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Dr Aline Boer

PositionResearch Fellow
Research summaryResearch into the central role of glucose-dependent insulinotropic polypeptide (GIP) in the regulation of body weight
MembershipsPublicity and Events Committee

Publications

Boer, G. A., Hay, D. L., & Tups, A. (2022). Obesity pharmacotherapy: Incretin action in the central nervous system [Review]. Trends in Pharmacological Sciences, 44(1), 50-63. doi: 10.1016/j.tips.2022.11.001

Gabe, M. B. N., Skov-Jeppesen, K., Gasbjerg, L. S., Schiellerup, S. P., Martinussen, C., Gadgaard, S., Boer, G. A., … Rosenkilde, M. M. (2022). GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment. Pharmacological Research, 176, 106058. doi: 10.1016/j.phrs.2022.106058

Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Hunt, J. E., Gabe, M. B. N., Windeløv, J. A., Boer, G. A., … Rosenkilde, M. M. (2022). Novel agonist- and antagonist-based radioligands for the GLP-2 receptor: Useful tools for studies of basic GLP-2R pharmacology. British Journal of Pharmacology, 179, 1998-2015. doi: 10.1111/bph.15766

Boer, G. A., Hartmann, B., & Holst, J. J. (2021). Pharmacokinetics of exogenous GIP(1-42) in C57Bl/6 mice: Extremely rapid degradation but marked variation between available assays. Peptides, 136, 170457. doi: 10.1016/j.peptides.2020.170457

Boer, G. A., Keenan, S. N., Miotto, P. M., Holst, J. J., & Watt, M. J. (2021). GIP receptor deletion in mice confers resistance to high-fat diet-induced obesity via alterations in energy expenditure and adipose tissue lipid metabolism. American Journal of Physiology: Heart & Circulatory Physiology, 320(4), E835-E845. doi: 10.1152/AJPENDO.00646.2020

Boer, G. A., Hay, D. L., & Tups, A. (2022). Obesity pharmacotherapy: Incretin action in the central nervous system [Review]. Trends in Pharmacological Sciences, 44(1), 50-63. doi: 10.1016/j.tips.2022.11.001

Journal - Research Article

Gabe, M. B. N., Skov-Jeppesen, K., Gasbjerg, L. S., Schiellerup, S. P., Martinussen, C., Gadgaard, S., Boer, G. A., … Rosenkilde, M. M. (2022). GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment. Pharmacological Research, 176, 106058. doi: 10.1016/j.phrs.2022.106058

Journal - Research Article

Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Hunt, J. E., Gabe, M. B. N., Windeløv, J. A., Boer, G. A., … Rosenkilde, M. M. (2022). Novel agonist- and antagonist-based radioligands for the GLP-2 receptor: Useful tools for studies of basic GLP-2R pharmacology. British Journal of Pharmacology, 179, 1998-2015. doi: 10.1111/bph.15766

Journal - Research Article

Boer, G. A., Hartmann, B., & Holst, J. J. (2021). Pharmacokinetics of exogenous GIP(1-42) in C57Bl/6 mice: Extremely rapid degradation but marked variation between available assays. Peptides, 136, 170457. doi: 10.1016/j.peptides.2020.170457

Journal - Research Article

Boer, G. A., Keenan, S. N., Miotto, P. M., Holst, J. J., & Watt, M. J. (2021). GIP receptor deletion in mice confers resistance to high-fat diet-induced obesity via alterations in energy expenditure and adipose tissue lipid metabolism. American Journal of Physiology: Heart & Circulatory Physiology, 320(4), E835-E845. doi: 10.1152/AJPENDO.00646.2020

Journal - Research Article

Lubberding, A. F., Zhang, J., Lundh, M., Nielsen, T. S., Søndergaard, M. S., Villadsen, M., … Boer, G. A., … Torekov, S. S. (2021). Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V. Scientific Reports, 11(1), 12253. doi: 10.1038/s41598-021-90452-8

Journal - Research Article

Boer, G. A., & Holst, J. J. (2020). Incretin hormones and type 2 diabetes: Mechanistic insights and therapeutic approaches. Biology, 9(12), 473. doi: 10.3390/biology9120473

Journal - Research Article

Gobron, B., Bouvard, B., Vyavahare, S., Blom, L. V. V., Pedersen, K. K., Windeløv, J. A., Boer, G. A., … Mabilleau, G. (2020). Enteroendocrine K cells exert complementary effects to control bone quality and mass in mice. Journal of Bone & Mineral Research, 35(7), 1363-1374. doi: 10.1002/jbmr.4004

Journal - Research Article

Holst, J. J., Windeløv, J. A., Boer, G. A., Pedersen, J., Svendsen, B., Christensen, M., … Nissen, A. (2016). Searching for the physiological role of glucose-dependent insulinotropic polypeptide. Journal of Diabetes Investigation, 7(Suppl. 1), 8-12. doi: 10.1111/jdi.12488

Journal - Research Other

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