8
Journal - Research Article
Van Slooten, A. R., Sun, Y., Clarkson, A. N., & Connor, B. J. (2015). L-NIO as a novel mechanism for inducing focal cerebral ischemia in the adult rat brain. Journal of Neuroscience Methods, 245, 44-57. doi: 10.1016/j.jneumeth.2015.02.022
Journal - Research Article
López-Valdés, H. E., Clarkson, A. N., Ao, Y., Charles, A. C., Carmichael, S. T., Sofroniew, M. V., & Brennan, K. C. (2014). Memantine enhances recovery from stroke. Stroke, 45, 2093-2100. doi: 10.1161/strokeaha.113.004476
Journal - Research Article
Bix, G. J., Gowing, E. K., & Clarkson, A. N. (2013). Perlecan domain V is neuroprotective and affords functional improvement in a photothrombotic stroke model in young and aged mice. Translational Stroke Research, 4, 515-523. doi: 10.1007/s12975-013-0266-1
Journal - Research Article
Clarkson, A. N., López-Valdés, H. E., Overman, J. J., Charles, A. C., Brennan, K. C., & Carmichael, S. T. (2013). Multimodal examination of structural and functional remapping in the mouse photothrombotic stroke model. Journal of Cerebral Blood Flow & Metabolism, 33, 716-723. doi: 10.1038/jcbfm.2013.7
Journal - Research Article
Imhoff, F. M., Yang, D., Mathew, S. F., Clarkson, A. N., Kawagishi, Y., Tate, W. P., Koishi, K., & McLennan, I. S. (2013). The type 2 anti-Müllerian hormone receptor has splice variants that are dominant-negative inhibitors. FEBS Letters, 587(12), 1749-1753. doi: 10.1016/j.febslet.2013.04.014
Journal - Research Article
Clarkson, A. N. (2012). Perisynaptic GABA receptors: The overzealous protector. Advances in Pharmacological Sciences, 2012, 708428. doi: 10.1155/2012/708428
Journal - Research Article
Overman, J. J., Clarkson, A. N., Wanner, I. B., Overman, W. T., Eckstein, I., Maguire, J. L., … Carmichael, S. T. (2012). A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke. PNAS, 109(33), E2230-E2239. doi: 10.1073/pnas.1204386109
Journal - Research Article
Clarkson, A. N., Overman, J. J., Zhong, S., Mueller, R., Lynch, G., & Carmichael, S. T. (2011). AMPA receptor-induced local brain-derived neurotrophic factor signaling mediates motor recovery after stroke. Journal of Neuroscience, 31(10), 3766-3775. doi: 10.1523/JNEUROSCI.5780-10.2011
Journal - Research Article
Clarkson, A. N., Talbot, C. L., Wang, P.-Y., MacLaughlin, D. T., Donahoe, P. K., & McLennan, I. S. (2011). Müllerian inhibiting substance is anterogradely transported and does not attenuate avulsion-induced death of hypoglossal motor neurons. Experimental Neurology, 231(2), 304-308. doi: 10.1016/j.expneurol.2010.12.019
Journal - Research Article
Nair, S. M., Rahman, R. M. A., Clarkson, A. N., Sutherland, B. A., Taurin, S., Sammut, I. A., & Appleton, I. (2011). Melatonin treatment following stroke induction modulates L-arginine metabolism. Journal of Pineal Research, 51(3), 313-323. doi: 10.1111/j.1600-079X.2011.00891.x
Journal - Research Article
Sutherland, B. A., Shaw, O. M., Clarkson, A. N., Winburn, I. C., Errington, A. C., Dixon, C. L., Lees, G., Sammut, I. A., & Appleton, I. (2011). Tin protoporphyrin provides protection following cerebral hypoxia-ischemia: Involvement of alternative pathways. Journal of Neuroscience Research, 89(8), 1284-1294. doi: 10.1002/jnr.22661
Journal - Research Article
Clarkson, A. N., Huang, B. S., MacIsaac, S. E., Mody, I., & Carmichael, S. T. (2010). Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke. Nature, 468(7321), 305-309. doi: 10.1038/nature09511
Journal - Research Article
Sutherland, B. A., Rahman, R. M. A., Clarkson, A. N., Shaw, O. M., Nair, S. M., & Appleton, I. (2009). Cerebral heme oxygenase 1 and 2 spatial distribution is modulated following injury from hypoxia-ischemia and middle cerebral artery occlusion in rats. Neuroscience Research, 65(4), 326-334. doi: 10.1016/j.neures.2009.08.007
Journal - Research Article
Wang, P.-Y., Protheroe, A., Clarkson, A. N., Imhoff, F., Koishi, K., & McLennan, I. S. (2009). Müllerian inhibiting substance contributes to sex-linked biases in the brain and behavior. PNAS, 106(17), 7203-7208. doi: 10.1073/pnas.0902253106
Journal - Research Article
Pugazhenthi, K., Kapoor, M., Clarkson, A. N., Hall, I., & Appleton, I. (2008). Melatonin accelerates the process of wound repair in full-thickness incisional wounds. Journal of Pineal Research, 44(4), 387-396. doi: 10.1111/j.1600-079X.2007.00541.x
Journal - Research Article
Vranyac-Tramoundanas, A., Harrison, J. C., Clarkson, A. N., Kapoor, M., Winburn, I. C., Kerr, D. S., & Sammut, I. A. (2008). Domoic acid impairment of cardiac energetics. Toxicological Sciences, 105(2), 395-407. doi: 10.1093/toxsci/kfn132
Journal - Research Article
Clarkson, A. N., Clarkson, J., Jackson, D. M., & Sammut, I. A. (2007). Mitochondrial involvement in transhemispheric diaschisis following hypoxia-ischemia: Clomethiazole-mediated amelioration. Neuroscience, 144, 547-561.
Journal - Research Article
Clarkson, A. N., Liu, H., Schiborra, F., Shaw, O., Sammut, I. A., Jackson, D. M., & Appleton, I. (2007). Angiogenesis as a predictive marker of neurological outcome following hypoxia-ischemia. Brain Research, 1171, 111-121.
Journal - Research Article
Hesp, B. R., Clarkson, A. N., Sawant, P. M., & Kerr, D. S. (2007). Domoic acid preconditioning and seizure induction in young and aged rats. Epilepsy Research, 76, 103-112.
Journal - Research Article
Ashton, J. C., Khalessi, A., Kapoor, M., Clarkson, A., Sammut, I. A., Darlington, C. L., & Smith, P. F. (2005). Characterization of mitochondrial respiratory chain energetics in the vestibular nucleus complex [Short Communication]. Acta Oto-Laryngologica, 125, 422-425.
Journal - Research Article
Clarkson, A. N., Liu, H., Rahman, R., Jackson, D. M., Appleton, I., & Kerr, D. S. (2005). Clomethiazole: Mechanisms underlying lasting neuroprotection after hypoxia-ischemia. FASEB Journal, 19(8), 1036-1038.
Journal - Research Article
Clarkson, A. N., Sutherland, B. A., & Appleton, I. (2005). The biology and pathology of hypoxia-ischemia: An update. Archivum Immunologiae et Therapiae Experimentalis, 53, 213-225.
Journal - Research Article
Sutherland, B. A., Shaw, O. M., Clarkson, A. N., Jackson, D. M., Sammut, I. A., & Appleton, I. (2005). Neuroprotective effects of (-)-epigallocatechin gallate following hypoxia-ischemia-induced brain damage: Novel mechanisms of action. FASEB Journal, 19(2), 258-260. doi: 10.1096/fj.04-2806fje
Journal - Research Article
Clarkson, A. N., Liu, H., Pearson, L., Kapoor, M., Harrison, J. C., Sammut, I. A., Jackson, D. M., & Appleton, I. (2004). Neuroprotective effects of spermine following hypoxia-ischemia-induced brain damage: A mechanistic study. FASEB Journal, 18(10), 1114-1116.
Journal - Research Article
Clarkson, A. N., Rahman, R. M. A., & Appleton, I. (2004). Inflammation and autoimmunity as a central theme in neurodegenerative disorders: Fact or fiction? Current Opinion in Investigational Drugs, 5(7), 706-713.
Journal - Research Article
Potemkin, N., & Clarkson, A. N. (2023). Non-coding RNAs in stroke pathology, diagnostics, and therapeutics. Neurochemistry International, 162, 105467. doi: 10.1016/j.neuint.2022.105467
Journal - Research Other
Qasim, M., Clarkson, A. N., & Hinkley, S. F. R. (2023). Green synthesis of carbon nanoparticles (CNPs) from biomass for biomedical applications. International Journal of Molecular Sciences, 24, 1023. doi: 10.3390/ijms24021023
Journal - Research Other
Boltze, J., Abe, K., Clarkson, A. N., Detante, O., Pimentel-Coelho, P. M., Rosado-de-Castro, P. H., & Janowski, M. (2020). Cell-based therapies for stroke: Promising solution or dead end? Frontiers in Neurology, 11, 171. doi: 10.3389/fneur.2020.00171
Journal - Research Other
Lumsden, S. C., Clarkson, A. N., & Cakmak, Y. O. (2020). Neuromodulation of the pineal gland via electrical stimulation of its sympathetic innervation pathway. Frontiers in Neuroscience, 14, 264. doi: 10.3389/fnins.2020.00264
Journal - Research Other
Abumaria, N., Li, W., & Clarkson, A. N. (2019). Role of the chanzyme TRPM7 in the nervous system in health and disease. Cellular & Molecular Life Sciences, 76, 3301-3310. doi: 10.1007/s00018-019-03124-2
Journal - Research Other
Bernhardt, J., Borschmann, K. N., Kwakkel, G., Burridge, J. H., Walker, M. F., Bird, M.-L., … Clarkson, A. N., … for the SRRR2 Collaboration. (2019). Setting the scene for the Second Stroke Recovery and Rehabilitation Roundtable. International Journal of Stroke, 14(5), 450-456. doi: 10.1177/1747493019851287
Journal - Research Other
McDonald, M. W., Black, S. E., Copland, D. A., Corbett, D., Dijkhuizen, R. M., Farr, T. D., … Clarkson, A. N., & O'Sullivan, M. J. (2019). Cognition in stroke rehabilitation and recovery research: Consensus-based core recommendations from the second Stroke Recovery and Rehabilitation Roundtable. International Journal of Stroke, 14(8), 774-782. doi: 10.1177/1747493019873600
Journal - Research Other
McDonald, M. W., Black, S. E., Copland, D. A., Corbett, D., Dijkhuizen, R. M., Farr, T. D., … Clarkson, A. N., & O'Sullivan, M. J. (2019). Cognition in stroke rehabilitation and recovery research: Consensus-based core recommendations from the second Stroke Recovery and Rehabilitation Roundtable. Neurorehabilitation & Neural Repair, 33(11), 943-950. doi: 10.1177/1545968319886444
Journal - Research Other
Boni, R., Ali, A., Shavandi, A., & Clarkson, A. N. (2018). Current and novel polymeric biomaterials for neural tissue engineering. Journal of Biomedical Science, 25, 90. doi: 10.1186/s12929-018-0491-8
Journal - Research Other
Berretta, A., Tzeng, Y.-C., & Clarkson, A. N. (2014). Post-stroke recovery: The role of activity-dependent release of brain-derived neurotrophic factor. Expert Review of Neurotherapeutics, 14(11), 1335-1344. doi: 10.1586/14737175.2014.969242
Journal - Research Other
Clarkson, A. N., & Carmichael, S. T. (2009). Cortical excitability and post-stroke recovery. Biochemical Society Transactions, 37(6), 1412-1414. doi: 10.1042/BST0371412
Journal - Research Other
Clarkson, A. N. (2007). Anesthetic-mediated protection/preconditioning during cerebral ischemia. Life Sciences, 80, 1157-1175.
Journal - Research Other
Kapoor, M., Clarkson, A., Sutherland, B. A., & Appleton, I. (2005). The role of antioxidants in models of inflammation: Emphasis on L-arginine and arachidonic acid metabolism. Inflammopharmacology, 12(5-6), 505-520.
Journal - Research Other