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Moritz LasseResearch Fellow

Diplom Biologe(Hamburg) PhD(Cant)

Email moritz.lasse@otago.ac.nz

Research interests

Moritz Lassé’s research focus is plasma proteomics.

His aim is to identify peptide and protein markers in blood that help predict future cardiovascular events in the general population or deterioration of renal function in heart failure patients.

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Publications

Lassé, M., Stampfli, A. R., Orban, T., Bothara, R. K., Gerrard, J. A., Fairbanks, A. J., … Dobson, R. C. J. (2021). Reaction dynamics and residue identification of haemoglobin modification by acrolein, a lipid-peroxidation by-product. Biochimica et Biophysica Acta: General Subjects, 1865, 130013. doi: 10.1016/j.bbagen.2021.130013

Lassé, M., Pilbrow, A. P., Kleffmann, T., Andersson Överström, E., von Zychlinski, A., Frampton, C. M. A., … Troughton, R. W., Lewis, L. K., Prickett, T. C. R., Pemberton, C. J., Richards, A. M., & Cameron, V. A. (2021). Fibrinogen and hemoglobin predict near future cardiovascular events in asymptomatic individuals. Scientific Reports, 11(1), 4605. doi: 10.1038/s41598-021-84046-7

Poen, S., Nakatani, Y., Opel-Reading, H. K., Lassé, M., Dobson, R. C. J., & Krause, K. L. (2016). Exploring the structure of glutamate racemase from Mycobacterium tuberculosis as a template for anti-mycobacterial drug discovery. Biochemical Journal, 473, 1267-1280. doi: 10.1042/bcj20160186

Lassé, M., Ulluwishewa, D., Healy, J., Thompson, D., Miller, A., Roy, N., Chitcholtan, K., & Gerrard, J. A. (2016). Evaluation of protease resistance and toxicity of amyloid-like food fibrils from whey, soy, kidney bean, and egg white. Food Chemistry, 192, 491-498. doi: 10.1016/j.foodchem.2015.07.044

Lassé, M., Deb-Choudhury, S., Haines, S., Larsen, N., Gerrard, J. A., & Dyer, J. M. (2015). The impact of pH, salt concentration and heat on digestibility and amino acid modification in egg white protein. Journal of Food Composition & Analysis, 38, 42-48. doi: 10.1016/j.jfca.2014.08.007

Lassé, M., Gerrard, J. A., & Pearce, F. G. (2012). Aggregation and fibrillogenesis of proteins not associated with disease: A few case studies. In J. R. Harris (Ed.), Protein aggregation and fibrillogenesis in cerebral and systemic amyloid disease. (pp. 253-270). Dordrecht, The Netherlands: Springer. doi: 10.1007/978-94-007-5416-4_11

Chapter in Book - Research

Lassé, M., Pilbrow, A. P., Kleffmann, T., Andersson Överström, E., von Zychlinski, A., Frampton, C. M. A., … Troughton, R. W., Lewis, L. K., Prickett, T. C. R., Pemberton, C. J., Richards, A. M., & Cameron, V. A. (2021). Fibrinogen and hemoglobin predict near future cardiovascular events in asymptomatic individuals. Scientific Reports, 11(1), 4605. doi: 10.1038/s41598-021-84046-7

Journal - Research Article

Lassé, M., Stampfli, A. R., Orban, T., Bothara, R. K., Gerrard, J. A., Fairbanks, A. J., … Dobson, R. C. J. (2021). Reaction dynamics and residue identification of haemoglobin modification by acrolein, a lipid-peroxidation by-product. Biochimica et Biophysica Acta: General Subjects, 1865, 130013. doi: 10.1016/j.bbagen.2021.130013

Journal - Research Article

Lassé, M., Ulluwishewa, D., Healy, J., Thompson, D., Miller, A., Roy, N., Chitcholtan, K., & Gerrard, J. A. (2016). Evaluation of protease resistance and toxicity of amyloid-like food fibrils from whey, soy, kidney bean, and egg white. Food Chemistry, 192, 491-498. doi: 10.1016/j.foodchem.2015.07.044

Journal - Research Article

Poen, S., Nakatani, Y., Opel-Reading, H. K., Lassé, M., Dobson, R. C. J., & Krause, K. L. (2016). Exploring the structure of glutamate racemase from Mycobacterium tuberculosis as a template for anti-mycobacterial drug discovery. Biochemical Journal, 473, 1267-1280. doi: 10.1042/bcj20160186

Journal - Research Article

Lassé, M., Deb-Choudhury, S., Haines, S., Larsen, N., Gerrard, J. A., & Dyer, J. M. (2015). The impact of pH, salt concentration and heat on digestibility and amino acid modification in egg white protein. Journal of Food Composition & Analysis, 38, 42-48. doi: 10.1016/j.jfca.2014.08.007

Journal - Research Article

Crowther, J. M., Lassé, M., Suzuki, H., Kessans, S. A., Loo, T. S., Norris, G. E., … Dobson, R. C. J. (2014). Ultra-high resolution crystal structure of recombinant caprine β-lactoglobulin. FEBS Letters, 588(21), 3816-3822. doi: 10.1016/j.febslet.2014.09.010

Journal - Research Article

Kaur, M., Healy, J., Vasudevamurthy, M., Lassé, M., Puskar, L., Tobin, M. J., … Sasso, L. (2014). Stability and cytotoxicity of crystallin amyloid nanofibrils. Nanoscale, 6(21), 13169-13178. doi: 10.1039/C4NR04624B

Journal - Research Article

Benjamin, O., Lassé, M., Silcock, P., & Everett, D. W. (2012). Effect of pectin adsorption on the hydrophobic binding sites of β-lactoglobulin in solution and in emulsion systems. International Dairy Journal, 26(1), (pp. 36-40). doi: 10.1016/j.idairyj.2011.12.007

Conference Contribution - Published proceedings: Full paper

Gerrard, J. A., Lasse, M., Cottam, J., Healy, J. P., Fayle, S. E., Rasiah, I., … Larsen, N. G. (2012). Aspects of physical and chemical alterations to proteins during food processing: Some implications for nutrition. British Journal of Nutrition, 108(Suppl. 2), (pp. S288-S297). doi: 10.1017/S000711451200236X

Conference Contribution - Published proceedings: Full paper

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