Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Department of Biochemistry profile

Dr David Chyou

PositionPostdoctoral Fellow
DepartmentDepartment of Biochemistry
Research summaryBioinformatics of fungal and microbial genomes

Research

I have a PhD degree in mathematics. My research interests include both bioinformatics and genomics, particularly analysis of microbial and fungal genomes. I develop and use software to answer fundamental questions about the biology of these organisms. I also have an ongoing research interest in big-data in healthcare.

Publications

Nishtala, P. S., Gill, S., & Chyou, T.-y. (2020). Analysis of the US FDA adverse event reporting system to identify adverse cardiac events associated with hydroxychloroquine in older adults. Pharmacoepidemiology & Drug Safety. Advance online publication. doi: 10.1002/pds.5155

Nishtala, P. S., & Chyou, T.-y. (2020). Identifying drug combinations associated with acute kidney injury using association rules method. Pharmacoepidemiology & Drug Safety, 29, 467-473. doi: 10.1002/pds.4960

Chyou, T.-y., Nishtala, R., & Nishtala, P. S. (2020). Comparative risk of Parkinsonism associated with olanzapine, risperidone and quetiapine in older adults: A propensity score matched cohort study. Pharmacoepidemiology & Drug Safety, 29, 692-700. doi: 10.1002/pds.5007

Rollie, C., Chevallereau, A., Watson, B. N. J., Chyou, T.-y., Fradet, O., McLeod, I., Fineran, P. C., Brown, C. M., … Westra, E. R. (2020). Targeting of temperate phages drives loss of type I CRISPR-Cas systems. Nature, 578, 149-153. doi: 10.1038/s41586-020-1936-2

Rees, K. E., Chyou, T.-y., & Nishtala, P. S. (2020). A disproportionality analysis of the adverse drug events associated with lurasidone in paediatric patients using the US FDA Adverse Event Reporting System (FAERS) [Research Letter]. Drug Safety, 43, 607-609. doi: 10.1007/s40264-020-00928-1

Journal - Research Article

Nishtala, P. S., Gill, S., & Chyou, T.-y. (2020). Analysis of the US FDA adverse event reporting system to identify adverse cardiac events associated with hydroxychloroquine in older adults. Pharmacoepidemiology & Drug Safety. Advance online publication. doi: 10.1002/pds.5155

Rollie, C., Chevallereau, A., Watson, B. N. J., Chyou, T.-y., Fradet, O., McLeod, I., Fineran, P. C., Brown, C. M., … Westra, E. R. (2020). Targeting of temperate phages drives loss of type I CRISPR-Cas systems. Nature, 578, 149-153. doi: 10.1038/s41586-020-1936-2

Chyou, T.-y., Nishtala, R., & Nishtala, P. S. (2020). Comparative risk of Parkinsonism associated with olanzapine, risperidone and quetiapine in older adults: A propensity score matched cohort study. Pharmacoepidemiology & Drug Safety, 29, 692-700. doi: 10.1002/pds.5007

Nishtala, P. S., & Chyou, T.-y. (2020). Identifying drug combinations associated with acute kidney injury using association rules method. Pharmacoepidemiology & Drug Safety, 29, 467-473. doi: 10.1002/pds.4960

Shehreen, S., Chyou, T.-y., Fineran, P. C., & Brown, C. M. (2019). Genome-wide correlation analysis suggests different roles of CRISPR-Cas systems in the acquisition of antibiotic resistance genes in diverse species. Philosophical Transactions of the Royal Society B, 374(1772), 20180384. doi: 10.1098/rstb.2018.0384

Nishtala, P. S., Jamieson, H. A., Hanger, H. C., Chyou, T.-y., & Hilmer, S. N. (2019). Examining the risks of major bleeding events in older people using antithrombotics. Cardiovascular Drugs & Therapy, 33, 323-329. doi: 10.1007/s10557-019-06867-z

Chyou, T., & Brown, C. M. (2019). Prediction and diversity of tracrRNAs from type II CRISPR-Cas systems. RNA Biology, 16(4), 423-434. doi: 10.1080/15476286.2018.1498281

Nishtala, P. S., Chyou, T.-y., Held, F., & Le Couteur, D. G. (2018). Association rules method and big data: Evaluating frequent medication combinations associated with fractures in older adults. Pharmacoepidemiology & Drug Safety, 27(10), 1123-1130. doi: 10.1002/pds.4432

Nishtala, P. S., & Chyou, T.-y. (2017). Exploring New Zealand prescription data using sequence symmetry analyses for predicting adverse drug reactions. Journal of Clinical Pharmacy & Therapeutics, 42(2), 189-194. doi: 10.1111/jcpt.12491

Nishtala, P. S., & Chyou, T.-y. (2017). Real-world risk of diabetes with antipsychotic use in older New Zealanders: A case-crossover study. European Journal of Clinical Pharmacology, 73(2), 233-239. doi: 10.1007/s00228-016-2158-2

Nishtala, P. S., & Chyou, T.-y. (2017). Zopiclone use and risk of fractures in older people: Population-based study. Journal of the American Medical Directors Association, 18(4), 368.e1-368.e8. doi: 10.1016/j.jamda.2016.12.085

Salahudeen, M. S., Chyou, T.-y., & Nishtala, P. S. (2016). Serum anticholinergic activity and cognitive and functional adverse outcomes in older people: A systematic review and meta-analysis of the literature. PLoS ONE, 11(3), e0151084. doi: 10.1371/journal.pone.0151084

Nishtala, P. S., Gnjidic, D., Chyou, T., & Hilmer, S. N. (2016). Discontinuation of statins in a population of older New Zealanders with limited life expectancy. Internal Medicine Journal, 46(4), 493-496. doi: 10.1111/imj.13024

Chyou, T., Liddell, G. F., & Paulin, M. G. (2011). An upper-body can improve the stability and efficiency of passive dynamic walking. Journal of Theoretical Biology, 285(1), 126-135. doi: 10.1016/j.jtbi.2011.06.032

Chyou, D. T., Rawle, V. L., & Trotman, C. N. A. (2007). Quaternary structure of Artemia haemoglobin II: Analysis of T and C polymer alignment and interpolymer interface. BMC Structural Biology, 7, 26. doi: 10.1186/1472-6807-7-26

^ Top of page

Journal - Research Other

Rees, K. E., Chyou, T.-y., & Nishtala, P. S. (2020). A disproportionality analysis of the adverse drug events associated with lurasidone in paediatric patients using the US FDA Adverse Event Reporting System (FAERS) [Research Letter]. Drug Safety, 43, 607-609. doi: 10.1007/s40264-020-00928-1

Nishtala, P. S., Allore, H., Han, L., Jamieson, H. A., Hilmer, S. N., & Chyou, T.-y. (2020). Impact of anticholinergic burden on cognitive performance: A cohort study of community-dwelling older adults. Journal of the American Medical Directors Association, 21, 1357-1366. doi: 10.1016/j.jamda.2020.03.027

Christodoulos, I. N., Chyou, T.-y., & Nishtala, P. S. (2020). Safety of fluoxetine use in children and adolescents: A disproportionality analysis of the Food and Drug Administration Adverse Event Reporting System (FAERS) database. European Journal of Clinical Pharmacology. Advance online publication. doi: 10.1007/s00228-020-02970-5

Nishtala, P. S., Ndukwe, H. C., Chyou, T.-y., Salahudeen, M. S., & Narayan, S. W. (2017). An overview of pharmacoepidemiology in New Zealand: Medical databases, registries and research achievements. New Zealand Medical Journal, 130(1449), 52-61. Retrieved from https://www.nzma.org.nz/journal

More publications...