School of Biomedical Sciences

Donovan, K. A., Beaglehole, B., Frampton, C. M. A., Currie, M., Boden, J. M., & Jordan, J. (2023). Tōku Oranga: The subjective wellbeing and psychological functioning of postgraduate and medical students in Ōtautahi Christchurch. New Zealand Medical Journal/Te ara tika o te hauora hapori, 136(1586), 51-62. Retrieved from https://journal.nzma.org.nz/

Journal - Research Article

Symonds, E. K. C., Black, B., Brown, A., Meredith, I., Currie, M. J., Hally, K. E., & Danielson, K. M. (2023). Adipose derived stem cell extracellular vesicles modulate primary human macrophages to an anti-inflammatory phenotype in vitro. Journal of Extracellular Biology, 2, e104. doi: 10.1002/jex2.104

Journal - Research Article

Rajesh, A., Saito, M., Morrin, H., Tschirley, A., Simcock, J., Currie, M., & Hibma, M. (2022). Characterisation of the immune microenvironment of cutaneous squamous cell carcinoma in immunosuppression. Experimental Dermatology, 31, 1720-1728. doi: 10.1111/exd.14650

Journal - Research Article

Ang, A. D., Vissers, M. C. M., Burgess, E. R., Currie, M. J., & Dachs, G. U. (2021). Gene and protein expression is altered by ascorbate availability in murine macrophages cultured under tumour-like conditions. Antioxidants, 10(3), 430. doi: 10.3390/antiox10030430

Journal - Research Article

Buss, L. A., Hock, B., Merry, T. L., Ang, A. D., Robinson, B. A., Currie, M. J., & Dachs, G. U. (2021). Effect of immune modulation on the skeletal muscle mitochondrial exercise response: An exploratory study in mice with cancer. PLoS ONE, 16(10), e0258831. doi: 10.1371/journal.pone.0258831

Journal - Research Article

Buss, L. A., Williams, T., Hock, B., Ang, A. D., Robinson, B. A., Currie, M. J., & Dachs, G. U. (2021). Effects of exercise and anti-PD-1 on the tumour microenvironment. Immunology Letters, 239, 60-71. doi: 10.1016/j.imlet.2021.08.005

Journal - Research Article

Crake, R. L. I., Strother, M. R., Phillips, E., Doogue, M. P., Zhang, M., Frampton, C. M. A., Robinson, B. A., & Currie, M. J. (2021). Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: A patient feasibility study. Scientific Reports, 11(1), 5648. doi: 10.1038/s41598-021-85048-1

Journal - Research Article

Morley-Bunker, A. E., Wiggins, G. A. R., Currie, M. J., Morrin, H. R., Whitehead, M. R., Eglinton, T., Pearson, J., & Walker, L. C. (2021). RNAscope compatibility with image analysis platforms for the quantification of tissue-based colorectal cancer biomarkers in archival formalin-fixed paraffin-embedded tissue. Acta Histochemica, 123, 151765. doi: 10.1016/j.acthis.2021.151765

Journal - Research Article

Stamp, L. K., Cameron, V. A., Woodfield, T. B. F., Walker, L., Currie, M., Templeton, E., Pilbrow, A. P., Tabakakis, K., Phillips, E., & Lim, K. S. (2021). Impact of COVID-19 on health research in New Zealand: A case study of a research-intensive campus. Journal of the Royal Society of New Zealand, 51(Suppl. 1), S75-S85. doi: 10.1080/03036758.2020.1867202

Journal - Research Article

Buss, L. A., Ang, A. D., Hock, B., Robinson, B. A., Currie, M. J., & Dachs, G. U. (2020). Effect of post-implant exercise on tumour growth rate, perfusion and hypoxia in mice. PLoS ONE, 15(3), e0229290. doi: 10.1371/journal.pone.0229290

Journal - Research Article

Hock, B. D., McKenzie, J. L., Strother, M., Goddard, L., Butt, L., & Currie, M. J. (2020). Functional effects of immune complexes formed between pembrolizumab and patient-generated anti-drug antibodies. Cancer Immunology, Immunotherapy, 69(12), 2453-2464. doi: 10.1007/s00262-020-02636-2

Journal - Research Article

Richardson, A. K., Walker, L. C., Cox, B., Rollag, H., Robinson, B. A., Morrin, H., Pearson, J. F., … Currie, M. J. (2020). Breast cancer and cytomegalovirus. Clinical & Translational Oncology, 22, 585-602. doi: 10.1007/s12094-019-02164-1

Journal - Research Article

Crake, R. L. I., Phillips, E., Kleffmann, T., & Currie, M. J. (2019). Co-culture with human breast adipocytes differentially regulates protein abundance in breast cancer cells. Cancer Geonomics & Proteomics, 16(5), 319-332. doi: 10.21873/cgp.20137

Journal - Research Article

Lattimore, V. L., Pearson, J. F., Morley-Bunker, A. E., kConFab Investigators, Spurdle, A. B., Robinson, B. A., Currie, M. J., & Walker, L. C. (2019). Quantifying BRCA1 and BRCA2 mRNA isoform expression levels in single cells. International Journal of Molecular Sciences, 20(3), 693. doi: 10.3390/ijms20030693

Journal - Research Article

Morley-Bunker, A., Pearson, J., Currie, M. J., Morrin, H., Whitehead, M. R., Eglinton, T., & Walker, L. C. (2019). Assessment of intra-tumoural colorectal cancer prognostic biomarkers using RNA in situ hybridisation. Oncotarget, 10(14), 1425-1439. doi: 10.18632/oncotarget.26675

Journal - Research Article

Buss, L. A., Mandani, A., Phillips, E., Scott, N. J. A., Currie, M. J., & Dachs, G. U. (2018). Characterisation of a mouse model of breast cancer with metabolic syndrome. In Vivo, 32(5), 1071-1080. doi: 10.21873/invivo.11348

Journal - Research Article

Lattimore, V. L., Pearson, J. F., Currie, M. J., Spurdle, A. B., kConFab Investigators, Robinson, B. A., & Walker, L. C. (2018). Investigation of experimental factors that underlie BRCA1/2 mRNA isoform expression variation: Recommendations for utilising targeted RNA sequencing to evaluate potential spliceogenic variants. Frontiers in Oncology, 8, 140. doi: 10.3389/fonc.2018.00140

Journal - Research Article

Robinson, B., Currie, M., Phillips, E., Dachs, G., Strother, M., Morrin, H., Davey, V., & Frampton, C. (2017). Body mass index (BMI): Association with clinicopathological factors and outcome of women with newly diagnosed breast cancer in New Zealand. New Zealand Medical Journal, 130(1451), 46-56. Retrieved from https://www.nzma.org.nz/journal

Journal - Research Article

Morley-Bunker, A., Walker, L. C., Currie, M. J., Pearson, J., & Eglinton, T. (2016). Translating colorectal cancer genetics into clinically useful biomarkers. Colorectal Disease, 18(8), 749-762. doi: 10.1111/codi.13334

Journal - Research Article

Royds, J. A., Pilbrow, A. P., Morrin, H. R., Frampton, C., Russell, I. A., Moravec, C. S., … Currie, M. J., Hung, N. A., & Slatter, T. L. (2016). The rs11515 polymorphism is more frequent and associated with aggressive breast tumors with increased ANRIL and decreased p16^INK4a expression. Frontiers in Oncology, 5, 306. doi: 10.3389/fonc.2015.00306

Journal - Research Article

Seddon, A., Hock, B., Miller, A., Frei, L., Pearson, J., McKenzie, J., Simcock, J., & Currie, M. (2016). Cutaneous squamous cell carcinomas with markers of increased metastatic risk are associated with elevated numbers of neutrophils and/or granulocytic myeloid derived suppressor cells. Journal of Dermatological Science, 83(2), 124-130. doi: 10.1016/j.jdermsci.2016.04.013

Journal - Research Article

Dachs, G. U., Phillips, E., Phung, Y., Dyer, A., Willis, J. A., Currie, M. J., & Robinson, B. A. (2015). Tumour growth in mice resistant to diet-induced obesity. Journal of Molecular Biochemistry, 4(2), 42-49.

Journal - Research Article

Hock, B. D., McKenzie, J. L., Cross, N. B., & Currie, M. J. (2015). Dynamic changes in myeloid derived suppressor cell subsets following renal transplant: A prospective study. Transplant Immunology, 32(3), 164-171. doi: 10.1016/j.trim.2015.05.001

Journal - Research Article

Richardson, A. K., Currie, M. J., Robinson, B. A., Morrin, H., Phung, Y., Pearson, J. F., … Walker, L. C. (2015). Cytomegalovirus and Epstein-Barr Virus in breast cancer. PLoS ONE, 10(2), e0118989. doi: 10.1371/journal.pone.0118989

Journal - Research Article

Kuiper, C., Dachs, G. U., Currie, M. J., & Vissers, M. C. M. (2014). Intracellular ascorbate enhances hypoxia-inducible factor (HIF)-hydroxylase activity and preferentially suppresses the HIF-1 transcriptional response. Free Radical Biology & Medicine, 69, 308-317. doi: 10.1016/j.freeradbiomed.2014.01.033

Journal - Research Article

Kuiper, C., Dachs, G. U., Munn, D., Currie, M. J., Robinson, B. A., Pearson, J. F., & Vissers, M. C. M. (2014). Increased tumour ascorbate is associated with extended disease-free survival and decreased hypoxia-inducible factor-1 activation in human colorectal cancer. Frontiers in Oncology, 4, 10. doi: 10.3389/fonc.2014.00010

Journal - Research Article

Volkova, E., Robinson, B. A., Willis, J., Currie, M. J., & Dachs, G. U. (2014). Marginal effects of glucose, insulin and insulin-like growth factor on chemotherapy response in endothelial and colorectal cancer cells. Oncology Letters, 7(2), 311-320. doi: 10.3892/ol.2013.1710

Journal - Research Article

Currie, M. J., Beardsley, B. E., Harris, G. C., Gunningham, S. P., Dachs, G. U., Dijkstra, B., Morrin, H. R., Wells, J. E., & Robinson, B. A. (2013). Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal carcinoma in situ: Relationships with markers of tumor hypoxia and microvascularity. Human Pathology, 44(3), 402-411. doi: 10.1016/j.humpath.2012.06.004

Journal - Research Article

Hock, B. D., Mackenzie, K. A., Cross, N. B., Taylor, K. G., Currie, M. J., Robinson, B. A., Simcock, J. W., & McKenzie, J. L. (2012). Renal transplant recipients have elevated frequencies of circulating myeloid-derived suppressor cells. Nephrology Dialysis Transplantation, 27(1), 402-410. doi: 10.1093/ndt/gfr264

Journal - Research Article

Hunt, M. A., Li, D., Hay, M. P., Currie, M. J., Robinson, B. A., Patterson, A. V., & Dachs, G. U. (2012). Characterisation of enzyme prodrug gene therapy combinations in coated spheroids and vascular networks in vitro. Journal of Gene Medicine, 14(1), 62-74. doi: 10.1002/jgm.1635

Journal - Research Article

MacKenzie, K. A., Miller, A. P., Hock, B. D., Gardner, J., Simcock, J. W., Roake, J. A., Dachs, G. U., Robinson, B. A., & Currie, M. J. (2011). Angiogenesis and host immune response contribute to the aggressive character of non-melanoma skin cancers in renal transplant recipients. Histopathology, 58(6), 875-885. doi: 10.1111/j.1365-2559.2011.03845.x

Journal - Research Article

Pflüger, H.-J., Field, L. H., Nishino, H., & Currie, M. J. (2011). Neuromodulatory unpaired median neurons in the New Zealand tree weta, Hemideina femorata. Journal of Insect Physiology, 57(10), 1420-1430. doi: 10.1016/j.jinsphys.2011.07.010

Journal - Research Article

Volkova, E., Willis, J. A., Wells, J. E., Robinson, B. A., Dachs, G. U., & Currie, M. J. (2011). Association of angiopoietin-2, C-reactive protein and markers of obesity and insulin resistance with survival outcome in colorectal cancer. British Journal of Cancer, 104, 51-59. doi: 10.1038/sj.bjc.6606005

Journal - Research Article

Dachs, G. U., Kano, M., Volkova, E., Morrin, H. R., Davey, V. C. L., Harris, G. C., … Frampton, C., Currie, M. J., Wells, J. E., & Robinson, B. A. (2010). A profile of prognostic and molecular factors in European and Māori breast cancer patients. BMC Cancer, 10, 543. doi: 10.1186/1471-2407-10-543

Journal - Research Article

Hunt, M. A., Currie, M. J., Robinson, B. A., & Dachs, G. U. (2010). Optimizing transfection of primary human umbilical vein endothelial cells using commercially available chemical transfection reagents. Journal of Biomolecular Techniques, 21, 66-72.

Journal - Research Article

Kuiper, C., Molenaar, I. G. M., Dachs, G. U., Currie, M. J., Sykes, P. H., & Vissers, M. C. M. (2010). Low ascorbate levels are associated with increased hypoxia-inducible factor-1 activity and an aggressive tumor phenotype in endometrial cancer. Cancer Research, 70(14), 5749-5758. doi: 10.1158/0008-5472.CAN-10-0263

Journal - Research Article

Mackenzie, K. A., Wells, J. E., Lynn, K. L., Simcock, J. W., Robinson, B. A., Roake, J. A., & Currie, M. J. (2010). First and subsequent nonmelanoma skin cancers: Incidence and predictors in a population of New Zealand renal transplant recipients. Nephrology Dialysis Transplantation, 25, 300-306. doi: 10.1093/ndt/gfp482

Journal - Research Article

Dachs, G. U., Currie, M. J., Mckenzie, F., Jeffreys, M., Cox, B., Foliaki, S., … Robinson, B. A. (2008). Cancer disparities in indigenous Polynesian populations: Māori, Native Hawaiians, and Pacific people. Lancet Oncology, 9(5), 473-484. doi: 10.1016/S1470-2045(08)70127-X

Journal - Research Article

Gunningham, S. P., Currie, M. J., Morrin, H. R., Tan, E. Y., Turley, H., Dachs, G. U., Watson, A. I., Frampton, C., Robinson, B. A., & Fox, S. B. (2007). The angiogenic factor thymidine phosphorylase up-regulates the cell adhesion molecule P-selectin in human vascular endothelial cells and is asociated with P-selectin expression in breast cancers. Journal of Pathology, 212, 335-344.

Journal - Research Article

Vissers, M. C. M., Gunningham, S. P., Morrison, M. J., Dachs, G. U., & Currie, M. J. (2007). Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate. Free Radical Biology & Medicine, 42, 765-772.

Journal - Research Article

Dachs, G. U., Steele, A. J., Coralli, C., Kanthou, C., Brooks, A. C., Gunningham, S. P., Currie, M. J., Watson, A. I., Robinson, B. A., & Tozer, G. M. (2006). Anti-vascular agent Combretastatin A-4-P modulates hypoxia inducible factor-I and gene expression. BMC Cancer, 6, 280. doi: 10.1186/1471-2407-6-280

Journal - Research Article

Jarvis, M. D., Rademaker, M. T., Ellmers, L. J., Currie, M. J., McKenzie, J. L., Palmer, B. R., Frampton, C. M., Richards, A. M., & Cameron, V. A. (2006). Comparison of infarct-derived and control ovine cardiac myofibroblasts in culture: Response to cytokines and natriuretic peptide receptor expression profiles. American Journal of Physiology: Heart & Circulatory Physiology, 291, H1952-H1958. doi: 10.1152/ajpheart.00764.2005

Journal - Research Article

Currie, M. J., Hanrahan, V., Gunningham, S. P., Morrin, H. R., Frampton, C., Han, C., Robinson, B. A., & Fox, S. B. (2005). Expression of HIF-1α in human tumours. Journal of Clinical Pathology, 58, 335-336.

Journal - Research Article

Morrin, H., Gunningham, S., Currie, M., Dachs, G., Fox, S., & Robinson, B. (2005). The Christchurch Tissue Bank to support cancer research. New Zealand Medical Journal, 118(1225). Retrieved from http://journal.nzma.org.nz/journal/118-1225/1735/content.pdf

Journal - Research Article

Currie, M., Hanrahan, V., Gunningham, S. P., Morrin, H. R., Frampton, C., Han, C., Robinson, B. A., & Fox, S. B. (2004). Expression of vascular endothelial growth factor D is associated with hypoxia inducible factor (HIF-1α) and the HIF-1α target gene DEC1, but not lymph node metastasis in primary human breast carcinomas. Journal of Clinical Pathology, 57, 829-834.

Journal - Research Article

Hanrahan, V., Currie, M., Gunningham, S. P., Morrin, H., Scott, P. A. E., Robinson, B. A., & Fox, S. B. (2003). The angiogenic switch for vascular endothelial growth factor (VEGF)-A, VEGF-B, VEGF-C, and VEGF-D in the adenoma-carcinoma sequence during colorectal cancer progression. Journal of Pathology, 200(2), 183-194.

Journal - Research Article

Currie, M., Gunningham, S. P., Cheng, H., Robinson, B. A., Scott, P. A. E., Harris, A. L., & Fox, S. B. (2002). Expression of the angiopoietins and their receptor Tie2 in human renal clear cell carcinomas; Regulation by the von Hippel-Lindau gene and hypoxia. Journal of Pathology, 198, 502-510.

Journal - Research Article

Currie, M., Gunningham, S. P., Han, C., Scott, P. A. E., Robinson, B. A., Harris, A., & Fox, S. B. (2001). Angiopoietin-1 is inversely related to thymidine phosphorylase expression in human breast cancer, indicating a role in vascular remodeling. Clinical Cancer Research, 7(4), 918-927.

Journal - Research Article

Gunningham, S. P., Currie, M. J., Han, C., Robinson, B. A., Scott, P. A. E., Harris, A. L., & Fox, S. B. (2001). VEGF-B expression in human primary breast cancers is associated with lymph node metastasis but not angiogenesis. Journal of Pathology, 193(3), 325-332.

Journal - Research Article

Gunningham, S. P., Currie, M. J., Han, C., Turner, K. S., Scott, P. A. E., Robinson, B. A., … Fox, S. B. (2001). Vascular endothelial growth factor-B and vascular endothelial growth factor-C expression in renal cell carcinomas: Regulation by the von Hippel-Lindau gene and hypoxia. Cancer Research, 61(7), 3206-3211.

Journal - Research Article

Gunningham, S. P., Currie, M. J., Han, C., Robinson, B. A., Scott, P. A. E., Harris, A. L., & Fox, S. B. (2000). The short form of the alternatively spliced flt-4 but not its ligand vascular endothelial growth factor C is related to lymph node metastasis in human breast cancers. Clinical Cancer Research, 6(11), 4278-4286.

Journal - Research Article

Bassett, N. S., Currie, M., Breier, B. H., Klempt, M., Min, S. H., McCutcheon, S. N., … Gluckman, P. (1997). The effects of ovine placental bitogen and bovine growth hormone on hepatic and mammary gene expression in lactating sheep. Growth Hormone & IGF Research, 8(6), 439-446.

Journal - Research Article

Currie, M. J., Bassett, N. S., & Gluckman, P. D. (1997). Ovine glucose transporter - 1 and 3: DNA partial sequences and development gene expression in the placenta. Placenta, 18, 393-401.

Journal - Research Article

Currie, M., Bassett, N. S., & Gluckman, P. (1997). Ovine glucose transporter - 1 and 3: DNA partial sequences and development gene expression in the placenta. Placenta, 18, 393-491.

Journal - Research Article

Yunianto, I., Currie, M., Chitcholtan, K., & Sykes, P. (2023). Potential drug repurposing of ruxolitinib to inhibit the JAK/STAT pathway for the treatment of patients with epithelial ovarian cancer. Journal of Obstetrics & Gynaecology Research, 49, 2563-2574. doi: 10.1111/jog.15761

Journal - Research Other

Allan, J., Buss, L. A., Draper, N., & Currie, M. J. (2022). Exercise in people with cancer: A spotlight on energy regulation and cachexia. Frontiers in Physiology, 13, 836804. doi: 10.3389/fphys.2022.836804

Journal - Research Other

van der Woude, H., Hally, K. E., Currie, M. J., Gasser, O., & Henry, C. E. (2022). Importance of the endometrial immune environment in endometrial cancer and associated therapies. Frontiers in Oncology, 12, 975201. doi: 10.3389/fonc.2022.975201

Journal - Research Other

Buss, L. A., Dachs, G. U., Goddard, L., Ang, A. D., Robinson, B. A., Currie, M. J., & Hock, B. (2021). Is the immunogenicity of PD-1 blocking antibodies a confounding variable in murine studies? Immunology Letters, 234, 13-15. doi: 10.1016/j.imlet.2021.04.003

Journal - Research Other

Ang, A., Pullar, J. M., Currie, M. J., & Vissers, M. C. M. (2018). Vitamin C and immune cell function in inflammation and cancer. Biochemical Society Transactions, 46, 1147-1159. doi: 10.1042/bst20180169

Journal - Research Other

Lattimore, V., Currie, M., Lintott, C., Sullivan, J., Robinson, B. A., & Walker, L. C. (2015). Meeting the challenges of interpreting variants of unknown clinical significance in BRCA testing. New Zealand Medical Journal, 128(1419). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Other

Mackenzie, K. A., Simcock, J. W., Lainchbury, J. G., Currie, M. J., & Lynn, K. L. (2009). Myocardial metastasis of cutaneous squamous cell carcinoma in a renal transplant recipient [Case report]. Transplantation Proceedings, 41(10), 4414-4415. doi: 10.1016/j.transproceed.2009.09.056

Journal - Research Other