Waller, N. J. E., Cheung, C.-Y., Cook, G. M., & McNeil, M. B. (2023). The evolution of antibiotic resistance is associated with collateral drug phenotypes in Mycobacterium tuberculosis. Nature Communications, 14, 1517. doi: 10.1038/s41467-023-37184-7

Journal - Research Article

Adolph, C., McNeil, M. B., & Cook, G. M. (2022). Impaired succinate oxidation prevents growth and influences drug susceptibility in Mycobacterium tuberculosis. mBio. Advance online publication. doi: 10.1128/mbio.01672-22

Journal - Research Article

Cheung, C.-Y., McNeil, M. B., & Cook, G. M. (2022). Utilization of CRISPR interference to investigate the contribution of genes to pathogenesis in a macrophage model of Mycobacterium tuberculosis infection. Journal of Antimicrobial Chemotherapy, 77, 615-619. doi: 10.1093/jac/dkab437

Journal - Research Article

Hards, K., Cheung, C.-Y., Waller, N., Adolph, C., Keighley, L., Tee, Z. S., Harold, L. K., Menorca, A., … Tyndall, J. D. A., McNeil, M. B., … Opel-Reading, H. K., Krause, K. L., … Berney, M., … Cook, G. M. (2022). An amiloride derivative is active against the F₁F_o-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis. Communications Biology, 5, 166. doi: 10.1038/s42003-022-03110-8

Journal - Research Article

Harold, L. K., Jinich, A., Hards, K., Cordeiro, A., Keighley, L. M., Cross, A., McNeil, M. B., … Cook, G. M. (2022). Deciphering functional redundancy and energetics of malate oxidation in mycobacteria. Journal of Biological Chemistry. Advance online publication. doi: 10.1016/j.jbc.2022.101859

Journal - Research Article

McNeil, M. B., Ryburn, H. W., Tirados, J., Cheung, C.-Y., & Cook, G. M. (2022). Multiplexed transcriptional repression identifies a network of bactericidal interactions between mycobacterial respiratory complexes. iScience, 25(1), 103573. doi: 10.1016/j.isci.2021.103573

Journal - Research Article

McNeil, M. B., Keighley, L. M., Cook, J. R., Cheung, C.-Y., & Cook, G. M. (2021). CRISPR interference identifies vulnerable cellular pathways with bactericidal phenotypes in Mycobacterium tuberculosis. Molecular Microbiology, 116, 1033-1043. doi: 10.1111/mmi.14790

Journal - Research Article

Shelton, C. D., McNeil, M. B., Early, J. V., Ioerger, T. R., & Parish, T. (2021). Deletion of Rv2571c confers resistance to arylamide compounds in Mycobacterium tuberculosis. Antimicrobial Agents & Chemotherapy, 65, e02334-20. doi: 10.1128/aac.02334-20

Journal - Research Article

McNeil, M. B., O'Malley, T., Dennison, D., Shelton, C. D., Sunde, B., & Parish, T. (2020). Multiple mutations in Mycobacterium tuberculosis MmpL3 increase resistance to MmpL3 inhibitors. mSphere, 5(5), e00985-20. doi: 10.1128/mSphere.00985-20

Journal - Research Article

McNeil, M. B., Ryburn, H. W. K., Harold, L. K., Tirados, J. F., & Cook, G. M. (2020). Transcriptional inhibition of the F₁F₀-type ATP synthase has bactericidal consequences on the viability of mycobacteria. Antimicrobial Agents & Chemotherapy, 64(8), e00492-20. doi: 10.1128/aac.00492-20

Journal - Research Article

Shao, M., McNeil, M., Cook, G. M., & Lu, X. (2020). MmpL3 inhibitors as antituberculosis drugs. European Journal of Medicinal Chemistry, 200, 112390. doi: 10.1016/j.ejmech.2020.112390

Journal - Research Article

McNeil, M. B., Dennison, D. D., Shelton, C. D., & Parish, T. (2017). In vitro isolation and characterization of oxazolidinone-resistant Mycobacterium tuberculosis. Antimicrobial Agents & Chemotherapy, 61(10), e01296-17. doi: 10.1128/aac.01296-17

Journal - Research Article

McNeil, M. B., Dennison, D., Shelton, C., Flint, L., Korkegian, A., & Parish, T. (2017). Mechanisms of resistance against NITD-916, a direct inhibitor of Mycobacterium tuberculosis InhA. Tuberculosis, 107, 133-136. doi: 10.1016/j.tube.2017.09.003

Journal - Research Article

Hampton, H. G., McNeil, M. B., Paterson, T. J., Ney, B., Williamson, N. R., Easingwood, R. A., Bostina, M., … Fineran, P. C. (2016). CRISPR-Cas gene-editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia. Microbiology, 162(6), 1047-1058. doi: 10.1099/mic.0.000283

Journal - Research Article

McNeil, M. B., Hampton, H. G., Hards, K. J., Watson, B. N. J., Cook, G. M., & Fineran, P. C. (2014). The succinate dehydrogenase assembly factor, SdhE, is required for the flavinylation and activation of fumarate reductase in bacteria. FEBS Letters, 588(3), 414-421. doi: 10.1016/j.febslet.2013.12.019

Journal - Research Article

Richter, C., Dy, R. L., McKenzie, R. E., Watson, B. N. J., Taylor, C., Chang, J. T., McNeil, M. B., Staals, R. H. J., & Fineran, P. C. (2014). Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer. Nucleic Acids Research, 42(13), 8516-8526. doi: 10.1093/nar/gku527

Journal - Research Article

Fineran, P. C., Iglesias Cans, M. C., Ramsay, J. P., Wilf, N. M., Cossyleon, D., McNeil, M. B., … Stanton, J.-A. L., … Salmond, G. P. C. (2013). Draft genome sequence of Serratia sp. strain ATCC 39006, a model bacterium for analysis of the biosynthesis and regulation of prodigiosin, a carbapenem, and gas vesicles. Genome Announcements, 1(6), e01039-13. doi: 10.1128/genomeA.01039-13

Journal - Research Article

McNeil, M. B., & Fineran, P. C. (2013). Prokaryotic assembly factors for the attachment of flavin to complex II. Biochimica et Biophysica Acta: Bioenergetics, 1827, 637-647. doi: 10.1016/j.bbabio.2012.09.003

Journal - Research Article

McNeil, M. B., & Fineran, P. C. (2013). The conserved RGxxE motif of the bacterial FAD assembly factor SdhE is required for succinate dehydrogenase flavinylation and activity. Biochemistry, 52, 7628-7640. doi: 10.1021/bi401006a

Journal - Research Article

McNeil, M. B., Iglesias Cans, M. C., Clulow, J. S., & Fineran, P. C. (2013). YgfX (CptA) is a multimeric membrane protein that interacts with the succinate dehydrogenase assembly factor SdhE (YgfY). Microbiology, 159, 1352-1365. doi: 10.1099/mic.0.068510-0

Journal - Research Article

McNeil, M. B., Clulow, J. S., Wilf, N. M., Salmond, G. P. C., & Fineran, P. C. (2012). SdhE is a conserved protein required for the flavinylation of succinate dehydrogenase in bacteria. Journal of Biological Chemistry, 287(22), 18418-18428. doi: 10.1074/jbc.M111.293803

Journal - Research Article

Gristwood, T., McNeil, M. B., Clulow, J. S., Salmond, G. P. C., & Fineran, P. C. (2011). PigS and PigP regulate prodigiosin biosynthesis in Serratia via differential control of divergent operons, which include predicted transporters of sulfur-containing molecules. Journal of Bacteriology, 193(5), 1076-1085. doi: 10.1128/JB.00352-10

Journal - Research Article

McNeil, M. B., Cheung, C.-Y., Waller, N. J. E., Adolph, C., Chapman, C. L., Seeto, N. E. J., Jowsey, W., … Cook, G. M. (2022). Uncovering interactions between mycobacterial respiratory complexes to target drug-resistant Mycobacterium tuberculosis. Frontiers in Cellular & Infection Microbiology, 12, 980844. doi: 10.3389/fcimb.2022.980844

Journal - Research Other

Hards, K., Adolph, C., Harold, L. K., McNeil, M. B., Cheung, C.-Y., Jinich, A., … Cook, G. M. (2020). Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents. Progress in Biophysics & Molecular Biology, 152, 35-44. doi: 10.1016/j.pbiomolbio.2019.11.003

Journal - Research Other

McNeil, M. B., & Cook, G. M. (2019). Utilization of CRISPR interference to validate MmpL3 as a drug target in Mycobacterium tuberculosis. Antimicrobial Agents & Chemotherapy, 63(8), e00629-19. doi: 10.1128/aac.00629-19

Journal - Research Other

McNeil, M. B., Dennison, D., & Parish, T. (2017). Mutations in MmpL3 alter membrane potential, hydrophobicity and antibiotic susceptibility in Mycobacterium smegmatis [Short communication]. Microbiology, 163(7), 1065-1070. doi: 10.1099/mic.0.000498

Journal - Research Other