Professor Geoffrey Shaw, Our people, University of Otago, Christchurch

Clinical Professor

MB ChB FANZCA FCICM Hon FIPENZ

Geoff is an intensive care specialist and Professor of Intensive Care at the University of Otago, Christchurch and an Adjunct Professor in the Department of Mechanical Engineering, University of Canterbury.

He is also the first clinician to be made an honorary fellow of the Institute of Professional Engineers of New Zealand.

Research Interests

Include:

Modelling and control of agitation-sedation
Insulin-glucose dynamics
Cardiovascular dynamics
Acute respiratory distress syndrome (ARDS) in critically ill patients

Other interests

Include:

Arguing why evidence based medicine might be bad for you
Building sundials
Cosmology

Publications

Knopp, J. L., Chiew, Y. S., Georgopoulos, D., Shaw, G. M., & Chase, J. G. (2024). Ubiquity of models describing inspiratory effort dynamics in patients on pressure support ventilation. IFAC Journal of Systems and Control, 27, 100250. doi: 10.1016/j.ifacsc.2024.100250 Journal - Research Article

Angriman, F., Muttalib, F., Lamontagne, F., Adhikari, N. K. J., LOVIT Investigators, including Shaw, G., Burke, B., Closey, D., Henderson, S., Hitchings, L., Smith, M., Waibel, H. A., Moore, J., Psirides, A., Tietjens, K., & Ure, B. (2023). IV vitamin C in adults with sepsis: A Bayesian reanalysis of a randomized controlled trial [Brief report]. Critical Care Medicine, 51(8), e152. doi: 10.1097/ccm.0000000000005871 Journal - Research Other

Angriman, F., Muttalib, F., Lamontagne, F., Adhikari, N. K. J., LOVIT Investigators, including Shaw, G., Burke, B., Closey, D., Henderson, S., Hitchings, L., Smith, M., Waibel, H., Moore, J., Psirides, A., Tietjens, K., & Ure, B. (2023). The authors reply [Reply to the letter Apples and oranges: All 'vitamin C' may not be created equal]. Critical Care Medicine, 51(12), e283-e284. doi: 10.1097/ccm.0000000000006054 Journal - Research Other

Rosengrave, P. C., Wohlrab, C., Spencer, E., Williman, J., Shaw, G., & Carr, A. C. (2022). Effect of intravenous vitamin C on arterial blood gas analyser and Accu-Chek point-of-care glucose monitoring in critically ill patients. Critical Care & Resuscitation, 24(2), 175-182. doi: 10.51893/2022.2.Oa7 Journal - Research Article

Vlasiuk, E., Rosengrave, P., Roberts, E., Boden, J. M., Shaw, G., & Carr, A. C. (2022). Critically ill septic patients have elevated oxidative stress biomarkers: Lack of attenuation by parenteral vitamin C. Nutrition Research, 108, 53-59. doi: 10.1016/j.nutres.2022.10.010 Journal - Research Article

2024

Journal - Research Article

2023

Journal - Research Other

Angriman, F., Muttalib, F., Lamontagne, F., Adhikari, N. K. J., LOVIT Investigators, including Shaw, G., Burke, B., Closey, D., Henderson, S., Hitchings, L., Smith, M., Waibel, H., Moore, J., Psirides, A., Tietjens, K., & Ure, B. (2023). The authors reply [Reply to the letter Apples and oranges: All 'vitamin C' may not be created equal]. Critical Care Medicine, 51(12), e283-e284. doi: 10.1097/ccm.0000000000006054

2022

Journal - Research Article

Lamontagne, F., Masse, M.-H., Menard, J., Sprague, S., Pinto, R., Heyland, D. K., … Twardowski, P., … for the LOVIT Investigators, and the Canadian Critical Care Trials Group, including Shaw, G., Burke, B., Henderson, S., Hitchings, L., Smith, M., Waibel, H. A., Moore, J., Psirides, A., Tietjens, K., & Ure, B. (2022). Intravenous vitamin C in adults with sepsis in the intensive care unit. New England Journal of Medicine, 386(25), 2387-2398. doi: 10.1056/NEJMoa2200644

Rosengrave, P., Spencer, E., Williman, J., Mehrtens, J., Morgan, S., Doyle, T., Van Der Heyden, K., … Shaw, G., & Carr, A. C. (2022). Intravenous vitamin C administration to patients with septic shock: A pilot randomised controlled trial. Critical Care, 26(1), 26. doi: 10.1186/s13054-022-03900-w

Spencer, E., Rosengrave, P., Williman, J., Shaw, G., & Carr, A. C. (2022). Circulating protein carbonyls are specifically elevated in critically ill patients with pneumonia relative to other sources of sepsis. Free Radical Biology & Medicine, 179, 208-212. doi: 10.1016/j.freeradbiomed.2021.11.029

Journal - Research Other

Adhikari, N. K. J., Pinto, R., Day, A. G., Masse, M.-H., Ménard, J., Sprague, S., … Twardowski, P., … LOVIT Investigators, including Shaw, G. (2022). Lessening Organ Dysfunction With Vitamin C (LOVIT) trial: Statistical analysis plan. JMIR Research Protocols, 11(5), e36261. doi: 10.2196/36261

2021

Journal - Research Article

Carr, A. C., Bozonet, S., Pullar, J., Spencer, E., Rosengrave, P., & Shaw, G. (2021). Neutrophils isolated from septic patients exhibit elevated uptake of vitamin C and normal intracellular concentrations despite a low vitamin C milieu. Antioxidants, 10(10), 1607. doi: 10.3390/antiox10101607

Parente, J. D., Chase, J. G., Moeller, K., & Shaw, G. M. (2021). High inter-patient variability in sepsis evolution: A hidden Markov model analysis. Computer Methods & Programs in Biomedicine, 201, 105956. doi: 10.1016/j.cmpb.2021.105956

Uyttendaele, V., Chase, J. G., Knopp, J. L., Gottlieb, R., Shaw, G. M., & Desaive, T. (2021). Insulin sensitivity in critically ill patients: are women more insulin resistant? Annals of Intensive Care, 11, 12. doi: 10.1186/s13613-021-00807-7

Balmer, J., Smith, R., Pretty, C. G., Desaive, T., Shaw, G. M., & Chase, J. G. (2021). Accurate end systole detection in dicrotic notch-less arterial pressure waveforms. Journal of Clinical Monitoring & Computing, 35(1), 79-88. doi: 10.1007/s10877-020-00473-3

Journal - Research Other

Chase, J. G., Shaw, G. M., Preiser, J.-C., Knopp, J. L., & Desaive, T. (2021). Risk-based care: Let's think outside the box. Frontiers in Medicine, 8, 535244. doi: 10.3389/fmed.2021.535244

2020

Journal - Research Article

The ICU-ROX Investigators, including Beasley, R., Freebairn, R., Burke, B., Henderson, S., Shaw, G., Barry, B., & Psirides, A. (2020). Conservative oxygen therapy during mechanical ventilation in the ICU. New England Journal of Medicine, 382(11), 989-998. doi: 10.1056/NEJMoa1903297

Young, P., Mackle, D., Bellomo, R., Bailey, M., Beasley, R., Deane, A., … Freebairn, R., … on behalf of the ICU-ROX Investigators, including Burke, B., Henderson, S., Shaw, G., Barry, B., Psirides, A., and the Australian and New Zealand Intensive Care Society Clinical Trials Group. (2020). Conservative oxygen therapy for mechanically ventilated adults with suspected hypoxic ischaemic encephalopathy. Intensive Care Medicine, 46(12), 2411-2422. doi: 10.1007/s00134-020-06196-y

Parente, J. D., Chase, J. G., Moeller, K., & Shaw, G. M. (2020). Quantifying misclassification and bias errors due to hierarchical sepsis scores in real-time sepsis diagnosis. Biomedical Signal Processing & Control, 62, 102116. doi: 10.1016/j.bspc.2020.102116

Parente, J. D., Chase, J. G., Möller, K., & Shaw, G. M. (2020). Kernel density estimates for sepsis classification. Computer Methods & Programs in Biomedicine, 188, 105295. doi: 10.1016/j.cmpb.2019.105295

Chase, J. G., Chiew, Y. S., Lambermont, B., Morimont, P., Shaw, G. M., & Desaive, T. (2020). Safe doubling of ventilator capacity: A last resort proposal for last resorts. Critical Care, 24, 222. doi: 10.1186/s13054-020-02945-z

Baxter-Parker, G., Gaddam, R. R., Moltchanova, E., Carr, A. C., Shaw, G., Chambers, S., & Gieseg, S. P. (2020). Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysis. Pteridines, 31(1), 68-82. doi: 10.1515/pteridines-2020-0015

Uyttendaele, P., Knopp, J. L., Shaw, G. M., Desaive, T., & Chase, J. G. (2020). Risk and reward: Extending stochastic glycaemic control intervals to reduce workload. BioMedical Engineering OnLine, 19, 26. doi: 10.1186/s12938-020-00771-6

Balmer, J., Pretty, C. G., Davidson, S., Mehta-Wilson, T., Desaive, T., Smith, R., Shaw, G. M., & Chase, J. G. (2020). Clinically applicable model-based method, for physiologically accurate flow waveform and stroke volume estimation. Computer Methods & Programs in Biomedicine, 185, 105125. doi: 10.1016/j.cmpb.2019.105125

Howe, S. L., Chase, J. G., Redmond, D. P., Morton, S. E., Kim, K. T., Shaw, G. M., … Desaive, T. (2020). Inspiratory respiratory mechanics estimation by using expiratory data for reverse-trigger breathing cycles. Computer Methods & Programs in Biomedicine, 186, 105184. doi: 10.1016/j.cmpb.2019.105184

Carr, A. C., Spencer, E., Hoskin, T. S., Rosengrave, P., Kettle, A. J., & Shaw, G. (2020). Circulating myeloperoxidase is elevated in septic shock and is associated with systemic organ failure and mortality in critically ill patients. Free Radical Biology & Medicine, 152, 462-468. doi: 10.1016/j.freeradbiomed.2019.11.004

Journal - Research Other

Wiltshire, E., Peña, A. S., MacKenzie, K., Shaw, G., & Couper, J. (2020). High dose folic acid is a potential treatment for pulmonary hypertension, including when associated with COVID-19 pneumonia. Medical Hypotheses, 143, 110142. doi: 10.1016/j.mehy.2020.110142

Conference Contribution - Published proceedings: Abstract

Spencer, E., Hoskin, T., Rosengrave, P., Kettle, A., Shaw, G., & Carr, A. (2020). Circulating myeloperoxidase is elevated in septic shock and is associated with systemic organ failure and mortality in critically ill patients. New Zealand Medical Journal, 133(1524), (pp. 145-146). Retrieved from https://www.nzma.org.nz/journal

2019

Journal - Research Article

Knopp, J. L., Lynn, A. M., Shaw, G. M., & Chase, J. G. (2019). Safe and effective glycaemic control in premature infants: Observational clinical results from the computerised STAR-GRYPHON protocol. Archives of Disease in Childhood: Fetal & Neonatal Edition, 104(2), F205-F211. doi: 10.1136/archdischild-2017-314072

Morton, S. E., Knopp, J. L., Chase, J. G., Möller, K., Docherty, P., Shaw, G. M., & Tawhai, M. (2019). Predictive virtual patient modelling of mechanical ventilation: Impact of recruitment function. Annals of Biomedical Engineering, 47(7), 1626-1641. doi: 10.1007/s10439-019-02253-w

Uyttendaele, V., Knopp, J. L., Shaw, G. M., Desaive, T., & Chase, J. G. (2019). Is intensive insulin therapy the scapegoat for or cause of hypoglycaemia and poor outcome. IFAC Journal of Systems and Control, 9, 100063. doi: 10.1016/j.ifacsc.2019.100063

Uyttendaele, V., Knopp, J. L., Davidson, S., Desaive, T., Benyo, B., Shaw, G. M., & Chase, J. G. (2019). 3D kernel-density stochastic model for more personalized glycaemic control: Development and in-silico validation. BioMedical Engineering OnLine, 18, 102. doi: 10.1186/s12938-019-0720-8

Journal - Research Other

Morton, S. E., Knopp, J. L., Chase, J. G., Docherty, P., Howe, S. L., Möller, K., Shaw, G. M., & Tawhai, M. (2019). Optimising mechanical ventilation through model-based methods and automation. Annual Reviews in Control, 48, 369-382. doi: 10.1016/j.arcontrol.2019.05.001

Conference Contribution - Published proceedings: Full paper

Klenner, J. B., Van Noorden, B. A., Knopp, J. L., Holder Pearson, L. R., Hardy, A. R., Vergeer, S. L., Shaw, G. M., & Chase, J. G. (2019). Determining the effects of insulin Detemir on endogenous secretion of insulin. Proceedings of the 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS). (pp. 2943-2946). IEEE. doi: 10.1109/EMBC.2019.8857643

Uyttendaele, V., Knopp, J. L., Pirotte, M., Morimont, P., Lambermont, B., Shaw, G. M., … Chase, J. G. (2019). STAR-Liège clinical trial interim results: Safe and effective glycemic control for all. Proceedings of the 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS). (pp. 277-280). IEEE. doi: 10.1109/EMBC.2019.8856303

2018

Journal - Research Article

Stewart, K. W., Chase, J. G., Pretty, C. G., & Shaw, G. M. (2018). Nutrition delivery of a model-based ICU glycaemic control system. Annals of Intensive Care, 8, 4. doi: 10.1186/s13613-017-0351-9

Chase, J. G., Preiser, J.-C., Dickson, J. L., Pironet, A., Chiew, Y. S., Pretty, C. G., Shaw, G. M., … Desaive, T. (2018). Next-generation, personallsed model-based critical care medicine: A state-of-the-art review of in silico virtual patient models, methods and cohorts, and how to validate them. BioMedical Engineering OnLine, 17, 24. doi: 10.1186/s12938-018-0455-y

Stewart, K. W., Pretty, C. G., Shaw, G. M., & Chase, J. G. (2018). Creating smooth SI. B-spline basis function representations of insulin sensitivity. Biomedical Signal Processing & Control, 44, 270-278. doi: 10.1016/j.bspc.2018.05.001

Stewart, K. W., Pretty, C. G., Shaw, G. M., & Chase, J. G. (2018). Interpretation of retrospective BG measurements. Journal of Diabetes Science & Technology, 12(5), 967-975. doi: 10.1177/1932296818786518

Morton, S. E., Dickson, J., Chase, J. G., Docherty, P., Desaive, T., Howe, S. L., Shaw, G. M., & Tawhai, M. (2018). A virtual patient model for mechanical ventilation. Computer Methods & Programs in Biomedicine, 165, 77-87. doi: 10.1016/j.cmpb.2018.08.004

Stewart, K. W., Chase, J. G., Pretty, C. G., & Shaw, G. M. (2018). Nutrition delivery, workload and performance in a model-based ICU glycaemic control system. Computer Methods & Programs in Biomedicine, 166, 9-18. doi: 10.1016/j.cmpb.2018.09.005

Balmer, J., Pretty, C., Davidson, S., Desaive, T., Kamoi, S., Pironet, A., … Shaw, G. M., & Chase, J. G. (2018). Pre-ejection period, the reason why the electrocardiogram Q-wave is an unreliable indicator of pulse wave initialization. Physiological Measurement, 39(9), 095005. doi: 10.1088/1361-6579/aada72

Major, V. J., Chiew, Y. S., Shaw, G. M., & Chase, J. G. (2018). Biomedical engineer's guide to the clinical aspects of intensive care mechanical ventilation. BioMedical Engineering OnLine, 17, 169. doi: 10.1186/s12938-018-0599-9

Uyttendaele, V., Knopp, J. L., Stewart, K. W., Desaive, T., Benyó, B., Szabó-Némedi, N., … Shaw, G. M., & Chase, J. G. (2018). A 3D insulin sensitivity prediction model enables more patient-specific prediction and model-based glycaemic control. Biomedical Signal Processing & Control, 46, 192-200. doi: 10.1016/j.bspc.2018.05.032

Dickson, J. L., Stewart, K. W., Pretty, C. G., Flechet, M., Desaive, T., Penning, S., … Shaw, G. M., & Chase, J. G. (2018). Generalisability of a virtual trials method for glycaemic control in intensive care. IEEE Transactions on Biomedical Engineering, 65(7), 1543-1553. doi: 10.1109/TBME.2017.2686432

Zhou, T., Dickson, J. L., Shaw, G. M., & Chase, J. G. (2018). Continuous glucose monitoring measures can be used for glycemic control in the ICU: An in-silico study. Journal of Diabetes Science & Technology, 12(1), 7-19. doi: 10.1177/1932296817738791

Conference Contribution - Published proceedings: Full paper

Parente, J. D., Möller, K., Shaw, G. M., & Chase, J. G. (2018). Hidden Markov models for sepsis. IFAC PapersOnLine, 51(27), (pp. 110-115). doi: 10.1016/j.ifacol.2018.11.658

Morton, S. E., Knopp, J. L., Chase, J. G., Docherty, P. D., Howe, S. L., Shaw, G. M., & Tawhai, M. (2018). Development of a predictive pulmonary elastance model to describe lung mechanics throughout recruitment manoeuvres. IFAC PapersOnLine, 51(27), (pp. 215-220). doi: 10.1016/j.ifacol.2018.11.640

Howe, S. L., Chase, J. G., Redmond, D. P., Morton, S. E., Kim, K. T., Pretty, C., Shaw, G. M., … Desaive, T. (2018). Estimation of inspiratory respiratory elastance using expiratory data. IFAC PapersOnLine, 51(27), (pp. 204-208). doi: 10.1016/j.ifacol.2018.11.642

Uyttendaele, V., Knopp, J. L., Shaw, G. M., Desaive, T., & Chase, J. G. (2018). Improved 3D stochastic modelling of insulin sensitivity variability for improved glycaemic control. IFAC PapersOnLine, 51(27), (pp. 198-203). doi: 10.1016/j.ifacol.2018.11.643

Uyttendaele, V., Knopp, J. L., Pirotte, M., Guiot, J., Morimont, P., Lambermont, B., Shaw, G. M., … Chase, J. G. (2018). Preliminary results from the STAR-Liège clinical trial: Virtual trials, safety, performance, and compliance analysis. IFAC PapersOnLine, 51(27), (pp. 355-360). doi: 10.1016/j.ifacol.2018.11.614

Morton, S. E., Knopp, J. L., Docherty, P. D., Shaw, G. M., & Chase, J. G. (2018). Validation of a model-based method for estimating functional volume gains during recruitment manoeuvres in mechanical ventilation. IFAC PapersOnLine, 51(27), (pp. 231-236). doi: 10.1016/j.ifacol.2018.11.637

Hardy, A. R., Dickson, J. L., Shaw, G. M., & Chase, J. G. (2018). Comparison of modulated and clinically set nutrition protocol's for STAR. IFAC PapersOnLine, 51(27), (pp. 384-389). doi: 10.1016/j.ifacol.2018.11.608

Uyttendaele, V., Knopp, J. L., Shaw, G. M., Desaive, T., & Chase, J. G. (2018). 3D stochastic modelling of insulin sensitivity in STAR: Virtual trials analysis. IFAC PapersOnLine, 51(27), (pp. 128-133). doi: 10.1016/j.ifacol.2018.11.655

Morton, S. E., Dickson, J. L., Chase, J. G., Docherty, P. D., Howe, S. L., Shaw, G. M., & Tawhai, M. (2018). Basis function identification of lung mechanics in mechanical ventilation for predicting outcomes of therapy changes: A first virtual patient. IFAC PapersOnLine, 51(15), (pp. 299-304). doi: 10.1016/j.ifacol.2018.09.151

Uyttendaele, V., Dickson, J. L., Morton, S., Shaw, G., Desaive, T., & Chase, J. G. (2018). Changes in identified, model-based insulin sensitivity can be used to improve risk and variability forecasting in glycaemic control. IFAC PapersOnLine, 51(15), (pp. 311-316). doi: 10.1016/j.ifacol.2018.09.153

Zhou, T., Knopp, J., Shaw, G. M., & Chase, J. G. (2018). An in-silico study of using continuous glucose monitoring measures for glycaemic control in the ICU. IFAC PapersOnLine, 51(27), (pp. 361-366). doi: 10.1016/j.ifacol.2018.11.613

Conference Contribution - Verbal presentation and other Conference outputs

Balázs, B., Stewart, K., Uyttendaele, V., Dickson, J. L., Ákos, S., Attila, I., … Shaw, G. M., … Chase, G. (2018, May). Személyre szabott inzulin terápia és táplálás az intenziv ápolásban a kezelési eredmények tükrében. Verbal presentation at the Magyar Aneszteziológiai és Intenzív Terápiás Társaság (MAITT) Nemzeti Kongresszusa, Budapest, Hungary.

2017

Journal - Research Article

Morton, S. E., Chiew, Y. S., Pretty, C., Moltchanova, E., Scarrott, C., Redmond, D., Shaw, G. M., & Chase, J. G. (2017). Effective sample size estimation for a mechanical ventilation trial through Monte-Carlo simulation: Length of mechanical ventilation and ventilator free days. Mathematical Biosciences, 4, 21-31. doi: 10.1016/j.mbs.2016.06.001

Kamoi, S., Pretty, C., Balmer, J., Davidson, S., Pironet, A., Desaive, T., Shaw, G. M., & Chase, J. G. (2017). Improved pressure contour analysis for estimating cardiac stroke volume using pulse wave velocity measurement. BioMedical Engineering OnLine, 16, 51. doi: 10.1186/s12938-017-0341-z

Khan, M., Pretty, C. G., Amies, A. C., Balmer, J., Banna, H. E., Shaw, G. M., & Chase, J. G. (2017). Proof of concept non-invasive estimation of peripheral venous oxygen saturation. BioMedical Engineering OnLine, 16, 60. doi: 10.1186/s12938-017-0351-x

Carr, A. C., Rosengrave, P. C., Bayer, S., Chambers, S., Mehrtens, J., & Shaw, G. M. (2017). Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes. Critical Care, 21, 300. doi: 10.1186/s13054-017-1891-y

Gaddam, R. R., Chambers, S., Murdoch, D., Shaw, G., & Bhatia, M. (2017). Circulating levels of hydrogen sulfide and substance P in patients with sepsis. Journal of Infection, 75(4), 293-300. doi: 10.1016/j.jinf.2017.07.005

Dickson, J. L., Chase, J. G., Lynn, A., & Shaw, G. M. (2017). Model-based glycaemic control: Methodology and initial results from neonatal intensive care. Biomedical Engineering / Biomedizinische Technik, 62(2), 225-233. doi: 10.1515/bmt-2016-0051

Conference Contribution - Published proceedings: Full paper

Stewart, K. W., Pretty, C., Chase, J. G., & Shaw, G. M. (2017). The effect of variable vs fixed feeding on glycaemic control in the adult ICU: Virtual trial evaluation. IFAC PapersOnLine, 50(1), (pp. 880-885). doi: 10.1016/j.ifacol.2017.08.267

Stewart, K. W., Thomas, F., Pretty, C., Chase, J. G., & Shaw, G. M. (2017). How should we interpret retrospective blood glucose measurements? Sampling and interpolation. IFAC PapersOnLine, 50(1), (pp. 874-879). doi: 10.1016/j.ifacol.2017.08.266

Conference Contribution - Published proceedings: Abstract

Morton, S. E., Dickson, J., Docherty, P., Shaw, G. M., & Chase, J. G. (2017). Development of a predictive model for pulmonary elastance. New Zealand Medical Journal, 130(1459), (pp. 80-81). Retrieved from http://www.nzma.org.nz/journal

Conference Contribution - Verbal presentation and other Conference outputs

Carr, A., Vissers, M., & Shaw, G. (2017, July). Can vitamin C aid immune function in sepsis? Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.

2016

Journal - Research Article

Khan, M., Pretty, C. G., Amies, A. C., Elliott, R., Chiew, Y. S., Shaw, G. M., & Chase, J. G. (2016). Analysing the effects of cold, normal, and warm digits on transmittance pulse oximetry. Biomedical Signal Processing & Control, 26, 34-41. doi: 10.1016/j.bspc.2015.12.006

Stewart, K. W., Pretty, C. G., Tomlinson, H., Thomas, F. L., Homlok, J., Némedi Noémi, S., … Shaw, G. M., … Chase, J. G. (2016). Safety, efficacy and clinical generalization of the STAR protocol: A retrospective analysis. Annals of Intensive Care, 6, 24. doi: 10.1186/s13613-016-0125-9

Kelly, H. E., Shaw, G. M., Brett, C. N., Greenwood, F. M., & Huckabee, M. L. (2016). The effect of titrated fentanyl on suppressed cough reflex in healthy adult volunteers. Anaesthesia, 71, 529-534. doi: 10.1111/anae.13410

Lindsay, A., Bernard, A., Davidson, S. M., Redmond, D. P., Chiew, Y. S., Pretty, C., … Shaw, G. M., Gieseg, S. P., & Draper, N. (2016). Lung injury and respiratory mechanics in rugby union. Journal of Sports Medicine & Physical Fitness, 56(4), 450-457.

Other Research Output

Shaw, G. (2016, April). Engineering customised care at the bedside for better patient outcomes. Public Health Lecture Series, University of Otago, Christchurch, New Zealand. [Public Seminar].

2015

Journal - Research Article

Chiew, Y. S., Pretty, C., Docherty, P. D., Lambermont, B., Shaw, G. M., Desaive, T., & Chase, J. G. (2015). Time-varying respiratory system elastance: A physiological model for patients who are spontaneously breathing. PLoS ONE, 10(1), e0114847. doi: 10.1371/journal.pone.0114847

Carr, A. C., Shaw, G. M., Fowler, A. A., & Natarajan, R. (2015). Ascorbate-dependent vasopressor synthesis: A rationale for vitamin C administration in severe sepsis and septic shock? Critical Care, 19, 418. doi: 10.1186/s13054-015-1131-2

Young, P., Saxena, M., Bellomo, R., Freebairn, R., Hammond, N., van Haren, F., … Henderson, S., … Weatherall, M., … Beasley, R., for the HEAT Investigators, and the Australian and New Zealand Intensive Care Society Clinical Trials Group, including Shaw, G., Bailey, M., & Psirides, A. (2015). Acetaminophen for fever in critically ill patients with suspected infection. New England Journal of Medicine, 373, 2215-2224. doi: 10.1056/NEJMoa1508375

Stewart, K. W., Pretty, C. G., Tomlinson, H., Fisk, L., Shaw, G. M., & Chase, J. G. (2015). Stochastic Model Predictive (STOMP) glycaemic control for the intensive care unit: Development and virtual trial validation. Biomedical Signal Processing & Control, 16, 61-67. doi: 10.1016/j.bspc.2014.09.011

Penning, S., Pretty, C., Preiser, J.-C., Shaw, G. M., Desaive, T., & Chase, J. G. (2015). Glucose control positively influences patient outcome: A retrospective study. Journal of Critical Care, 30, 455-459. doi: 10.1016/j.jcrc.2014.12.013

Conference Contribution - Published proceedings: Full paper

Lau Young, J. B., Rodgers, G. W., Shaw, G. M., & Chase, J. G. (2015). Preliminary studies into acoustic sensing of lung recruitment during mechanical ventilation. IFAC PapersOnLine, 48(20), (pp. 141-146). doi: 10.1016/j.ifacol.2015.10.129

Conference Contribution - Published proceedings: Abstract

Stewart, K. W., Tomlinson, H., Pretty, C., Fisk, L., Thomas, F., Shaw, G. M., … Chase, J. G. (2015). Clinical glycaemic performance of the STAR protocol. New Zealand Medical Journal, 128(1421). Retrieved from https://www.nzma.org.nz/journal

2014

Journal - Research Article

Ralib, A. M., Pickering, J. W., Shaw, G. M., Than, M. P., George, P. M., & Endre, Z. H. (2014). The clinical utility window for acute kidney injury biomarkers in the critically ill. Critical Care, 18, 601. doi: 10.1186/s13054-014-0601-2

Redmond, D., Chiew, Y. S., van Drunen, E., Shaw, G. M., & Chase, J. G. (2014). A minimal algorithm for a minimal recruitment model—model estimation of alveoli opening pressure of an acute respiratory distress syndrome (ARDS) lung. Biomedical Signal Processing & Control, 14, 1-8. doi: 10.1016/j.bspc.2014.05.006

Kamoi, S., Pretty, C., Docherty, P., Squire, D., Revie, J., Chiew, Y. S., … Shaw, G. M., & Chase, J. G. (2014). Continuous stroke volume estimation from aortic pressure using zero dimensional cardiovascular model: Proof of concept study from porcine experiments. PLoS ONE, 9(7), e102476. doi: 10.1371/journal.pone.0102476

Szlavecz, A., Chiew, Y. S., Redmond, D., Beatson, A., Glassenbury, D., Corbett, S., … Shaw, G. M., … Chase, J. G. (2014). The Clinical Utilisation of Respiratory Elastance Software (CURE Soft): A bedside software for real-time respiratory mechanics monitoring and mechanical ventilation management. BioMedical Engineering OnLine, 13, 140. doi: 10.1186/1475-925X-13-140

Sah Pri, A., Chase, J. G., Pretty, C. G., Shaw, G. M., Preiser, J.-C., Vincent, J.-L., … Desaive, T. (2014). Evolution of insulin sensitivity and its variability in out-of-hospital cardiac arrest (OHCA) patients treated with hypothermia. Critical Care, 18, 586. doi: 10.1186/s13054-014-0586-x

Thomas, F., Signal, M., Harris, D. L., Weston, P. J., Harding, J. E., Shaw, G. M., … on behalf of the CHYLD Study Group. (2014). Continuous glucose monitoring in newborn infants: How do errors in calibration measurements affect detected hypoglycemia? Journal of Diabetes Science & Technology, 8(3), 543-550. doi: 10.1177/1932296814524857

van Drunen, E. J., Chiew, Y. S., Pretty, C., Shaw, G. M., Lambermont, B., Janssen, N., … Desaive, T. (2014). Visualisation of time-varying respiratory system elastance in experimental ARDS animal models. BMC Pulmonary Medicine, 14, 33. doi: 10.1186/1471-2466-14-33

Pretty, C. G., Signal, M., Fisk, L., Penning, S., Le Compte, A., Shaw, G. M., … Chase, J. G. (2014). Impact of sensor and measurement timing errors on model-based insulin sensitivity. Computer Methods & Programs in Biomedicine, 114(3), e79-e86. doi: 10.1016/j.cmpb.2013.08.007

Pretty, C. G., Le Compte, A., Penning, S., Fisk, L., Shaw, G. M., Desaive, T., & Chase, J. G. (2014). Interstitial insulin kinetic parameters for a 2-compartment insulin model with saturable clearance. Computer Methods & Programs in Biomedicine, 114(3), e39-e45. doi: 10.1016/j.cmpb.2014.01.011

Thomas, F., Pretty, C. G., Fisk, L., Shaw, G. M., Chase, J. G., & Desaive, T. (2014). Reducing the impact of insulin sensitivity variability on glycaemic outcomes using separate stochastic models within the STAR glycaemic protocol. BioMedical Engineering OnLine, 13, 43. doi: 10.1186/1475-925X-13-43

Journal - Research Other

Shaw, G. M., Pretty, C. G., & Chase, J. G. (2014). Comment on Kalfon et al.: Tight computerized versus conventional glucose control in the ICU: A randomised controlled trial. Intensive Care Medicine, 40(6), 922. doi: 10.1007/s00134-014-3302-z

Chase, J. G., Moeller, K., Shaw, G. M., Schranz, C., Chiew, Y. S., & Desaive, T. (2014). When the value of gold is zero. BMC Research Notes, 7, 404. doi: 10.1186/1756-0500-7-404

Conference Contribution - Published proceedings: Full paper

Guo, P., Clark, A., Chiew, Y. S., Shaw, G. M., Shao, L., & Chase, J. G. (2014). Novel visualisation approach for intensive care unit clinical activity monitoring. Proceedings of the 9th Conference on Industrial Electronics and Applications (ICIEA). (pp. 83-88). IEEE. doi: 10.1109/ICIEA.2014.6931136

Fisk, L. M., Docherty, P. D., Pretty, C. G., Dickson, J. L., Shaw, G. M., & Chase, J. G. (2014). Virtual trials with b-spline basis functions and stochastic differential equations. IFAC Proceedings Volumes, 47(3), (pp. 10976-10981). doi: 10.3182/20140824-6-ZA-1003.01199

Signal, M., Fisk, L., Shaw, G. M., & Chase, J. G. (2014). A pilot study of continuous glucose monitoring in critically ill patients: Do they perform well enough for use in glycaemic control? IFAC Proceedings Volumes, 47(3), (pp. 10970-10975). doi: 10.3182/20140824-6-ZA-1003.00293

Sah Pri, A., Chase, J. G., Pretty, C. G., Shaw, G. M., Preiser, J.-C., Taccone, F., … Desaive, T. (2014). Insulin sensitivity variability during hypothermia. IFAC Proceedings Volumes, 47(3), (pp. 10162-10167). doi: 10.3182/20140824-6-ZA-1003.01090

Dickson, J., Lynn, A., Gunn, C., Le Compte, A., Fisk, L., Shaw, G., & Chase, J. G. (2014). Performance and safety of STAR glycaemic control in neonatal intensive care: Further clinical results including pilot results from a new protocol implementation. IFAC Proceedings Volumes, 47(3), (pp. 10150-10155). doi: 10.3182/20140824-6-ZA-1003.00210

Thomas, F., Tomlinson, H., Watson, A., Borowczyk, H., Pretty, C., Fisk, L., … Shaw, G., & Chase, J. G. (2014). mAGiC DRAGONS: A protocol for accurate glycaemic control in general wards. IFAC Proceedings Volumes, 47(3), (pp. 10138-10143). doi: 10.3182/20140824-6-ZA-1003.01332

Davidson, S. M., Redmond, D. P., Laing, H., White, R., Radzi, F., Chiew, Y. S., … Shaw, G. M., & Chase, J. G. (2014). Clinical Utilisation of Respiratory Elastance (CURE): Pilot trials for the optimisation of mechanical ventilation settings for the critically ill. IFAC Proceedings Volumes, 47(3), (pp. 8403-8408). doi: 10.3182/20140824-6-ZA-1003.01862

Chiew, Y. S., Poole, S. F., Redmond, D. P., van Drunen, E. J., Damanhuri, N. S., Pretty, C., … Shaw, G. M., … Chase, J. G. (2014). Time-varying respiratory elastance for spontaneously breathting patients. IFAC Proceedings Volumes, 47(3), (pp. 5659-5664). doi: 10.3182/20140824-6-ZA-1003.00246

Kamoi, S., Squire, D., Revie, J., Pretty, C., Docherty, P., Chiew, Y. S., … Shaw, G. M., & Chase, J. G. (2014). Accuracy of stroke volume estimation via reservoir pressure concept and three element windkessel model. IFAC Proceedings Volumes, 47(3), (pp. 5647-5652). doi: 10.3182/20140824-6-ZA-1003.01104

Poole, S. F., Chiew, Y. S., Redmond, D. P., Davidson, S. M., Damanhuri, N. S., Pretty, C., … Shaw, G. M., & Chase, J. G. (2014). Real-time breath-to-breath asynchrony event detection using time-varying respiratory elastance model. IFAC Proceedings Volumes, 47(3), (pp. 5629-5634). doi: 10.3182/20140824-6-ZA-1003.00228

Redmond, D. P., Davidson, S. M., Laing, H. A., White, R. H., Radzi, F., Chiew, Y. S., … Shaw, G. M., & Chase, J. G. (2014). Managing patient-specific mechanical ventilation: Clinical utilisation of respiratory elastance (CURE) model and software development. IFAC Proceedings Volumes, 47(3), (pp. 3875-3880). doi: 10.3182/20140824-6-ZA-1003.01109

Conference Contribution - Published proceedings: Abstract

Major, V., Corbett, S., Beatson, A., Glassenbury, D., Redmond, D., Szlávecz, Á., … Shaw, G., & Chase, J. G. (2014). A pressure reconstruction method to estimate respiratory mechanics of breathing masked by spontaneous breathing efforts. New Zealand Medical Journal, 127(1396). Retrieved from http://www.nzma.org.nz/journal

2013

Chapter in Book - Research

Chase, J. G., Benyo, B., Desaive, T., Fisk, L., Dickson, J. L., Penning, S., … Shaw, G. M. (2013). Uncertainty, safety, and performance: A generalizable approach to risk- based (therapeutic) decision making. In A. Agah (Ed.), Medical applications of artificial intelligence. (pp. 233-246). Boca Raton, FL: CRC Press.

Journal - Research Article

Chiew, Y. S., Chase, J. G., Lambermont, B., Janssen, N., Schranz, C., Moeller, K., Shaw, G. M., & Desaive, T. (2013). Physiological relevance and performance of a minimal lung model: An experimental study in healthy and acute respiratory distress syndrome model piglets. BMC Pulmonary Medicine, 12, 59. doi: 10.1186/1471-2466-12-59

Desaive, T., Lambermont, B., Janssen, N., Ghuysen, A., Kolh, P., Morimont, P., … Shaw, G. M., & Chase, J. G. (2013). Assessment of ventricular contractility and ventricular-arterial coupling with a model-based sensor. Computer Methods & Programs in Biomedicine, 109(2), 182-189. doi: 10.1016/j.cmpb.2011.11.009

Dickson, J. L., Le Compte, A. J., Floyd, R. P., Chase, J. G., Lynn, A., & Shaw, G. M. (2013). Development and optimisation of stochastic targeted (STAR) glyceamic control for pre-term infants in neonatal intensive care. Biomedical Signal Processing & Control, 8(2), 215-221.

Dickson, J. L., Floyd, R. P., Le Compte, A. J., Fisk, L. M., Chase, J. G., Lynn, A., & Shaw, G. M. (2013). External validation and sub-cohort analysis of stochastic forecasting models in NICU cohorts. Biomedical Signal Processing & Control, 8(4), 409-419. doi: 10.1016/j.bspc.2013.01.006

van Drunen, E. J., Chase, J. G., Chiew, Y. S., Shaw, G. M., & Desaive, T. (2013). Analysis of different model-based approaches for estimating dFRC for real-time application. BioMedical Engineering OnLine, 12, 9. doi: 10.1186/1475-925X-12-9

Revie, J. A., Stevenson, D., Chase, J. G., Pretty, C. J., Lambermont, B. C., Ghuysen, A., … Shaw, G. M., & Desaive, T. (2013). Evaluation of a model-based hemodynamic monitoring method in a porcine study of septic shock. Computational & Mathematical Methods in Medicine, 2013, 505417. doi: 10.1155/2013/505417

Gunn, C. A., Dickson, J. L., Hewett, J. N., Lynn, A., Rose, H. J., Shaw, G. M., … Chase, J. G. (2013). Nasogastric aspiration as an indicator for feed absorption in model-based glycemic control in neonatal intensive care. Journal of Diabetes Science & Technology, 7(3), 717-726. doi: 10.1177/193229681300700317

van Drunen, E. J., Chiew, Y. S., Chase, J. G., Shaw, G. M., Lambermont, B., Janssen, N., … Desaive, T. (2013). Expiratory model-based method to monitor ARDS disease state. BioMedical Engineering OnLine, 12, 57. doi: 10.1186/1475-925X-12-57

Dickson, J. L., Hewett, J. N., Gunn, C. A., Lynn, A., Shaw, G. M., & Chase, J. G. (2013). On the problem of patient-specific endogenous glucose production in neonates on stochastic targeted glycemic control. Journal of Diabetes Science & Technology, 7(4), 913-927. doi: 10.1177/193229681300700414

Signal, M., Thomas, F., Shaw, G. M., & Chase, J. G. (2013). Complexity of continuous glucose monitoring data in critically ill patients: Continuous glucose monitoring devices, sensor locations, and detrended fluctuation analysis methods. Journal of Diabetes Science & Technology, 7(6), 1492-1506. doi: 10.1177/193229681300700609

Md Ralib, A., Pickering, J. W., Shaw, G. M., & Endre, Z. H. (2013). The urine output definition of acute kidney injury is too liberal. Critical Care, 17, R112. doi: 10.1186/cc12784

Ralib, A. M., Pickering, J. W., Major, T., Palmer, S. C., Shaw, G. M., Goodkin, D. A., & Endre, Z. H. (2013). High-dose intravenous epoetin does not increase blood pressure in critically ill patients with acute kidney injury. Clinical Nephrology, 79(5), 370-379. doi: 10.5414/cn107673

Ferenci, T., Benyó, B., Kovács, L., Fisk, L., Shaw, G. M., & Chase, J. G. (2013). Daily evolution of insulin sensitivity variability with respect to diagnosis in the critically ill. PLoS ONE, 8(2), e57119. doi: 10.1371/journal.pone.0057119

Docherty, P. D., Berkeley, J. E., Lotz, T. F., Te Morenga, L., Fisk, L. M., Shaw, G. M., McAuley, K. A., Mann, J. I., & Chase, J. G. (2013). Clinical validation of the quick dynamic insulin sensitivity test. IEEE Transactions on Biomedical Engineering, 60(5), 1266-1272. doi: 10.1109/TBME.2012.2232667

Willis, J. G., Fisk, L., Razak, N., Le Compte, A., Shaw, G. M., & Chase, J. G. (2013). Insulin Glargine in the intensive care unit: A model-based clinical trial design. Biomedical Signal Processing & Control, 8(2), 120-129. doi: 10.1016/j.bspc.2012.09.004

Revie, J. A., Stevenson, D. J., Chase, J. G., Hann, C. E., Lambermont, B. C., Ghuysen, A., … Shaw, G. M., … Desaive, T. (2013). Validation of subject-specific cardiovascular system models from porcine measurements. Computer Methods & Programs in Biomedicine, 109(2), 197-210. doi: 10.1016/j.cmpb.2011.10.013

Le Compte, A. J., Pretty, C. G., Lin, J., Shaw, G. M., Lynn, A., & Chase, J. G. (2013). Impact of variation in patient response on model-based control of glycaemia in critically ill patients. Computer Methods & Programs in Biomedicine, 109(2), 211-219. doi: 10.1016/j.cmpb.2011.08.007

Journal - Research Other

Signal, M., Fisk, L., Shaw, G. M., & Chase, J. G. (2013). Concurrent continuous glucose monitoring in critically ill patients: Interim results and observations. Journal of Diabetes Science & Technology, 7(6), 1652-1653. doi: 10.1177/193229681300700629

Conference Contribution - Published proceedings: Full paper

Razak, N. N., Chase, J. G., Suhaimi, F. M., Shaw, G. M., & Jamaluddin, U. (2013). A model-based control protocol for transition from ICU to HDU: Robustness analysis. Proceedings of the Engineering in Medicine and Biology Society (EMBC) 35th Annual International Conference. (pp. 205-208). IEEE. doi: 10.1109/EMBC.2013.6609473

Sturney, S. C., Storer, M. K., Shaw, G. M., Shaw, D. E., & Epton, M. J. (2013). Off-line breath acetone analysis in critical illness. Journal of Breath Research, 7(3), 037102. doi: 10.1088/1752-7155/7/3/037102

Jamaludin, U. K., Docherty, P. D., Chase, J. G., & Shaw, G. M. (2013). Impact of haemodialysis on insulin sensitivity of acute renal failure (ARF) patients with sepsis in critical care. Proceedings of the Engineering in Medicine and Biology Society (EMBC) 35th Annual International Conference. (pp. 3503-3506). IEEE. doi: 10.1109/EMBC.2013.6610297

Conference Contribution - Published proceedings: Abstract

Sturney, S. C., Storer, M. K., Shaw, G. M., Kennedy, R. R., Shaw, D. E., & Epton, M. J. (2013). An off-line end-tidal breath sampling method in anaesthetised patients with analysis by selected ion flow tube mass spectrometry. Thorax, 68(Suppl. 3), (pp. A158). doi: 10.1136/thoraxjnl-2013-204457.335

Lindsay, A. J. C., Shaw, G. M., Scarrott, C. J., Lewis, J. G., Gieseg, S. P., & Draper, N. (2013). The effect of acute exercise on levels of stress in rugby union and competitive body-building. Proceedings of the Sport and Exercise Science New Zealand (SESNZ) Annual Conference: Exercise Science for Health and Sport Performance. (pp. 58-59). Retrieved from http://www.sesnz.org.nz/Conference/

Redmond, D., Davidson, S., Laing, H., White, R., Radzi, F., Wang, N., … Shaw, G. M., & Chase, J. G. (2013). Are you managing your mechanical ventilator correctly? A model-based answer to an on-going question. New Zealand Medical Journal, 126(1375). Retrieved from http://www.nzma.org.nz/journal

Chiew, Y. S., van Drunen, E. J., Lambermont, B., Morimont, P., Janssen, N., Pretty, C., … Shaw, G. M., & Chase, J. G. (2013). In-breath monitoring of lung recruitment and distension using pulmonary mechanics in an experimental ARDS animal model. Intensive Care Medicine, 39(Suppl. 2), (pp. S496-S497). doi: 10.1007/s00134-013-3095-5

Taccone, F. S., Preiser, J.-C., Sah Pri, A., Shaw, G. M., Chase, G., & Desaive, T. (2013). Insulin sensitivity in out of hospital cardiac arrest patients treated with hypothermia. Intensive Care Medicine, 39(Suppl. 2), (pp. S289). doi: 10.1007/s00134-013-3095-5

Chiew, Y. S., van Drunen, E. J., Poole, S., Lambermont, B., Morimont, P., Damanhuri, N. S., … Shaw, G. M., … Chase, J. G. (2013). Patient-ventilator interaction using time-varying pulmonary mechanics: A retrospective comparison between pressure support and neurally adjusted ventilatory assist. Intensive Care Medicine, 39(Suppl. 2), (pp. S250). doi: 10.1007/s00134-013-3095-5

Md Ralib, A., Pickering, J. W., Shaw, G. M., & Endre, Z. H. (2013). Urine output criteria in prediction of mortality or dialysis requirements in the critically ill. Proceedings of the World Congress of Nephrology. Retrieved from http://www.theisn.org/

Md Ralib, A., Pickering, J. W., Shaw, G. M., Than, M., & Endre, Z. H. (2013). Earlier measurement of biomarkers does not enhance detection of acute kidney injury following significant kidney hypoperfusion. Proceedings of the World Congress of Nephrology. Retrieved from http://www.theisn.org/

Md Ralib, A., Pickering, J. W., Shaw, G. M., Than, M., & Endre, Z. H. (2013). The impact of fluid overload on mortality and acute kidney injury. Proceedings of the World Congress of Nephrology. Retrieved from http://www.theisn.org/

Thomas, F., Signal, M., Shaw, G. M., & Chase, J. G. (2013). Can this cool new glycaemia metric tell me if my critical care patients are going to live or die? New Zealand Medical Journal, 126(1375). Retrieved from http://www.nzma.org.nz/journal

Fisk, L. M., Chase, J. G., Le Compte, A. J., & Shaw, G. M. (2013). Glycaemic control through stochastic forecasting: Implementing STAR as the standard of care in Christchurch Hospital ICU. New Zealand Medical Journal, 126(1375). Retrieved from http://www.nzma.org.nz/journal

Revie, J. A., Stevenson, D. J., Chase, J. G., Lambermont, B. C., Ghuysen, A., Kolh, P., Shaw, G. M., & Desaive, T. (2013). Aortic flow energetics in a porcine study of septic shock. New Zealand Medical Journal, 126(1375). Retrieved from http://www.nzma.org.nz/journal

Conference Contribution - Verbal presentation and other Conference outputs

Chase, G., & Shaw, G. (2013, December). Model-based therapeutics and critical care: Models and medicine for better clinical outcomes. Verbal presentation at the MedTech in Christchurch Workshop, Christchurch, New Zealand.

2012

Journal - Research Article

Ward, L., Steel, J., Le Compte, A., Evans, A., Tan, C.-S., Penning, S., Shaw, G. M., … Chase, J. G. (2012). Data entry errors and design for model-based tight glycemic control in critical care. Journal of Diabetes Science & Technology, 6(1), 135-143. doi: 10.1177/193229681200600116

Ward, L., Steel, J., Le Compte, A., Evans, A., Tan, C.-S., Penning, S., Shaw, G. M., … Chase, J. G. (2012). Interface design and human factors considerations for model-based tight glycemic control in critical care. Journal of Diabetes Science & Technology, 6(1), 125-134. doi: 10.1177/193229681200600115

Evans, A., Le Compte, A., Tan, C.-S., Ward, L., Steel, J., Pretty, C. G., … Shaw, G. M., … Chase, J. G. (2012). Stochastic targeted (STAR) glycemic control: Design, safety, and performance. Journal of Diabetes Science & Technology, 6(1), 102-115. doi: 10.1177/193229681200600113

Pretty, C. G., Le Compte, A. J., Chase, J. G., Shaw, G. M., Preiser, J.-C., Penning, S., & Desaive, T. (2012). Variability of insulin sensitivity during the first 4 days of critical illness: Implications for tight glycemic control. Annals of Intensive Care, 2, 17. doi: 10.1186/2110-5820-2-17

Stevenson, D., Revie, J., Chase, J. G., Hann, C. E., Shaw, G. M., Lambermont, B., … Desaive, T. (2012). Beat-to-beat estimation of the continuous left and right cardiac elastance from metrics commonly available in clinical settings. BioMedical Engineering OnLine, 11, 73. doi: 10.1186/1475-925X-11-73

Fisk, L. M., Le Compte, A. J., Shaw, G. M., Penning, S., Desaive, T., & Chase, J. G. (2012). STAR development and protocol comparison. IEEE Transactions on Biomedical Engineering, 59(12), 3357-3364. doi: 10.1109/TBME.2012.2214384

Benyo, B., Illyés, A., Némedi, N. S., Le Compte, A. J., Havas, A., Kovacs, L., … Shaw, G. M., & Chase, J. G. (2012). Pilot study of the SPRINT glycemic control protocol in a Hungarian medical intensive care unit. Journal of Diabetes Science & Technology, 6(6), 1464-1477. doi: 10.1177/193229681200600628

Penning, S., Le Compte, A. J., Massion, P., Moorhead, K. T., Pretty, C. G., Preiser, J.-C., Shaw, G. M., … Chase, J. G. (2012). Second pilot trials of the STAR-Liege protocol for tight glycemic control in critically ill patients. BioMedical Engineering OnLine, 11, 58. doi: 10.1186/1475-925x-11-58

Le Compte, A. J., Lynn, A. M., Lin, J., Pretty, C. G., Shaw, G. M., & Chase, J. G. (2012). Pilot study of a model-based approach to blood glucose control in very-low-birthweight neonates. BMC Pediatrics, 12, 117. doi: 10.1186/1471-2431-12-117

Fisk, L. M., Le Compte, A. J., Shaw, G. M., & Chase, J. G. (2012). Improving safety of glucose control in intensive care using virtual patients and simulated clinical trials. Journal of Healthcare Engineering, 3(3), 415-430. doi: 10.1260/2040-2295.3.3.415

Pickering, J. W., Frampton, C. M., Walker, R. J., Shaw, G. M., & Endre, Z. H. (2012). Four hour creatinine clearance is better than plasma creatinine for monitoring renal function in critically ill patients. Critical Care, 16, R107. doi: 10.1186/cc11391

Jamaludin, U. K., Docherty, P. D., Chase, J. G., Le Compte, A., Shaw, G. M., Desaive, T., & Preiser, J.-C. (2012). Observation of incretin effects during enteral feed transitions of critically ill patients. e-SPEN Journal, 7(4), e154-e159. doi: 10.1016/j.clnme.2012.05.002

Penning, S., Le Compte, A. J., Moorhead, K. T., Desaive, T., Massion, P., Preiser, J.-C., Shaw, G. M., & Chase, J. G. (2012). First pilot trial of the STAR-Liege protocol for tight glycemic control in critically ill patients. Computer Methods & Programs in Biomedicine, 108(2), 844-859. doi: 10.1016/j.cmpb.2011.07.003

Md Ralib, A., Pickering, J. W., Shaw, G. M., Devarajan, P., Edelstein, C. L., Bonventre, J. V., & Endre, Z. H. (2012). Test characteristics of urinary biomarkers depend on quantitation method in acute kidney injury. Journal of the American Society of Nephrology, 23(2), 322-333. doi: 10.1681/asn.2011040325

Journal - Research Other

Shaw, G. M., & Chase, J. G. (2012). Does "treatment failure bias" impact comparisons of ICUs? Intensive Care Medicine, 38(8), 1412. doi: 10.1007/s00134-012-2562-8

Chase, J. G., & Shaw, G. M. (2012). How standard is the "S" in SMR? Intensive Care Medicine, 38, 1-3. doi: 10.1007/s00134-011-2392-0

Conference Contribution - Published proceedings: Full paper

Suhaimi, F. M., Chase, J. G., Le Compte, A. J., Pretty, C. G., Elliott, R., Wenz, A., Shaw, G. M., & Abdul Razak, N. (2012). Assessing microcirculation condition in critical illness using the pulse oximeter's concept. Proceedings of the Biomedical Engineering and Sciences (IECBES) Conference. (pp. 939-943). IEEE. doi: 10.1109/IECBES.2012.6498030

Signal, M., Le Compte, A., Shaw, G. M., & Chase, J. G. (2012). Glycemic levels in critically ill patients: Are normoglycemia and low variability associated with improved outcomes? Journal of Diabetes Science & Technology, 6(5), (pp. 1030-1037). doi: 10.1177/193229681200600506

Stevenson, D., Revie, J. A., Chase, J. G., Shaw, G. M., Lambermont, B., Ghuysen, A., … Desaive, T. (2012). Estimating afterload, systemic vascular resistance and pulmonary vascular resistance in an intensive care setting. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 501-506). doi: 10.3182/20120829-3-HU-2029.00112

Hewett, J., Rodgers, G. W., Chase, J. G., Le Compte, A., Pretty, C., & Shaw, G. M. (2012). Assessment of SOFA score as a diagnostic indicator in intensive care medicine. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 467-472). doi: 10.3182/20120829-3-HU-2029.00035

Ferenci, T., Kovacs, L., Benyo, B., Le Compte, A., Shaw, G. M., & Chase, J. G. (2012). Effect of diagnosis on variability of ICU patients in insulin sensitivity. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 462-466). doi: 10.3182/20120829-3-HU-2029.00108

Chiew, Y. S., Desaive, T., Lambermont, B., Janssen, N., Shaw, G. M., Schranz, C., … Chase, J. G. (2012). Physiological relevance of a minimal model in healthy pigs lung. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 444-449). doi: 10.3182/20120829-3-HU-2029.00017

Revie, J. A., Stevenson, D., Chase, J. G., Lambermont, B., Ghuysen, A., Kolh, P., Shaw, G. M., & Desaive, T. (2012). Analysis of aortic energetics from pulse wave examination in a porcine study of septic shock. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 438-443). doi: 10.3182/20120829-3-HU-2029.00014

Revie, J. A., Stevenson, D., Chase, J. G., Lambermont, B., Ghuysen, A., Kolh, P., Shaw, G. M., & Desaive, T. (2012). Model-based monitoring of septic shock treated with large-pore hemofiltration therapy. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 432-437). doi: 10.3182/20120829-3-HU-2029.00013

Jamaludin, U. K., Docherty, P. D., Chase, J. G., Le Compte, A., & Shaw, G. M. (2012). Observation of changes in model-based insulin sensitivity during haemodialysis transitions for critically ill patients. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 349-354). doi: 10.3182/20120829-3-HU-2029.00021

Fisk, L., Le Compte, A., Shaw, G. M., Penning, S., Desaive, T., & Chase, J. G. (2012). Development and pilot trial results of stochastic targeted (STAR) glycemic control in a medical ICU. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 301-306). doi: 10.3182/20120829-3-HU-2029.00044

Floyd, R. P., Dickson, J. L., Le Compte, A., Chase, J. G., Lynn, A., & Shaw, G. M. (2012). External validation and sub-cohort analysis of stochastic forecasting models in NICU cohorts. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 313-318). doi: 10.3182/20120829-3-HU-2029.00110

Fisk, L., Clarkson, S., Le Compte, A., Shaw, G. M., & Chase, J. G. (2012). Nutrition rates and impact of clinical stoppages to two AGC protocols. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 307-312). doi: 10.3182/20120829-3-HU-2029.00060

Fisk, L., Willis, J., Le Compte, A., Shaw, G. M., & Chase, J. G. (2012). Glargine and glycemia: Pitfalls and perils. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 254-259). doi: 10.3182/20120829-3-HU-2029.00063

Dickson, J. L., Le Compte, A., Floyd, R. P., Chase, J. G., Lynn, A., & Shaw, G. M. (2012). Development and optimisation of stochastic targeted (STAR) glycaemic control for neonatal intensive care. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 319-324). doi: 10.3182/20120829-3-HU-2029.00034

Pretty, C., Le Compte, A., Shaw, G. M., & Chase, J. G. (2012). Interstitial insulin kinetic parameters for a 2-compartment insulin model with saturable clearance. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 230-235). doi: 10.3182/20120829-3-HU-2029.00020

Pretty, C., Le Compte, A., Shaw, G. M., & Chase, J. G. (2012). Impact of sensor and measurement timing errors on model-based insulin sensitivity. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 224-229). doi: 10.3182/20120829-3-HU-2029.00019

Mishra, A., Chiew, Y. S., Shaw, G. M., & Chase, J. G. (2012). Model-based approach to estimate Dfrc in the ICU using measured lung dynamics. In B. Benyo, S. Andreassen, D. D. Feng, E. Carson, J. G. Chase & L. Kovács (Eds.), Proceedings of the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems. 8(Pt. 1), (pp. 143-148). doi: 10.3182/20120829-3-HU-2029.00027

Conference Contribution - Published proceedings: Abstract

Revie, J. A., Stevenson, D. J., Chase, J. G., Lambermont, B. C., Ghuysen, A., Kolh, P., Shaw, G. M., & Desaive, T. (2012). Computer-based monitoring of global cardiovascular dynamics during acute pulmonary embolism and septic shock in swine. Critical Care, 16(Suppl. 1), (pp. S82). doi: 10.1186/cc10835

Penning, S., Le Compte, A. J., Signal, M., Massion, P., Preiser, J. C., Shaw, G. M., … Chase, J. G. (2012). Does tight glycemic control positively impact on patient mortality? Critical Care, 16(Suppl. 1), (pp. S63). doi: 10.1186/cc10783

Le Compte, A. J., Pretty, C. G., Shaw, G. M., & Chase, J. G. (2012). Glucometer accuracy and implications for clinical studies. Critical Care, 16(Suppl. 1), (pp. S61-S62). doi: 10.1186/cc10780

Fisk, L. M., Le Compte, A. J., Shaw, G. M., Penning, S., Desaive, T., & Chase, J. G. (2012). Pilot trial of STAR in the medical ICU. Critical Care, 16(Suppl. 1), (pp. S61). doi: 10.1186/cc10779

Pretty, C., Le Compte, A., Lin, J., Shaw, G., & Chase, J. G. (2012). Endogenous insulin secretion in critically ill patients. Critical Care, 16(Suppl. 1), (pp. S60). doi: 10.1186/cc10775

Pretty, C., Le Compte, A., Chase, J. G., Shaw, G., Preiser, J. C., Penning, S., & Desaive, T. (2012). Variability of insulin sensitivity during the first 4 days of critical illness. Critical Care, 16(Suppl. 1), (pp. S59-S60). doi: 10.1186/cc10774

Chiew, Y. S., Chase, J. G., Shaw, G. M., & Desaive, T. (2012). Respiratory system elastance monitoring during PEEP titration. Critical Care, 16(Suppl. 1), (pp. S37). doi: 10.1186/cc10710

Md Ralib, A., Pickering, J. W., Shaw, G., Than, M., & Endre, Z. H. (2012). Transient Acute Kidney Injury (AKI) is common following significant renal hypoperfusion. Nephrology, 17(Suppl. 2), (pp. 54). doi: 10.1111/j.1440-1797.2012.01632.x

Pickering, J. W., Frampton, C. M., Walker, R. J., Shaw, G. M., & Endre, Z. H. (2012). 4-hour creatinine clearance in the intensive care unit. Nephrology, 17(Suppl. 2), (pp. 45). doi: 10.1111/j.1440-1797.2012.01631.x

Revie, J. A., Stevenson, D. J., Chase, J. G., Hann, C. E., Shaw, G. M., Le Compte, A., … Desaive, T. (2012). Model-based diagnosis of acute plumonary embolism and septic shock in porcine trials. New Zealand Medical Journal, 125(1352). Retrieved from http://www.nzma.org.nz/journal

Conference Contribution - Poster Presentation (not in published proceedings)

Md Ralib, A., Pickering, J., Shaw, G., Than, M., & Endre, Z. (2012, September). Transient acute kidney injury is common following significant renal hypoperfusion. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Desaive, T., Lambermont, B., Kolh, P., Shaw, G. M., & Chase, J. G. (2012, August). Cardiovascular modelling and the intensive care unit clinician. Keynote presentation at the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems, Budapest, Hungary.

Le Compte, A., Shaw, G. M., & Chase, J. G. (2012, August). Benchtop to bedside to worldwide: Implementing model-based glycemic control in intensive care. Keynote presentation at the 8th International Federation of Automatic Control (IFAC) Symposium on Biological and Medical Systems, Budapest, Hungary.

2011

Journal - Research Article

Docherty, P. D., Chase, J. G., Te Morenga, L., Lotz, T. F., Berkeley, J. E., Shaw, G. M., McAuley, K. A., & Mann, J. I. (2011). A spectrum of dynamic insulin sensitivity test protocols. Journal of Diabetes Science & Technology, 5(6), 1499-1508.

Chase, J. G., Lambermont, B., Starfinger, C., Hann, C. E., Shaw, G. M., Ghuysen, A., … Desaive, T. (2011). Subject-specific cardiovascular system model-based identification and diagnosis of septic shock with a minimally invasive data set: Animal experiments and proof of concept. Physiological Measurement, 32(1), 65-82. doi: 10.1088/0967-3334/32/1/005

Hann, C. E., Revie, J., Stevenson, D., Heldmann, S., Desaive, T., Froissart, C. B., … Shaw, G. M., & Chase, J. G. (2011). Patient specific identification of the cardiac driver function in a cardiovascular system model. Computer Methods & Programs in Biomedicine, 101(2), 201-207. doi: 10.1016/j.cmpb.2010.06.005

Sundaresan, A., Chase, J. G., Shaw, G. M., Chiew, Y. S., & Desaive, T. (2011). Model-based optimal PEEP in mechanically ventilated ARDS patients in the Intensive Care Unit. BioMedical Engineering OnLine, 10, 64. doi: 10.1186/1475-925x-10-64

Sundaresan, A., Chase, J. G., Hann, C. E., & Shaw, G. M. (2011). Dynamic functional residual capacity can be estimated using a stress-strain approach. Computer Methods & Programs in Biomedicine, 101(2), 135-143. doi: 10.1016/j.cmpb.2010.05.005

McAuley, K. A., Berkeley, J. E., Docherty, P. D., Lotz, T. F., Te Morenga, L. A., Shaw, G. M., Williams, S. M., … Mann, J. I. (2011). The dynamic insulin sensitivity and secretion test: A novel measure of insulin sensitivity. Metabolism, 60(12), 1748-1756. doi: 10.1016/j.metabol.2011.05.009

Le Compte, A. J., Chase, J. G., Lynn, A., Hann, C. E., Shaw, G. M., & Lin, J. (2011). Development of blood glucose control for extremely premature infants. Computer Methods & Programs in Biomedicine, 102(2), 181-191. doi: 10.1016/j.cmpb.2010.03.010

Pretty, C., Chase, J. G., Lin, J., Shaw, G. M., Le Compte, A., Razak, N., & Parente, J. D. (2011). Impact of glucocorticoids on insulin resistance in the critically ill. Computer Methods & Programs in Biomedicine, 102(2), 172-180. doi: 10.1016/j.cmpb.2010.08.004

Endre, Z. H., Pickering, J. W., Walker, R. J., Devarajan, P., Edelstein, C. L., Bonventre, J. V., Frampton, C. M., … Shaw, G. M., Henderson, S. J., Nejat, M., Schollum, J. B. W., & George, P. M. (2011). Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney International, 79, 1119-1130. doi: 10.1038/ki.2010.555

Lin, J., Razak, N. N., Pretty, C. G., Le Compte, A., Docherty, P., Parente, J. D., Shaw, G. M., … Chase, J. G. (2011). A physiological Intensive Control Insulin-Nutrition-Glucose (ICING) model validated in critically ill patients. Computer Methods & Programs in Biomedicine, 102(2), 192-205. doi: 10.1016/j.cmpb.2010.12.008

Chase, J. G., Le Compte, A. J., Suhaimi, F., Shaw, G. M., Lynn, A., Lin, J., … Desaive, T. (2011). Tight glycemic control in critical care: The leading role of insulin sensitivity and patient variability: A review and model-based analysis. Computer Methods & Programs in Biomedicine, 102(2), 156-171. doi: 10.1016/j.cmpb.2010.11.006

Docherty, P. D., Chase, J. G., Lotz, T. F., Hann, C. E., Shaw, G. M., Berkeley, J. E., Te Morenga, L., Mann, J. I., & McAuley, K. (2011). Independent cohort cross-validation of the real-time DISTq estimation of insulin sensitivity. Computer Methods & Programs in Biomedicine, 102(2), 94-104. doi: 10.1016/j.cmpb.2010.08.002

Le Compte, A., Chase, J. G., Russell, G., Lynn, A. M., Hann, C., Shaw, G., … Lin, J. (2011). Modeling the glucose regulatory system in extreme preterm infants. Computer Methods & Programs in Biomedicine, 102(3), 253-266. doi: 10.1016/j.cmpb.2010.05.006

Lin, J., Parente, J. D., Chase, J. G., Shaw, G. M., Blakemore, A. J., LeCompte, A. J., … Wang, S.-H. (2011). Development of a model-based clinical sepsis biomarker for critically ill patients. Computer Methods & Programs in Biomedicine, 102(2), 149-155. doi: 10.1016/j.cmpb.2010.04.002

Conference Contribution - Published proceedings: Full paper

Chase, J. G., Le Compte, A. J., Evans, A., Ward, L., Steel, J., Tan, C. S., … Shaw, G. M. (2011). Tight glycemic control in intensive care: From engineering to clinical practice change. IFMBE Proceedings, 37(1, Pt. 2), (pp. 11-14). doi: 10.1007/978-3-642-23508-5_5

Conference Contribution - Published proceedings: Abstract

Pretty, C., Chase, J. G., Le Compte, A., Lin, J., & Shaw, G. M. (2011). Impact of metoprolol on insulin sensitivity in the ICU. Proceedings of the 18th World Congress of the International Federation of Automatic Control (IFAC). doi: 10.3182/20110828-6-IT-1002.01729

Docherty, P. D., Chase, J. G., Lotz, T., Berkeley, J. E., & Shaw, G. M. (2011). An in-silico analysis of the ability of dynamic tests to trace the kinetic behaviour of insulin sensitizer drugs. Proceedings of the 18th World Congress of the International Federation of Automatic Control (IFAC). doi: 10.3182/20110828-6-IT-1002.01687

2010

Journal - Research Article

Chase, J. G., Pretty, C. G., Pfeifer, L. J., Shaw, G. M., Preiser, J.-C., Le Compte, A., Lin, J., … Desaive, T. (2010). Organ failure and tight glycemic control in the SPRINT study. Critical Care, 14, R154. doi: 10.1186/cc9224

Chase, J. G., Suhaimi, F., Penning, S., Preiser, J.-C., Le Compte, A. J., Lin, J., … Shaw, G. M., & Desaive, T. (2010). Validation of a model-based virtual trials method for tight glycemic control in intensive care. BioMedical Engineering OnLine, 9, 84. doi: 10.1186/1475-925x-9-84

Hann, C. E., Chase, J. G., Desaive, T., Froissart, C. B., Revie, J., Lambermont, B., … Shaw, G. M. (2010). Unique parameter identification for cardiac diagnosis in critical care using minimal data sets. Computer Methods & Programs in Biomedicine, 99(1), 75-87. doi: 10.1016/j.cmpb.2010.01.002

Hann, C. E., Docherty, P., Chase, J. G., & Shaw, G. M. (2010). A fast generalizable solution method for glucose control algorithms. Mathematical Biosciences, 227(1), 44-55. doi: 10.1016/j.mbs.2010.06.001

Hann, C. E., Hewett, D., Chase, J. G., Rabczuk, T., Sundaresan, A., Chen, X., … Shaw, G. M. (2010). Image-based measurement of alveoli volume expansion in an animal model of a diseased lung. International Journal of Computer Applications in Technology, 39(1-3), 58-65. doi: 10.1504/ijcat.2010.034731

Le Compte, A. J., Lee, D. S., Chase, J. G., Lin, J., Lynn, A., & Shaw, G. M. (2010). Blood glucose prediction using stochastic modeling in neonatal intensive care. IEEE Transactions on Biomedical Engineering, 57(3), 509-518. doi: 10.1109/tbme.2009.2035517

Pretty, C. G., Chase, J. G., Le Compte, A., Shaw, G. M., & Signal, M. (2010). Hypoglycemia detection in critical care using continuous glucose monitors: An in silico proof of concept analysis. Journal of Diabetes Science & Technology, 4(1), 15-24.

Signal, M., Pretty, C. G., Chase, J. G., Le Compte, A., & Shaw, G. M. (2010). Continuous glucose monitors and the burden of tight glycemic control in critical care: Can they cure the time cost? Journal of Diabetes Science & Technology, 4(3), 625-635.

Suhaimi, F., Le Compte, A., Preiser, J.-C., Shaw, G. M., Massion, P., Radermecker, R., … Chase, J. G. (2010). What makes tight glycemic control tight? The impact of variability and nutrition in two clinical studies. Journal of Diabetes Science & Technology, 4(2), 284-298.

Sundaresan, A., Chase, J. G., Hann, C. E., & Shaw, G. M. (2010). Cardiac output estimation using pulmonary mechanics in mechanically ventilated patients. BioMedical Engineering OnLine, 9, 80. doi: 10.1186/1475-925x-9-80

Lotz, T. F., Chase, J. G., McAuley, K. A., Shaw, G. M., Docherty, P. D., Berkeley, J. E., Williams, S. M., … Mann, J. I. (2010). Design and clinical pilot testing of the model-based dynamic insulin sensitivity and secretion test (DISST). Journal of Diabetes Science & Technology, 4(6), 1408-1423.

Nejat, M., Pickering, J. W., Walker, R. J., Westhuyzen, J., Shaw, G. M., Frampton, C. M., & Endre, Z. H. (2010). Urinary cystatin C is diagnostic of acute kidney injury and sepsis, and predicts mortality in the intensive care unit. Critical Care, 14(3), R85. doi: 10.1186/cc9014

Endre, Z. H., Walker, R. J., Pickering, J. W., Shaw, G. M., Frampton, C. M., Henderson, S. J., Hutchison, R., … Robinson, J. M., Schollum, J. B. W., … Celi, L. A., … George, P. M. (2010). Early intervention with erythropoietin does not affect the outcome of acute kidney injury (the EARLYARF trial). Kidney International, 77, 1020-1030. doi: 10.1038/ki.2010.25

Conference Contribution - Published proceedings: Full paper

Greenfield, K. M., Dove, R. A., Shaw, G. M., & Robinson, G. (2010). Towards improved sedation control in critically ill patients. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS). (pp. 540-543). IEEE. doi: 10.1109/IEMBS.2010.5626030

Conference Contribution - Published proceedings: Abstract

Suhaimi, F., Chase, J. G., Preiser, J. C., Le Compte, A. J., Lin, J., Pretty, C. G., Shaw, G. M., & Desaive, T. (2010). Validation of a virtual trial method for tight glycemic control in intensive care. New Zealand Medical Journal, 123(1324). Retrieved from http://www.nzma.org.nz/journal/123-1324/4402/content.pdf

Lin, J., Razak, N. N., Chase, J. G., Pretty, C. G., Suhaimi, F., Jamaluddin, U., … Shaw, G. M. (2010). A highly predictive metabolic model for glycemic control of critically ill patients. New Zealand Medical Journal, 123(1324). Retrieved from http://www.nzma.org.nz/journal/123-1324/4402/content.pdf

Revie, J., Hann, C. E., Stevenson, D., Chase, J. G., Heldmann, S., Shaw, G. M., … Kolh, A. (2010). Model-based cardiac disease diagnosis in critical care. New Zealand Medical Journal, 123(1313). Retrieved from http://journal.nzma.org.nz/journal/123-1313/4096/content.pdf

Hann, C. E., Revie, J., Hewett, D., Chase, J. G., & Shaw, G. M. (2010). Screening for diabetic retinopathy using computer vision and physiological markers. New Zealand Medical Journal, 123(1312). Retrieved from http://journal.nzma.org.nz/journal/123-1312/4074/content.pdf

Parente, J. D., Lee, D., Lin, J., Chase, J. G., & Shaw, G. M. (2010). An hourly and accurate model-based insulin sensitivity clinical biomarker for sepsis in critical care patients. New Zealand Medical Journal, 123(1312). Retrieved from http://journal.nzma.org.nz/journal/123-1312/4074/content.pdf

Stevenson, D., Hann, C. E., Revie, J., Chase, J. G., Heldmann, S., Shaw, G. M., … Kolh, A. (2010). Patient specific modelling of cardiac muscle activation. New Zealand Medical Journal, 123(1313). Retrieved from http://journal.nzma.org.nz/journal/123-1313/4096/content.pdf

Shaw, G. M., Chase, J. G., & Sundaresan, A. (2010). Demystifying anaesthesia for the critically ill: New concepts in ARDS. Proceedings of the Australian and New Zealand College of Anaesthetists (ANZCA) Annual Scientific Meeting. Retrieved from http://www.conference.co.nz/index.cfm/anzca10

2009

Journal - Research Article

Renfree, M. B., Hore, T. A., Shaw, G., Marshall Graves, J. A., & Pask, A. J. (2009). Evolution of genomic imprinting: Insights from marsupials and monotremes. Annual Review of Genomics & Human Genetics, 10, 241-262. doi: 10.1146/annurev-genom-082908-150026

Hann, C. E., Revie, J. A., Hewett, D., Chase, J. G., & Shaw, G. M. (2009). Screening for diabetic retinopathy using computer vision and physiological markers. Journal of Diabetes Science & Technology, 3(4), 819-834.

Le Compte, A., Chase, J. G., Lynn, A., Hann, C., Shaw, G., Wong, X.-W., & Lin, J. (2009). Blood glucose controller for neonatal intensive care: Virtual trials development and first clinical trials. Journal of Diabetes Science & Technology, 3(5), 1066-1081.

Seeley, M. J., Hu, W.-P., Scotter, J. M., Storer, M. K., & Shaw, G. M. (2009). In vitro SIFT-MS validation of a breath fractionating device using a model VOC and ventilation system. Journal of Breath Research, 3(1), 016001. doi: 10.1088/1752-7155/3/1/016001

Wong, X.-W., Chase, J. G., Le Compte, A. J., Hann, C. E., Lin, J., & Shaw, G. M. (2009). An adaptive clinical Type 1 diabetes control protocol to optimize conventional self-monitoring blood glucose and multiple daily-injection therapy. International Journal of Adaptive Control & Signal Processing, 23(5), 408-434. doi: 10.1002/acs.1069

Sundaresan, A., Yuta, T., Hann, C. E., Chase, J. G., & Shaw, G. M. (2009). A minimal model of lung mechanics and model-based markers for optimizing ventilator treatment in ARDS patients. Computer Methods & Programs in Biomedicine, 95(2), 166-180. doi: 10.1016/j.cmpb.2009.02.008

Conference Contribution - Published proceedings: Full paper

Hann, C. E., Chase, J. G., Desaive, T., Ypma, M. F., Elfring, J., & Shaw, G. M. (2009). The impact of model-based therapeutics on glucose control in an intensive care unit. In J. Vander Sloten, P. Verdonck, M. Nyssen & J. Haveisen (Eds.), IFMBE Proceedings. 22(11), (pp. 1570-1573). Berlin: Springer. doi: 10.1007/978-3-540-89208-3_373

Hann, C. E., Chase, J. G., Froissart, C. F., Starfinger, C., Desaive, T., Kok, K., … Shaw, G. M. (2009). Improving model-based cardiac diagnosis with an ECG. In J. Vander Sloten, P. Verdonck, M. Nyssen & J. Haveisen (Eds.), IFMBE Proceedings. 22(11), (pp. 1754-1757). Berlin: Springer. doi: 10.1007/978-3-540-89208-3_418

Desaive, T., Chase, J. G., Starfinger, C., Lambermont, B., Ghuysen, A., Kolh, P., … Shaw, G. M., & Hann, C. E. (2009). Patient-specific modelling of the cardiovascular system: Application to septic shock with a minimal data set. In O. Dössell & W. C. Schlegel (Eds.), IFMBE Proceedings. 25(7), (pp. 509-512). Springer. doi: 10.1007/978-3-642-03885-3

Hann, C. E., Chase, J. G., Desaive, T., Froissart, C., Revie, J., Stevenson, D., & Shaw, G. M. (2009). Unique parameter identification of a cardiovascular system model using feedback control. Proceedings of the IEEE International Conference on Control and Automation (ICCA). (pp. 631-636). IEEE. doi: 10.1109/ICCA.2009.5410501

Conference Contribution - Published proceedings: Abstract

Lin, J., Parente, J. D., Chase, J. G., Shaw, G. M., Blakemore, A., Le Compte, A., … Wang, S.-H. (2009). Development of a model-based clinical sepsis biomarker for critically ill patients. Proceedings of the 7th International Federation of Automatic Control (IFAC) Symposium on Modelling and Control in Biomedical Systems. doi: 10.3182/20090812-3-DK-2006.0076

Le Compte, A., Chase, J. G., Lynn, A., Hann, C. E., Shaw, G. M., & Lin, J. (2009). Blood glucose control in neonatal intensive care with model-based controllers. Proceedings of the 7th International Federation of Automatic Control (IFAC) Symposium on Modelling and Control in Biomedical Systems. doi: 10.3182/20090812-3-DK-2006.0031

Sundaresan, A., Hann, C. E., Chase, J. G., & Shaw, G. M. (2009). End expiratory volume can be estimated using a stress strain approach. Proceedings of the 7th International Federation of Automatic Control (IFAC) Symposium on Modelling and Control in Biomedical Systems. doi: 10.3182/20090812-3-DK-2006.0033

Hann, C. E., Chase, J. G., Revie, J. A., Hewett, D., & Shaw, G. M. (2009). Diabetic retinopathy screening using computer vision. Proceedings of the 7th International Federation of Automatic Control (IFAC) Symposium on Modelling and Control in Biomedical Systems. doi: 10.3182/20090812-3-DK-2006.0086

Docherty, P. D., Chase, J. G., Lotz, T., Hann, C. E., Shaw, G. M., Berkeley, J. E., Mann, J. I., & McAuley, K. A. (2009). DISTq: Low-cost, accurate and real-time estimation of insulin sensitivity. Proceedings of the 7th International Federation of Automatic Control (IFAC) Symposium on Modelling and Control in Biomedical Systems. doi: 10.3182/20090812-3-DK-2006.0052

Hann, C. E., Chase, J. G., Desaive, T., Froissart, C., Revie, J. A., Stevenson, D., … Shaw, G. M. (2009). Unique parameter identification for model-based cardiac diagnosis in critical care. Proceedings of the 7th International Federation of Automatic Control (IFAC) Symposium on Modelling and Control in Biomedical Systems. doi: 10.3182/20090812-3-DK-2006.0097

Hann, C. E., Chase, J. G., Desaive, T., Starfinger, C., Lambermont, B., Ghuysen, A., … Shaw, G. M. (2009). Model-based therapeutics for the cardiovascular system: A clinical focus. Proceedings of the 7th International Federation of Automatic Control (IFAC) Symposium on Modelling and Control in Biomedical Systems. doi: 10.3182/20090812-3-DK-2006.0057

Chase, J. G., Le Compte, A., Shaw, G. M., Lin, J., Pretty, C., Razak, N., … Lynn, A. M., … Suhaimi, F. (2009). Tight glycemic control: The leading role of insulin sensitivity in determining efficacy and thus outcome. Proceedings of the 7th International Federation of Automatic Control (IFAC) Symposium on Modelling and Control in Biomedical Systems. doi: 10.3182/20090812-3-DK-2006.0037

Lin, J., Razak, N., Chase, J. G., Wong, J., Pretty, C., Parente, J. D., … Shaw, G. M., & Hann, C. E. (2009). The effect of Glargine as basal insulin support for recovering critically ill and high dependency unit patients: An in silico study. Proceedings of the 7th International Federation of Automatic Control (IFAC) Symposium on Modelling and Control in Biomedical Systems. doi: 10.3182/20090812-3-DK-2006.0075

Pretty, C., Chase, J. G., Lin, J., Shaw, G. M., Le Compte, A., Razak, N., & Parente, J. D. (2009). Corticosteroids and insulin resistance in the ICU. Proceedings of the 7th International Federation of Automatic Control (IFAC) Symposium on Modelling and Control in Biomedical Systems. doi: 10.3182/20090812-3-DK-2006.0045

Conference Contribution - Verbal presentation and other Conference outputs

Berkeley, J., Shaw, G. M., Chase, J. G., McAuley, K. A., Lotz, T., Docherty, P., & Mann, J. (2009, July). Validation study of a novel test for measuring insulin sensitivity. Verbal presentation at the 33rd New Zealand Society for the Study of Diabetes Annual Scientific Meeting, Dunedin, New Zealand.

Film/Video/CD Rom

Fraser, R., Beaven, D., Scott, R., Willis, J., Shaw, G., & Chase, G. (2009). The Body, the Research, the Professor: Diabetes [Episode 2] [Film]. Christchurch, New Zealand: Canterbury Medical Research Foundation. Retrieved from http://www.cmrf.org.nz/Home/Videos/#vid1

2008

Journal - Research Article

Starfinger, C., Chase, J. G., Hann, C. E., Shaw, G. M., Lambermont, B., Ghuysen, A., … Desaive, T. (2008). Model-based identification and diagnosis of a porcine model of induced endotoxic shock with hemofiltration. Mathematical Biosciences, 216(2), 132-139. doi: 10.1016/j.mbs.2008.08.014

Starfinger, C., Chase, J. G., Hann, C. E., Shaw, G. M., Lambert, P., Smith, B. W., … Rees, S. (2008). Model-based identification of PEEP titrations during different volemic levels. Computer Methods & Programs in Biomedicine, 91(2), 135-144. doi: 10.1016/j.cmpb.2008.03.005

Chase, J. G., LeCompte, A., Shaw, G. M., Blakemore, A., Wong, J., Lin, J., & Hann, C. E. (2008). A benchmark data set for model-based glycemic control in critical care. Journal of Diabetes Science & Technology, 2(4), 584-594.

Wong, X.-W., Chase, J. G., Hann, C. E., Lotz, T. F., Lin, J., Le Compte, A. J., & Shaw, G. M. (2008). Development of a clinical type 1 diabetes metabolic system model and in silico simulation tool. Journal of Diabetes Science & Technology, 2(3), 424-435.

Blakemore, A., Wang, S.-H., Le Compte, A., Shaw, G. M., Wong, X.-W., Lin, J., … Chase, J. G. (2008). Model-based insulin sensitivity as a sepsis diagnostic in critical care. Journal of Diabetes Science & Technology, 2(3), 468-477.

Wong, J., Chase, J. G., Hann, C. E., Shaw, G. M., Lotz, T. F., Lin, J., & Le Compte, A. J. (2008). A subcutaneous insulin pharmacokinetic model for computer simulation in a diabetes decision support role: Model structure and parameter identification. Journal of Diabetes Science & Technology, 2(4), 658-671.

Wong, J., Chase, J. G., Hann, C. E., Shaw, G. M., Lotz, T. F., Lin, J., & Le Compte, A. J. (2008). A subcutaneous insulin pharmacokinetic model for computer simulation in a diabetes decision support role: Validation and simulation. Journal of Diabetes Science & Technology, 2(4), 672-680.

Wong, X.-W., Chase, J. G., Hann, C. E., Lotz, T. F., Lin, J., Le Compte, A. J., & Shaw, G. M. (2008). In silico simulation of long-term type 1 diabetes glycemic control treatment outcomes. Journal of Diabetes Science & Technology, 2(3), 436-449.

Lin, J., Lee, D., Chase, J. G., Shaw, G. M., Le Compte, A., Lotz, T., … Hann, C. E. (2008). Stochastic modelling of insulin sensitivity and adaptive glycemic control for critical care. Computer Methods & Programs in Biomedicine, 89(2), 141-152. doi: 10.1016/j.cmpb.2007.04.006

Chase, J. G., Wong, X.-W., Singh-Levett, I., Hollingsworth, L. J., Hann, C. E., Shaw, G. M., … Lin, J. (2008). Simulation and initial proof-of-concept validation of a glycaemic regulation algorithm in critical care. Control Engineering Practice, 16(3), 271-285. doi: 10.1016/j.conengprac.2007.04.009

Chase, J. G., Shaw, G., Le Compte, A., Lonergan, T., Willacy, M., Wong, X.-W., Lin, J., … Hann, C. (2008). Implementation and evaluation of the SPRINT protocol for tight glycaemic control in critically ill patients: A clinical practice change. Critical Care, 12. doi: 10.1186/cc6868

Lotz, T. F., Chase, J. G., McAuley, K. A., Shaw, G. M., Wong, X.-W., Lin, J., … Mann, J. I. (2008). Monte Carlo analysis of a new model-based method for insulin sensitivity testing. Computer Methods & Programs in Biomedicine, 89, 215-225. doi: 10.1016/j.cmpb.2007.03.007

Conference Contribution - Published proceedings: Full paper

Desaive, T., Lambermont, B., Ghuysen, A., Kolh, P., Dauby, P. C., Starfinger, C., … Shaw, G. M. (2008). Cardiovascular modelling and identification in septic shock: Experimental validation. IFAC Proceedings Volumes, 41(2), (pp. 8068-8073). doi: 10.3182/20080706-5-KR-1001.01362

Hann, C. E., Hewett, D., Chase, J. G., Rabczuk, T., Sundaresan, A., Chen, X., … Shaw, G. M. (2008). Image-based measurement of alveoli volume expansion in an animal model of a diseased lung. Proceedings of the 15th International Conference on Mechatronics and Machine Vision in Practice (M2VIP08). (pp. 5-10). IEEE. doi: 10.1109/MMVIP.2008.4749498

Pielmeier, U., Chase, J. G., Andreassen, S., Steenfeldt Nielsen, B., Haure, P., & Shaw, G. M. (2008). Prediction validation of two glycaemic control models in critical care. IFAC Proceedings Volumes, 17(1, Pt 1), (pp. 8074-8079). [Full Paper]

Conference Contribution - Published proceedings: Abstract

Parente, J., Razak, N., Lin, J., Pretty, C., Chase, G., & Shaw, G. (2008). Model based insulin sensitivity as a metabolic marker for sepsis in the ICU. Australasian Physical & Engineering Sciences in Medicine. 31(4), (pp. 375-376). [Abstract]

Chase, J. G., Shaw, G. M., Blakemore, A., Wang, S.-H., LeCompte, A. J., Wong, X.-W., Lin, J., … Hann, C. E. (2008). High(er) insulin sensitivity rules out sepsis in critical care. Proceedings of the American Diabetes Association's 68th Scientific Sessions. ADA. Retrieved from http://professional.diabetes.org/Presentations_Details.aspx?typ=1&sr=adv&cng=79&meeting=79

Le Compte, A. J., Chisholm, G., Pretty, C., Chase, J. G., Shaw, G. M., Razak, N., … Lin, J. (2008). Drug therapy and (model-based) metabolic markers: Is tight glucose control in critical care affected by drug choices? Australasian Physical & Engineering Sciences in Medicine. 31(4), (pp. 428-429). [Abstract]

Razak, N., Parente, J., Lin, J., Chase, J. G., Hann, C. E., Pretty, C., … Shaw, G. M. (2008). Clinical data validation of a new, physiologically relevant critical care glycaemic control model. Australasian Physical & Engineering Sciences in Medicine. 31(4), (pp. 373-374). [Abstract]

Hann, C. E., Chase, J. G., Shaw, G. M., Wong, J., Lin, J., Lotz, T., … Lonergan, T. (2008). The concept of minimal mathematical modelling to understand and improve glycemic control in critical care. Diabetes Research and Clinical Practice. 79(Suppl. 1), (pp. s43-s44). [Abstract]

Conference Contribution - Verbal presentation and other Conference outputs

Wong, X.-W., Chase, J. G., Shaw, G. M., Lin, J., Le Compte, A. J., & Hann, C. E. (2008, November). In silico Monte Carlo virtual trials of a model-based adaptive type 1 diabetes mellitus control protocol. Verbal presentation at the Eighth Annual Diabetes Technology Meeting, Bethesda, Maryland.

Shaw, G., Chase, J. G., Hann, C. E., Starfinger, C., Desaive, T., Kolh, P., … Kok, K. (2008, November). Making sense of the chaos: Model-based CVS monitoring and decision support in critical care. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.

Pretty, C., Parente, J., Razak, N., Lin, J., Le Compte, A. J., Shaw, G. M., … Chase, J. G. (2008, November). Clinical data validation of an improved, physiologically relevant critical care glycemic control model. Verbal presentation at the Eighth Annual Diabetes Technology Meeting, Bethesda, Maryland.

Le Compte, A. J., Lynn, A., Chase, J. G., Shaw, G. M., Russell, G., Blakemore, A., … Lin, J., & Hann, C. E. (2008, November). Neonatal glycemic control: Model validation and in silico virtual patient trials. Verbal presentation at the Eighth Annual Diabetes Technology Meeting, Bethesda, Maryland.

2007

Journal - Research Article

Becouze, P., Hann, C. E., Chase, J. G., & Shaw, G. M. (2007). Measuring facial grimacing for quantifying patient agitation in critical care. Computer Methods & Programs in Biomedicine, 87(2), 138-147. doi: 10.1016/j.cmpb.2007.05.005

Smith, B. W., Andreassen, S., Shaw, G. M., Jensen, P. L., Rees, S. E., & Chase, J. G. (2007). Simulation of cardiovascular system diseases by including the autonomic nervous system into a minimal model. Computer Methods & Programs in Biomedicine, 86(2), 153-160. doi: 10.1016/j.cmpb.2007.02.001

Starfinger, C., Hann, C. E., Chase, J. G., Desaive, T., Ghuysen, A., & Shaw, G. M. (2007). Model-based cardiac diagnosis of pulmonary embolism. Computer Methods & Programs in Biomedicine, 87(1), 46-60. doi: 10.1016/j.cmpb.2007.03.010

Shaw, G. M., Chase, J. G., Starfinger, C., Smith, B. W., Hann, C. E., Desaive, T., & Ghuysen, A. (2007). Modelling the cardiovascular system. Critical Care & Resuscitation, 9(3), 264-269.

Chase, J. G., Shaw, G. M., Lotz, T., LeCompte, A., Wong, J., Lin, J., … Hann, C. E. (2007). Model-based insulin and nutrition administration for tight glycaemic control in critical care. Current Drug Delivery, 4, 283-296. doi: 10.2174/156720107782151223

Journal - Research Other

Chase, J. G., & Shaw, G. M. (2007). Is there more to glycaemic control than meets the eye? Critical Care, 11(4). doi: 10.1186/cc6099

McAuley, K. A., Mann, J. I., Chase, J. G., Lotz, T. F., & Shaw, G. M. (2007). Point: HOMA: Satisfactory for the time being: HOMA: The best bet for the simple determination of insulin sensitivity, until something better comes along [Editorial]. Diabetes Care, 30(9), 2411-2413. doi: 10.2337/dc07-1067

Conference Contribution - Published proceedings: Full paper

Desaive, T., Ghuysen, A., Lambermont, B., Kolh, P., Dauby, P. C., Starfinger, C., … Shaw, G. M. (2007). Study of ventricular interaction during pulmonary embolism using clinical identification in a minimum cardiovascular system model. Proceedings of the 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS). (pp. 2976-2979). IEEE. doi: 10.1109/IEMBS.2007.4352954

Conference Contribution - Published proceedings: Abstract

Endre, Z. H., Bennett, M., Celi, L., Dastrala, S., Devarajan, P., Dean, J., Frampton, C., Henderson, S., … Shaw, G., Walker, R., & Westhuyzen, J. (2007). Urinary gamma glutamyl transpeptidase-alkaline phosphatase indexed to urinary creatinine (GGT-AP) is correlated with urinary neutrophil gelatinase associated lipocalin (NGAL) on admission to Intensive Care. Journal of the American Society of Nephrology, 18, (pp. 576A). [Abstract]

2006

Journal - Research Article

Lin, J., Lee, D., Chase, J. G., Shaw, G. M., Hann, C. E., Lotz, T., & Wong, J. (2006). Stochastic modelling of insulin sensitivity variability in critical care. Biomedical Signal Processing & Control, 1(3), 229-242. doi: 10.1016/j.bspc.2006.09.003

Chase, J. G., Shaw, G. M., Wong, X. W., Lotz, T., Lin, J., & Hann, C. E. (2006). Model-based glycaemic control in critical care: A review of the state of the possible. Biomedical Signal Processing & Control, 1, 3-21. doi: 10.1016/j.bspc.2006.03.002

Chase, J. G., Yuta, T., Mulligan, K. J., Shaw, G. M., & Horn, B. (2006). A novel mechanical lung model of pulmonary diseases to assist with teaching and training. BMC Pulmonary Medicine, 6, 21. doi: 10.1186/1471-2466-6-21

Chase, J. G., Hann, C. E., Jackson, M., Lin, J., Lotz, T., Wong, X.-W., & Shaw, G. M. (2006). Integral-based filtering of continuous glucose sensor measurements for glycaemic control in critical care. Computer Methods & Programs in Biomedicine, 82, 238-247.

Rudge, A. D., Chase, J. G., Shaw, G. M., Lee, D., & Hann, C. E. (2006). Parameter identification and sedative sensitivity analysis of an agitation-sedation model. Computer Methods & Programs in Biomedicine, 83, 211-221.

Smith, B. W., Chase, J. G., Shaw, G. M., & Nokes, R. I. (2006). Simulating transient ventricular interaction using a minimal cardiovascular system model. Physiological Measurement, 27, 165-179.

Shaw, G. M., Chase, J. G., Wong, J., Lin, J., Lotz, T., Le Compte, A. J., … Hann, C. E. (2006). Rethinking glycaemic control in critical illness: From concept to clinical practice change. Critical Care & Resuscitation, 8(2), 90-99.

Lonergan, T., Le Compte, A., Willacy, M., Chase, J. G., Shaw, G. M., Hann, C. E., … Lin, J., & Wong, X.-W. (2006). A pilot study of the SPRINT protocol for tight glycemic control in critically ill patients. Diabetes Technology & Therapeutics, 8(4), 449-462.

Wong, X. W., Singh-Levett, I., Hollingsworth, L. J., Shaw, G. M., Hann, C. E., Lotz, T., Lin, J., … Chase, J. G. (2006). A novel, model-based insulin and nutrition delivery controller for glycemic regulation in critically ill patients. Diabetes Technology & Therapeutics, 8(2), 174-190. doi: 10.1089/dia.2006.8.174

Lonergan, T., Le Compte, A., Willacy, M., Chase, J. G., Shaw, G. M., Wong, X.-W., … Lin, J., & Hann, C. E. (2006). A simple insulin-nutrition protocol for tight glycemic control in critical illness: Development and protocol comparison. Diabetes Technology & Therapeutics, 8(2), 191-206.

Hann, C. E., Chase, J. G., & Shaw, G. M. (2006). Integral-based identification of patient specific parameters for a minimal cardiac model. Computer Methods & Programs in Biomedicine, 81, 181-192.

Wong, X. W., Chase, J. G., Shaw, G. M., Hann, C. E., Lotz, T., Lin, J., … Andreassen, S. (2006). Model predictive glycaemic regulation in critical illness using insulin and nutrition input: A pilot study. Medical Engineering & Physics, 28(7), 665-681. doi: 10.1016/j.medengphy.2005.10.015

Rudge, A. D., Chase, J. G., Shaw, G. M., & Lee, D. (2006). Physiological modelling of agitation-sedation dynamics. Medical Engineering & Physics, 28(1), 49-59. doi: 10.1016/j.medengphy.2005.03.005

Rudge, A. D., Chase, J. G., Shaw, G. M., & Lee, D. (2006). Physiological modelling of agitation-sedation dynamics including endogenous agitation reduction. Medical Engineering & Physics, 28(7), 629-638. doi: 10.1016/j.medengphy.2005.10.008

Conference Contribution - Published proceedings: Full paper

Chase, G., Shaw, G. M., Hann, C. E., LeCompte, A., Lonergan, T., Willacy, M., … Lin, J., & Lotz, T. (2006). Clinical validation of a model-based glycaemic control design approach and comparison to other clinical protocols. Proceedings of the 28th IEEE Engineering in Medicine and Biology Society Annual International Conference. (pp. 59-62). New York: IEEE. doi: 10.1109/IEMBS.2006.260497

Chase, J. G., Wong, J., Lin, J., LeCompte, A., Lotz, T., Lonergan, T., … Shaw, G. M. (2006). Insulin + nutrition control for tight critical care glycaemic regulation. Proceedings of the 6th International Federation of Automatic Control Symposium on Modelling and Control in Biomedical Systems. (pp. 19-22). Oxford, UK: Elsevier for IFAC. Retrieved from http://www.ifac-papersonline.net/cgi-bin/links/page.cgi?g=Detailed/29883.html;d=1;browse=a

Hann, C. E., Andreassen, S., Smith, B. W., Shaw, G. M., Chase, J. G., & Jensen, P. L. (2006). Identification of time varying cardiac disease state using a minimal cardiac model with reflex actions (Invited session). Proceedings of the 14th International Federation of Automatic Control Symposium on System Identification. (pp. 475-480). Oxford, UK: Elsevier for IFAC. Retrieved from http://www.ifac-papersonline.net/cgi-bin/links/page.cgi?g=Detailed/25435.html;d=1;browse=a

Hann, C. E., Chase, J. G., Shaw, G. M., Andreassen, S., & Smith, B. W. (2006). Clinical cardiovascular identification with limited data and fast forward simulation. Proceedings of the 6th International Federation of Automatic Control Symposium on Modelling and Control in Biomedical Systems. (pp. 69-74). Oxford, UK: Elsevier for International Federation of Automatic Control. Retrieved from http://www.ifac-papersonline.net/cgi-bin/links/page.cgi?g=Detailed/29838.html;d=1;browse=a

Smith, B. W., Andreassen, S., Shaw, G. M., Rees, S. E., & Chase, J. G. (2006). Cardiovascular system modelling of heart-lung interaction during mechanical ventilation. Proceedings of the 6th International Federation of Automatic Control Symposium on Modelling and Control in Biomedical Systems. (pp. 453-458). Oxford, UK: Elsevier for IFAC. Retrieved from http://www.ifac-papersonline.net/cgi-bin/links/page.cgi?g=Detailed/29902.html;d=1;browse=a

Chase, J. G., Lin, J., Lee, D. S., Wong, J., Hann, C. E., & Shaw, G. M. (2006). Stochastic insulin sensitivity models for tight glycaemic control. Proceedings of the 6th International Federation of Automatic Control Symposium on Modelling and Control in Biomedical Systems. (pp. 345-350). Oxford, UK: Elsevier for IFAC. Retrieved from http://www.ifac-papersonline.net/cgi-bin/links/page.cgi?g=Detailed/29884.html;d=1;browse=a

Wong, J., Shaw, G. M., Hann, C. E., Lotz, T., Lin, J., & Chase, J. G. (2006). Impact of system identification methods in metabolic modelling and control (Invited session). Proceedings of the 14th International Federation of Automatic Control Symposium on System Identification. (pp. 469-474). Oxford, UK: Elsevier for IFAC. Retrieved from http://www.ifac-papersonline.net/cgi-bin/links/page.cgi?g=Detailed/25434.html;d=1;browse=a

Conference Contribution - Published proceedings: Abstract

Shaw, G. M., Chase, J. G., Wong, X. W., Lin, J., Lotz, T., LeCompte, A., … Hann, C. E. (2006). Tight glycaemic control with a variable insulin and nutrition protocol. Anaesthesia & Intensive Care, 34(4), (pp. 543). [Abstract]

Chase, J. G., Lin, J., Lee, D., Shaw, G. M., Lotz, T., Hann, C. E., & Wong, J. (2006). Modelling stochastic insulin sensitivity variability in critical care. New Zealand Medical Journal, 119(1231). Retrieved from http://journal.nzma.org.nz/journal/119-1231/1922/content.pdf

Wong, X. W., Chase, J. G., Shaw, G. M., Lin, J., Lotz, T., & Hann, C. E. (2006). Clinical trials of active and adaptive insulin and nutrition control to control hyperglycaemia in critically ill patients. New Zealand Medical Journal, 119(1231). Retrieved from http://journal.nzma.org.nz/journal/119-1231/1922/content.pdf

Chase, J. G., Lotz, T. F., McAuley, K. A., Shaw, G. M., Hann, C. E., Lin, J., & Mann, J. I. (2006). Model-based assessment of insulin resistance in broad populations. New Zealand Medical Journal, 119(1231). Retrieved from http://journal.nzma.org.nz/journal/119-1231/1922/content.pdf

Conference Contribution - Poster Presentation (not in published proceedings)

Chase, J. G., Chen, X., Sirisena, H., Shaw, G., Wong, X. W., Hann, C. E., … Lin, J., & Lotz, T. (2006, November). Hierarchical real-time filtering for continuous glucose sensor data. Poster session presented at the 6th Annual Diabetes Technology Meeting, Atlanta, USA.

Lotz, T., Chase, J. G., McAuley, K. A., Shaw, G. M., Wong, X.-W., Lin, J., … Mann, J. I. (2006, November). Highly correlated model-based testing of insulin sensitivity: Initial results for a proposed low-intensity test. Poster session presented at the 6th Annual Diabetes Technology Meeting, Atlanta, USA.

Chase, J. G., Shaw, G., LeCompte, A., Lee, D., Lonergan, T., Willacy, M., … Lin, J., … Hann, C. (2006, November). Tight glycaemic control in critical care using insulin and nutrition: The SPRINT protocol. Poster session presented at the 6th Annual Diabetes Technology Meeting, Atlanta, USA.

Conference Contribution - Verbal presentation and other Conference outputs

Shaw, G. M., Chase, J. G., & Yuta, T. (2006, May). Man and machines: Insights into ventilation strategies. Invited presentation at the Australian and New Zealand College of Anaesthetists Annual Scientific Meeting, Adelaide, Australia.

Shaw, G. M., & Chase, J. G. (2006, May). Think smart or drive blind: Sensors and models in critical illness. Invited presentation at the Australian and New Zealand College of Anaesthetists Annual Scientific Meeting, Adelaide, Australia.

Shaw, G. M., Chase, J. G., Wong, J., Lin, J., Lotz, T., LeCompte, A., … Hann, C. E. (2006, April). The SPRINT protocol for tight glycaemic control. Verbal presentation at the Australia and New Zealand Intensive Care Society Annual Scientific Meeting, Christchurch, New Zealand.

Starfinger, C., Hann, C. E., Chase, J. G., Shaw, G. M., Lambert, P., Smith, B. W., … Ghuysen, A. (2006, October). Haemodynamic management using a minimal cardiac model. Verbal presentation at the Pulsion Medical Systems AG Young Researchers Meeting on Haemodynamic Management, Munich, Germany.

Shaw, G. M., Chase, J. G., Yuta, T., Horn, B., & Hann, C. E. (2006, April). Optimising ventilation using a simple model of the ventilated ARDS lung. Verbal presentation at the Australia and New Zealand Intensive Care Society Annual Scientific Meeting, Christchurch, New Zealand.

Shaw, G. M., Endre, Z., LeCompte, A., Jung Jo, H., Chase, J. G., & Hann, C. E. (2006, April). Modeling renal function to assess markers of acute renal failure. Verbal presentation at the Australia and New Zealand Intensive Care Socety (ANZICS) Annual Scientific Meeting, Christchurch, New Zealand.

Shaw, G. M., Chase, J. G., Starfinger, C., & Hann, C. E. (2006, April). Future quality improvements in critical care in sedation management and cardiovascular modeling. Verbal presentation at the Australia and New Zealand Intensive Care Society Annual Scientific Meeting, Christchurch, New Zealand.

Shaw, G. M. (2006, March). Don't drive blind! Applied mathematics in the intensive care unit. Plenary presentation at the AMSI/MASCOS Industry Forum: Mathematical Opportunities in Health Care, Melbourne, Australia.

2005

Journal - Research Article

Hann, C. E., Chase, J. G., Lin, J., Lotz, T. F., Doran, C. V., & Shaw, G. M. (2005). Integral-based parameter identification for long-term dynamic verification of a glucose-insulin system model. Computer Methods & Programs in Biomedicine, 77, 259-270.

Chase, J. G., Shaw, G. M., Lin, J., Doran, C. V., Hann, C. E., Robertson, M. B., … Broughton, B. (2005). Adaptive bolus-based targeted glucose regulation of hyperglycaemia in critical care. Medical Engineering & Physics, 27, 1-11.

Smith, B. W., Chase, J. G., Shaw, G. M., & Nokes, R. I. (2005). Experimentally verified minimal cardiovascular system model for rapid diagnostic assistance. Control Engineering Practice, 13, 1183-1193.

Lee, D. S., Rudge, A. D., Chase, J. G., & Shaw, G. M. (2005). A new model validation tool using kernel regression and density estimation. Computer Methods & Programs in Biomedicine, 80, 75-87.

Chase, J. G., Shaw, G. M., Lin, J., Doran, C. V., Bloomfield, M., & Wake, G. C. (2005). Impact of insulin-stimulated glucose removal saturation on dynamic modelling and control of hyperglycaemia. International Journal of Intelligent Systems Technologies & Applications, 1(1-2), 79-80.

Rudge, A. D., Chase, J. G., Shaw, G. M., Lee, D., Wake, G. C., Hudson, I. L., & Johnston, L. (2005). Impact of control on agitation-sedation dynamics. Control Engineering Practice, 13, 1139-1149.

Chase, J. G., Shaw, G. M., Lin, J., Doran, C. V., Hann, C. E., Lotz, T. F., … Broughton, B. (2005). Target glycemic reduction in critical care using closed-loop control. Diabetes Technology & Therapeutics, 7(2), 274-282.

Chase, J. G., Rudge, A. D., Lee, D. S., & Shaw, G. M. (2005). H∞ control analysis of patient agitation management in critically ill. International Journal of Intelligent Systems Technologies & Applications, 1(1-2), 111-125.

Hann, C. E., Chase, J. G., & Shaw, G. M. (2005). Efficient implementation of non-linear valve law and ventricular interaction dynamics in the minimal cardiac model. Computer Methods & Programs in Biomedicine, 80, 65-74.

Journal - Research Other

O'Connell, O., Rhodes, B., Shaw, G., & Beckert, L. (2005). Heathrow to ICU direct [Case report]. New Zealand Medical Journal, 118(1212). Retrieved from http://journal.nzma.org.nz/journal/118-1212/1377/content.pdf

Conference Contribution - Published proceedings: Full paper

Chase, J. G., Lonergan, T. R., Le Compte, A. J., Willacy, M. B., Shaw, G. M., Wong, X. W., & … (2005). Tight glucose control in critically ill patients using a specialized insulin-nutrition table. Proceedings of the 12th International Conference on Biomedical Engineering. [CD-ROM], 12. Singapore. [Full Paper]

Chase, J. G., Yuta, T., Shaw, G. M., Horn, B., & Hann, C. E. (2005). A minimal model of mechanically ventilated lung mechanics to optimize ventilation therapy in the treatment of ARDS in critical care. Proceedings of the 12th International Conference on Biomedical Engineering. [CD-ROM], 12. Singapore. [Full Paper]

Lotz, T. F., Chase, J. G., McAuley, K. A., Shaw, G. M., Hann, C. E., & Mann, J. I. (2005). A highly correlated method to assess insulin resistance in broad populations. Proceedings of the 12th International Conference on Biomedical Engineering. [CD-ROM], 12. Singapore. [Full Paper]

Hann, C. E., Chase, J. G., & Shaw, G. M. (2005). Efficient implementation of a non-linear cardio-vascular system model for real-time therapy assistance in critical care. Proceedings of the 12th International Conference on Biomedical Engineering. [CD-ROM], 12. Singapore. [Full Paper]

Lin, J., Lee, D., Chase, J. G., Shaw, G. M., Hann, C. E., Lotz, T., & Wong, X. W. (2005). Stochastic modelling of insulin sensitivity variability in critical care. Proceedings of the 12th International Conference on Biomedical Engineering. [CD-ROM], 12. Singapore. [Full Paper]

Rudge, A. D., Chase, J. G., Shaw, G. M., & Lee, D. S. (2005). Derivative-focused control of agitation-sedation dynamics in critically ill patients. Proceedings of the 12th International Conference on Biomedical Engineering. [CD-ROM], 12. Singapore. [Full Paper]

Chase, J. G., Lin, J., Lee, D., Shaw, G. M., Lotz, T., Hann, C. E., & Wong, J. (2005). Modelling stochastic insulin sensitivity variability in critical care. Proceedings of the Canterbury Health Research Conference. Christchurch, New Zealand: Canterbury Medical Research Foundation. [Full Paper]

Chase, J. G., Wong, X. W., Shaw, G. M., Hann, C. E., Lin, J., & Lotz, T. (2005). Clinical trials of active insulin and nutrition control in critically ill patients. Proceedings of the 12th International Conference on Biomedical Engineering. [CD-ROM], 12. Singapore. [Full Paper]

Chase, J. G., Lotz, T. F., McAuley, K. A., Shaw, G. M., Hann, C. E., Lin, J., & Mann, J. I. (2005). Model-based assessment of insulin resistance in broad populations. Proceedings of the Canterbury Health Research Conference. Christchurch, New Zealand: Canterbury Medical Research Foundation. [Full Paper]

Wong, X. W., Chase, J. G., Shaw, G. M., Hann, C. E., Lin, J., & Lotz, T. (2005). Comparison of adaptive and sliding-scale glycaemic control in critical care and the impact of nutritional inputs. Proceedings of the 12th International Conference on Biomedical Engineering. [CD-ROM], 12. Singapore. [Full Paper]

Rudge, A. D., Chase, J. G., Lee, D. S., & Shaw, G. M. (2005). Physiologically-based model of agitation-sedation dynamics in critically ill patients incorporating endogenous agitation reduction. Proceedings of the 12th International Conference on Biomedical Engineering. [CD-ROM], 12. Singapore. [Full Paper]

Hann, C. E., Chase, J. G., Andreassen, S., Smith, B. W., & Shaw, G. M. (2005). Simulating cardiac disease from onset with a minimal cardiac model including reflex actions. Proceedings of the 12th International Conference on Biomedical Engineering. [CD-ROM], 12. Singapore. [Full Paper]

Conference Contribution - Published proceedings: Abstract

Wong, X. W., Chase, J. G., Shaw, G. M., Lin, J., Lotz, T., & Hann, C. E. (2005). Clinical trials of active and adaptive insulin and nutrition control to control hyperglycaemia in critically ill patients. Proceedings of the Canterbury Health Research Conference. Christchurch, New Zealand: Canterbury Medical Research Foundation. [Abstract]

Wong, X. W., Shaw, G. M., Chase, J. G., Hann, C. E., Lotz, T., & Lin, J. (2005). Active insulin control with variable nutrition for targeted glucose control in critically ill patients. New Zealand Medical Journal, 118(1218). Retrieved from http://journal.nzma.org.nz/journal/118-1218/1567/content.pdf

Shaw, G. (2005). Evidence based medicine is [not] the way forward. Proceedings of the 30th Australian and New Zealand Annual Scientific Meeting on Intensive Care. (pp. 207). Adelaide, Australia. [Abstract]

Chase, J. G., Lonergan, T., Le Compte, A., Willacy, M., Shaw, G. M., Wong, X. W., Lin, J., … Hann, C. (2005). Computer simulations of tight glucose control in critically ill patients using a specialized insulin-nutrition-table. New Zealand Medical Journal, 118(1218). Retrieved from http://journal.nzma.org.nz/journal/117-1192/855/content.pdf

Hann, C. E., Chase, J. G., Andreassen, S., Smith, B. W., & Shaw, G. M. (2005). Diagnosis using a minimal cardiac model including reflex actions. Intensive Care Medicine. Suppl. 1, (pp. S18). [Abstract]

Conference Contribution - Verbal presentation and other Conference outputs

Shaw, G. (2005, November). Closed loop ICU agitation control system. Verbal presentation at the 6th Invited Conference on Pain Management and ICU Sedation, San Diego, CA, USA.

2004

Journal - Research Article

Doran, C. V., Chase, J. G., Shaw, G. M., Moorhead, K. T., & Hudson, N. H. (2004). Derivative weighted active insulin control algorithms and intensive care unit trials. Control Engineering Practice, 13, 1129-1137.

Dzendrowskyj, P., Shaw, G., & Johnston, L. (2004). Effects of nursing industrial action on relatives of Intensive Care Unit patients: A 16-month follow-up. New Zealand Medical Journal, 117(1205). Retrieved from http://journal.nzma.org.nz/journal/117-1205/1150/content.pdf

Doran, C. V., Hudson, N. H., Moorhead, K. T., Chase, J. G., Shaw, G. M., & Hann, C. E. (2004). Derivative weighted active insulin control modelling and clinical trials for ICU patients. Medical Engineering & Physics, 26, 855-866.

Chase, J. G., Rudge, A. D., Shaw, G. M., Wake, G. C., Lee, D., Hudson, I. L., & Johnston, L. (2004). Modeling and control of the agitation-Sedation cycle for critical care patients. Medical Engineering & Physics, 26, 459-471. Elsevier.

Smith, B. W., Chase, J. G., Nokes, R. I., Shaw, G. M., & Wake, G. (2004). Minimal haemodynamic system model including ventricular interaction and valve dynamics. Medical Engineering & Physics, 26(2), 131-139.

Chase, J. G., Agogue, F., Starfinger, C., Lam, Z., Shaw, G. M., Rudge, A. D., & Sirisena, H. (2004). Quantifying agitation in sedated ICU patients using digital imaging. Computer Methods & Programs in Biomedicine, 76(2), 131-141.

Chase, J. G., Starfinger, C., Lam, Z. H., Agogue, F., & Shaw, G. M. (2004). Quantifying agitation in sedated ICU patients using heart rate and blood pressure. Physiological Measurement, 25, 1037-1051.

Doran, C. V., Chase, J. G., Shaw, G. M., Moorhead, K. T., & Hudson, N. H. (2004). Automated insulin infusion trials in the intensive care unit. Diabetes Technology & Therapeutics, 6(2), 155-165.

Conference Contribution - Published proceedings: Full paper

Rudge, A. D., Chase, J. G., Shaw, G. M., & Lee, D. (2004). Physiologically-based minimal model of agitation-sedation dynamics. Proceedings of the 26th Annual International Conference of the IEEE EMBS. [CD-ROM] [Full Paper]

Hann, C. E., Chase, J. G., Smith, B. W., & Shaw, G. M. (2004). Computationally efficient velocity profile solutions for cardiac haemodynamics. Proceedings of the 26th International Conference of Engineering in Medicine and Biology Society. 2, (pp. 944-947). [Full Paper]

Lin, J., Chase, J. G., Shaw, G. M., Lotz, T. F., Hann, C. E., Doran, C. V., & Lee, D. S. (2004). Long term verification of glucose-insulin regulatory system model dynamics. Proceedings of the 26th International Conference of Engineering in Medicine and Biology Society. 7, (pp. 758-761). [Full Paper]

Hann, C. E., Chase, J. G., Shaw, G. M., & Smith, B. W. (2004). Identification of patient specific parameters for a minimal cardiac model. Proceedings of the 26th International Conference of Engineering in Medicine and Biology Society. 2, (pp. 813-816). [Full Paper]

Chase, J. G., Shaw, G. M., Lin, J., Doran, C. V., Hann, C. E., Robertson, M. B., … Broughton, B. (2004). Adaptive bolus-based set-point regulation of hyperglycemia in critical care. Proceedings of the 26th International Conference of Engineering in Medicine and Biology Society. 7, (pp. 3463-3466). [Full Paper]

Rudge, A. D., Chase, J. G., Shaw, G. M., & Lee, D. (2004). Automated agitation management accounting for saturation dynamics. Proceedings of the 26^th International Conference of IEEE Engineering in Medicine and Biology Society. (pp. 3459-3462). [Full Paper]

Yuta, T., Chase, J. G., Shaw, G. M., & Hann, C. (2004). Dynamic models of ARDS lung mechanics for optimal patient ventilation. Proceedings of the 26th International Conference of Engineering in Medicine and Biology Society. 2, (pp. 861-864). [Full Paper]

Conference Contribution - Published proceedings: Abstract

Rudge, A. D., Shaw, G. M., Chase, J. G., & Lee, D. (2004). Analysis of model-based clinical sedation management. Proceedings of the NZPEM 50th Anniversary Conference. Christchurch, New Zealand. [Abstract]

Shaw, G. (2004). A low-flow portable continuous positive airway (CPAP) device for emergency use. Proceedings of the Australasian College for Emergency Medicine Australasian Scientific Conference. (pp. 40). Adelaide, Australia: ACEM. [Abstract]

Greenfield, K., Dove, R., & Shaw, G. (2004). An automated method for reducing over-sedation of critically ill patients in intensive care. Proceedings of the NZPEM 50th Anniversary Conference. (pp. 35). Christchurch, New Zealand. [Abstract]

Yuta, T., Chase, J. G., Shaw, G. M., & Hann, C. E. (2004). ARDS lung mechanics for optimizing ventilator treatment. Proceedinsg of the Canterbury Health Science Research Conference. [Abstract]

Smith, B. W., Chase, J. G., & Shaw, G. M. (2004). Minimal model simulation of diseases affecting the cardiovascular system. Intensive Care Medicine. Suppl. 1, (pp. S25). [Abstract]

Yuta, T., Chase, J. G., & Shaw, G. M. (2004). Improved model of ARDS lung mechanics for decision-support clinical tool. Proceedings of the NZPEM 50th Anniversary Conference. Christchurch, New Zealand. [Abstract]

Lotz, T. F., Chase, J. G., Shaw, G. M., Hann, C. E., & McAuley, K. A. (2004). Advanced modeling of glucose and insulin kinetics for adaptive tight regulation of hyperglycaemia. Proceedings of the Canterbury Health Science Research Conference. [Abstract]

Doran, C. V., Bloomfield, M., Lee, D., Shaw, G. M., Chase, J. G., Lin, J., & Lotz, T. F. (2004). Effect of hyperglycemia on mortality in the Christchurch Intensive Care Unit. Proceedings of the 34th Annual General Meeting of the Christchurch Medical Research Society. (pp. 1-5). [Abstract]

Hudson, I. L., Kang, I., Rudge, A. D., Chase, J. G., & Shaw, G. M. (2004). Wavelet signatures of agitation and sedation profiles: A preliminary study. Proceedings of the NZPEM 50th Anniversary Conference. Christchurch, New Zealand. [Abstract]

Hann, C. E., Chase, J. G., Shaw, G. M., & Smith, B. W. (2004). Fast identification of a minimal cardiac model. Proceedings of the NZPEM 50th Anniversary Conference. Christchurch, New Zealand. [Abstract]

Agogue, F., Chase, J. G., & Shaw, G. M. (2004). Physiological signals and derivatives to quantify agitation in the critically ill. Proceedings of the NZPEM 50th Anniversary Conference. Christchurch, New Zealand. [Abstract]

Shaw, G. M. (2004). Physiologically-based minimal model of agitation-sedation dynamics. Canterbury Health Science Research Conference. [Abstract]

Shaw, G., Chase, G., Doran, C., Lin, J., Lotz, T., Lee, D., & Bloomfield, M. (2004). Peak and range of blood glucose are also associated wtih ICU mortality. Critical Care Medicine. 32(12), (pp. A125). [Abstract]

Chase, J. G., Rudge, A. D., Shaw, G. M., & Lee, D. (2004). Sedation managemnet in the critically ill using dyanmic systems modeling. Proceedings of the New Zealand Mathematics Colloquium. Dunedin, New Zealand: University of Otago. [Abstract]

Shaw, G., Chase, G., Rudge, A., Lee, D., Hooper, E., & Agogue, F. (2004). Emerging methods for sedation and agitation management in critical illness. Critical Care Medicine. 32(12), (pp. A97). [Abstract]

Agogue, F., Chase, J. G., & Shaw, G. M. (2004). Measuring agitation in the critically ill-multiple signal derivative method. Proceedings of the Cantebury Health Science Research Conference. [Abstract]

Lotz, T., Chase, J. G., McAuley, K. A., Lin, J., Shaw, G. M., & Hann, C. E. (2004). Highly correlated model-based measures of insulin sensitivity. Proceedings of the NZPEM 50th Anniversary Conference. [Abstract]

Shaw, G. M., Chase, J. G., Lee, D., Bloomfield, M., Doran, C. V., & Lin, J. (2004). How high ARE blood glucose levels in intensive care? Proceedings of the Australia-New Zealand Intensive Care Society ASM. [Abstract]

Shaw, G. M., Chase, J. G., Lee, D., Hooper, E., Rudge, A. D., & Agogue, F. (2004). Emerging methods for sedation and agitation management in critical illness. Proceedings of the Australia-New Zealand Intensive Care Society ASM. [Abstract]

Shaw, G. M., Chase, J. G., Lee, D., Wake, G. C., Lin, J., Browne, P., … Doran, C. V. (2004). Targeted glucose control in critically ill patients. Proceedings of the Australia-New Zealand Intensive Care Society ASM. [Abstract]

Conference Contribution - Poster Presentation (not in published proceedings)

Rudge, A., Chase, J. G., & Shaw, G. M. (2004, July). Developing drug delivery approaches to improve patient healthcare [Winner of the McDiarmid Young Scientist of the Year]. Poster session presented at the McDiarmid Young Scientist of the Year Awards.

2003

Journal - Research Article

Shaw, G. M., Chase, J. G., Rudge, A. D., Starfinger, C., Lam, Z. H., Lee, D., … Dove, R. (2003). Rethinking sedation and agitation management in critical illness. Critical Care & Resuscitation, 5, 198-206.

Wilson, P., Freeman, C. G., McEwan, M. J., Allardyce, R. A., & Shaw, G. M. (2003). SIFT-MS measurement of VOC distribution coefficients in human blood constituents and urine. Applied Occupational & Environmental Hygiene, 18(10), 759-763.

Smith, B. W., Chase, J. G., Nokes, R. I., Shaw, G. M., & David, T. (2003). Velocity profile method for time varying resistance in minimal cardiovascular system models. Physics in Medicine & Biology, 48(20), 3375-3387.

Dzendrowskyj, P., Bowie, D., & Shaw, G. (2003). Transport services under stress: Patient air transfers due to industrial action in Christchurch. New Zealand Medical Journal, 116(1177). Retrieved from http://journal.nzma.org.nz/journal/116-1177/497/content.pdf

Journal - Research Other

Shaw, G. M. (2003). Drotrecogin alpha (activated): a magic bullet or budget blowout? [Comment]. New Zealand Medical Journal, 116(1181). Retrieved from http://journal.nzma.org.nz/journal/116-1181/586/content.pdf

Shaw, G. M., & Chase, J. G. (2003). Sedation and agitation in the critically ill patient [Correspondence]. Critical Care & Resuscitation, 5, 311.

Journal - Professional & Other Non-Research Articles

Shaw, G. M. (2003). Drotrecogin alpha (activated): A magic bullet or budget blowout? Comment on [Drotrecogin alfa (recombinant human activated protein C) in severe sepsis: A New Zealand viewpoint]. New Zealand Medical Journal, 116(1181). Retrieved from http://journal.nzma.org.nz/journal/116-1181/586/content.pdf

Conference Contribution - Published proceedings: Full paper

Tracey, B., Shaw, G., & White, K. (2003). CPAP in a paediatric ward: Was it a good move? Proceedings of the Paediatric Society of New Zealand 56th Annual Scientific Meeting. [Full Paper]

Smith, B. W., Chase, J. G., Nokes, R. I., Coope, I. D., & Shaw, G. M. (2003). Optimisation based identification of cardiovascular system model parameters for patient specific diagnostic assistance. Proceedings of the World Congress on Medical Physics and Biomedical Engineering. [Full Paper]

Rudge, A. D., Chase, J. G., Shaw, G. M., & Wake, G. C. (2003). Improved agitation management in critically ill patients via feedback control of sedation administration. Proceedings of the World Congress on Medical Physics and Biomedical Engineering. [Full Paper]

Lam, Z. H., Starfinger, C., Chase, J. G., Shaw, G. M., & Agogue, F. (2003). Movement quantification for use in agitation in sedated ICU patients. Proceedings of the World Congress on Medical Physics and Biomedical Engineering. [Full Paper]

Starfinger, C., Lam, Z. H., Chase, J. G., Shaw, G. M., & Agogue, F. (2003). Measurement of agitation in sedated ICU patients using adaptive signal processing and fuzzy mathematics. Proceedings of the World Congress on Medical Physics and Biomedical Engineering. [Full Paper]

Rudge, A. D., Chase, J. G., Shaw, G. M., Johnston, L., & Wake, G. C. (2003). Modelling and control of the agitation-sedation cycle. Proceedings of the 5th IFAC Symposium on Modelling and Control in Biomedical Systems. (pp. 89-95). [Full Paper]

Chase, J. G., Shaw, G. M., Doran, C. V., Hudson, N. H., & Moorhead, K. T. (2003). Derivative weighted active insulin control algorithms and trials. Proceedings of the 5th IFAC Symposium on Modelling and Control of Biomedical Systems. (pp. 83-89). [Full Paper]

Smith, B. W., Chase, J. G., Shaw, G. M., & Nokes, R. I. (2003). A minimal cardiovascular system haemodynamic model for rapid diagnostic assistance. Proceedings of the 5th IFAC Symposium on Modelling and Control in Biomedical Systems. (pp. 427-433). [Full Paper]

Conference Contribution - Published proceedings: Abstract

Chase, J. G., Lam, Z. H., Starfinger, C., Shaw, G. M., Agogue, F., & Sirisena, H. R. (2003). Quantifying agitation in sedated intensive-care patients. New Zealand Medical Journal, 116(1174). Retrieved from http://journal.nzma.org.nz/journal/116-1174/443/content.pdf

Shaw, G. M., Dove, R. A., Greenfield, K. M., & Chase, J. G. (2003). A computerised approach to sedation administration in critically ill patients. Proceedings of the Australian and New Zealand Intensive Care Society New Zealand Annual Scientific Meeting on Intensive Care. Dunedin, New Zealand: ANZICS. [Abstract]

Lee, D. S., Rudge, A. D., Chase, J. G., Shaw, G. M., Johnston, L., & Wake, G. C. (2003). Dynamic model assessment using a probability band for local linear kernal regression, with an application in agitation-sedation modeling. Proceedings of the New Zealand Statistical Association 54th Annual Conference. Massey University, Palmerston North: NZSA. [Abstract]

Shaw, G. M., Chase, J. G., Doran, C. V., Hudson, N. L., & Moorhead, K. T. (2003). Active insulin control in critically ill patients with glucose intolerance. Proceedings of the Australian and New Zealand Intensive Care Society ASM on Intensive Care. Dunedin: ANZICS. [Abstract]

2002

Journal - Research Article

Werno, A. M., Klena, J. D., Shaw, G. M., & Murdoch, D. R. (2002). Fatal case of Campylobacter lari prosthetic joint infection and bacteremia in an immunocompetent patient. Journal of Clinical Microbiology, 40(3), 1053-1055.

Wilson, P. F., Freeman, C., McEwan, M. J., Milligan, D. B., Allardyce, R. A., & Shaw, G. M. (2002). In situ analysis of solvents on breath and blood: A selected ion flow tube mass spectrometric study. Rapid Communications in Mass Spectrometry, 16, 427-432.

Conference Contribution - Published proceedings: Full paper

Chase, J. G., Wake, G. C., Lam, Z. H., Lee, J. Y., Hwang, K. S., & Shaw, G. (2002). Steady-state optimal insulin infusion for hyperglycemic ICU patients. Proceedings of the 7th International Conference on Control, Automation, Robotics and Vision. [CD-ROM] [Full Paper]

Conference Contribution - Published proceedings: Abstract

Shaw, G. M., Chase, J. G., Doran, C. V., Hudson, N. H., & Moorhead, K. T. (2002). Insulin infusion controller provides tight glucose control in ICU patients. Proceedings of the 27th Australian and New Zealand Annual Scientific Meeting on Intensive Care and the 8th Australian and New Zealand Paediatric and Neonatal Intensive Care Conference. (pp. 236). [Abstract]

Rudge, A. D., Shaw, G., & Chase, J. G. (2002). Sedative drug administration patterns in surviving and non-surviving critically ill patients. New Zealand Medical Journal, 115(1161). [Abstract]

Lam, Z. H., Hunt, S., Chase, J. G., & Shaw, G. (2002). Patient agitation and heart rate variability. New Zealand Medical Journal, 115(1157). [Abstract]

Shaw, G. M. (2002). ′Inspirational′ CPAP: From the bottoms of oceans to tops of mountains. Proceedings of the 8th ANZICS and ACCCN Continuing Education Meeting. (pp. 11-12). Launceston, Australia. [Abstract]

Shaw, G. M., Rudge, A., Chase, J. G., Greenfield, K. M., & Dove, R. A. (2002). Patterns of sedation administration in critical illness. Proceedings of the 27th Australian and New Zealand Annual Scientific Meeting on Intensive Care and the 8th Australian and New Zealand Paediatric and Neonatal Intensive Care Conference. (pp. 235). [Abstract]

Conference Contribution - Verbal presentation and other Conference outputs

Doig, & Shaw, G. (2002, August). Evidence based medicine: ″Myth or magic?″ A debate. Verbal presentation at the 8th ANZICS and ACCCN Continuing Education Meeting, Launceston, Tasmania, Australia.

2001

Journal - Research Article

Goodisson, D. W., Shaw, G. M., & Snape, L. (2001). Intracranial intubation in patients with maxillofacial injuries associated with base of skull fractures. Journal of Trauma, 50(2), 363-366.

Wilson, P. F., Freeman, C. G., McEwan, M. J., Milligan, D. B., Allardyce, R. A., & Shaw, G. M. (2001). Alcohol in breath and blood: A selected ion flow tube mass spectrometric study. Rapid Communications in Mass Spectrometry, 15(6), 413-417. doi: 10.1002/rcm.244

Conference Contribution - Published proceedings: Abstract

Shaw, G. M. (2001). The future of intensive care in New Zealand. Proceedings of the ANZICS New Zealand Scientific Meeting on Intensive Care. (pp. 47). [Abstract]

Shaw, G. M. (2001). A new continuous-flow CPAP device using low fresh gas flows. Proceedings of the 8th World Congress of Intensive and Critical Care Medicine. (pp. 70). [Abstract]

2000

Chapter in Book - Other

Shaw, G. M. (2000). High frequency ventilation: The quest to minimise lung injury. In Australasian Anaesthesia. (pp. 181-190). Australian and New Zealand College of Anaesthetists.

Journal - Research Other

Stevens, J. M., Patton, W. N., Heaton, D. C., Spearing, R. L., Shaw, G., Bowie, D., … Comenzo, R. (2000). Autologous PBSCT in patients with cardia amyloidosis. Bone Marrow Transplantation, 26(5), 588-589.

Conference Contribution - Published proceedings: Abstract

Shaw, G. M. (2000). Where have all the professors gone? Long time passing... Proceedings of the New Zealand ANZICS Conference. (pp. 18). [Abstract]