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Michael Epton

BM BS BMedSci(Hons) MRCP(UK) FRACP PhD

Email michael.epton@cdhb.health.nz

Canterbury Respiratory Research Group
40 Stewart St
Christchurch
New Zealand

Current Roles

  • 2016 - Present
    Adjunct Professor, Departments of Geography, and Communication Disorders, University of Canterbury, Christchurch, New Zealand
  • November 2014 - Present
    Investigator (Christchurch Clinical Studies Trust, New Zealand)
  • February 2010 - Present
    Community Respiratory Physician, Canterbury Initiative, Christchurch, New Zealand
  • January 2009 - Present
    Consultant Physician, Department of Respiratory Medicine, Christchurch Hospital, New Zealand
  • July 2002 - Present
    Director, The Canterbury Respiratory Research Group, Christchurch, New Zealand

Research Interests

  • Asthma, allergy and airway inflammation
  • Air Pollution and airway inflammation
  • COPD
  • Alpha-1 anti-trypsin deficiency
  • Beta agonist pharmacogenetics
  • Exhaled Breath Condensate

Top 10 Publications

  • Darlow BA, Horwood LJ, Woodward LJ, Elliott JM, Troughton RW, Elder MJ, Epton MJ, Stanton JD, Swanney MP, Keenan R, Melzer TR, McKelvey VA, Levin K, Meeks MG, Espiner EA, Cameron VA, Martin J. The New Zealand 1986 very low birth weight cohort as young adults: mapping the road ahead. BMC Pediatr. 2015 Aug 5;15:90
  • Storer M, Curry K, Squire M, Kingham S, Epton M. Breath testing and personal exposure--SIFT-MS detection of breath acetonitrile for exposure monitoring. J Breath Res. 2015 May 26;9(3):036006
  • Frith PA, Thompson PJ, Ratnavadivel R, Chang CL, Bremner P, Day P, Frenzel C, Kurstjens N; Glisten Study Group. Glycopyrronium once-daily significantly improves lung function and health status when combined with salmeterol/fluticasone in patients with COPD: the GLISTEN study, a randomised controlled trial. Thorax. 2015 Jun;70(6):519-27.
  • Epton MJ, Stanton JD, McGeoch GR, Shand BI, Swanney MP. The development of a community-based spirometry service in the Canterbury region of New Zealand: observations on new service delivery. NPJ Prim Care Respir Med. 2015 Mar 5;25:15003.
  • Magnussen H, Disse B, Rodriguez-Roisin R, Kirsten A, Watz H, Tetzlaff K, Towse L, Finnigan H, Dahl R, Decramer M, Chanez P, Wouters EF, Calverley PM; WISDOM Investigators. Withdrawal of inhaled glucocorticoids and exacerbations of COPD. N Engl J Med. 2014 Oct 2;371(14):1285-94
  • Storer M., Salmond J., Dirks K.N., Kingham, S., Epton, M. Mobile selected ion flow tube mass spectrometry (SIFT-MS) devices and their use for pollution exposure monitoring in breath and ambient air-pilot study. Journal of Breath Research 2014;8(3).
  • Maze M.J., Slow S., Cumins A.M., Boon K., Goulter P., Podmore R.G., Anderson T.P., Barratt K., Young S.A., Pithie A.D., Epton M.J., Werno A.M., Chambers S.T., Murdoch D.R. Enhanced detection of Legionnaires' disease by PCR testing of induced sputum and throat swabs. European Respiratory Journal 2014;43(2):644-646.
  • Scott-Thomas A., Epton M., Chambers S. Validating a breath collection and analysis system for the new tuberculosis breath test. Journal of Breath Research 2013;7(3)
  • Sturney S.C., Storer M.K., Shaw G.M., Shaw D.E., Epton M.J. Off-line breath acetone analysis in critical illness. Journal of Breath Research 2013;7(3)
  • Scott-Thomas A., Syhre M., Epton, M., Murdoch D.R., Chambers S.T. Assessment of potential causes of falsely positive Mycobacterium tuberculosis breath test. Tuberculosis 2013;93(3):312-317
  • Dummer J., Storer M., Sturney S., Scott-Thomas A., Chambers S., Swanney M., Epton E. Quantification of hydrogen cyanide (HCN) in breath using selected ion flow tube mass spectrometry - HCN is not a biomarker of Pseudomonas in chronic suppurative lung disease. Journal of Breath Research 2013;7(1). doi:10.1088/1752-7155/7/1/017105

Publications

Zhang, X., Wilkinson, A., Storer, M., & Epton, M. J. (2023). Impact of COVID-19 and lockdown on COPD admissions to Christchurch Hospital, New Zealand 2020-2021: A combined quantitative and qualitative study. Internal Medicine Journal. Advance online publication. doi: 10.1111/imj.16204

Chambers, S. T., Scott-Thomas, A., Storer, M., Slow, S., Williman, J., Epton, M., Murdoch, D. R., Metcalf, S., Carr, A., Isenman, H., & Maze, M. (2023). Adjunctive intravenous then oral vitamin C for moderate and severe community-acquired pneumonia in hospitalized adults: Feasibility of randomized controlled trial. Scientific Reports, 13, 11879. doi: 10.1038/s41598-023-37934-z

Cameron, V. A., Jones, G. T., Horwood, L. J., Pilbrow, A. P., Martin, J., Frampton, C., Ip, W. T., Troughton, R. W., Greer, C., Yang, J., Epton, M. J., Harris, S. L., & Darlow, B. A. (2023). DNA methylation patterns at birth predict health outcomes in young adults born very low birthweight. Clinical Epigenetics, 15, 47. doi: 10.1186/s13148-023-01463-3

Cheung, J., Nordmeier, K., Kelland, S., Harrington, M., Williman, J., Storer, M., Beaglehole, B., Beckert, L., Chambers, S. T., Epton, M. J., Freeman, J., Murdoch, D. R., Werno, A. M., & Maze, M. J. (2023). Symptom persistence and recovery among COVID-19 survivors during a limited outbreak in Canterbury, New Zealand: A prospective cohort study. Internal Medicine Journal, 53, 37-45. doi: 10.1111/imj.15930

Bryce, A., Foley, L., Phillipson, J., Slow, S., Storer, M., Williman, J., Beasley, R., Bhally, H., … Dummer, J., Epton, M., … Gracie, K., Hancox, R. J., Hills, T., Hogg, S., … Kearns, N., … Murdoch, D., Raymond, N., … Maze, M. J. (2022). Clinical features of patients hospitalised with COVID-19 from February to October 2020, during the early waves of the pandemic in New Zealand. New Zealand Medical Journal, 135(1552), 120-130. Retrieved from https://journal.nzma.org.nz/

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