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Dr Carla Meledandri

carla_meledandriPhD(Dub), BSc(Penn State)

Tel: 03 479 5378
Location: Science II, 5c2
Email: cmeledandri@chemistry.otago.ac.nz

Research Interests

Our research is directed toward the design, synthesis, and characterization of functional nanoscale materials. The interest in nanoscale materials lies in the fact that their size, shape, and composition can dramatically affect their physical and chemical properties. This phenomenon can be exploited in order to develop new materials with tunable properties for a broad range of applications. Our interests encompass both fundamental and applied aspects of nanomaterials research. Current projects are interdisciplinary, combining chemistry, materials science, physics, and biological sciences in order to develop new materials with potential application in biomedicine and for use as nanoswitches.

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Publications

Feltham, H. L. C., Dankhoff, K., Meledandri, C. J., & Brooker, S. (2018). Towards dual-functionality spin-crossover complexes. ChemPlusChem, 83(7), 582-589. doi: 10.1002/cplu.201700512

Feltham, H. L. C., Dumas, C., Mannini, M., Otero, E., Sainctavit, P., Sessoli, R., Meledandri, C. J., & Brooker, S. (2017). Proof of principle: Immobilisation of robust CuII3TbIII-macrocycles on small, suitably pre-functionalised gold nanoparticles. Chemistry: A European Journal, 23(11), 2517-2521. doi: 10.1002/chem.201604821

Rodpun, K., Lucas, N. T., Tan, E. W., & Meledandri, C. J. (2016). Development of solvent-dispersible coordination polymer nanocrystals and application as efficient heterogeneous catalysts. Crystal Growth & Design, 16(7), 3940-3946. doi: 10.1021/acs.cgd.6b00502

Stolarczyk, J. K., Meledandri, C. J., Clarke, S. P., & Brougham, D. F. (2016). Size selectable nanoparticle assemblies with magnetic anisotropy tunable across the superparamagnetic to ferromagnetic range. Chemical Communications, 52(91), 13337-13340. doi: 10.1039/c6cc05871j

Dumas, C., & Meledandri, C. J. (2015). Insights into the partitioning behavior of secondary surfactants in a microemulsion-based synthesis of metal nanoparticles: A DLS and 2D NMR spectroscopic investigation. Langmuir, 31(26), 7193-7203. doi: 10.1021/acs.langmuir.5b00417

Intellectual Property

Brougham, D., Meledandri, C., Stolarczyk, J., & Ninjbadgar, T. (2014). Nanoparticle clusters formed from individual nanoparticles of two or more types. (8,883,122). United States.

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Other Research Output

Meledandri, C. (2010, August). Membranes and membrane-bound magnetic nanoparticles with tunable properties for biomedical applications. University of Otago Department of Biochemistry Seminar, Dunedin, New Zealand. [Department Seminar].

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Journal - Research Article

Feltham, H. L. C., Dankhoff, K., Meledandri, C. J., & Brooker, S. (2018). Towards dual-functionality spin-crossover complexes. ChemPlusChem, 83(7), 582-589. doi: 10.1002/cplu.201700512

Feltham, H. L. C., Dumas, C., Mannini, M., Otero, E., Sainctavit, P., Sessoli, R., Meledandri, C. J., & Brooker, S. (2017). Proof of principle: Immobilisation of robust CuII3TbIII-macrocycles on small, suitably pre-functionalised gold nanoparticles. Chemistry: A European Journal, 23(11), 2517-2521. doi: 10.1002/chem.201604821

Rodpun, K., Lucas, N. T., Tan, E. W., & Meledandri, C. J. (2016). Development of solvent-dispersible coordination polymer nanocrystals and application as efficient heterogeneous catalysts. Crystal Growth & Design, 16(7), 3940-3946. doi: 10.1021/acs.cgd.6b00502

Rodpun, K., Blackman, A. G., Gardiner, M. G., Tan, E. W., Meledandri, C. J., & Lucas, N. T. (2015). Alkyl linker effects on the coordination topology of ditopic di(2-pyridylmethyl)amine carboxylate ligands with ZnII and CuII: Polymers vs. macrocycles. CrystEngComm, 17(15), 2974-2988. doi: 10.1039/c5ce00375j

Dumas, C., & Meledandri, C. J. (2015). Insights into the partitioning behavior of secondary surfactants in a microemulsion-based synthesis of metal nanoparticles: A DLS and 2D NMR spectroscopic investigation. Langmuir, 31(26), 7193-7203. doi: 10.1021/acs.langmuir.5b00417

Fraenza, C. C., Meledandri, C. J., Anoardo, E., & Brougham, D. F. (2014). The effect of cholesterol on membrane dynamics on different timescales in lipid bilayers from fast field-cycling NMR relaxometry studies of unilamellar vesicles. ChemPhysChem, 15(3), 425-435. doi: 10.1002/cphc.201301051

Garden, A. L., Scholz, K., Schwass, D. R., & Meledandri, C. J. (2014). Optimized colloidal chemistry for micelle-templated synthesis and assembly of silver nanocomposite materials. Colloids & Surfaces A, 441, 367-377. doi: 10.1016/j.colsurfa.2013.09.012

Garden, A. L., van der Salm, L., Schwass, D. R., & Meledandri, C. J. (2013). Towards a tunable microemulsion method for nanoparticle synthesis. RSC Advances, 3(7), 2192-2196. doi: 10.1039/C2RA21491A

Meledandri, C. J., & Brougham, D. F. (2012). Low field magnetic resonance techniques in the development of nanomaterials for biomedical applications. Analytical Methods, 4(2), 331-341. doi: 10.1039/c2ay05420e

Perlo, J., Meledandri, C. J., Anoardo, E., & Brougham, D. F. (2011). Temperature and size-dependence of membrane molecular dynamics in unilamellar vesicles by fast field-cycling NMR relaxometry. Journal of Physical Chemistry B, 115(13), 3444-3451. doi: 10.1021/jp2009034

Meledandri, C. J., Ninjbadgar, T., & Brougham, D. F. (2011). Size-controlled magnetoliposomes with tunable magnetic resonance relaxation enhancements. Journal of Materials Chemistry, 21, 214-222. doi: 10.1039/C0JM01061H

Meledandri, C. J., Stolarczyk, J. K., & Brougham, D. F. (2011). Hierarchical gold-decorated magnetic nanoparticle clusters with controlled size. ACS Nano, 5(3), 1747-1755. doi: 10.1021/nn102331c

Davies, G.-L., Corr, S. A., Meledandri, C. J., Briode, L., Brougham, D. F., & Gun'ko, Y. K. (2011). NMR relaxation of water in nanostructures: Analysis of ferromagnetic cobalt-ferrite polyelectrolyte nanocomposites. ChemPhysChem, 12(4), 772-776. doi: 10.1002/cphc.201000853

Meledandri, C. J., Perlo, J., Farrher, E., Brougham, D. F., & Anoardo, E. (2009). Interpretation of molecular dynamics on different time scales in unilamellar vesicles using field-cycling NMR relaxometry. Journal of Physical Chemistry B, 113, 15532-15540. doi: 10.1021/jp907084s

Corr, S. A., Byrne, S. J., Tekoriute, R., Meledandri, C. J., Brougham, D. F., Lynch, M., … Gun'ko, Y. K. (2008). Linear assemblies of magnetic nanoparticles as MRI contrast agents. Journal of the American Chemical Society, 130, 4214-4215. doi: 10.1021/ja710172z

Meledandri, C. J., Stolarczyk, J. K., Ghosh, S., & Brougham, D. F. (2008). Nonaqueous magnetic nanoparticle suspensions with controlled particle size and nuclear magnetic resonance properties. Langmuir, 24, 14159-14165. doi: 10.1021/la8018088

Corr, S. A., Gun'ko, Y. K., Tekoriute, R., Meledandri, C. J., & Brougham, D. F. (2008). Poly(sodium-4-styrene)sulfonate—iron oxide nanocomposite dispersions with controlled magnetic resonance properties. Journal of Physical Chemistry C, 112, 13324-13327. doi: 10.1021/jp805519n

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Journal - Research Other

Stolarczyk, J. K., Meledandri, C. J., Clarke, S. P., & Brougham, D. F. (2016). Size selectable nanoparticle assemblies with magnetic anisotropy tunable across the superparamagnetic to ferromagnetic range. Chemical Communications, 52(91), 13337-13340. doi: 10.1039/c6cc05871j

Schwass, D. R., & Meledandri, C. J. (2014). Enhanced penetration of silver nanocomposite assemblies into dentine using iontophoresis: Toward the treatment of dental caries [Communication]. ChemPlusChem, 79(12), 1671-1675. doi: 10.1002/cplu.201402132

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Conference Contribution - Published proceedings: Abstract

Cotton, G. C., Duncan, W. J., & Meledandri, C. J. (2017). An antimicrobial silver nanoparticle gel for treatment and prevention of dental disease: In vitro and in vivo results [Keynote speaker]. Proceedings of the 8th International Conference on Advanced Materials and Nanotechnology (AMN8). (pp. 47). Retrieved from http://confer.co.nz/amn8/

Kerr, D. S., Parker, S., Cotton, G., Meledandri, C., Falconer, J., & Grainger, D. W. (2016). Electrophysiological assessment of silver nanoparticle toxicity in an in vitro rat hippocampal slice preparation. In B. Leitch (Ed.), Proceedings of the 34th International Australasian Winter Conference on Brain Research. (pp. 29). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr

Cotton, G. C., Schwass, D. R., Duncan, W. J., Tompkins, G. R., & Meledandri, C. J. (2016). Synthesis of an antimicrobial mucoadhesive silver nanoparticle hydrogel for periodontal treatment. Proceedings of the Diagnostics, Drugs, Devices, Discovery (D4) Conference. Retrieved from http://www.otago.ac.nz/d4/index.html

Cotton, G. C., Meledandri, C. J., Schwass, D. R., & Tompkins, G. (2015). Topical antibacterial gel for treatment of periodontal disease. Dental Materials, 31(Suppl. 1), (pp. e39). doi: 10.1016/j.dental.2015.08.087

Schwass, D., & Meledandri, C. (2014). Enhanced antimicrobial activity and penetration of micelle-stabilised silver nanoparticles into dentine with iontophoresis. Caries Research, 48(5), (pp. 447). doi: 10.1159/000360836

Meledandri, C., & Schwass, D. (2013). Light triggered preparation of nano-silver composite materials: Towards new antimicrobial agents for treating dental caries. Caries Research, 47, (pp. 438). doi: 10.1159/000350670

Meledandri, C. J., Garden, A. L., & Schwass, D. R. (2013). Micelle-directed synthesis and assembly of silver nanocomposite materials: Toward new antimicrobial agents [Invited]. Proceedings of the Sixth International Conference on Advanced Materials and Nanotechnology (AMN6). [USB Memory Stick] [Abstract]

Dumas, C., & Meledandri, C. J. (2013). Addition of secondary surfactants to reverse micelles: Effects, and implications for nanoparticle synthesis. Proceedings of the Sixth International Conference on Advanced Materials and Nanotechnology (AMN6). [USB Memory Stick] [Abstract]

Meledandri, C. J., Stolarczyk, J. K., & Brougham, D. F. (2011). Development of magnetic nanoparticle assemblies with selectable size and tunable properties. Proceedings of the Fifth International Conference on Advanced Materials and Nanotechnology (AMN-5). Retrieved from http://www.confer.co.nz/amn-5/pdf/4%20Friday/C34.1.pdf

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Conference Contribution - Verbal presentation and other Conference outputs

Meledandri, C., Lucas, N., Rodpun, K., & Tan, E. (2015, February). Size-controlled, solvent-dispersible coordination polymer nanocrystals: Preparation and catalytic activity. Verbal presentation at the Seventh International Conference on Advanced Materials & Nanotechnology (AMN-7), Nelson, New Zealand.

Meledandri, C. (2015, November). Silver nanocomposite materials: Toward new antimicrobial agents for dental application. Verbal presentation at the Diagnostic Drug Device Discovery (D4) Conference, Dunedin, New Zealand.

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