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Otago Biochemistry research in the media and elsewhere

Detecting parasites in poo

Microscopic parasites in a poo sample, viewed using Techion's device.Professor Kurt Krause comments on groundbreaking parasite-detection technology developed by Dunedin company Techion for use in human health management. Originally used to test sheep poo, these advances are based on the inventions of Dr Stephen Sowerby, developed at the Otago Department of Biochemistry and funded by the Bill and Melinda Gates Foundation.

Visit the story on the TVNZ website


Diet and genes in gout

The Gout by James Gillray in 1799: a small fierce creature with sharp teeth is biting into a swollen foot at the base of the big toe.Gout, a painful disease of the joints, is traditionally thought of as an affliction of wealthy old men who overindulge in alcohol and rich foods. 

Dr Tanya Major and Professor Tony Merriman have been crunching the numbers and finding out that genes are much more important than dietary patterns to people's risk of developing gout.

Watch Dr Major talk about this research on the TVNZ website here

You can also watch Professor Merriman talk to the Royal Society of New Zealand about how his research team uses genetics to understand the causes of gout:


Making micro-stomachs for cancer

Yasmin Nouri presenting her thesis topic in three minutes.

Yasmin Nouri, a student in Professor Parry Guilford’s group, won the Master's category of the 2018 University of Otago three minute thesis competition with this talk about making micro-stomachs to research a prevention for gastric cancer.


Freeze-thaw worms

A nematode worm photographed using a microscope.

Associate Professor Craig Marshall explains some recent research on reviving 40,000 year-old frozen nematode worms, and talks about his own research into nematodes from Antarctica that freeze and thaw every winter. (Photo: Doklady Biological Sciences)

Visit the story on the RNZ website


Revealing the mystery of New Zealand's glowworm

Screen grab from video of a glowworm in its slime hammock, glowing.

Woah! - Animals that make light! How do they do that? Dr Miriam Sharpe and Professor Kurt Krause explain their research on what makes glowworms glow on National Public Radio's Science Friday in the USA, and on New Zealand media.

Visit the story on the Science Friday website

Scientists make illuminating discovery about Kiwi glowworms. One News, TVNZ

Mystery behind glowworm's glow revealed. Newshub, TV3

Unlocking the secret of the glowworm's shine. Afternoons, RNZ


Star's mutant cancer-causing gene discovered by Otago scientist

Picture of Stan Walker from his documentary.

Twenty-one years ago, Professor Parry Guilford discovered the faulty gene that caused many members of a Tauranga family to die from stomach cancer.

Members of this family can now be tested for the mutation, and if they have it, they can choose to have their stomachs removed to prevent developing cancer. 

Singer Stan Walker is a member of this family, and the discovery that he has this mutation and his subsequent choices were recently shared in the TV3 documentary 'Stan: His Inspirational Journey' (to watch you will need to log in - see if you can spot some footage of a very young Professor Guildford at the lab bench).

Visit the story on the Otago Daily Times website and on Stuff.co.nz

Read how Professor Guilford explains his research to a stranger at a barbecue on the NZ Herald website

Watch Professor Guilford explain how cancer works, and where his research is going next, to the Cancer Society: 


How do you sequence a genome?

Scientist's face reflecting on the front of a DNA sequencing machine.

Humans have more than 3 billion DNA bases in each of their cells, containing a full set of instructions on how to build a body. How do you find out the entire sequence of this genome? Professor Peter Dearden, Dr Becky Laurie, Dr Aaron Jeffs and others talk to RNZ National's Our Changing World about how to sequence a genome.

Visit the story on the RNZ website

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How queen bees control their worker fertility

Bee apis image

Bee hives have evolved to have a complex, fascinating social hierarchy, and although we know about Royal Jelly and pheromones, how exactly does the queen bee control the fertility of the rest of the hive? Research into the molecular mechanism behind this control by Professor Peter Dearden and Drs Elizabeth Duncan and Otto Hyink has been profiled on BBC Radio 4's "Inside Science" programme.

Visit the story on the BBC's iplayer

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Squid that glow using crystals

Firefly squid glowing blue in the dark.

The Japanese firefly squid makes intense blue light to distract its predators, and is considered a great delicacy in Japan. Dr Miriam Sharpe talks about her research into the crystals that the squid uses to produce the light, and Professor Kurt Krause talks about bioluminescence - light made by living organisms - on RNZ National's Our Changing World.

Visit the story on the RNZ website

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Genetics of truffle-like fungi

Picture of six specimens of purple pouch fungus.

Some fungi, like mushrooms, have umbrella-like caps, others, like truffles, have a lumpy potato-like appearance. Still others resemble truffles, but strangely are more closely related to mushrooms than truffles. Dr Chris Brown, along with collaborators in the Botany Department, are sequencing the DNA from truffle-like and pouch fungi to find out how they have evolved. They talk to RNZ National's Our Changing World about their research.

Visit the story on the RNZ website

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Battling breast cancer at the molecular level

Breast cancer cells as viewed through a microscope.

Dr Anita Dunbier’s research into breast cancer has shown that immune cells can play a `Jekyll and Hyde' role, either attacking and destroying a tumour or helping it to grow.

Visit the story on the Otago Daily Times website


Lipoprotein little a … a high risk for heart disease

Micrograph of a cell that has ‘swallowed’ lipoprotein(a) particles.

Research into lipoproteins, molecules that carry fats and cholesterol in the blood, is showing us new ways to develop drugs to treat heart disease. Professor Sally McCormick tells us more about a type of lipoprotein that she has been studying in detail.

Visit the story on the RNZ website

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Harnessing photosynthesis for energy production

Tim Crawford describing his PhD thesis research in three minutes.Tim Crawford, a former PhD student in Professor Julian Eaton-Rye’s research group, made the finals of the 2012 University of Otago three minute thesis competition. He talks about his research into some of the molecules that are involved with photosynthesis, and how such research could eventually be used to harness photosynthesis for industrial energy production.