Associate Professor Cakmak is an associate professor in the Department of Anatomy. His research focuses on the neuromodulation of internal organs and the brain structures to modulate their functions and blood flow. Associate Professor Cakmak investigates the effects of different frequencies of non-invasive electrostimulation on internal organs blood flow to increase and decrease the blood flow. He also focus on investigating novel non-invasive stimulation techniques to normalize the neuronal network functions and alleviate the symptoms of neurological diseases.
Ongoing research:
- Non-invasive external electrostimulator for Parkinson’s Disease (Clinical Trial)
- Non-invasive vestibular nerve stimulation and structural plasticity in cerebrum and cerebellum and its effects on cognitive abilities (collaboration with Harvard University and Singapore University Imagery Lab)
- Modulation of the blood flow in cerebral arteries
Find out more about Dr Cakmak’s research
Publications
Cakmak, Y. O., Ozsoy, B., Ertan, S., Cakmak, O. O., Kiziltan, G., Yapici-Eser, H., … Gursoy-Ozdemir, Y. (2020). Intrinsic auricular muscle zone stimulation improves walking parameters of parkinson's patients faster than levodopa in the motion capture analysis: A pilot study. Frontiers in Neurology, 11, 546123. doi: 10.3389/fneur.2020.546123
Lumsden, S. C., Clarkson, A. N., & Cakmak, Y. O. (2020). Neuromodulation of the pineal gland via electrical stimulation of its sympathetic innervation pathway. Frontiers in Neuroscience, 14, 264. doi: 10.3389/fnins.2020.00264
Sukasem, A., Cakmak, Y. O., Khwaounjoo, P., Gharibans, A., & Du, P. (2020). The effects of low-and high-frequency non-invasive transcutaneous auricular vagal nerve stimulation (taVNS) on gastric slow waves evaluated using in vivo high-resolution mapping in porcine. Neurogastroenterology & Motility, 32, e13852. doi: 10.1111/nmo.13852
Gowen, C. L., Khwaounjoo, P., & Cakmak, Y. O. (2020). EMG-free monitorization of the acoustic startle reflex with a mobile phone: Implications of sound parameters with posture related responses. Sensors, 20, 5996. doi: 10.3390/s20215996
Cakmak, Y. O. (2019). Concerning auricular vagal nerve stimulation: Occult neural networks. Frontiers in Human Neuroscience, 13, 421. doi: 10.3389/fnhum.2019.00421
Cakmak, Y. O., Ozsoy, B., Ertan, S., Cakmak, O. O., Kiziltan, G., Yapici-Eser, H., … Gursoy-Ozdemir, Y. (2020). Intrinsic auricular muscle zone stimulation improves walking parameters of parkinson's patients faster than levodopa in the motion capture analysis: A pilot study. Frontiers in Neurology, 11, 546123. doi: 10.3389/fneur.2020.546123
Journal - Research Article
Lumsden, S. C., Clarkson, A. N., & Cakmak, Y. O. (2020). Neuromodulation of the pineal gland via electrical stimulation of its sympathetic innervation pathway. Frontiers in Neuroscience, 14, 264. doi: 10.3389/fnins.2020.00264
Journal - Research Other
Sukasem, A., Cakmak, Y. O., Khwaounjoo, P., Gharibans, A., & Du, P. (2020). The effects of low-and high-frequency non-invasive transcutaneous auricular vagal nerve stimulation (taVNS) on gastric slow waves evaluated using in vivo high-resolution mapping in porcine. Neurogastroenterology & Motility, 32, e13852. doi: 10.1111/nmo.13852
Journal - Research Article
Gowen, C. L., Khwaounjoo, P., & Cakmak, Y. O. (2020). EMG-free monitorization of the acoustic startle reflex with a mobile phone: Implications of sound parameters with posture related responses. Sensors, 20, 5996. doi: 10.3390/s20215996
Journal - Research Article
Cakmak, Y. O. (2019). Concerning auricular vagal nerve stimulation: Occult neural networks. Frontiers in Human Neuroscience, 13, 421. doi: 10.3389/fnhum.2019.00421
Journal - Research Other
Wang, C., Daniel, B. K., Asil, M., Khwaounjoo, P., & Cakmak, Y. O. (2020). A randomised control trial and comparative analysis of multi-dimensional learning tools in anatomy. Scientific Reports, 10, 6120. doi: 10.1038/s41598-020-62855-6
Journal - Research Article
Benninger, B., & Cakmak, Y. (2020). Innovative handheld ultrasound-probe-system utilizes artificial intelligence for teaching face-to-face sonoanatomy with human cadaver for lab and distance learning via cloud. Journal of Anatomy, 236(Suppl. 1), P2-E9. doi: 10.1111/joa.13163
Conference Contribution - Published proceedings: Abstract
Cakmak, Y. O., Cotofana, S., Jäger, C., Morawski, M., Sora, M.-C., Werner, M., & Hammer, N. (2018). Peri-arterial autonomic innervation of the human ear. Scientific Reports, 8, 11469. doi: 10.1038/s41598-018-29839-z
Journal - Research Article
Maharjan, A., Wang, E., Peng, M., & Cakmak, Y. O. (2018). Improvement of olfactory function with high frequency non-invasive auricular electrostimulation in healthy humans. Frontiers in Neuroscience, 12, 225. doi: 10.3389/fnins.2018.00225
Journal - Research Article
Liugan, M., Zhang, M., & Cakmak, Y. O. (2018). Neuroprosthetics for auricular muscles: Neural networks and clinical aspects. Frontiers in Neurology, 8, 752. doi: 10.3389/fneur.2017.00752
Journal - Research Other
Cakmak, Y. O., Apaydin, H., Kiziltan, G., Gündüz, A., Ozsoy, B., Olcer, S., … Ertan, S. (2017). Rapid alleviation of Parkinson’s disease symptoms via electrostimulation of intrinsic auricular muscle zones. Frontiers in Human Neuroscience, 11, 338. doi: 10.3389/fnhum.2017.00338
Journal - Research Article
Goktas, S., Yalcin, O., Ermek, E., Piskin, S., Capraz, C. T., Cakmak, Y. O., & Pekkan, K. (2017). Haemodynamic recovery properties of the torsioned testicular artery lumen. Scientific Reports, 7, 15570. doi: 10.1038/s41598-017-15680-3
Journal - Research Article
Tosun, T., Berkay, D., Sack, A. T., Çakmak, Y. Ö., & Balci, F. (2017). Inhibition of pre-Supplementary Motor Area by continuous theta burst stimulation leads to more cautious decision-making and more efficient sensory evidence integration. Journal of Cognitive Neuroscience, 29(8), 1433-1444. doi: 10.1162/jocn_a_01134
Journal - Research Article
Berkay, D., Eser, H. Y., Sack, A. T., Çakmak, Y. Ö., & Balci, F. (2018). The modulatory role of pre-SMA in speed-accuracy tradeoff: A bi-directional TMS study. Neuropsychologia, 109, 255-261. doi: 10.1016/j.neuropsychologia.2017.12.031
Journal - Research Article
Cakmak, Y. O., Akpinar, I. N., & Yoldemir, T. (2017). Decreasing the uterine blood flow with electroacupuncture: Bidermatomal and monodermatomal applications. Gynecologic & Obstetric Investigation, 82(2), 151-156. doi: 10.1159/000446947
Journal - Research Article
Cakmak, Y. O. (2017). Rotorua, hydrogen sulphide and Parkinson’s disease: A possible beneficial link? New Zealand Medical Journal, 130(1455), 123-125. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Other
Acar, O., Esen, T., Colakoglu, B., Camli, M. F., & Cakmak, Y. O. (2015). Improving testicular blood flow with electroacupuncture-like percutaneous nerve stimulation in an experimental rat model of testicular torsion. Neuromodulation, 18(4), 324-328. doi: 10.1111/ner.12246
Journal - Research Article
Cakmak, Y. O., Akpinar, I. N., Ekinci, G., & Bekiroglu, N. (2008). Point- and frequency-specific response of the testicular artery to abdominal electroacupuncture in humans. Fertility & Sterility, 90(5), 1732-1738. doi: 10.1016/j.fertnstert.2007.08.013
Journal - Research Article
Çakmak, Y. Ö., Akpinar, I. N., Yoldemir, T., & Çavdar, S. (2011). Decreasing bleeding due to uterine fibroid with electroacupuncture [Case report]. Fertility & Sterility, 96(1), e13-e15. doi: 10.1016/j.fertnstert.2011.03.110
Journal - Research Other
Cakmak, Y. (2015). Provotella-derived hydrogen sulfide, constipation, and neuroprotection in Parkinson's disease. Movement Disorders, 30(8), 1151. doi: 10.1002/mds.26258
Journal - Research Other
Cakmak, Y. O. (2016). Coffee consumption, smoking, and Parkinson's disease? The beneficial role of hydrogen sulfide. Movement Disorders, 31(3), 429. doi: 10.1002/mds.26526
Journal - Research Other
Uslu, B., Cakmak, Y. O., Sehirli, Ü., Keskinoz, E. N., Cosgun, E., Arbak, S., & Yalin, A. (2016). Early onset of atherosclerosis of the carotid bifurcation in newborn cadavers. Journal of Clinical & Diagnostic Research, 10(5), AC01-AC05. doi: 10.7860/JCDR/2016/19827.7706
Journal - Research Article
Ozdogmus, O., Saban, E., Ozkan, M., Yildiz, S. D., Verimli, U., Cakmak, O., … Sehirli, U. (2016). Morphometric characteristics of caudal cranial nerves at petroclival region in fetuses. Anatomical Science International, 91, 246-249. doi: 10.1007/s12565-015-0291-0
Journal - Research Article
Cakmak, Y. O., Ozdogmus, Ö., Günay, Y., Gürbüzer, B., Tezulaş, E., Kaspar, E. C., & Hacioglu, H. (2014). An earplug technique to reduce the gag reflex during dental procedures. Forschende Komplementärmedizin [Research in Complementary Medicine], 21(2), 94-98. doi: 10.1159/000362140
Journal - Research Article
Cakmak, Y. O., Ergelen, R., Ekinci, G., & Kaspar, E. C. (2014). The short appendix vermiformis as a risk factor for colorectal cancer. Clinical Anatomy, 27(3), 498-502. doi: 10.1002/ca.22375
Journal - Research Article
Çavdar, S., Bay, H. H., Kirazll, Ö., Çakmak, Y. Ö., & Onat, F. (2013). Comparing GABAergic cell populations in the thalamic reticular nucleus of normal and genetic absence epilepsy rats from Strasbourg (GAERS). Neurological Sciences, 34(11), 1991-2000. doi: 10.1007/s10072-013-1435-4
Journal - Research Article
Cakmak, Y. O. (2012). TNFα theory for the beneficial effects of acupuncture on infantile colic: Formula-fed infants and probiotic treatments. Acupuncture in Medicine, 30(1), 70. doi: 10.1136/acupmed-2011-010125
Journal - Research Other
Cakmak, Y. O. (2011). Infantile colic: Exploring the potential role of maternal acupuncture. Acupuncture in Medicine, 29(4), 295-297. doi: 10.1136/acupmed.2011.010065
Journal - Research Other
Cakmak, Y. O. (2010). Electroacupuncture reduces uterine artery blood flow impedance [Letter]. Taiwanese Journal of Obstetrics & Gynecology, 49(3). doi: 10.1016/S1028-4559(10)60084-8
Journal - Research Other
Cakmak, Y. Ö., Cavdar, S., Yalın, A., Yener, N., & Ozdogmus, O. (2010). Myocadial bridges of the coronary arteries in the human fetal heart. Anatomical Science International, 85(3), 140-144. doi: 10.1007/s12565-009-0069-3
Journal - Research Article
Ozdogmus, O., Çakmak, Y. Ö., Coskun, M., Verimli, U., Cavdar, S., & Uzun, I. (2010). The high 2D:4D finger length ratio effects on atherosclerotic plaque development [Short communication]. Atherosclerosis, 209(1), 195-196. doi: 10.1016/j.atherosclerosis.2009.08.023
Journal - Research Other
Üzün, İ., Gürdal, E., Çakmak, Y. Ö., Ozdogmus, O., & Çavdar, S. (2009). A reminder of the anatomy of the recurrent artery of Heubner. Central European Neurosurgery, 70(1), 36-38. doi: 10.1055/s-0028-1119379
Journal - Research Article
Cakmak, Y. O. (2009). A review of the potential effect of electroacupuncture and moxibustion on cell repair and survival: The role of heat shock proteins. Acupuncture in Medicine, 27(4), 183-186. doi: 10.1136/aim.2009.001420
Journal - Research Article
Cakmak, Y. O. (2009). How acupuncture may relieve infantile colic symptoms—melatonin, serotonin and circadian rhythmicity [Letter]. Acupuncture in Medicine, 27(3), 134. doi: 10.1136/aim.2009.001172
Journal - Research Other
Ozdogmus, O., Çakmak, Ö., Yalin, A., Keklik, D., Üzün, Ý., & Çavdar, S. (2008). Changing diameters of cerebral vessels with age in human autopsy specimens: Possible relationships to atherosclerotic changes. Zentralblatt für Neurochirurgie, 69(3), 139-143. doi: 10.1055/s-2007-1004588
Journal - Research Article
Çavdar, S., Onat, F. Y., Çakmak, Y. Ö., Yananli, H. R., Gülçebi, M., & Aker, R. (2008). The pathways connecting the hippocampal formation, the thalamic reuniens nucleus and the thalamic reticular nucleus in the rat. Journal of Anatomy, 212(3), 249-256. doi: 10.1111/j.1469-7580.2008.00858.x
Journal - Research Article
Gürdal, E., Çakmak, Y. Ö., Ozdogmus, Ö., Yalçinkaya, M., Üzün, İ., Gögüsgeren, M. A., & Çavdar, S. (2007). Morphometric measurements of the caudal cranial nerves in the petroclival region. Zentralblatt für Neurochirurgie, 68(2), 47-49. doi: 10.1055/s-2007-981463
Journal - Research Article
Çavdar, S., Onat, F., Çakmak, Y. Ö., Saka, E., Yananli, H. R., & Aker, R. (2006). Connections of the zona incerta to the reticular nucleus of the thalamus in the rat. Journal of Anatomy, 209(2), 251-258. doi: 10.1111/j.1469-7580.2006.00600.x
Journal - Research Article
Cakmak, Y. O. (2006). Epilepsy, electroacupuncture and the nucleus of the solitary tract. Acupuncture in Medicine, 24(4), 164-168. doi: 10.1136/aim.24.4.164
Journal - Research Article
Aker, R. G., Özyurt, H. B., Yananli, H. R., Çakmak, Y. Ö., Özkaynakçi, A. E., Sehirli, Ü., … Onat, F. Y. (2006). GABAA receptor mediated transmission in the thalamic reticular nucleus of rats with genetic absence epilepsy shows regional differences: Functional implications. Brain Research, 1111(1), 213-221. doi: 10.1016/j.brainres.2006.06.118
Journal - Research Article
Maharjan, A., Peng, M., & Cakmak, Y. O. (2018). Non-invasive high frequency median nerve stimulation effectively suppresses olfactory intensity perception in healthy males. Frontiers in Human Neuroscience, 12, 533. doi: 10.3389/fnhum.2018.00533
Journal - Research Article
Cakmak, Y. O., Ekinci, G., Heinecke, A., & Çavdar, S. (2017). A possible role of prolonged whirling episodes on structural plasticity of the cortical networks and altered vertigo perception: The cortex of Sufi Whirling Dervishes. Frontiers in Human Neuroscience, 11, 3. doi: 10.3389/fnhum.2017.00003
Journal - Research Article
