Journal - Research Article

Shen, X., Wang, C., Liang, N., Liu, Z., Li, X., Zhu, Z.-J., … Merriman, T. R., … Yin, H. (2021). Serum metabolomics identifies dysregulated pathways and potential metabolic biomarkers for hyperuricemia and gout. Arthritis & Rheumatology. Advance online publication. doi: 10.1002/art.41733

Li, X., Sun, W., Lu, J., He, Y., Chen, Y., Ren, W., … Merriman, T. R., & Li, C. (2021). Effects of fenofibrate therapy on renal function in primary gout patients. Rheumatology. Advance online publication. doi: 10.1093/rheumatology/keab231

Reynolds, R. J., Irvin, M. R., Bridges, S. L., Kim, H., Merriman, T. R., Arnett, D. K., … Vazquez, A. I. (2021). Genetic correlations between traits associated with hyperuricemia, gout, and comorbidities. European Journal of Human Genetics. Advance online publication. doi: 10.1038/s41431-021-00830-z

Dalbeth, N., Horne, A., Mihov, B., Stewart, A., Gamble, G. D., Merriman, T. R., Stamp, L. K., & Reid, I. R. (2021). Elevated urate does not alter bone turnover markers: Randomized controlled trial of inosine supplementation in post-menopausal women. Arthritis & Rheumatology. Advance online publication. doi: 10.1002/art.41691

Narang, R. K., Gamble, G. G., Topless, R., Cadzow, M., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2021). Assessing the relationship between serum urate and urolithiasis using Mendelian randomization: An analysis of the UK Biobank. American Journal of Kidney Diseases. Advance online publication. doi: 10.1053/j.ajkd.2020.11.018

Topless, R. K. G., Major, T. J., Florez, J. C., Hirschhorn, J. N., Cadzow, M., Dalbeth, N., Stamp, L. K., Wilcox, P. L., … Merriman, T. R. (2021). The comparative effect of exposure to various risk factors on the risk of hyperuricaemia: Diet has a weak causal effect. Arthritis Research & Therapy, 23(1), 75. doi: 10.1186/s13075-021-02444-8

Wiggins, G. A. R., Black, M. A., Dunbier, A., Merriman, T. R., Pearson, J. F., & Walker, L. C. (2021). Variable expression quantitative trait loci analysis of breast cancer risk variants. Scientific Reports, 11(1), 7192. doi: 10.1038/s41598-021-86690-5

Tai, V., Narang, R. K., Gamble, G., Cadzow, M., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2020). Do serum urate-associated genetic variants differentially contribute to gout risk according to body mass index? Analysis of the UK Biobank. Arthritis & Rheumatology, 72(7), 1184-1191. doi: 10.1002/art.41219

Winbo, A., Earle, N., Marcondes, L., Crawford, J., Prosser, D. O., Love, D. R., Merriman, T. R., Cadzow, M., … Skinner, J. R. (2020). Genetic testing in Polynesian long QT syndrome probands reveals a lower diagnostic yield and an increased prevalence of rare variants. Heart Rhythm, 17(8), 1304-1311. doi: 10.1016/j.hrthm.2020.03.015

Takei, R., Cadzow, M., Markie, D., Bixley, M., Phipps-Green, A., Major, T. J., … Stamp, L. K., … Merriman, T. R., & Wei, W.-H. (2020). Trans-ancestral dissection of urate- and gout-associated major loci SLC2A9 and ABCG2 reveals primate-specific regulatory effects. Journal of Human Genetics. Advance online publication. doi: 10.1038/s10038-020-0821-z

Bodofsky, S., Merriman, T. R., Thomas, T. J., & Schlesinger, N. (2020). Advances in our understanding of gout as an auto-inflammatory disease. Seminars in Arthritis & Rheumatism, 50, 1089-1100. doi: 10.1016/j.semarthrit.2020.06.015

Klück, V., van Deuren, R. C., Cavalli, G., Shaukat, A., Arts, P., Cleophas, M. C., … Stamp, L. K., … Merriman, T. R., … Joosten, L. A. B. (2020). Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout. Annals of the Rheumatic Diseases, 79(4), 536-544. doi: 10.1136/annrheumdis-2019-216233

Zaidi, F., Narang, R. K., Phipps-Green, A., Gamble, G. G., Tausche, A.-K., So, A., … Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2020). Systematic genetic analysis of early-onset gout: ABCG2 is the only associated locus. Rheumatology, 59, 2544-2549. doi: 10.1093/rheumatology/kez685

Narang, R. K., Gamble, G., Phipps-Green, A. J., Topless, R., Cadzow, M., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2020). Do serum urate-associated genetic variants influence gout risk in people on diuretics? Analysis of the UK Biobank. Journal of Rheumatology, 47, 1704-1711. doi: 10.3899/jrheum.191005

Chen, H., Zhao, L., Liu, F., Chen, S., Hu, Z., Chen, L., … Merriman, T. R., & Min, J. Z. (2020). Urate in fingernail represents the deposition of urate burden in gout patients. Scientific Reports, 10, 15575. doi: 10.1038/s41598-020-72505-6

Chung, P., Logge, W. B., Riordan, B. C., Haber, P. S., Merriman, M. E., Phipps-Green, A., Topless, R. K., Merriman, T. R., Conner, T., & Morley, K. C. (2020). Genetic polymorphisms on OPRM1, DRD2, DRD4, and COMT in young adults: Lack of association with alcohol consumption. Frontiers in Psychiatry, 11, 549429. doi: 10.3389/fpsyt.2020.549429

Boocock, J., Leask, M., Okada, Y., Asian Genetic Epidemiology Network (AGEN) Consortium, Matsuo, H., Shi, Y., … Cadzow, M., Gosling, A. L., Major, T. J., Horsfield, J. A., … Merriman, T. R. (2020). Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control. Human Molecular Genetics, 29(6), 923-943. doi: 10.1093/hmg/ddaa013

Hoque, K. M., Dixon, E. E., Lewis, R. M., Allan, J., Gamble, G. D., Phipps-Green, A. J., … Stamp, L. K., Merriman, T. R., … Woodward, O. M. (2020). The ABCG2 Q141K hyperuricemia and gout associated variant illuminates the physiology of human urate excretion. Nature Communications, 11, 2767. doi: 10.1038/s41467-020-16525-w

Morgan, B. M., Brown, A. N., Deo, N., Harrop, T. W. R., Taiaroa, G., Mace, P. D., Wilbanks, S. M., Merriman, T. R., Williams, M. J. A., & McCormick, S. P. A. (2020). Nonsynonymous SNPs in LPA homologous to plasminogen deficiency mutants represent novel null apo(a) alleles. Journal of Lipid Research, 61, 432-444. doi: 10.1194/jlr.M094540

Nakayama, A., Nakatochi, M., Kawamura, Y., Yamamoto, K., Nakaoka, H., Shimizu, S., … Major, T. J., Merriman, T. R., … on behalf of Japan Gout Genomics Consortium (Japan Gout). (2020). Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients. Annals of the Rheumatic Diseases, 79, 657-665. doi: 10.1136/annrheumdis-2019-216644

Wang, Z., Zhao, Y., Phipps-Green, A., Liu-Bryan, R., Ceponis, A., Boyle, D. L., … Merriman, T. R., … Terkeltaub, R. (2020). Differential DNA methylation of networked signaling, transcriptional, innate and adaptive immunity, and osteoclastogenesis genes and pathways in gout. Arthritis & Rheumatology, 72(5), 802-814. doi: 10.1002/art.41173

Metcalfe, L. K., Krishnan, M., Turner, N., Yaghootkar, H., Merry, T. L., Dewes, O., … Stamp, L. K., Merriman, T. R., … Murphy, R. (2020). The Māori and Pacific specific CREBRF variant and adult height. International Journal of Obesity, 44, 748-752. doi: 10.1038/s41366-019-0437-6

Stamp, L. K., Chapman, P. T., Barclay, M., Horne, A., Frampton, C., Merriman, T. R., Wright, D. F. B., … Dalbeth, N. (2020). Relationships between allopurinol dose, oxypurinol concentration and urate-lowering response: In search of a minimum effective oxypurinol concentration. Clinical & Translational Science, 13, 110-115. doi: 10.1111/cts.12686

Leask, M. P., Sumpter, N. A., Lupi, A. S., Vazquez, A. I., Reynolds, R. J., Mount, D. B., & Merriman, T. R. (2020). The shared genetic basis of hyperuricemia, gout, and kidney function. Seminars in Nephrology, 40(6), 586-599. doi: 10.1016/j.semnephrol.2020.12.002

Xue, X., Liu, Z., Li, X., Lu, J., Wang, C., Wang, X., … Merriman, T. R., … Cui, L. (2020). The efficacy and safety of citrate mixture vs sodium bicarbonate on urine alkalization in Chinese primary gout patients with benzbromarone: A prospective, randomized controlled study. Rheumatology. Advance online publication. doi: 10.1093/rheumatology/keaa668

Wrigley, R., Phipps-Green, A. J., Topless, R. K., Major, T. J., Cadzow, M., Riches, P., … Stamp, L. K., … Merriman, T. R. (2020). Pleiotropic effect of the ABCG2 gene in gout: Involvement in serum urate levels and progression from hyperuricemia to gout. Arthritis Research & Therapy, 22, 45. doi: 10.1186/s13075-020-2136-z

Al-Ani, A. H., Antoun, J. S., Thomson, W. M., Merriman, T. R., & Farella, M. (2020). Common variants of EDA are associated with non-syndromic hypodontia. Orthodontics & Craniofacial Research. Advance online publication. doi: 10.1111/ocr.12419

Krishnan, M., Murphy, R., Okesene-Gafa, K. A. M., Ji, M., Thompson, J. M. D., Taylor, R. S., Merriman, T. R., … McKinlay, C. J. D. (2020). The Pacific-specific CREBRF rs373863828 allele protects against gestational diabetes mellitus in Māori and Pacific women with obesity. Diabetologia. Advance online publication. doi: 10.1007/s00125-020-05202-8

Gao, Q., Cheng, X., Merriman, T. R., Wang, C., Cui, L., Zhang, H., … Lu, J. (2020). Trends in the manifestations of 9754 gout patients in a Chinese clinical center: A 10-year observational study. Joint Bone Spine. Advance online publication. doi: 10.1016/j.jbspin.2020.09.010

Lu, J., Sun, M., Wu, X., Yuan, X., Liu, Z., Qu, X., … Merriman, T. R., & Li, C. (2019). Urate-lowering therapy alleviates atherosclerosis inflammatory response factors and neointimal lesions in a mouse model of induced carotid atherosclerosis. FEBS Journal, 286, 1346-1359. doi: 10.1111/febs.14768

Lu, J., Dalbeth, N., Yin, H., Li, C., Merriman, T. R., & Wei, W.-H. (2019). Mouse models for human hyperuricaemia: A critical review. Nature Reviews Rheumatology, 15, 413-426. doi: 10.1038/s41584-019-0222-x

Kawamura, Y., Nakaoka, H., Nakayama, A., Okada, Y., Yamamoto, K., Higashino, T., … Merriman, T. R., … Matsuo, H. (2019). Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout. Annals of the Rheumatic Diseases, 78, 1430-1437. doi: 10.1136/annrheumdis-2019-215521

Jordan, D. M., Choi, H. K., Verbanck, M., Topless, R., Won, H.-H., Nadkarni, G., Merriman, T. R., & Do, R. (2019). No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study. PLoS Medicine, 16(1), e1002725. doi: 10.1371/journal.pmed.1002725

Vazirpanah, N., Ottria, A., van der Linden, M., Wichers, C. G. K., Schuiveling, M., van Lochem, E., Phipps-Green, A., Merriman, T., … Broen, J. C. A. (2019). mTOR inhibition by metformin impacts monosodium urate crystal-induced inflammation and cell death in gout: A prelude to a new add-on therapy? Annals of the Rheumatic Diseases, 78, 663-671. doi: 10.1136/annrheumdis-2018-214656

Murphy, R., Gamble, G. D., House, M., Pool, B., Horne, A., Merriman, T. R., & Dalbeth, N. (2019). Greater insulin response to acute fructose ingestion among Māori and Pacific people compared to European people living in Aotearoa New Zealand. Internal Medicine Journal, 49, 196-202. doi: 10.1111/imj.14135

Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., … Bixley, M. J., … Merriman, T. R., … Wilson, J. F. (2019). Associations of autozygosity with a broad range of human phenotypes. Nature Communications, 10, 4957. doi: 10.1038/s41467-019-12283-6

Leask, M., Dowdle, A., Salvesen, H., Topless, R., Fadason, T., Wei, W., … Marsman, J., Antony, J., … Merriman, T. R., & Horsfield, J. A. (2019). Functional urate-associated genetic variants influence expression of lincRNAs LINC01229 and MAFTRR. Frontiers in Genetics, 9, 733. doi: 10.3389/fgene.2018.00733

Pirro, M., Bianconi, V., Schiaroli, E., Francisci, D., Mannarino, M. R., Bagaglia, F., … Merriman, T., & Baldelli, F. (2018). Elevated serum uric acid levels are associated with endothelial dysfunction in HIV patients receiving highly-active antiretroviral therapy. Atherosclerosis, 272, 101-107. doi: 10.1016/j.atherosclerosis.2018.03.031

Wright, D. F. B., Dalbeth, N., Phipps-Green, A. J., Merriman, T. R., Barclay, M. L., Drake, J., … Stamp, L. K. (2018). The impact of diuretic use and ABCG2 genotype on the predictive performance of a published allopurinol dosing tool. British Journal of Clinical Pharmacology, 84(5), 937-943. doi: 10.1111/bcp.13516

Gosling, A. L., Boocock, J., Dalbeth, N., Harré Hindmarsh, J., Stamp, L. K., Stahl, E. A., … Matisoo-Smith, E. A., & Merriman, T. R. (2018). Mitochondrial genetic variation and gout in Māori and Pacific people living in Aotearoa New Zealand. Annals of the Rheumatic Diseases, 77(4), 571-578. doi: 10.1136/annrheumdis-2017-212416

Conner, T. S., McFarlane, K. G., Choukri, M., Riordan, B. C., Flett, J. A. M., Phipps-Green, A. J., Topless, R. K., Merriman, M. E., & Merriman, T. R. (2018). The oxytocin receptor gene (OXTR) variant rs53576 is not related to emotional traits or states in young adults [Brief research report]. Frontiers in Psychology, 9, 2548. doi: 10.3389/fpsyg.2018.02548

Sew Hoy, W., Antoun, J., Lin, W., Chandler, N., Merriman, T., & Farella, M. (2018). Ecological momentary assessment of pain in adolescents undergoing orthodontic treatment using a smartphone app. Seminars in Orthodontics, 24(2), 209-216. doi: 10.1053/j.sodo.2018.04.002

Wan Taib, W. R., Adanan, M., Yunus, N. M., Lin, T. H., Ghazali, W. S. W., Phipps-Green, A. J., & Merriman, T. R. (2018). Association of solute carrier family 2, member 9 (SLC2A9) genetic variant rs3733591 with gout in a Malay sample set. Medical Journal of Malaysia, 73(5), 307-310.

Lacey, C. J., Doudney, K., Bridgman, P. G., George, P. M., Mulder, R. T., Zarifeh, J. J., Kimber, B., Cadzow, M. J., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2018). Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy. Scientific Reports, 8, 7548. doi: 10.1038/s41598-018-25827-5

Fatima, T., McKinney, C., Major, T. J., Stamp, L. K., Dalbeth, N., Iverson, C., Merriman, T. R., & Miner, J. N. (2018). The relationship between ferritin and urate levels and risk of gout. Arthritis Research & Therapy, 20, 179. doi: 10.1186/s13075-018-1668-y

Krishnan, M., Major, T. J., Topless, R. K., Dewes, O., Yu, L., Thompson, J. M. D., … Stamp, L. K., … Wilcox, P., Grattan, D., … Merriman, T. R. (2018). Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Māori and Pacific (Polynesian) people living in Aotearoa/New Zealand. Diabetologia, 61(7), 1603-1613. doi: 10.1007/s00125-018-4623-1

Ketharnathan, S., Leask, M., Boocock, J., Phipps-Green, A. J., Antony, J., O'Sullivan, J. M., Merriman, T. R., & Horsfield, J. A. (2018). A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression. Human Molecular Genetics, 27(22), 3964-3973. doi: 10.1093/hmg/ddy295

Roberts, R. L., Wallace, M. C., Harrison, A. A., White, D., Dalbeth, N., Stamp, L. K., … Highton, J., Merriman, T. R., … Stebbings, S. M. (2018). Association of Crohn's disease-related chromosome 1q32 with ankylosing spondylitis is independent of bowel symptoms and faecal calprotectin. PeerJ, 6, e5088. doi: 10.7717/peerj.5088

Fanning, N., Merriman, T. R., Dalbeth, N., & Stamp, L. K. (2018). An association of smoking with serum urate and gout: A health paradox. Seminars in Arthritis & Rheumatism, 47(6), 825-842. doi: 10.1016/j.semarthrit.2017.11.004

Sun, M., Vazquez, A. I., Reynolds, R. J., Singh, J. A., Reeves, M., Merriman, T. R., … de los Campos, G. (2018). Untangling the complex relationships between incident gout risk, serum urate, and its comorbidities. Arthritis Research & Therapy, 20(1), 90. doi: 10.1186/s13075-018-1558-3

Manning, P. J., Grattan, D., Merriman, T., Manning, T., Williams, S., & Sutherland, W. (2018). Pharmaceutical interventions for weight-loss maintenance: No effect from cabergoline. International Journal of Obesity, 42, 1871-1879. doi: 10.1038/s41366-018-0165-3

Major, T. J., Topless, R. K., Dalbeth, N., & Merriman, T. R. (2018). Evaluation of the diet wide contribution to serum urate levels: Meta-analysis of population based cohorts. BMJ, 363, k3951. doi: 10.1136/bmj.k3951

Ton, K. N. T., Cree, S. L., Gronert-Sum, S. J., Merriman, T. R., Stamp, L. K., & Kennedy, M. A. (2018). Multiplexed nanopore sequencing of HLA-B locus in Māori and Pacific Island samples. Frontiers in Genetics, 9, 152. doi: 10.3389/fgene.2018.00152

Tanner, C., Boocock, J., Stahl, E. A., Dobbyn, A., Mandal, A. K., Cadzow, M., Phipps-Green, A. J., Topless, R. K., … Stamp, L. K., … Merriman, T. R. (2017). Population specific resequencing associates the ATP binding cassette subfamily C member 4 (ABCC4) gene with gout in New Zealand Māori and Pacific men. Arthritis & Rheumatology, 69(7), 1461-1469. doi: 10.1002/art.40110

Antoun, J. S., Thomson, W. M., Merriman, T. R., Rongo, R., & Farella, M. (2017). Impact of skeletal divergence on oral health-related quality of life and self-reported jaw function. Korean Journal of Orthodontics, 47(3), 186-194. doi: 10.4041/kjod.2017.47.3.186

Morton, S. E., O'Hare, K. J. M., Maha, J. L. K., Nicolson, M. P., Machado, L., Topless, R., Merriman, T. R., & Linscott, R. J. (2017). Testing the validity of taxonic schizotypy using genetic and environmental risk variables. Schizophrenia Bulletin, 43(3), 633-643. doi: 10.1093/schbul/sbw108

Rasheed, H., Stamp, L. K., Dalbeth, N., & Merriman, T. R. (2017). Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout. Arthritis Research & Therapy, 19, 161. doi: 10.1186/s13075-017-1369-y

Merriman, T. (2017). Genomic Influences on hyperuricemia and gout. Rheumatic Disease Clinics of North America, 43(3), 389-399. doi: 10.1016/j.rdc.2017.04.004

Dalbeth, N., Allan, J., Gamble, G. D., Phipps-Green, A., Flynn, T. J., Mihov, B., … Stamp, L. K., & Merriman, T. R. (2017). Influence of genetic variants on renal uric acid handling in response to frusemide: An acute intervention study. RMD Open, 3(1), e000424. doi: 10.1136/rmdopen-2016-000424

Cleophas, M. C., Joosten, L. A., Stamp, L. K., Dalbeth, N., Woodward, O. M., & Merriman, T. R. (2017). ABCG2 polymorphisms in gout: Insights into disease susceptibility and treatment approaches. Pharmacogenomics & Personalized Medicine, 10, 129-142. doi: 10.2147/pgpm.s105854

Al-Ani, A. H., Antoun, J. S., Thomson, W. M., Merriman, T. R., & Farella, M. (2017). Maternal smoking during pregnancy is associated with offspring hypodontia. Journal of Dental Research, 96(9), 1014-1019. doi: 10.1177/0022034517711156

Jones, G. T., Tromp, G., Kuivaniemi, H., Gretarsdottir, S., Baas, A. F., Giusti, B., … Phillips, L. V., Williams, M. J. A., Wei, W., … Thomson, I. A., Krysa, J., Hill, G. B., Roake, J., Merriman, T. R., … van Rij, A., … Bown, M. J. (2017). Meta-analysis of genome-wide association studies for abdominal aortic aneurysm identifies four new disease-specific risk loci. Circulation Research, 120, 341-353. doi: 10.1161/circresaha.116.308765

Stiburkova, B., Pavelcova, K., Zavada, J., Petru, L., Simek, P., Cepek, P., … Merriman, T. R., & Pavelka, K. (2017). Functional non-synonymous variants of ABCG2 and gout risk. Rheumatology, 56(11), 1982-1992. doi: 10.1093/rheumatology/kex295

Cadzow, M., Merriman, T. R., & Dalbeth, N. (2017). Performance of gout definitions for genetic epidemiological studies: Analysis of UK Biobank. Arthritis Research & Therapy, 19(1), 181. doi: 10.1186/s13075-017-1390-1

He, W., Phipps-Green, A., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2017). Population-specific association between ABCG2 variants and tophaceous disease in people with gout. Arthritis Research & Therapy, 19(1), 43. doi: 10.1186/s13075-017-1254-8

Antoun, J. S., Thomson, W. M., Merriman, T. R., & Farella, M. (2017). Self-reported oral behaviour habits in hyperdivergent and normodivergent facial types. Journal of Oral Rehabilitation, 44(1), 16-21. doi: 10.1111/joor.12452

Wei, W.-H., Viatte, S., Merriman, T. R., Barton, A., & Worthington, J. (2017). Genotypic variability based association identifies novel non-additive loci DHCR7 and IRF4 in sero-negative rheumatoid arthritis. Scientific Reports, 7(1), 5261. doi: 10.1038/s41598-017-05447-1

Vazirpanah, N., Kienhorst, L. B. E., Van Lochem, E., Wichers, C., Rossato, M., Shiels, P. G., … Stamp, L. K., Merriman, T. R., … Broen, J. C. A. (2017). Patients with gout have short telomeres compared with healthy participants: Association of telomere length with flare frequency and cardiovascular disease in gout. Annals of the Rheumatic Diseases, 76(7), 1309-1315. doi: 10.1136/annrheumdis-2016-210538

Nakayama, A., Nakaoka, H., Yamamoto, K., Sakiyama, M., Shaukat, A., Toyoda, Y., … Stamp, L. K., … Merriman, T. R., & Matsuo, H. (2017). GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes. Annals of the Rheumatic Diseases, 76(5), 869-877. doi: 10.1136/annrheumdis-2016-209632

Todd, A. S., Walker, R. J., MacGinley, R. J., Kelly, J., Merriman, T. R., Major, T. J., & Johnson, R. J. (2017). Dietary sodium modifies serum uric acid concentrations in humans. American Journal of Hypertension, 30(12), 1196-1202. doi: 10.1093/ajh/hpx123

De Smit, E., Clarke, L., Sanfilippo, P. G., Merriman, T. R., Brown, M. A., Hill, C. L., … Giant Cell Arteritis Pathology Network. (2017). Geo-epidemiology of temporal artery biopsy-positive giant cell arteritis in Australia and New Zealand: Is there a seasonal influence? RMD Open, 3(2), e000531. doi: 10.1136/rmdopen-2017-000531

Higashino, T., Takada, T., Nakaoka, H., Toyoda, Y., Stiburkova, B., Miyata, H., … Merriman, T. R., … Matsuo, H. (2017). Multiple common and rare variants of ABCG2 cause gout. RMD Open, 3(2), e000464. doi: 10.1136/rmdopen-2017-000464

Pirro, M., Mannarino, M. R., Bianconi, V., De Vuono, S., Sahebkar, A., Bagaglia, F., … Merriman, T. (2017). Uric acid and bone mineral density in postmenopausal osteoporotic women: The link lies within the fat. Osteoporosis International, 28(3), 973-981. doi: 10.1007/s00198-016-3792-3

Roberts, R. L., Wallace, M. C., Phipps-Green, A. J., Topless, R., Drake, J. M., Tan, P., … Merriman, T. R., & Stamp, L. K. (2017). ABCG2 loss-of-function polymorphism predicts poor response to allopurinol in patients with gout. Pharmacogenomics Journal, 17, 201-203. doi: 10.1038/tpj.2015.101

van 't Hof, F. N. G., Ruigrok, Y. M., Lee, C. H., Ripke, S., Anderson, G., de Andrade, M., … Jones, G. T., … van Rij, A. M., … Vascular Research Consortium of New Zealand, including Phillips, L. V., Hill, G. B., Williams, M. J. A., Thomson, I. A., Krysa, J., Wilkins, G. T., Merriman, T. R., Lewis, D. R., … de Bakker, P. I. W. (2016). Shared genetic risk factors of intracranial, abdominal, and thoracic aneurysms. Journal of the American Heart Association, 5(7), e002603. doi: 10.1161/jaha.115.002603

Wright, D. F. B., Duffull, S. B., Merriman, T. R., Dalbeth, N., Barclay, M. L., & Stamp, L. K. (2016). Predicting allopurinol response in patients with gout. British Journal of Clinical Pharmacology, 81(2), 277-289. doi: 10.1111/bcp.12799

Rasheed, H., McKinney, C., Stamp, L. K., Dalbeth, N., Topless, R. K., Day, R., … Merriman, T. R. (2016). The toll-like receptor 4 (TLR4) variant rs2149356 and risk of gout in European and Polynesian sample sets. PLoS ONE, 11(1), e0147939. doi: 10.1371/journal.pone.0147939

Dalbeth, N., Merriman, T. R., & Stamp, L. K. (2016). Gout. Lancet, 388(10055), 2039-2052. doi: 10.1016/S0140-6736(16)00346-9

Phipps-Green, A. J., Merriman, M. E., Topless, R., Altaf, S., Montgomery, G. W., Franklin, C., Jones, G. T., van Rij, A. M., … Stamp, L. K., … Merriman, T. R. (2016). Twenty-eight loci that influence serum urate levels: Analysis of association with gout. Annals of the Rheumatic Diseases, 75, 124-130. doi: 10.1136/annrheumdis-2014-205877

Rasheed, H., Phipps-Green, A. J., Topless, R., Smith, M. D., Hill, C., Lester, S., … van Rij, A., Jones, G. T., McCormick, S. P., Harrison, A. A., Stamp, L. K., … Merriman, T. R. (2016). Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout. Rheumatology, 55(8), 1421-1430. doi: 10.1093/rheumatology/kew057

Fatima, T., Altaf, S., Phipps-Green, A., Topless, R., Flynn, T. J., Stamp, L. K., … Merriman, T. R. (2016). Association analysis of the beta-3 adrenergic receptor Trp64Arg (rs4994) polymorphism with urate and gout. Rheumatology International, 36(2), 255-261. doi: 10.1007/s00296-015-3370-6

Nguyen, H. T., Boocock, J., Merriman, T. R., & Black, M. A. (2016). SRBreak: A read-depth and split-read framework to identify breakpoints of different events inside simple copy-number variable regions. Frontiers in Genetics, 7, 160. doi: 10.3389/fgene.2016.00160

Azevedo, P. M., Merriman, T. R., Topless, R. K., Wilson, N. J., Crengle, S., & Lennon, D. R. (2016). Association study involving polymorphisms in IL-6, IL-1RA, and CTLA4 genes and rheumatic heart disease in New Zealand population of Māori and Pacific ancestry. Cytokine, 85, 201-206. doi: 10.1016/j.cyto.2016.06.029

Robinson, P. C., Choi, H. K., Do, R., & Merriman, T. R. (2016). Insight into rheumatological cause and effect through the use of Mendelian randomization. Nature Reviews Rheumatology, 12, 486-496. doi: 10.1038/nrrheum.2016.102

Kannangara, D. R. W., Phipps-Green, A. J., Dalbeth, N., Stamp, L. K., Williams, K. M., Graham, G. G., … Merriman, T. R. (2016). Hyperuricaemia: Contributions of urate transporter ABCG2 and the fractional renal clearance of urate. Annals of the Rheumatic Diseases, 75, 1363-1366. doi: 10.1136/annrheumdis-2015-208111

Cadzow, M., Merriman, T. R., Boocock, J., Dalbeth, N., Stamp, L. K., Black, M. A., … Wilcox, P. L. (2016). Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A. BMC Medical Genetics, 17, 80. doi: 10.1186/s12881-016-0341-z

Mitnala, S., Phipps-Green, A., Franklin, C., Horne, A., Stamp, L. K., Merriman, T. R., & Dalbeth, N. (2016). Clinical and genetic features of diuretic-associated gout: A case-control study. Rheumatology, 55(7), 1172-1176. doi: 10.1093/rheumatology/kew018

Roberts, R. L., Wallace, M. C., Harrison, A., Dalbeth, N., Merriman, T. R., & Stamp, L. K. (2015). A human leukocyte antigen locus haplotype confers risk for allopurinol-related adverse effects in Caucasian patients with gout. Pharmacogenetics & Genomics, 25(8), 412-415. doi: 10.1097/fpc.0000000000000147

Dalbeth, N., Phipps-Green, A., House, M. E., Gamble, G. D., Horne, A., Stamp, L. K., & Merriman, T. R. (2015). Body mass index modulates the relationship of sugar-sweetened beverage intake with serum urate concentrations and gout. Arthritis Research & Therapy, 17(1), 263. doi: 10.1186/s13075-015-0781-4

Perez-Ruiz, F., Aniel-Quiroga, M. A., Herrero-Beites, A. M., Chinchilla, S. P., Erauskin, G. G., & Merriman, T. (2015). Renal clearance of uric acid is linked to insulin resistance and lower excretion of sodium in gout patients. Rheumatology International, 35(9), 1519-1524. doi: 10.1007/s00296-015-3242-0

Gosling, A. L., Buckley, H. R., Matisoo-Smith, E., & Merriman, T. R. (2015). Pacific populations, metabolic disease and 'just-so stories': A critique of the 'Thrifty Genotype' hypothesis in Oceania. Annals of Human Genetics, 79(6), 470-480. doi: 10.1111/ahg.12132

Merriman, T. R. (2015). An update on the genetic architecture of hyperuricemia and gout. Arthritis Research & Therapy, 17, 98. doi: 10.1186/s13075-015-0609-2

Kienhorst, L. B. E., van Lochem, E., Kievit, W., Dalbeth, N., Merriman, M. E., Phipps-Green, A., … Stamp, L. K., … Merriman, T. R., … Radstake, T. R. D. J. (2015). Gout is a chronic inflammatory disease in which high levels of interleukin 8 (CXCL8), myeloid-related protein 8/myeloid-related protein14 complex, and an altered proteome are associated with diabetes mellitus and cardiovascular disease. Arthritis & Rheumatology, 67(12), 3303-3313. doi: 10.1002/art.39318

Topless, R. K., Flynn, T. J., Cadzow, M., Stamp, L. K., Dalbeth, N., Black, M. A., & Merriman, T. R. (2015). Association of SLC2A9 genotype with phenotypic variability of serum urate in pre-menopausal women. Frontiers in Genetics, 6, 313. doi: 10.3389/fgene.2015.00313

Murphy, R., Thornley, S., de Zoysa, J., Stamp, L. K., Dalbeth, N., & Merriman, T. R. (2015). Sugar sweetened beverage consumption among adults with gout or type 2 diabetes. PLoS ONE, 10(5), e0125543. doi: 10.1371/journal.pone.0125543

Johnson, R. J., Merriman, T., & Lanaspa, M. A. (2015). Causal or noncausal relationship of uric acid with diabetes. Diabetes, 64(8), 2720-2722. doi: 10.2337/db15-0532

Doecke, J. D., Simms, L. A., Zhao, Z. Z., Roberts, R. L., Fowler, E. V., Croft, A., … Barclay, M. L., Merriman, T. R., Gearry, R. B., … Radford-Smith, G. L. (2015). Smoking behaviour modifies IL23r-associated disease risk in patients with Crohn's disease. Journal of Gastroenterology & Hepatology, 30(2), 299-307. doi: 10.1111/jgh.12674

Flynn, T. J., Cadzow, M., Dalbeth, N., Jones, P. B., Stamp, L. K., Harré Hindmarsh, J., Todd, A. S., Walker, R. J., Topless, R., & Merriman, T. R. (2015). Positive association of tomato consumption with serum urate: Support for tomato consumption as an anecdotal trigger of gout flares. BMC Musculoskeletal Disorders, 16, 196. doi: 10.1186/s12891-015-0661-8