Associate Professor Cakmak is an associate professor in the Department of Anatomy. His research focuses on the neuromodulation of internal organs and the brain structures to modulate their functions and blood flow. Associate Professor Cakmak investigates the effects of different frequencies of non-invasive electrostimulation on internal organs blood flow to increase and decrease the blood flow. He also focus on investigating novel non-invasive stimulation techniques to normalize the neuronal network functions and alleviate the symptoms of neurological diseases.
Ongoing research:
- Non-invasive external electrostimulator for Parkinson’s Disease (Clinical Trial)
- Non-invasive vestibular nerve stimulation and structural plasticity in cerebrum and cerebellum and its effects on cognitive abilities (collaboration with Harvard University and Singapore University Imagery Lab)
- Modulation of the blood flow in cerebral arteries
Find out more about Dr Cakmak’s research
Publications
Cakmak, Y. O., Ozsoy, B., Ertan, S., Cakmak, O. O., Kiziltan, G., Yapici-Eser, H., … Gursoy-Ozdemir, Y. (2020). Intrinsic auricular muscle zone stimulation improves walking parameters of parkinson's patients faster than levodopa in the motion capture analysis: A pilot study. Frontiers in Neurology, 11, 546123. doi: 10.3389/fneur.2020.546123
Lumsden, S. C., Clarkson, A. N., & Cakmak, Y. O. (2020). Neuromodulation of the pineal gland via electrical stimulation of its sympathetic innervation pathway. Frontiers in Neuroscience, 14, 264. doi: 10.3389/fnins.2020.00264
Sukasem, A., Cakmak, Y. O., Khwaounjoo, P., Gharibans, A., & Du, P. (2020). The effects of low-and high-frequency non-invasive transcutaneous auricular vagal nerve stimulation (taVNS) on gastric slow waves evaluated using in vivo high-resolution mapping in porcine. Neurogastroenterology & Motility, 32, e13852. doi: 10.1111/nmo.13852
Gowen, C. L., Khwaounjoo, P., & Cakmak, Y. O. (2020). EMG-free monitorization of the acoustic startle reflex with a mobile phone: Implications of sound parameters with posture related responses. Sensors, 20, 5996. doi: 10.3390/s20215996
Cakmak, Y. O. (2019). Concerning auricular vagal nerve stimulation: Occult neural networks. Frontiers in Human Neuroscience, 13, 421. doi: 10.3389/fnhum.2019.00421
Journal - Research Article
Wang, C., Daniel, B. K., Asil, M., Khwaounjoo, P., & Cakmak, Y. O. (2020). A randomised control trial and comparative analysis of multi-dimensional learning tools in anatomy. Scientific Reports, 10, 6120. doi: 10.1038/s41598-020-62855-6
Gowen, C. L., Khwaounjoo, P., & Cakmak, Y. O. (2020). EMG-free monitorization of the acoustic startle reflex with a mobile phone: Implications of sound parameters with posture related responses. Sensors, 20, 5996. doi: 10.3390/s20215996
Sukasem, A., Cakmak, Y. O., Khwaounjoo, P., Gharibans, A., & Du, P. (2020). The effects of low-and high-frequency non-invasive transcutaneous auricular vagal nerve stimulation (taVNS) on gastric slow waves evaluated using in vivo high-resolution mapping in porcine. Neurogastroenterology & Motility, 32, e13852. doi: 10.1111/nmo.13852
Cakmak, Y. O., Ozsoy, B., Ertan, S., Cakmak, O. O., Kiziltan, G., Yapici-Eser, H., … Gursoy-Ozdemir, Y. (2020). Intrinsic auricular muscle zone stimulation improves walking parameters of parkinson's patients faster than levodopa in the motion capture analysis: A pilot study. Frontiers in Neurology, 11, 546123. doi: 10.3389/fneur.2020.546123
Berkay, D., Eser, H. Y., Sack, A. T., Çakmak, Y. Ö., & Balci, F. (2018). The modulatory role of pre-SMA in speed-accuracy tradeoff: A bi-directional TMS study. Neuropsychologia, 109, 255-261. doi: 10.1016/j.neuropsychologia.2017.12.031
Maharjan, A., Wang, E., Peng, M., & Cakmak, Y. O. (2018). Improvement of olfactory function with high frequency non-invasive auricular electrostimulation in healthy humans. Frontiers in Neuroscience, 12, 225. doi: 10.3389/fnins.2018.00225
Maharjan, A., Peng, M., & Cakmak, Y. O. (2018). Non-invasive high frequency median nerve stimulation effectively suppresses olfactory intensity perception in healthy males. Frontiers in Human Neuroscience, 12, 533. doi: 10.3389/fnhum.2018.00533
Cakmak, Y. O., Cotofana, S., Jäger, C., Morawski, M., Sora, M.-C., Werner, M., & Hammer, N. (2018). Peri-arterial autonomic innervation of the human ear. Scientific Reports, 8, 11469. doi: 10.1038/s41598-018-29839-z
Goktas, S., Yalcin, O., Ermek, E., Piskin, S., Capraz, C. T., Cakmak, Y. O., & Pekkan, K. (2017). Haemodynamic recovery properties of the torsioned testicular artery lumen. Scientific Reports, 7, 15570. doi: 10.1038/s41598-017-15680-3
Cakmak, Y. O., Ekinci, G., Heinecke, A., & Çavdar, S. (2017). A possible role of prolonged whirling episodes on structural plasticity of the cortical networks and altered vertigo perception: The cortex of Sufi Whirling Dervishes. Frontiers in Human Neuroscience, 11, 3. doi: 10.3389/fnhum.2017.00003
Tosun, T., Berkay, D., Sack, A. T., Çakmak, Y. Ö., & Balci, F. (2017). Inhibition of pre-Supplementary Motor Area by continuous theta burst stimulation leads to more cautious decision-making and more efficient sensory evidence integration. Journal of Cognitive Neuroscience, 29(8), 1433-1444. doi: 10.1162/jocn_a_01134
Cakmak, Y. O., Akpinar, I. N., & Yoldemir, T. (2017). Decreasing the uterine blood flow with electroacupuncture: Bidermatomal and monodermatomal applications. Gynecologic & Obstetric Investigation, 82(2), 151-156. doi: 10.1159/000446947
Cakmak, Y. O., Apaydin, H., Kiziltan, G., Gündüz, A., Ozsoy, B., Olcer, S., … Ertan, S. (2017). Rapid alleviation of Parkinson’s disease symptoms via electrostimulation of intrinsic auricular muscle zones. Frontiers in Human Neuroscience, 11, 338. doi: 10.3389/fnhum.2017.00338
Ozdogmus, O., Saban, E., Ozkan, M., Yildiz, S. D., Verimli, U., Cakmak, O., … Sehirli, U. (2016). Morphometric characteristics of caudal cranial nerves at petroclival region in fetuses. Anatomical Science International, 91, 246-249. doi: 10.1007/s12565-015-0291-0
Uslu, B., Cakmak, Y. O., Sehirli, Ü., Keskinoz, E. N., Cosgun, E., Arbak, S., & Yalin, A. (2016). Early onset of atherosclerosis of the carotid bifurcation in newborn cadavers. Journal of Clinical & Diagnostic Research, 10(5), AC01-AC05. doi: 10.7860/JCDR/2016/19827.7706
Acar, O., Esen, T., Colakoglu, B., Camli, M. F., & Cakmak, Y. O. (2015). Improving testicular blood flow with electroacupuncture-like percutaneous nerve stimulation in an experimental rat model of testicular torsion. Neuromodulation, 18(4), 324-328. doi: 10.1111/ner.12246
Cakmak, Y. O., Ergelen, R., Ekinci, G., & Kaspar, E. C. (2014). The short appendix vermiformis as a risk factor for colorectal cancer. Clinical Anatomy, 27(3), 498-502. doi: 10.1002/ca.22375
Cakmak, Y. O., Ozdogmus, Ö., Günay, Y., Gürbüzer, B., Tezulaş, E., Kaspar, E. C., & Hacioglu, H. (2014). An earplug technique to reduce the gag reflex during dental procedures. Forschende Komplementärmedizin [Research in Complementary Medicine], 21(2), 94-98. doi: 10.1159/000362140
Çavdar, S., Bay, H. H., Kirazll, Ö., Çakmak, Y. Ö., & Onat, F. (2013). Comparing GABAergic cell populations in the thalamic reticular nucleus of normal and genetic absence epilepsy rats from Strasbourg (GAERS). Neurological Sciences, 34(11), 1991-2000. doi: 10.1007/s10072-013-1435-4
Cakmak, Y. Ö., Cavdar, S., Yalın, A., Yener, N., & Ozdogmus, O. (2010). Myocadial bridges of the coronary arteries in the human fetal heart. Anatomical Science International, 85(3), 140-144. doi: 10.1007/s12565-009-0069-3
Üzün, İ., Gürdal, E., Çakmak, Y. Ö., Ozdogmus, O., & Çavdar, S. (2009). A reminder of the anatomy of the recurrent artery of Heubner. Central European Neurosurgery, 70(1), 36-38. doi: 10.1055/s-0028-1119379
Cakmak, Y. O. (2009). A review of the potential effect of electroacupuncture and moxibustion on cell repair and survival: The role of heat shock proteins. Acupuncture in Medicine, 27(4), 183-186. doi: 10.1136/aim.2009.001420
Cakmak, Y. O., Akpinar, I. N., Ekinci, G., & Bekiroglu, N. (2008). Point- and frequency-specific response of the testicular artery to abdominal electroacupuncture in humans. Fertility & Sterility, 90(5), 1732-1738. doi: 10.1016/j.fertnstert.2007.08.013
Çavdar, S., Onat, F. Y., Çakmak, Y. Ö., Yananli, H. R., Gülçebi, M., & Aker, R. (2008). The pathways connecting the hippocampal formation, the thalamic reuniens nucleus and the thalamic reticular nucleus in the rat. Journal of Anatomy, 212(3), 249-256. doi: 10.1111/j.1469-7580.2008.00858.x
Ozdogmus, O., Çakmak, Ö., Yalin, A., Keklik, D., Üzün, Ý., & Çavdar, S. (2008). Changing diameters of cerebral vessels with age in human autopsy specimens: Possible relationships to atherosclerotic changes. Zentralblatt für Neurochirurgie, 69(3), 139-143. doi: 10.1055/s-2007-1004588
Gürdal, E., Çakmak, Y. Ö., Ozdogmus, Ö., Yalçinkaya, M., Üzün, İ., Gögüsgeren, M. A., & Çavdar, S. (2007). Morphometric measurements of the caudal cranial nerves in the petroclival region. Zentralblatt für Neurochirurgie, 68(2), 47-49. doi: 10.1055/s-2007-981463
Aker, R. G., Özyurt, H. B., Yananli, H. R., Çakmak, Y. Ö., Özkaynakçi, A. E., Sehirli, Ü., … Onat, F. Y. (2006). GABAA receptor mediated transmission in the thalamic reticular nucleus of rats with genetic absence epilepsy shows regional differences: Functional implications. Brain Research, 1111(1), 213-221. doi: 10.1016/j.brainres.2006.06.118
Cakmak, Y. O. (2006). Epilepsy, electroacupuncture and the nucleus of the solitary tract. Acupuncture in Medicine, 24(4), 164-168. doi: 10.1136/aim.24.4.164
Çavdar, S., Onat, F., Çakmak, Y. Ö., Saka, E., Yananli, H. R., & Aker, R. (2006). Connections of the zona incerta to the reticular nucleus of the thalamus in the rat. Journal of Anatomy, 209(2), 251-258. doi: 10.1111/j.1469-7580.2006.00600.x
Journal - Research Other
Lumsden, S. C., Clarkson, A. N., & Cakmak, Y. O. (2020). Neuromodulation of the pineal gland via electrical stimulation of its sympathetic innervation pathway. Frontiers in Neuroscience, 14, 264. doi: 10.3389/fnins.2020.00264
Cakmak, Y. O. (2019). Concerning auricular vagal nerve stimulation: Occult neural networks. Frontiers in Human Neuroscience, 13, 421. doi: 10.3389/fnhum.2019.00421
Liugan, M., Zhang, M., & Cakmak, Y. O. (2018). Neuroprosthetics for auricular muscles: Neural networks and clinical aspects. Frontiers in Neurology, 8, 752. doi: 10.3389/fneur.2017.00752
Cakmak, Y. O. (2017). Rotorua, hydrogen sulphide and Parkinson’s disease: A possible beneficial link? New Zealand Medical Journal, 130(1455), 123-125. Retrieved from https://www.nzma.org.nz/journal
Cakmak, Y. O. (2016). Coffee consumption, smoking, and Parkinson's disease? The beneficial role of hydrogen sulfide. Movement Disorders, 31(3), 429. doi: 10.1002/mds.26526
Cakmak, Y. (2015). Provotella-derived hydrogen sulfide, constipation, and neuroprotection in Parkinson's disease. Movement Disorders, 30(8), 1151. doi: 10.1002/mds.26258
Cakmak, Y. O. (2012). TNFα theory for the beneficial effects of acupuncture on infantile colic: Formula-fed infants and probiotic treatments. Acupuncture in Medicine, 30(1), 70. doi: 10.1136/acupmed-2011-010125
Çakmak, Y. Ö., Akpinar, I. N., Yoldemir, T., & Çavdar, S. (2011). Decreasing bleeding due to uterine fibroid with electroacupuncture [Case report]. Fertility & Sterility, 96(1), e13-e15. doi: 10.1016/j.fertnstert.2011.03.110
Cakmak, Y. O. (2011). Infantile colic: Exploring the potential role of maternal acupuncture. Acupuncture in Medicine, 29(4), 295-297. doi: 10.1136/acupmed.2011.010065
Ozdogmus, O., Çakmak, Y. Ö., Coskun, M., Verimli, U., Cavdar, S., & Uzun, I. (2010). The high 2D:4D finger length ratio effects on atherosclerotic plaque development [Short communication]. Atherosclerosis, 209(1), 195-196. doi: 10.1016/j.atherosclerosis.2009.08.023
Cakmak, Y. O. (2010). Electroacupuncture reduces uterine artery blood flow impedance [Letter]. Taiwanese Journal of Obstetrics & Gynecology, 49(3). doi: 10.1016/S1028-4559(10)60084-8
Cakmak, Y. O. (2009). How acupuncture may relieve infantile colic symptoms—melatonin, serotonin and circadian rhythmicity [Letter]. Acupuncture in Medicine, 27(3), 134. doi: 10.1136/aim.2009.001172
Conference Contribution - Published proceedings: Abstract
Benninger, B., & Cakmak, Y. (2020). Innovative handheld ultrasound-probe-system utilizes artificial intelligence for teaching face-to-face sonoanatomy with human cadaver for lab and distance learning via cloud. Journal of Anatomy, 236(Suppl. 1), P2-E9. doi: 10.1111/joa.13163
