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Dr Mohamed Sharafeldin

Mohamed Sharafeldin imagePhD

Location: Science II, 2n9
Email: mohamed.sharafeldin@otago.ac.nz

Research Interests

Mohamed Sharafeldin is a lecturer of Chemistry at University of Otago, NZ.

He got his PhD in Chemistry from University of Connecticut, USA in 2019 under professor James Rusling. He then worked as postdoctoral research associate at the department of chemistry, University of Oxford (UK) between 2019-2022.

His research is focusing on the development of disease diagnostics at the point of care utilising modern microfluidic fabrication techniques, electrochemistry, chemiluminescence, colorimetric sesnors, biomarker isolation and validation.

https://blogs.otago.ac.nz/sharafeldin/

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Publications

Sharafeldin, M., Fleschhut, F., James, T., & Davis, J. J. (2022). A quantification of target protein biomarkers in complex media by Faradaic shotgun tagging. Analytical Chemistry, 94, 2375-2382. doi: 10.1021/acs.analchem.1c03695

Sharafeldin, M., & Davis, J. J. (2022). Characterising the biosensing interface. Analytica Chimica Acta, 339759. Advance online publication. doi: 10.1016/j.aca.2022.339759

Sharafeldin, M., James, T., & Davis, J. J. (2021). Open circuit potential as a tool for the assessment of binding kinetics and reagentless protein quantitation. Analytical Chemistry, 93, 14748-14754. doi: 10.1021/acs.analchem.1c03292

Jones, A. L., Dhanapala, L., Baldo, T. A., Sharafeldin, M., Krause, C. E., Shen, M., … Rusling, J. F. (2021). Prostate cancer diagnosis in the clinic using an 8-protein biomarker panel. Analytical Chemistry, 93, 1059-1067. doi: 10.1021/acs.analchem.0c04034

Sharafeldin, M., & Davis, J. J. (2021). Point of care sensors for infectious pathogens. Analytical Chemistry, 93, 184-197. doi: 10.1021/acs.analchem.0c04677

Sharafeldin, M., & Davis, J. J. (2022). Characterising the biosensing interface. Analytica Chimica Acta, 339759. Advance online publication. doi: 10.1016/j.aca.2022.339759

Journal - Research Article

Sharafeldin, M., Fleschhut, F., James, T., & Davis, J. J. (2022). A quantification of target protein biomarkers in complex media by Faradaic shotgun tagging. Analytical Chemistry, 94, 2375-2382. doi: 10.1021/acs.analchem.1c03695

Journal - Research Article

Jones, A. L., Dhanapala, L., Baldo, T. A., Sharafeldin, M., Krause, C. E., Shen, M., … Rusling, J. F. (2021). Prostate cancer diagnosis in the clinic using an 8-protein biomarker panel. Analytical Chemistry, 93, 1059-1067. doi: 10.1021/acs.analchem.0c04034

Journal - Research Article

Patrick, S. C., Hein, R., Sharafeldin, M., Li, X., Beer, P. D., & Davis, J. J. (2021). Real-time voltammetric anion sensing under flow. Chemistry: A European Journal, 27, 17700-17706. doi: 10.1002/chem.202103249

Journal - Research Article

Sharafeldin, M., Chen, T., Ozkaya, G. U., Choudhary, D., Molinolo, A. A., Gutkind, J. S., & Rusling, J. F. (2021). Detecting cancer metastasis and accompanying protein biomarkers at single cell levels using a 3D-printed microfluidic immunoarray. Biosensors & Bioelectronics, 171, 112681. doi: 10.1016/j.bios.2020.112681

Journal - Research Article

Sharafeldin, M., James, T., & Davis, J. J. (2021). Open circuit potential as a tool for the assessment of binding kinetics and reagentless protein quantitation. Analytical Chemistry, 93, 14748-14754. doi: 10.1021/acs.analchem.1c03292

Journal - Research Article

Dutta, B., Wu, Y., Chen, J., Wang, J., He, J., Sharafeldin, M., … Suib, S. L. (2019). Partial surface selenization of cobalt sulfide microspheres for enhancing the hydrogen evolution reaction. ACS Catalysis, 9, 456-465. doi: 10.1021/acscatal.8b02904

Journal - Research Article

Sharafeldin, M., Kadimisetty, K., Bhalerao, K. R., Bist, I., Jones, A., Chen, T., … Rusling, J. F. (2019). Accessible telemedicine diagnostics with ELISA in a 3D printed pipette tip. Analytical Chemistry, 91, 7394-7402. doi: 10.1021/acs.analchem.9b01284

Journal - Research Article

Sharafeldin, M., McCaffrey, K., & Rusling, J. F. (2019). Influence of antibody immobilization strategy on carbon electrode immunoarrays. Analyst, 144, 5108-5116. doi: 10.1039/c9an01093a

Journal - Research Article

Sharafeldin, M., Bishop, G. W., Bhakta, S., El-Sawy, A., Suib, S. L., & Rusling, J. F. (2017). Fe3O4 nanoparticles on graphene oxide sheets for isolation and ultrasensitive amperometric detection of cancer biomarker proteins. Biosensors & Bioelectronics, 91, 359-366. doi: 10.1016/j.bios.2016.12.052

Journal - Research Article

Aboul-Kheir, A., Saleh, H., El-Henawee, M. M., & Sharf El-Din, M. N. (2012). Bromometric analysis of lamotrigine, minoxidil and cefixime. Asian Journal of Pharmaceutical Analysis, 2(1), 22-28.

Journal - Research Article

Aboul-Kheir, A., Saleh, H., El-Henawee, M. M., & Sharf El-Din, M. N. (2012). Spectrophotometric estimation of lamotrigine and minoxidil in bulk and dosage forms. Research Journal of Pharmacy & Technology, 5(5), 697-708.

Journal - Research Article

Aboul-Kheir, A., Saleh, H., El-Henawee, M. M., & Sharf El-Din, M. N. (2012). Spectrophotometric estimation of lisinopril and cefixime in bulk and dosage forms. Asian Journal of Pharmaceutical Analysis, 2(3), 90-97.

Journal - Research Article

Sharafeldin, M., & Davis, J. J. (2021). Point of care sensors for infectious pathogens. Analytical Chemistry, 93, 184-197. doi: 10.1021/acs.analchem.0c04677

Journal - Research Other

Sharafeldin, M., Kadimisetty, K., Bhalerao, K. S., Chen, T., & Rusling, J. F. (2020). 3D-printed immunosensor arrays for cancer diagnostics. Sensors, 20, 4514. doi: 10.3390/s20164514

Journal - Research Other

Ahmed, A., Hassan, I., Mosa, I. M., Elsanadidy, E., Sharafeldin, M., Rusling, J. F., & Ren, S. (2019). An ultra-shapeable, smart sensing platform based on a multimodal ferrofluid-infused surface. Advanced Materials, 31, 1807201. doi: 10.1002/adma.201807201

Journal - Research Other

Kadimisetty, K., Spak, A. P., Bhalerao, K. S., Sharafeldin, M., Mosa, I. M., Lee, N. H., & Rusling, J. F. (2018). Automated 4-sample protein immunoassays using 3D-printed microfluidics [Technical note]. Analytical Methods, 10, 4000-4006. doi: 10.1039/c8ay01271g

Journal - Research Other

Sharafeldin, M., Jones, A., & Rusling, J. F. (2018). 3D-printed biosensor arrays for medical diagnostics. Micromachines, 9, 394. doi: 10.3390/mi9080394

Journal - Research Other

Rusling, J. F., Sharafeldin, M., Chen, T., Jones, A. L., & DhanapalaMudiyanselage, L. (2020). Ultrasensitive 3D printed immunoarrays for protein detection down to single cell levels. ECS Meeting Abstracts, MA2020-01, (pp. 1908). doi: 10.1149/ma2020-01271908mtgabs

Conference Contribution - Published proceedings: Abstract

Jones, A. L., DhanapalaMudiyanselage, L., Baldo, T., Sharafeldin, M., Krause, C. E., Lee, N., & Rusling, J. F. (2019). Aggressive prostate cancer detection with an 8-protein biomarker panel. ECS Meeting Abstracts, MA2019-01, (pp. 2114). doi: 10.1149/ma2019-01/44/2114

Conference Contribution - Published proceedings: Abstract

Jones, A. L., Otieno, B. A., Sharafeldin, M., Joshi, A. A., Krause, C. E., & Rusling, J. F. (2016). Prostate cancer biomarker detection using a 16-sensor electrochemical microfluidic immunoarray. ECS Meeting Abstracts, MA2016-01, (pp. 1620). doi: 10.1149/ma2016-01/33/1620

Conference Contribution - Published proceedings: Abstract

Otieno, B. A., Mercer, C. P., Jones, A. L., Krause, C. E., Sharafeldin, M., Joshi, A. A., … Rusling, J. F. (2016). Electrochemical microfluidic immunoarray for assessment of aggressive Vs indolent forms of prostate cancer. ECS Meeting Abstracts, MA2016-01, (pp. 1627). doi: 10.1149/ma2016-01/33/1627

Conference Contribution - Published proceedings: Abstract

Sharafeldin, M., Bishop, G. W., Bhakta, S., & Rusling, J. F. (2016). Fe3O4 on graphene oxide nanosheets for electrochemical detection of cancer biomarker proteins. ECS Meeting Abstracts, MA2016-01, (pp. 2014). doi: 10.1149/ma2016-01/40/2014

Conference Contribution - Published proceedings: Abstract

Joshi, A., Sharafeldin, M., Otieno, B., Krause, C., & Bishop, G. (2015). Ultrasensitive diagnostic immunoarray platform for the assessment of aggressive vs non-aggressive forms of prostate cancer. Proceedings of the 250th American Chemical Society (ACS) National Meeting & Exposition. Retrieved from https://www.acs.org/

Conference Contribution - Published proceedings: Abstract

Sharafeldin, M. (2019). Microfluidic systems for cancer diagnostics (PhD). University of Connecticut, Storrs, CT. Retrieved from https://opencommons.uconn.edu/dissertations/2294/

Awarded Doctoral Degree

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