Merriman, T. R., & Flynn, T. J. (2013). Molecular genetics of hyperuricaemia and gout. In eLS. Chichester: John Wiley & Sons. doi: 10.1002/9780470015902.a0025153

Chapter in Book - Research

Merriman, T. R., & McKinney, C. (2013). An update on the genetic causes of hyperuricemia and gout. In N. Dalbeth, F. Perez-Ruiz & N. Schlesinger (Eds.), Gout. (pp. 54-69). London, UK: Future Medicine. doi: 10.2217/ebo.12.256

Chapter in Book - Research

Brandon, R., Jiang, Y., Yeu, R. Q., Tweedie-Cullen, R., Smallman, K., Doherty, G., … Leask, M. P., Merriman, T. R., … Murphy, R. (2023). Stratified glucose-lowering response to vildagliptin and pioglitazone by obesity and hypertriglyceridemia in a randomized crossover trial. Frontiers in Endocrinology, 13, 1091421. doi: 10.3389/fendo.2022.1091421

Journal - Research Article

Krishnan, M., Phipps-Green, A., Russell, E. M., Major, T. J., Cadzow, M., Stamp, L. K., Dalbeth, N., … Merriman, T. R., … Weeks, D. E. (2023). Association of rs9939609 in FTO with BMI among Polynesian peoples living in Aotearoa New Zealand and other Pacific nations. Journal of Human Genetics. Advance online publication. doi: 10.1038/s10038-023-01141-5

Journal - Research Article

Mandal, A. K., Leask, M. P., Sumpter, N. A., Choi, H. K., Merriman, T. R., & Mount, D. B. (2023). Genetic and physiological effects of insulin-like growth factor-1 (IGF-1) on human urate homeostasis. Journal of the American Society of Nephrology. Advance online publication. doi: 10.1681/ASN.0000000000000054

Journal - Research Article

Baker, M. G., Gurney, J., Moreland, N. J., Bennett, J., Oliver, J., Williamson, D. A., Pierse, N., … Merriman, T. R., … Edwards, R., … Thomson, W. M., Zhang, J., & Lennon, D. (2022). Risk factors for acute rheumatic fever: A case-control study. Lancet Regional Health: Western Pacific. Advance online publication. doi: 10.1016/j.lanwpc.2022.100508

Journal - Research Article

Carlson, J. C., Krishnan, M., Rosenthal, S. L., Russell, E. M., Zhang, J. Z., Hawley, N. L., Moors, J., … Stamp, L. K., … Merriman, T. R., … Minster, R. L. (2022). A stop-gain variant in BTNL9 is associated with atherogenic lipid profiles. Human Genetics & Genomic Advances. Advance online publication. doi: 10.1016/j.xhgg.2022.100155

Journal - Research Article

Dalbeth, N., Mihov, B., Stewart, A., Gamble, G. D., Merriman, T. R., Mount, D., … Stamp, L. K., & Horne, A. (2022). Effects of elevated serum urate on cardiometabolic and kidney function markers in a randomised clinical trial of inosine supplementation. Scientific Reports, 12(1), 12887. doi: 10.1038/s41598-022-17257-1

Journal - Research Article

Elsaid, K., Merriman, T. R., Rossitto, L.-A., Liu-Bryan, R., Karsh, J., Phipps-Green, A., … Cadzow, M., … Terkeltaub, R. (2022). Amplification of inflammation by lubricin deficiency implicated in incident, erosive gout independent of hyperuricemia. Arthritis & Rheumatology. Advance online publication. doi: 10.1002/art.42413

Journal - Research Article

Gao, Q., Cheng, X., Merriman, T. R., Wang, C., Cui, L., Zhang, H., … Lu, J. (2022). Manifestations de la goutte chez 9754 patients d’un centre clinique chinois: étude observationnelle sur 10 ans. Revue du Rhumatisme, 89, 65-71. doi: 10.1016/j.rhum.2021.07.002

Journal - Research Article

Han, L., Li, R., Lu, J., Ren, W., Ning, C., Pang, J., … Merriman, T. R., & Li, C. (2022). Association of the quantity, duration, and type of alcohol consumption on the development of gouty tophi. Arthritis Care & Research. Advance online publication. doi: 10.1002/acr.24968

Journal - Research Article

He, Y., Xue, X., Terkeltaub, R., Dalbeth, N., Merriman, T. R., Mount, D. B., … Li, C. (2022). Association of acidic urine pH with impaired renal function in primary gout patients: A Chinese population-based cross-sectional study. Arthritis Research & Therapy, 24(1), 32. doi: 10.1186/s13075-022-02725-w

Journal - Research Article

Hitchman, L. M., Faatoese, A., Merriman, T. R., Miller, A. L., Liau, Y., Graham, O. E. E., Kee, P. S., Pearson, J. F., … Cameron, V. A., Kennedy, M. A., & Maggo, S. D. S. (2022). Allelic diversity of the pharmacogene CYP2D6 in New Zealand Māori and Pacific peoples. Frontiers in Genetics, 13, 1016416. doi: 10.3389/fgene.2022.1016416

Journal - Research Article

Lee, K., Vakili, S., Burden, H. J., Adams, S., Smith, G. C., Kulatea, B., Wright-McNaughton, M., Sword, D., … King, F., Wilcox, P., Merriman, T. R., Krebs, J. D., Hall, R. M., Murphy, R., Merry, T. L., & Shepherd, P. R. (2022). The minor allele of the CREBRF rs373863828 p.R457Q coding variant is associated with reduced levels of myostatin in males: Implications for body composition. Molecular Metabolism. Advance online publication. doi: 10.1016/j.molmet.2022.101464

Journal - Research Article

Lin, K., McCormick, N., Yokose, C., Joshi, A. D., Lu, N., Curhan, G. C., Merriman, T. R., … Choi, H. K. (2022). Interactions between genetic risk and diet influencing risk of incident female gout: discovery and replication analysis of four prospective cohorts. Arthritis & Rheumatology. Advance online publication. doi: 10.1002/art.42419

Journal - Research Article

Lupi, A. S., Sumpter, N. A., Leask, M. P., O'Sullivan, J., Fadason, T., de los Campos, G., Merriman, T. R., … Vazquez, A. I. (2022). Local genetic covariance between serum urate and kidney function estimated with Bayesian multitrait models. Genes Genomes Genetics, jkac158. Advance online publication. doi: 10.1093/g3journal/jkac158

Journal - Research Article

McCormick, N., Yokose, C., Joshi, A. D., Sheehy, S., Rosenberg, L., Warner, E. T., … Merriman, T. R., … Choi, H. K. (2022). Racial and sex disparities in gout prevalence among US adults. JAMA Network Open, 5(8), e2226804. doi: 10.1001/jamanetworkopen.2022.26804

Journal - Research Article

Russell, E. M., Carlson, J. C., Krishnan, M., Hawley, N. L., Sun, G., Cheng, H., … Major, T. J., … Merriman, T. R., … Minster, R. L. (2022). CREBRF missense variant rs373863828 has both direct and indirect effects on type 2 diabetes and fasting glucose in Polynesian peoples living in Samoa and Aotearoa New Zealand. BMJ Open Diabetes Research & Care, 10, e002275. doi: 10.1136/bmjdrc-2021-002275

Journal - Research Article

Smith Diaz, N., Stocker, S. L., Stamp, L. K., Dalbeth, N., Phipps-Green, A. J., Merriman, T. R., & Wright, D. F. B. (2022). An allopurinol adherence tool using plasma oxypurinol concentrations. British Journal of Clinical Pharmacology. Advance online publication. doi: 10.1111/bcp.15516

Journal - Research Article

Stewart, S., Phipps-Green, A., Gamble, G. D., Stamp, L. K., Taylor, W. J., Neogi, T., Merriman, T. R., & Dalbeth, N. (2022). Is repeat serum urate testing superior to a single test to predict incident gout over time? PLoS ONE, 17(2), e0263175. doi: 10.1371/journal.pone.0263175

Journal - Research Article

Sumpter, N. A., Takei, R., Cadzow, M., Topless, R. K. G., Phipps-Green, A. J., Murphy, R., … Major, T. J., Stamp, L. K., … Merriman, T. R. (2022). Association of gout polygenic risk score with age at disease onset and tophaceous disease in European and Polynesian men with gout. Arthritis & Rheumatology. Advance online publication. doi: 10.1002/art.42393

Journal - Research Article

Sun, M., Sun, W., Zhao, X., Li, Z., Dalbeth, N., Ji, A., … Merriman, T. R., & Li, C. (2022). A machine learning-assisted model for renal urate underexcretion with genetic and clinical variables among Chinese men with gout. Arthritis Research & Therapy, 24, 67. doi: 10.1186/s13075-022-02755-4

Journal - Research Article

Topless, R. K., Gaffo, A., Stamp, L. K., Robinson, P. C., Dalbeth, N., & Merriman, T. R. (2022). Gout and the risk of COVID-19 diagnosis and death in the UK Biobank: A population-based study. Lancet Rheumatology, 4, e274-e281. doi: 10.1016/S2665-9913(21)00401-X

Journal - Research Article

Topless, R., Green, R., Morgan, S. L., Robinson, P., Merriman, T., & Gaffo, A. L. (2022). Folic acid and methotrexate use and their association with COVID-19 diagnosis and mortality: A case-control analysis from the UK Biobank. BMJ Open, 12, e062945. doi: 10.1136/bmjopen-2022-062945

Journal - Research Article

Topless, R., Noorbaloochi, S., Merriman, T. R., & Singh, J. A. (2022). Change in serum urate level with urate-lowering therapy initiation associates in the immediate term with patient-reported outcomes in people with gout. Seminars in Arthritis & Rheumatism. Advance online publication. doi: 10.1016/j.semarthrit.2022.152057

Journal - Research Article

Wang, K., Cadzow, M., Bixley, M., Leask, M. P., Merriman, M. E., Yang, Q., … Takei, R., Phipps-Green, A., Major, T. J., Topless, R., … Stamp, L. K., … Merriman, T. R. (2022). A Polynesian-specific copy number variant encompassing the MHC Class I Polypeptide-related Sequence A (MICA) gene associates with gout. Human Molecular Genetics. Advance online publication. doi: 10.1093/hmg/ddac094

Journal - Research Article

Xue, X., Yuan, X., Han, L., Li, X., Merriman, T. R., Cui, L., … Li, C. (2022). Effect of clinical typing on serum urate targets of benzbromarone in Chinese gout patients: A prospective cohort study. Frontiers in Medicine, 8, 806710. doi: 10.3389/fmed.2021.806710

Journal - Research Article

Zhang, J. Z., Heinsberg, L. W., Krishnan, M., Hawley, N. L., Major, T. J., Carlson, J. C., … Stamp, L. K., … Merriman, T. R., & Weeks, D. E. (2022). Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries. Genetic Epidemiology. Advance online publication. doi: 10.1002/gepi.22508

Journal - Research Article

Al-Ani, A. H., Antoun, J. S., Thomson, W. M., Topless, R., Merriman, T. R., & Farella, M. (2021). Common variants of EDA are associated with non-syndromic hypodontia. Orthodontics & Craniofacial Research, 24, 155-163. doi: 10.1111/ocr.12419

Journal - Research Article

Badii, M., Gaal, O. I., Cleophas, M. C., Klück, V., Davar, R., Habibi, E., … Stamp, L. K., … Phipps-Green, A. J., … Merriman, T. R., … Joosten, L. A. B. (2021). Urate-induced epigenetic modifications in myeloid cells. Arthritis Research & Therapy, 23, 202. doi: 10.1186/s13075-021-02580-1

Journal - Research Article

Burden, H. J., Adams, S., Kulatea, B., Wright-McNaughton, M. E., Sword, D., Ormsbee, J. J., … Merriman, T. R., … Krebs, J. D., Hall, R. M., … Merry, T. L. (2021). The CREBRF diabetes-protective rs373863828-A allele is associated with enhanced early insulin release in men of Māori and Pacific ancestry. Diabetologia. Advance online publication. doi: 10.1007/s00125-021-05552-x

Journal - Research Article

Colantonio, L. D., Reynolds, R. J., Merriman, T. R., Gaffo, A., Singh, J. A., Plante, T. B., … Irvin, M. R. (2021). Higher serum urate levels are associated with an increased risk for sudden cardiac death. Journal of Rheumatology, 48, 1745-1753. doi: 10.3899/jrheum.210139

Journal - Research Article

Dalbeth, N., Horne, A., Mihov, B., Stewart, A., Gamble, G. D., Merriman, T. R., Stamp, L. K., & Reid, I. R. (2021). Elevated urate does not alter bone turnover markers: Randomized controlled trial of inosine supplementation in post-menopausal women. Arthritis & Rheumatology, 73(9), 1758-1764. doi: 10.1002/art.41691

Journal - Research Article

Emde, A.-K., Phipps-Green, A., Cadzow, M., Gallagher, C. S., Major, T. J., Merriman, M. E., Topless, R. K., Takei, R., Dalbeth, N., … Stamp, L. K., … Wilcox, P. L., … Merriman, T. R., & Castel, S. E. (2021). Mid-pass whole genome sequencing enables biomedical genetic studies of diverse populations. BMC Genomics, 22, 666. doi: 10.1186/s12864-021-07949-9

Journal - Research Article

Gao, Q., Cheng, X., Merriman, T. R., Wang, C., Cui, L., Zhang, H., … Lu, J. (2021). Trends in the manifestations of 9754 gout patients in a Chinese clinical center: A 10-year observational study. Joint Bone Spine, 88, 105078. doi: 10.1016/j.jbspin.2020.09.010

Journal - Research Article

Ji, A., Shaukat, A., Takei, R., Bixley, M., Cadzow, M., Topless, R. K., Major, T. J., Phipps-Green, A., Merriman, M. E., … Stamp, L. K., Dalbeth, N., … Merriman, T. R. (2021). Aotearoa New Zealand Māori and Pacific population-specific gout risk variants: CLNK is a separate risk gene at the SLC2A9 locus. Journal of Rheumatology, 48, 1736-1744. doi: 10.3899/jrheum.201684

Journal - Research Article

Leask, M. P., & Merriman, T. R. (2021). The genetic basis of urate control and gout: Insights into molecular pathogenesis from follow-up study of genome-wide association study loci. Best Practice & Research: Clinical Rheumatology, 101721. Advance online publication. doi: 10.1016/j.berh.2021.101721

Journal - Research Article

Li, X., Sun, W., Lu, J., He, Y., Chen, Y., Ren, W., … Merriman, T. R., & Li, C. (2021). Effects of fenofibrate therapy on renal function in primary gout patients. Rheumatology, 60, 5020-5027. doi: 10.1093/rheumatology/keab231

Journal - Research Article

Lin, W., Farella, M., Antoun, J. S., Topless, R. K., Merriman, T. R., & Michelotti, A. (2021). Factors associated with orthodontic pain. Journal of Oral Rehabilitation, 48, 1135-1143. doi: 10.1111/joor.13227

Journal - Research Article

Mandal, A. K., Leask, M. P., Estiverne, C., Choi, H. K., Merriman, T. R., & Mount, D. B. (2021). Genetic and physiological effects of insulin on human urate homeostasis. Frontiers in Physiology, 12, 713710. doi: 10.3389/fphys.2021.713710

Journal - Research Article

McCormick, N., O'Connor, M. J., Yokose, C., Merriman, T. R., Mount, D. B., Leong, A., & Choi, H. K. (2021). Assessing the causal relationships between insulin resistance and hyperuricemia and gout using bidirectional Mendelian randomization. Arthritis & Rheumatology, 73(11), 2096-2104. doi: 10.1002/art.41779

Journal - Research Article

Narang, R. K., Gamble, G. G., Topless, R., Cadzow, M., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2021). Assessing the relationship between serum urate and urolithiasis using Mendelian randomization: An analysis of the UK Biobank. American Journal of Kidney Diseases, 78(2), 210-218. doi: 10.1053/j.ajkd.2020.11.018

Journal - Research Article

Ran, Z., Xue, X., Han, L., Terkeltaub, R., Merriman, T. R., Zhao, T., … Li, C. (2021). Decrease in serum urate level is associated with loss of visceral fat in male gout patients. Frontiers in Endocrinology, 12, 724822. doi: 10.3389/fendo.2021.724822

Journal - Research Article

Reynolds, R. J., Irvin, M. R., Bridges, S. L., Kim, H., Merriman, T. R., Arnett, D. K., … Vazquez, A. I. (2021). Genetic correlations between traits associated with hyperuricemia, gout, and comorbidities. European Journal of Human Genetics, 29, 1438-1445. doi: 10.1038/s41431-021-00830-z

Journal - Research Article

Robinson, P. C., Frampton, C., Phipps-Green, A., Neogi, T., Stamp, L., Taylor, W., Merriman, T. R., & Dalbeth, N. (2021). Longitudinal development of incident gout from low-normal baseline serum urate concentrations: Individual participant data analysis. BMC Rheumatology, 5(1), 33. doi: 10.1186/s41927-021-00204-4

Journal - Research Article

Shen, X., Wang, C., Liang, N., Liu, Z., Li, X., Zhu, Z.-J., Merriman, T. R., Dalbeth, N., … Yin, H. (2021). Serum metabolomics identifies dysregulated pathways and potential metabolic biomarkers for hyperuricemia and gout. Arthritis & Rheumatology, 73(9), 1738-1748. doi: 10.1002/art.41733

Journal - Research Article

Takei, R., Cadzow, M., Markie, D., Bixley, M., Phipps-Green, A., Major, T. J., … Stamp, L. K., … Merriman, T. R., & Wei, W.-H. (2021). Trans-ancestral dissection of urate- and gout-associated major loci SLC2A9 and ABCG2 reveals primate-specific regulatory effects. Journal of Human Genetics, 66, 161-169. doi: 10.1038/s10038-020-0821-z

Journal - Research Article

Te Morenga, L., Kruimer, D., McLean, R., Sabadel, A. J. M., Van Hale, R., Tatin, X., … Mann, J., & Merriman, T. (2021). Associations between sugars intakes and urinary sugars excretion and carbon stable isotope ratios in red blood cells as biomarkers of sugars intake in a predominantly Māori population. Frontiers in Nutrition, 8, 637267. doi: 10.3389/fnut.2021.637267

Journal - Research Article

Topless, R. K. G., Major, T. J., Florez, J. C., Hirschhorn, J. N., Cadzow, M., Dalbeth, N., Stamp, L. K., Wilcox, P. L., … Merriman, T. R. (2021). The comparative effect of exposure to various risk factors on the risk of hyperuricaemia: Diet has a weak causal effect. Arthritis Research & Therapy, 23(1), 75. doi: 10.1186/s13075-021-02444-8

Journal - Research Article

Topless, R. K., Phipps-Green, A., Leask, M., Dalbeth, N., Stamp, L. K., Robinson, P. C., & Merriman, T. R. (2021). Gout, rheumatoid arthritis, and the risk of death related to coronavirus disease 2019: An analysis of the UK Biobank. ACR Open Rheumatology, 3(5), 333-340. doi: 10.1002/acr2.11252

Journal - Research Article

Wiggins, G. A. R., Black, M. A., Dunbier, A., Merriman, T. R., Pearson, J. F., & Walker, L. C. (2021). Variable expression quantitative trait loci analysis of breast cancer risk variants. Scientific Reports, 11(1), 7192. doi: 10.1038/s41598-021-86690-5

Journal - Research Article

Xue, X., Liu, Z., Li, X., Lu, J., Wang, C., Wang, X., … Merriman, T. R., … Cui, L. (2021). The efficacy and safety of citrate mixture vs sodium bicarbonate on urine alkalization in Chinese primary gout patients with benzbromarone: A prospective, randomized controlled study. Rheumatology, 60, 2661-2671. doi: 10.1093/rheumatology/keaa668

Journal - Research Article

Zhang, H., Li, H., Phipps Green, A., Wang, M., Yan, F., Li, M., … Merriman, T. R., & Li, C. (2021). Association of low-level environmental exposure to cadmium and lead with gout flare using a cohort study design. Chemosphere, 280, 130648. doi: 10.1016/j.chemosphere.2021.130648

Journal - Research Article

Bodofsky, S., Merriman, T. R., Thomas, T. J., & Schlesinger, N. (2020). Advances in our understanding of gout as an auto-inflammatory disease. Seminars in Arthritis & Rheumatism, 50, 1089-1100. doi: 10.1016/j.semarthrit.2020.06.015

Journal - Research Article

Boocock, J., Leask, M., Okada, Y., Asian Genetic Epidemiology Network (AGEN) Consortium, Matsuo, H., Shi, Y., … Cadzow, M., Gosling, A. L., Major, T. J., Horsfield, J. A., … Merriman, T. R. (2020). Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control. Human Molecular Genetics, 29(6), 923-943. doi: 10.1093/hmg/ddaa013

Journal - Research Article

Chen, H., Zhao, L., Liu, F., Chen, S., Hu, Z., Chen, L., … Merriman, T. R., & Min, J. Z. (2020). Urate in fingernail represents the deposition of urate burden in gout patients. Scientific Reports, 10, 15575. doi: 10.1038/s41598-020-72505-6

Journal - Research Article

Chung, P., Logge, W. B., Riordan, B. C., Haber, P. S., Merriman, M. E., Phipps-Green, A., Topless, R. K., Merriman, T. R., Conner, T., & Morley, K. C. (2020). Genetic polymorphisms on OPRM1, DRD2, DRD4, and COMT in young adults: Lack of association with alcohol consumption. Frontiers in Psychiatry, 11, 549429. doi: 10.3389/fpsyt.2020.549429

Journal - Research Article

Hoque, K. M., Dixon, E. E., Lewis, R. M., Allan, J., Gamble, G. D., Phipps-Green, A. J., … Stamp, L. K., Merriman, T. R., … Woodward, O. M. (2020). The ABCG2 Q141K hyperuricemia and gout associated variant illuminates the physiology of human urate excretion. Nature Communications, 11, 2767. doi: 10.1038/s41467-020-16525-w

Journal - Research Article

Klück, V., van Deuren, R. C., Cavalli, G., Shaukat, A., Arts, P., Cleophas, M. C., … Stamp, L. K., … Merriman, T. R., … Joosten, L. A. B. (2020). Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout. Annals of the Rheumatic Diseases, 79(4), 536-544. doi: 10.1136/annrheumdis-2019-216233

Journal - Research Article

Krishnan, M., Murphy, R., Okesene-Gafa, K. A. M., Ji, M., Thompson, J. M. D., Taylor, R. S., Merriman, T. R., … McKinlay, C. J. D. (2020). The Pacific-specific CREBRF rs373863828 allele protects against gestational diabetes mellitus in Māori and Pacific women with obesity. Diabetologia, 63(10), 2169-2176. doi: 10.1007/s00125-020-05202-8

Journal - Research Article

Leask, M. P., Sumpter, N. A., Lupi, A. S., Vazquez, A. I., Reynolds, R. J., Mount, D. B., & Merriman, T. R. (2020). The shared genetic basis of hyperuricemia, gout, and kidney function. Seminars in Nephrology, 40(6), 586-599. doi: 10.1016/j.semnephrol.2020.12.002

Journal - Research Article

Metcalfe, L. K., Krishnan, M., Turner, N., Yaghootkar, H., Merry, T. L., Dewes, O., … Stamp, L. K., Merriman, T. R., … Murphy, R. (2020). The Māori and Pacific specific CREBRF variant and adult height. International Journal of Obesity, 44, 748-752. doi: 10.1038/s41366-019-0437-6

Journal - Research Article

Morgan, B. M., Brown, A. N., Deo, N., Harrop, T. W. R., Taiaroa, G., Mace, P. D., Wilbanks, S. M., Merriman, T. R., Williams, M. J. A., & McCormick, S. P. A. (2020). Nonsynonymous SNPs in LPA homologous to plasminogen deficiency mutants represent novel null apo(a) alleles. Journal of Lipid Research, 61, 432-444. doi: 10.1194/jlr.M094540

Journal - Research Article

Nakayama, A., Nakatochi, M., Kawamura, Y., Yamamoto, K., Nakaoka, H., Shimizu, S., … Major, T. J., Merriman, T. R., … on behalf of Japan Gout Genomics Consortium (Japan Gout). (2020). Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients. Annals of the Rheumatic Diseases, 79, 657-665. doi: 10.1136/annrheumdis-2019-216644

Journal - Research Article

Narang, R. K., Gamble, G., Phipps-Green, A. J., Topless, R., Cadzow, M., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2020). Do serum urate-associated genetic variants influence gout risk in people on diuretics? Analysis of the UK Biobank. Journal of Rheumatology, 47, 1704-1711. doi: 10.3899/jrheum.191005

Journal - Research Article

Stamp, L. K., Chapman, P. T., Barclay, M., Horne, A., Frampton, C., Merriman, T. R., Wright, D. F. B., … Dalbeth, N. (2020). Relationships between allopurinol dose, oxypurinol concentration and urate-lowering response: In search of a minimum effective oxypurinol concentration. Clinical & Translational Science, 13, 110-115. doi: 10.1111/cts.12686

Journal - Research Article

Tai, V., Narang, R. K., Gamble, G., Cadzow, M., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2020). Do serum urate-associated genetic variants differentially contribute to gout risk according to body mass index? Analysis of the UK Biobank. Arthritis & Rheumatology, 72(7), 1184-1191. doi: 10.1002/art.41219

Journal - Research Article

Wang, Z., Zhao, Y., Phipps-Green, A., Liu-Bryan, R., Ceponis, A., Boyle, D. L., … Merriman, T. R., … Terkeltaub, R. (2020). Differential DNA methylation of networked signaling, transcriptional, innate and adaptive immunity, and osteoclastogenesis genes and pathways in gout. Arthritis & Rheumatology, 72(5), 802-814. doi: 10.1002/art.41173

Journal - Research Article

Winbo, A., Earle, N., Marcondes, L., Crawford, J., Prosser, D. O., Love, D. R., Merriman, T. R., Cadzow, M., … Skinner, J. R. (2020). Genetic testing in Polynesian long QT syndrome probands reveals a lower diagnostic yield and an increased prevalence of rare variants. Heart Rhythm, 17(8), 1304-1311. doi: 10.1016/j.hrthm.2020.03.015

Journal - Research Article

Wrigley, R., Phipps-Green, A. J., Topless, R. K., Major, T. J., Cadzow, M., Riches, P., … Stamp, L. K., … Merriman, T. R. (2020). Pleiotropic effect of the ABCG2 gene in gout: Involvement in serum urate levels and progression from hyperuricemia to gout. Arthritis Research & Therapy, 22, 45. doi: 10.1186/s13075-020-2136-z

Journal - Research Article

Zaidi, F., Narang, R. K., Phipps-Green, A., Gamble, G. G., Tausche, A.-K., So, A., … Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2020). Systematic genetic analysis of early-onset gout: ABCG2 is the only associated locus. Rheumatology, 59, 2544-2549. doi: 10.1093/rheumatology/kez685

Journal - Research Article

Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., … Bixley, M. J., … Merriman, T. R., … Wilson, J. F. (2019). Associations of autozygosity with a broad range of human phenotypes. Nature Communications, 10, 4957. doi: 10.1038/s41467-019-12283-6

Journal - Research Article

Jordan, D. M., Choi, H. K., Verbanck, M., Topless, R., Won, H.-H., Nadkarni, G., Merriman, T. R., & Do, R. (2019). No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study. PLoS Medicine, 16(1), e1002725. doi: 10.1371/journal.pmed.1002725

Journal - Research Article

Kawamura, Y., Nakaoka, H., Nakayama, A., Okada, Y., Yamamoto, K., Higashino, T., … Merriman, T. R., … Matsuo, H. (2019). Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout. Annals of the Rheumatic Diseases, 78, 1430-1437. doi: 10.1136/annrheumdis-2019-215521

Journal - Research Article

Leask, M., Dowdle, A., Salvesen, H., Topless, R., Fadason, T., Wei, W., … Marsman, J., Antony, J., … Merriman, T. R., & Horsfield, J. A. (2019). Functional urate-associated genetic variants influence expression of lincRNAs LINC01229 and MAFTRR. Frontiers in Genetics, 9, 733. doi: 10.3389/fgene.2018.00733

Journal - Research Article

Lu, J., Dalbeth, N., Yin, H., Li, C., Merriman, T. R., & Wei, W.-H. (2019). Mouse models for human hyperuricaemia: A critical review. Nature Reviews Rheumatology, 15, 413-426. doi: 10.1038/s41584-019-0222-x

Journal - Research Article

Lu, J., Sun, M., Wu, X., Yuan, X., Liu, Z., Qu, X., … Merriman, T. R., & Li, C. (2019). Urate-lowering therapy alleviates atherosclerosis inflammatory response factors and neointimal lesions in a mouse model of induced carotid atherosclerosis. FEBS Journal, 286, 1346-1359. doi: 10.1111/febs.14768

Journal - Research Article

Murphy, R., Gamble, G. D., House, M., Pool, B., Horne, A., Merriman, T. R., & Dalbeth, N. (2019). Greater insulin response to acute fructose ingestion among Māori and Pacific people compared to European people living in Aotearoa New Zealand. Internal Medicine Journal, 49, 196-202. doi: 10.1111/imj.14135

Journal - Research Article

Vazirpanah, N., Ottria, A., van der Linden, M., Wichers, C. G. K., Schuiveling, M., van Lochem, E., Phipps-Green, A., Merriman, T., … Broen, J. C. A. (2019). mTOR inhibition by metformin impacts monosodium urate crystal-induced inflammation and cell death in gout: A prelude to a new add-on therapy? Annals of the Rheumatic Diseases, 78, 663-671. doi: 10.1136/annrheumdis-2018-214656

Journal - Research Article

Conner, T. S., McFarlane, K. G., Choukri, M., Riordan, B. C., Flett, J. A. M., Phipps-Green, A. J., Topless, R. K., Merriman, M. E., & Merriman, T. R. (2018). The oxytocin receptor gene (OXTR) variant rs53576 is not related to emotional traits or states in young adults [Brief research report]. Frontiers in Psychology, 9, 2548. doi: 10.3389/fpsyg.2018.02548

Journal - Research Article

Fanning, N., Merriman, T. R., Dalbeth, N., & Stamp, L. K. (2018). An association of smoking with serum urate and gout: A health paradox. Seminars in Arthritis & Rheumatism, 47(6), 825-842. doi: 10.1016/j.semarthrit.2017.11.004

Journal - Research Article

Fatima, T., McKinney, C., Major, T. J., Stamp, L. K., Dalbeth, N., Iverson, C., Merriman, T. R., & Miner, J. N. (2018). The relationship between ferritin and urate levels and risk of gout. Arthritis Research & Therapy, 20, 179. doi: 10.1186/s13075-018-1668-y

Journal - Research Article

Gosling, A. L., Boocock, J., Dalbeth, N., Harré Hindmarsh, J., Stamp, L. K., Stahl, E. A., … Matisoo-Smith, E. A., & Merriman, T. R. (2018). Mitochondrial genetic variation and gout in Māori and Pacific people living in Aotearoa New Zealand. Annals of the Rheumatic Diseases, 77(4), 571-578. doi: 10.1136/annrheumdis-2017-212416

Journal - Research Article

Ketharnathan, S., Leask, M., Boocock, J., Phipps-Green, A. J., Antony, J., O'Sullivan, J. M., Merriman, T. R., & Horsfield, J. A. (2018). A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression. Human Molecular Genetics, 27(22), 3964-3973. doi: 10.1093/hmg/ddy295

Journal - Research Article

Krishnan, M., Major, T. J., Topless, R. K., Dewes, O., Yu, L., Thompson, J. M. D., … Stamp, L. K., … Wilcox, P., Grattan, D., … Merriman, T. R. (2018). Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Māori and Pacific (Polynesian) people living in Aotearoa/New Zealand. Diabetologia, 61(7), 1603-1613. doi: 10.1007/s00125-018-4623-1

Journal - Research Article

Lacey, C. J., Doudney, K., Bridgman, P. G., George, P. M., Mulder, R. T., Zarifeh, J. J., Kimber, B., Cadzow, M. J., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2018). Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy. Scientific Reports, 8, 7548. doi: 10.1038/s41598-018-25827-5

Journal - Research Article

Major, T. J., Topless, R. K., Dalbeth, N., & Merriman, T. R. (2018). Evaluation of the diet wide contribution to serum urate levels: Meta-analysis of population based cohorts. BMJ, 363, k3951. doi: 10.1136/bmj.k3951

Journal - Research Article

Manning, P. J., Grattan, D., Merriman, T., Manning, T., Williams, S., & Sutherland, W. (2018). Pharmaceutical interventions for weight-loss maintenance: No effect from cabergoline. International Journal of Obesity, 42, 1871-1879. doi: 10.1038/s41366-018-0165-3

Journal - Research Article

Pirro, M., Bianconi, V., Schiaroli, E., Francisci, D., Mannarino, M. R., Bagaglia, F., … Merriman, T., & Baldelli, F. (2018). Elevated serum uric acid levels are associated with endothelial dysfunction in HIV patients receiving highly-active antiretroviral therapy. Atherosclerosis, 272, 101-107. doi: 10.1016/j.atherosclerosis.2018.03.031

Journal - Research Article

Roberts, R. L., Wallace, M. C., Harrison, A. A., White, D., Dalbeth, N., Stamp, L. K., … Highton, J., Merriman, T. R., … Stebbings, S. M. (2018). Association of Crohn's disease-related chromosome 1q32 with ankylosing spondylitis is independent of bowel symptoms and faecal calprotectin. PeerJ, 6, e5088. doi: 10.7717/peerj.5088

Journal - Research Article

Sew Hoy, W., Antoun, J., Lin, W., Chandler, N., Merriman, T., & Farella, M. (2018). Ecological momentary assessment of pain in adolescents undergoing orthodontic treatment using a smartphone app. Seminars in Orthodontics, 24(2), 209-216. doi: 10.1053/j.sodo.2018.04.002

Journal - Research Article

Sun, M., Vazquez, A. I., Reynolds, R. J., Singh, J. A., Reeves, M., Merriman, T. R., … de los Campos, G. (2018). Untangling the complex relationships between incident gout risk, serum urate, and its comorbidities. Arthritis Research & Therapy, 20(1), 90. doi: 10.1186/s13075-018-1558-3

Journal - Research Article

Ton, K. N. T., Cree, S. L., Gronert-Sum, S. J., Merriman, T. R., Stamp, L. K., & Kennedy, M. A. (2018). Multiplexed nanopore sequencing of HLA-B locus in Māori and Pacific Island samples. Frontiers in Genetics, 9, 152. doi: 10.3389/fgene.2018.00152

Journal - Research Article

Wan Taib, W. R., Adanan, M., Yunus, N. M., Lin, T. H., Ghazali, W. S. W., Phipps-Green, A. J., & Merriman, T. R. (2018). Association of solute carrier family 2, member 9 (SLC2A9) genetic variant rs3733591 with gout in a Malay sample set. Medical Journal of Malaysia, 73(5), 307-310.

Journal - Research Article

Wright, D. F. B., Dalbeth, N., Phipps-Green, A. J., Merriman, T. R., Barclay, M. L., Drake, J., … Stamp, L. K. (2018). The impact of diuretic use and ABCG2 genotype on the predictive performance of a published allopurinol dosing tool. British Journal of Clinical Pharmacology, 84(5), 937-943. doi: 10.1111/bcp.13516

Journal - Research Article

Al-Ani, A. H., Antoun, J. S., Thomson, W. M., Merriman, T. R., & Farella, M. (2017). Maternal smoking during pregnancy is associated with offspring hypodontia. Journal of Dental Research, 96(9), 1014-1019. doi: 10.1177/0022034517711156

Journal - Research Article

Antoun, J. S., Thomson, W. M., Merriman, T. R., & Farella, M. (2017). Self-reported oral behaviour habits in hyperdivergent and normodivergent facial types. Journal of Oral Rehabilitation, 44(1), 16-21. doi: 10.1111/joor.12452

Journal - Research Article

Antoun, J. S., Thomson, W. M., Merriman, T. R., Rongo, R., & Farella, M. (2017). Impact of skeletal divergence on oral health-related quality of life and self-reported jaw function. Korean Journal of Orthodontics, 47(3), 186-194. doi: 10.4041/kjod.2017.47.3.186

Journal - Research Article

Cadzow, M., Merriman, T. R., & Dalbeth, N. (2017). Performance of gout definitions for genetic epidemiological studies: Analysis of UK Biobank. Arthritis Research & Therapy, 19(1), 181. doi: 10.1186/s13075-017-1390-1

Journal - Research Article

Cleophas, M. C., Joosten, L. A., Stamp, L. K., Dalbeth, N., Woodward, O. M., & Merriman, T. R. (2017). ABCG2 polymorphisms in gout: Insights into disease susceptibility and treatment approaches. Pharmacogenomics & Personalized Medicine, 10, 129-142. doi: 10.2147/pgpm.s105854

Journal - Research Article