Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Professor Geoff Shaw

Geoffrey ShawClinical Professor

MB ChB FANZCA FCICM Hon FIPENZ

Email geoff.shaw@cdhb.govt.nz

Geoff is an intensive care specialist and Professor of Intensive Care at the University of Otago, Christchurch and an Adjunct Professor in the Department of Mechanical Engineering, University of Canterbury.

He is also the first clinician to be made an honorary fellow of the Institute of Professional Engineers of New Zealand.

Research Interests

Include:

  • Modelling and control of agitation-sedation
  • Insulin-glucose dynamics
  • Cardiovascular dynamics
  • Acute respiratory distress syndrome (ARDS) in critically ill patients

Other interests

Include:

  • Arguing why evidence based medicine might be bad for you
  • Building sundials
  • Cosmology

^ Top of page

Publications

Uyttendaele, V., Knopp, J. L., Stewart, K. W., Desaive, T., Benyó, B., Szabó-Némedi, N., … Shaw, G. M., & Chase, J. G. (2018). A 3D insulin sensitivity prediction model enables more patient-specific prediction and model-based glycaemic control. Biomedical Signal Processing & Control, 46, 192-200. doi: 10.1016/j.bspc.2018.05.032

Zhou, T., Dickson, J. L., Shaw, G. M., & Chase, J. G. (2018). Continuous glucose monitoring measures can be used for glycemic control in the ICU: An in-silico study. Journal of Diabetes Science & Technology, 12(1), 7-19. doi: 10.1177/1932296817738791

Dickson, J. L., Stewart, K. W., Pretty, C. G., Flechet, M., Desaive, T., Penning, S., … Shaw, G. M., & Chase, J. G. (2018). Generalisability of a virtual trials method for glycaemic control in intensive care. IEEE Transactions on Biomedical Engineering, 65(7), 1543-1553. doi: 10.1109/TBME.2017.2686432

Gaddam, R. R., Chambers, S., Murdoch, D., Shaw, G., & Bhatia, M. (2017). Circulating levels of hydrogen sulfide and substance P in patients with sepsis. Journal of Infection, 75(4), 293-300. doi: 10.1016/j.jinf.2017.07.005

Carr, A. C., Rosengrave, P. C., Bayer, S., Chambers, S., Mehrtens, J., & Shaw, G. M. (2017). Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes. Critical Care, 21, 300. doi: 10.1186/s13054-017-1891-y

Chapter in Book - Research

Chase, J. G., Benyo, B., Desaive, T., Fisk, L., Dickson, J. L., Penning, S., … Shaw, G. M. (2013). Uncertainty, safety, and performance: A generalizable approach to risk- based (therapeutic) decision making. In A. Agah (Ed.), Medical applications of artificial intelligence. (pp. 233-246). Boca Raton, FL: CRC Press.

^ Top of page

Chapter in Book - Other

Shaw, G. M. (2000). High frequency ventilation: The quest to minimise lung injury. In Australasian Anaesthesia. (pp. 181-190). Australian and New Zealand College of Anaesthetists.

^ Top of page

Journal - Research Article

Uyttendaele, V., Knopp, J. L., Stewart, K. W., Desaive, T., Benyó, B., Szabó-Némedi, N., … Shaw, G. M., & Chase, J. G. (2018). A 3D insulin sensitivity prediction model enables more patient-specific prediction and model-based glycaemic control. Biomedical Signal Processing & Control, 46, 192-200. doi: 10.1016/j.bspc.2018.05.032

Dickson, J. L., Stewart, K. W., Pretty, C. G., Flechet, M., Desaive, T., Penning, S., … Shaw, G. M., & Chase, J. G. (2018). Generalisability of a virtual trials method for glycaemic control in intensive care. IEEE Transactions on Biomedical Engineering, 65(7), 1543-1553. doi: 10.1109/TBME.2017.2686432

Zhou, T., Dickson, J. L., Shaw, G. M., & Chase, J. G. (2018). Continuous glucose monitoring measures can be used for glycemic control in the ICU: An in-silico study. Journal of Diabetes Science & Technology, 12(1), 7-19. doi: 10.1177/1932296817738791

Gaddam, R. R., Chambers, S., Murdoch, D., Shaw, G., & Bhatia, M. (2017). Circulating levels of hydrogen sulfide and substance P in patients with sepsis. Journal of Infection, 75(4), 293-300. doi: 10.1016/j.jinf.2017.07.005

Carr, A. C., Rosengrave, P. C., Bayer, S., Chambers, S., Mehrtens, J., & Shaw, G. M. (2017). Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes. Critical Care, 21, 300. doi: 10.1186/s13054-017-1891-y

Dickson, J. L., Chase, J. G., Lynn, A., & Shaw, G. M. (2017). Model-based glycaemic control: Methodology and initial results from neonatal intensive care. Biomedical Engineering/Biomedizinische Technik, 62(2), 225-233. doi: 10.1515/bmt-2016-0051

Khan, M., Pretty, C. G., Amies, A. C., Balmer, J., Banna, H. E., Shaw, G. M., & Chase, J. G. (2017). Proof of concept non-invasive estimation of peripheral venous oxygen saturation. BioMedical Engineering OnLine, 16, 60. doi: 10.1186/s12938-017-0351-x

Kelly, H. E., Shaw, G. M., Brett, C. N., Greenwood, F. M., & Huckabee, M. L. (2016). The effect of titrated fentanyl on suppressed cough reflex in healthy adult volunteers. Anaesthesia, 71, 529-534. doi: 10.1111/anae.13410

Khan, M., Pretty, C. G., Amies, A. C., Elliott, R., Chiew, Y. S., Shaw, G. M., & Chase, J. G. (2016). Analysing the effects of cold, normal, and warm digits on transmittance pulse oximetry. Biomedical Signal Processing & Control, 26, 34-41. doi: 10.1016/j.bspc.2015.12.006

Lindsay, A., Bernard, A., Davidson, S. M., Redmond, D. P., Chiew, Y. S., Pretty, C., … Shaw, G. M., Gieseg, S. P., & Draper, N. (2016). Lung injury and respiratory mechanics in rugby union. Journal of Sports Medicine & Physical Fitness, 56(4), 450-457.

Stewart, K. W., Pretty, C. G., Tomlinson, H., Thomas, F. L., Homlok, J., Némedi Noémi, S., … Shaw, G. M., … Chase, J. G. (2016). Safety, efficacy and clinical generalization of the STAR protocol: A retrospective analysis. Annals of Intensive Care, 6, 24. doi: 10.1186/s13613-016-0125-9

Penning, S., Pretty, C., Preiser, J.-C., Shaw, G. M., Desaive, T., & Chase, J. G. (2015). Glucose control positively influences patient outcome: A retrospective study. Journal of Critical Care, 30, 455-459. doi: 10.1016/j.jcrc.2014.12.013

Carr, A. C., Shaw, G. M., Fowler, A. A., & Natarajan, R. (2015). Ascorbate-dependent vasopressor synthesis: A rationale for vitamin C administration in severe sepsis and septic shock? Critical Care, 19, 418. doi: 10.1186/s13054-015-1131-2

Young, P., Saxena, M., Bellomo, R., Freebairn, R., Hammond, N., van Haren, F., … Henderson, S., … Weatherall, M., … Beasley, R., for the HEAT Investigators, and the Australian and New Zealand Intensive Care Society Clinical Trials Group, including Shaw, G., Bailey, M., & Psirides, A. (2015). Acetaminophen for fever in critically ill patients with suspected infection. New England Journal of Medicine, 373, 2215-2224. doi: 10.1056/NEJMoa1508375

Chiew, Y. S., Pretty, C., Docherty, P. D., Lambermont, B., Shaw, G. M., Desaive, T., & Chase, J. G. (2015). Time-varying respiratory system elastance: A physiological model for patients who are spontaneously breathing. PLoS ONE, 10(1), e0114847. doi: 10.1371/journal.pone.0114847

Stewart, K. W., Pretty, C. G., Tomlinson, H., Fisk, L., Shaw, G. M., & Chase, J. G. (2015). Stochastic Model Predictive (STOMP) glycaemic control for the intensive care unit: Development and virtual trial validation. Biomedical Signal Processing & Control, 16, 61-67. doi: 10.1016/j.bspc.2014.09.011

Pretty, C. G., Le Compte, A., Penning, S., Fisk, L., Shaw, G. M., Desaive, T., & Chase, J. G. (2014). Interstitial insulin kinetic parameters for a 2-compartment insulin model with saturable clearance. Computer Methods & Programs in Biomedicine, 114(3), e39-e45. doi: 10.1016/j.cmpb.2014.01.011

Szlavecz, A., Chiew, Y. S., Redmond, D., Beatson, A., Glassenbury, D., Corbett, S., … Shaw, G. M., … Chase, J. G. (2014). The Clinical Utilisation of Respiratory Elastance Software (CURE Soft): A bedside software for real-time respiratory mechanics monitoring and mechanical ventilation management. BioMedical Engineering OnLine, 13, 140. doi: 10.1186/1475-925X-13-140

Redmond, D., Chiew, Y. S., van Drunen, E., Shaw, G. M., & Chase, J. G. (2014). A minimal algorithm for a minimal recruitment model—model estimation of alveoli opening pressure of an acute respiratory distress syndrome (ARDS) lung. Biomedical Signal Processing & Control, 14, 1-8. doi: 10.1016/j.bspc.2014.05.006

Thomas, F., Pretty, C. G., Fisk, L., Shaw, G. M., Chase, J. G., & Desaive, T. (2014). Reducing the impact of insulin sensitivity variability on glycaemic outcomes using separate stochastic models within the STAR glycaemic protocol. BioMedical Engineering OnLine, 13, 43. doi: 10.1186/1475-925X-13-43

Kamoi, S., Pretty, C., Docherty, P., Squire, D., Revie, J., Chiew, Y. S., … Shaw, G. M., & Chase, J. G. (2014). Continuous stroke volume estimation from aortic pressure using zero dimensional cardiovascular model: Proof of concept study from porcine experiments. PLoS ONE, 9(7), e102476. doi: 10.1371/journal.pone.0102476

Thomas, F., Signal, M., Harris, D. L., Weston, P. J., Harding, J. E., Shaw, G. M., … on behalf of the CHYLD Study Group. (2014). Continuous glucose monitoring in newborn infants: How do errors in calibration measurements affect detected hypoglycemia? Journal of Diabetes Science & Technology, 8(3), 543-550. doi: 10.1177/1932296814524857

Pretty, C. G., Signal, M., Fisk, L., Penning, S., Le Compte, A., Shaw, G. M., … Chase, J. G. (2014). Impact of sensor and measurement timing errors on model-based insulin sensitivity. Computer Methods & Programs in Biomedicine, 114(3), e79-e86. doi: 10.1016/j.cmpb.2013.08.007

Sah Pri, A., Chase, J. G., Pretty, C. G., Shaw, G. M., Preiser, J.-C., Vincent, J.-L., … Desaive, T. (2014). Evolution of insulin sensitivity and its variability in out-of-hospital cardiac arrest (OHCA) patients treated with hypothermia. Critical Care, 18, 586. doi: 10.1186/s13054-014-0586-x

van Drunen, E. J., Chiew, Y. S., Pretty, C., Shaw, G. M., Lambermont, B., Janssen, N., … Desaive, T. (2014). Visualisation of time-varying respiratory system elastance in experimental ARDS animal models. BMC Pulmonary Medicine, 14, 33. doi: 10.1186/1471-2466-14-33

Ralib, A. M., Pickering, J. W., Shaw, G. M., Than, M. P., George, P. M., & Endre, Z. H. (2014). The clinical utility window for acute kidney injury biomarkers in the critically ill. Critical Care, 18, 601. doi: 10.1186/s13054-014-0601-2

Willis, J. G., Fisk, L., Razak, N., Le Compte, A., Shaw, G. M., & Chase, J. G. (2013). Insulin Glargine in the intensive care unit: A model-based clinical trial design. Biomedical Signal Processing & Control, 8(2), 120-129. doi: 10.1016/j.bspc.2012.09.004

Desaive, T., Lambermont, B., Janssen, N., Ghuysen, A., Kolh, P., Morimont, P., … Shaw, G. M., & Chase, J. G. (2013). Assessment of ventricular contractility and ventricular-arterial coupling with a model-based sensor. Computer Methods & Programs in Biomedicine, 109(2), 182-189. doi: 10.1016/j.cmpb.2011.11.009

Revie, J. A., Stevenson, D. J., Chase, J. G., Hann, C. E., Lambermont, B. C., Ghuysen, A., … Shaw, G. M., … Desaive, T. (2013). Validation of subject-specific cardiovascular system models from porcine measurements. Computer Methods & Programs in Biomedicine, 109(2), 197-210. doi: 10.1016/j.cmpb.2011.10.013

Dickson, J. L., Hewett, J. N., Gunn, C. A., Lynn, A., Shaw, G. M., & Chase, J. G. (2013). On the problem of patient-specific endogenous glucose production in neonates on stochastic targeted glycemic control. Journal of Diabetes Science & Technology, 7(4), 913-927. doi: 10.1177/193229681300700414

Ferenci, T., Benyó, B., Kovács, L., Fisk, L., Shaw, G. M., & Chase, J. G. (2013). Daily evolution of insulin sensitivity variability with respect to diagnosis in the critically ill. PLoS ONE, 8(2), e57119. doi: 10.1371/journal.pone.0057119

Revie, J. A., Stevenson, D., Chase, J. G., Pretty, C. J., Lambermont, B. C., Ghuysen, A., … Shaw, G. M., & Desaive, T. (2013). Evaluation of a model-based hemodynamic monitoring method in a porcine study of septic shock. Computational & Mathematical Methods in Medicine, 2013, 505417. doi: 10.1155/2013/505417

Le Compte, A. J., Pretty, C. G., Lin, J., Shaw, G. M., Lynn, A., & Chase, J. G. (2013). Impact of variation in patient response on model-based control of glycaemia in critically ill patients. Computer Methods & Programs in Biomedicine, 109(2), 211-219. doi: 10.1016/j.cmpb.2011.08.007

Docherty, P. D., Berkeley, J. E., Lotz, T. F., Te Morenga, L., Fisk, L. M., Shaw, G. M., McAuley, K. A., Mann, J. I., & Chase, J. G. (2013). Clinical validation of the quick dynamic insulin sensitivity test. IEEE Transactions on Biomedical Engineering, 60(5), 1266-1272. doi: 10.1109/TBME.2012.2232667

Ralib, A. M., Pickering, J. W., Major, T., Palmer, S. C., Shaw, G. M., Goodkin, D. A., & Endre, Z. H. (2013). High-dose intravenous epoetin does not increase blood pressure in critically ill patients with acute kidney injury. Clinical Nephrology, 79(5), 370-379. doi: 10.5414/cn107673

Dickson, J. L., Le Compte, A. J., Floyd, R. P., Chase, J. G., Lynn, A., & Shaw, G. M. (2013). Development and optimisation of stochastic targeted (STAR) glyceamic control for pre-term infants in neonatal intensive care. Biomedical Signal Processing & Control, 8(2), 215-221.

Dickson, J. L., Floyd, R. P., Le Compte, A. J., Fisk, L. M., Chase, J. G., Lynn, A., & Shaw, G. M. (2013). External validation and sub-cohort analysis of stochastic forecasting models in NICU cohorts. Biomedical Signal Processing & Control, 8(4), 409-419. doi: 10.1016/j.bspc.2013.01.006

van Drunen, E. J., Chiew, Y. S., Chase, J. G., Shaw, G. M., Lambermont, B., Janssen, N., … Desaive, T. (2013). Expiratory model-based method to monitor ARDS disease state. BioMedical Engineering OnLine, 12, 57. doi: 10.1186/1475-925X-12-57

Gunn, C. A., Dickson, J. L., Hewett, J. N., Lynn, A., Rose, H. J., Shaw, G. M., … Chase, J. G. (2013). Nasogastric aspiration as an indicator for feed absorption in model-based glycemic control in neonatal intensive care. Journal of Diabetes Science & Technology, 7(3), 717-726. doi: 10.1177/193229681300700317

Md Ralib, A., Pickering, J. W., Shaw, G. M., & Endre, Z. H. (2013). The urine output definition of acute kidney injury is too liberal. Critical Care, 17, R112. doi: 10.1186/cc12784

van Drunen, E. J., Chase, J. G., Chiew, Y. S., Shaw, G. M., & Desaive, T. (2013). Analysis of different model-based approaches for estimating dFRC for real-time application. BioMedical Engineering OnLine, 12, 9. doi: 10.1186/1475-925X-12-9

Chiew, Y. S., Chase, J. G., Lambermont, B., Janssen, N., Schranz, C., Moeller, K., Shaw, G. M., & Desaive, T. (2013). Physiological relevance and performance of a minimal lung model: An experimental study in healthy and acute respiratory distress syndrome model piglets. BMC Pulmonary Medicine, 12, 59. doi: 10.1186/1471-2466-12-59

Signal, M., Thomas, F., Shaw, G. M., & Chase, J. G. (2013). Complexity of continuous glucose monitoring data in critically ill patients: Continuous glucose monitoring devices, sensor locations, and detrended fluctuation analysis methods. Journal of Diabetes Science & Technology, 7(6), 1492-1506. doi: 10.1177/193229681300700609

Le Compte, A. J., Lynn, A. M., Lin, J., Pretty, C. G., Shaw, G. M., & Chase, J. G. (2012). Pilot study of a model-based approach to blood glucose control in very-low-birthweight neonates. BMC Pediatrics, 12, 117. doi: 10.1186/1471-2431-12-117

Stevenson, D., Revie, J., Chase, J. G., Hann, C. E., Shaw, G. M., Lambermont, B., … Desaive, T. (2012). Beat-to-beat estimation of the continuous left and right cardiac elastance from metrics commonly available in clinical settings. BioMedical Engineering OnLine, 11, 73. doi: 10.1186/1475-925X-11-73

Pretty, C. G., Le Compte, A. J., Chase, J. G., Shaw, G. M., Preiser, J.-C., Penning, S., & Desaive, T. (2012). Variability of insulin sensitivity during the first 4 days of critical illness: Implications for tight glycemic control. Annals of Intensive Care, 2, 17. doi: 10.1186/2110-5820-2-17

Evans, A., Le Compte, A., Tan, C.-S., Ward, L., Steel, J., Pretty, C. G., … Shaw, G. M., … Chase, J. G. (2012). Stochastic targeted (STAR) glycemic control: Design, safety, and performance. Journal of Diabetes Science & Technology, 6(1), 102-115. doi: 10.1177/193229681200600113

Ward, L., Steel, J., Le Compte, A., Evans, A., Tan, C.-S., Penning, S., Shaw, G. M., … Chase, J. G. (2012). Data entry errors and design for model-based tight glycemic control in critical care. Journal of Diabetes Science & Technology, 6(1), 135-143. doi: 10.1177/193229681200600116

More publications...