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Linda Buss 2021 imagePostdoctoral Fellow

Email linda.buss@otago.ac.nz

Research interests

Dr Buss is currently establishing a method to grow heart muscle cells in the lab. This method will be used as a platform to investigate future research questions, including validating potential biomarkers of mild/moderate cardiac ischaemia that have been previously identified by our group.

Dr Buss is also interested in the intersection of the fields of heart disease and cancer (cardio-oncology), and aims to identify strategies to mitigate the adverse effects of cancer drugs on cardiovascular health.

Background

Dr Buss completed her PhD in the Department of Pathology and Biomedical Science at the University of Otago, Christchurch. Her PhD work focussed on how immunotherapy drugs modify the effect of exercise on cancer, and she joined the Christchurch Heart Institute in 2021, after completing her doctoral studies.

Publications

Allan, J., Buss, L. A., Draper, N., & Currie, M. J. (2022). Exercise in people with cancer: A spotlight on energy regulation and cachexia. Frontiers in Physiology, 13, 836804. doi: 10.3389/fphys.2022.836804 Journal - Research Other

Buss, L. A., Hock, B., Merry, T. L., Ang, A. D., Robinson, B. A., Currie, M. J., & Dachs, G. U. (2021). Effect of immune modulation on the skeletal muscle mitochondrial exercise response: An exploratory study in mice with cancer. PLoS ONE, 16(10), e0258831. doi: 10.1371/journal.pone.0258831 Journal - Research Article

Buss, L. A., Williams, T., Hock, B., Ang, A. D., Robinson, B. A., Currie, M. J., & Dachs, G. U. (2021). Effects of exercise and anti-PD-1 on the tumour microenvironment. Immunology Letters, 239, 60-71. doi: 10.1016/j.imlet.2021.08.005 Journal - Research Article

Buss, L. A., Dachs, G. U., Goddard, L., Ang, A. D., Robinson, B. A., Currie, M. J., & Hock, B. (2021). Is the immunogenicity of PD-1 blocking antibodies a confounding variable in murine studies? Immunology Letters, 234, 13-15. doi: 10.1016/j.imlet.2021.04.003 Journal - Research Other

Buss, L. A. (2020). The immune system: A common link mediating exercise effects on the tumour microenvironment and skeletal muscle mitochondria? (PhD). University of Otago, Dunedin, New Zealand. Retrieved from http://hdl.handle.net/10523/10530 Awarded Doctoral Degree

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