MB BS, BSc(Med), PhD, FRACP
Email zoltan.endre@otago.ac.nz
Department of Medicine
University of Otago, Christchurch
PO Box 4345
Christchurch
New Zealand
Current Roles
- Nephrologist
- Deputy Editor-in-Chief, New Zealand: Internal Medicine Journal
Research Interests
- Acute Renal Failure: Pathophysiology
- Acute Renal Failure: Early Detection - Biomarkers
- Acute Renal Failure: Apotposis, Growth Factors and Cell Survival Genes
- Acute Renal Failure: Roles of Nitric Oxide and Oxygen-derived Free Radicals
- Renal Endothelial Function: Roles of Nitric Oxide and Angiotensin II
- Renal Endothelial Function: Haemodynamics and Modelling
- Renal Endothelial Function: Progression of Renal Failure in Hypertension and Diabetes
- Renal Applications of Magnetic Resonance Spectroscopy and Imaging
Publications
Au, A. Y. M., Mantik, K., Bahadory, F., Stathakis, P., Guiney, H., Erlich, J., Walker, R., Poulton, R., … Endre, Z. H. (2023). Plasma arginine metabolites in health and chronic kidney disease. Nephrology Dialysis Transplantation, gfad108. Advance online publication. doi: 10.1093/ndt/gfad108
Templeton, E. M., Pilbrow, A. P., Kleffmann, T., Pickering, J. W., Rademaker, M. T., Scott, N. J. A., Ellmers, L. J., Charles, C. J., Endre, Z. H., Richards, A. M., Cameron, V. A., & Lassé, M. (2023). Comparison of SPEED, S-Trap, and in-solution-based sample preparation methods for mass spectrometry in kidney tissue and plasma. International Journal of Molecular Sciences, 24(7), 6290. doi: 10.3390/ijms24076290
Guiney, H., Walker, R., Broadbent, J., Caspi, A., Goodin, E., Kokaua, J., … Robertson, S., Theodore, R., Poulton, R., & Endre, Z. (2022). Kidney-function trajectories from young adulthood to midlife: Identifying risk strata and opportunities for intervention. Kidney International Reports. Advance online publication. doi: 10.1016/j.ekir.2022.10.005
Templeton, E. M., Lassé, M., Kleffmann, T., Ellmers, L. J., Palmer, S. C., Davidson, T., Scott, N. J. A., Pickering, J. W., Charles, C. J., Endre, Z. H., Cameron, V. A., Richards, A. M., Rademaker, M. T., & Pilbrow, A. P. (2022). Identifying candidate protein markers of acute kidney injury in acute decompensated heart failure. International Journal of Molecular Sciences, 23, 1009. doi: 10.3390/ijms23021009
Templeton, E., Lassé, M., Kleffmann, T., Ellmers, L. J., Palmer, S. C., Davidson, T., Scott, N. J., Pickering, J. W., Charles, C. J., Endre, Z. H., Cameron, V. A., & Richards, A. M. (2021). Identifying candidate protein markers of acute kidney injury in acute decompensated heart failure. Heart, Lung & Circulation, 30(Suppl. 2), (pp. S66). doi: 10.1016/j.hlc.2021.05.020
Endre, Z. H., & Walker, R. J. (2017). Biomarkers of cardiovascular risk in chronic kidney disease. In C. L. Edelstein (Ed.), Biomarkers of kidney disease. (2nd ed.) (pp. 485-511). London, UK: Elsevier. doi: 10.1016/B978-0-12-803014-1.00011-X
Chapter in Book - Research
Walker, R. J., & Endre, Z. H. (2013). Cellular mechanisms of drug nephrotoxicity. In R. J. Alpern, O. W. Moe & M. Caplan (Eds.), Seldin and Giebisch's the kidney: Physiology and pathophysiology (Vol. 2). (5th ed.) (pp. 2889-2932). London, UK: Academic Press. doi: 10.1016/B978-0-12-381462-3.00085-9
Chapter in Book - Research
Endre, Z. H., & Robinson, J. (2012). Water, electrolytes, and acid-based balance. In J. Mann & A. S. Truswell (Eds.), Essentials of human nutrition. (4th ed.) (pp. 125-138). Oxford University Press.
Chapter in Book - Research
Pickering, J. W., & Endre, Z. H. (2012). The metamorphosis of acute renal failure to acute kidney injury. In M. Sahay (Ed.), Basic nephrology and acute kidney injury. (pp. 125-150). Rijeka, Croatia: InTech. doi: 10.5772/1298
Chapter in Book - Research
Endre, Z. H., & Edelstein, C. L. (2008). Animal models for the assessment of acute renal dysfunction and injury. In M. E. De Broe & G. A. Porter (Eds.), Clinical nephrotoxins: Renal injury from drugs and chemicals. (3rd ed.) (pp. 173-222). US: Springer. doi: 10.1007/978-0-387-84843-3
Chapter in Book - Research
Walker, R. J., & Endre, Z. H. (2008). Cellular mechanisms of drug nephrotoxicity. In R. J. Alpern & S. C. Hebert (Eds.), Seldin and Giebisch's: The kidney: Physiology and pathophysiology (Vols. 1-2). (4th ed.) (pp. 2507-2536). Burlington, MA: Academic Press.
Chapter in Book - Research
Endre, Z. (2007). Hyponatraemia. In D. C. Harris & Colleagues (Eds.), Clinical cases in kidney disease. (pp. 3-24). Sydney, Australia: McGraw-Hill.
Chapter in Book - Research
Melnikov, V. Y., Endre, Z. H., & Edelstein, C. L. (2003). Animal models for the assessment of acute renal dysfunction and injury. In M. E. De Broe, G. A. Porter, W. M. Bennett & G. A. Verpooten (Eds.), Clinical nephrotoxins: Renal injury from drugs and chemicals. (2nd ed.) (pp. 77-114). Dordrecht, The Netherlands: Kluwer Academic.
Chapter in Book - Research
Au, A. Y. M., Mantik, K., Bahadory, F., Stathakis, P., Guiney, H., Erlich, J., Walker, R., Poulton, R., … Endre, Z. H. (2023). Plasma arginine metabolites in health and chronic kidney disease. Nephrology Dialysis Transplantation, gfad108. Advance online publication. doi: 10.1093/ndt/gfad108
Journal - Research Article
Templeton, E. M., Pilbrow, A. P., Kleffmann, T., Pickering, J. W., Rademaker, M. T., Scott, N. J. A., Ellmers, L. J., Charles, C. J., Endre, Z. H., Richards, A. M., Cameron, V. A., & Lassé, M. (2023). Comparison of SPEED, S-Trap, and in-solution-based sample preparation methods for mass spectrometry in kidney tissue and plasma. International Journal of Molecular Sciences, 24(7), 6290. doi: 10.3390/ijms24076290
Journal - Research Article
Guiney, H., Walker, R., Broadbent, J., Caspi, A., Goodin, E., Kokaua, J., … Robertson, S., Theodore, R., Poulton, R., & Endre, Z. (2022). Kidney-function trajectories from young adulthood to midlife: Identifying risk strata and opportunities for intervention. Kidney International Reports. Advance online publication. doi: 10.1016/j.ekir.2022.10.005
Journal - Research Article
Templeton, E. M., Lassé, M., Kleffmann, T., Ellmers, L. J., Palmer, S. C., Davidson, T., Scott, N. J. A., Pickering, J. W., Charles, C. J., Endre, Z. H., Cameron, V. A., Richards, A. M., Rademaker, M. T., & Pilbrow, A. P. (2022). Identifying candidate protein markers of acute kidney injury in acute decompensated heart failure. International Journal of Molecular Sciences, 23, 1009. doi: 10.3390/ijms23021009
Journal - Research Article
Rademaker, M. T., Pilbrow, A. P., Ellmers, L. J., Palmer, S. C., Davidson, T., Mbikou, P., Scott, N. J. A., Permina, E., Charles, C. J., Endre, Z. H., & Richards, A. M. (2021). Acute decompensated heart failure and the kidney: Physiological, histological and transcriptomic responses to development and recovery. Journal of the American Heart Association, 10, e021312. doi: 10.1161/jaha.121.021312
Journal - Research Article
Mohamed, F., Buckley, N. A., Pickering, J. W., Wunnapuk, K., Dissanayake, S., Chathuranga, U., … Endre, Z. H. (2017). Nephrotoxicity-induced proteinuria increases biomarker diagnostic thresholds in acute kidney injury. BMC Nephrology, 18(1), 122. doi: 10.1186/s12882-017-0532-7
Journal - Research Article
Pianta, T. J., Pickering, J. W., Succar, L., Chin, M., Davidson, T., Buckley, N. A., … Endre, Z. H. (2017). Dexamethasone modifies cystatin C-based diagnosis of acute kidney injury during cisplatin-based chemotherapy. Kidney & Blood Pressure Research, 62-75. doi: 10.1159/000469715
Journal - Research Article
Puckett, J. R., Pickering, J. W., Palmer, S. C., McCall, J. L., Kluger, M. T., De Zoysa, J., Endre, Z. H., & Soop, M. (2017). Low versus standard urine output targets in patients undergoing major abdominal surgery: A randomized noninferiority trial. Annals of Surgery, 265(5), 874-881. doi: 10.1097/sla.0000000000002044
Journal - Research Article
Succar, L., Pianta, T. J., Davidson, T., Pickering, J. W., & Endre, Z. H. (2017). Subclinical chronic kidney disease modifies the diagnosis of experimental acute kidney injury. Kidney International, 92(3), 680-692. doi: 10.1016/j.kint.2017.02.030
Journal - Research Article
Teo, S. H., & Endre, Z. H. (2017). Biomarkers in acute kidney injury (AKI). Best Practice & Research: Clinical Anaesthesiology, 31(3), 331-344. doi: 10.1016/j.bpa.2017.10.003
Journal - Research Article
Endre, Z. H., Pianta, T. J., & Pickering, J. W. (2016). Timely diagnosis of acute kidney injury using kinetic eGFR and the creatinine excretion to production ratio, E/eG: Creatinine can be useful! Nephron Clinical Practice, 132, 312-316. doi: 10.1159/000444456
Journal - Research Article
Mohamed, F., Endre, Z. H., Pickering, J. W., Jayamanne, S., Palangasinghe, C., Shahmy, S., … Buckley, N. A. (2016). Mechanism-specific injury biomarkers predict nephrotoxicity early following glyphosate surfactant herbicide (GPSH) poisoning. Toxicology Letters, 258, 1-10. doi: 10.1016/j.toxlet.2016.06.001
Journal - Research Article
Pickering, J. W., & Endre, Z. H. (2016). Bench to bedside: The next steps for biomarkers in acute kidney injury. American Journal of Physiology: Renal Physiology, 311(4), F717-F721. doi: 10.1152/ajprenal.00268.2016
Journal - Research Article
Wang, M. H., Chong, K. C., Storer, M., Pickering, J. W., Endre, Z. H., Lau, S. Y. F., … Zee, B. C. Y. (2016). Use of a least absolute shrinkage and selection operator (LASSO) model to selected ion flow tube mass spectrometry (SIFT-MS) analysis of exhaled breath to predict the efficacy of dialysis: A pilot study. Journal of Breath Research, 10(4), 046004. doi: 10.1088/1752-7155/10/4/046004
Journal - Research Article
Chew-Harris, J. S. C., Chin, P. K. L., Florkowski, C. M., George, P., & Endre, Z. (2015). Removal of body surface area normalisation improves raw-measured glomerular filtration rate estimation by the Chronic Kidney Disease Epidemiology Collaboration equation and drug dosing in the obese. Internal Medicine Journal, 45(7), 766-773. doi: 10.1111/imj.12791
Journal - Research Article
Chew-Harris, J. S. C., Florkowski, C. M., George, P. M., & Endre, Z. H. (2015). Comparative performances of the new chronic kidney disease epidemiology equations incorporating cystatin C for use in cancer patients. Asia-Pacific Journal of Clinical Oncology, 11(2), 142-151. doi: 10.1111/ajco.12312
Journal - Research Article
Mohamed, F., Buckley, N. A., Jayamanne, S., Pickering, J. W., Peake, P., Palangasinghe, C., … Endre, Z. H. (2015). Kidney damage biomarkers detect acute kidney injury but only functional markers predict mortality after paraquat ingestion. Toxicology Letters, 237(2), 140-150. doi: 10.1016/j.toxlet.2015.06.008
Journal - Research Article
Pianta, T. J., Endre, Z. H., Pickering, J. W., Buckley, N. A., & Peake, P. W. (2015). Kinetic estimation of GFR improves prediction of dialysis and recovery after kidney transplantation. PLoS ONE, 10(5), e0125669. doi: 10.1371/journal.pone.0125669
Journal - Research Article
Pianta, T. J., Peake, P. W., Pickering, J. W., Kelleher, M., Buckley, N. A., & Endre, Z. H. (2015). Evaluation of biomarkers of cell cycle arrest and inflammation in prediction of dialysis or recovery after kidney transplantation. Transplant International, 28(12), 1392-1404. doi: 10.1111/tri.12636
Journal - Research Article
Pianta, T. J., Peake, P. W., Pickering, J. W., Kelleher, M., Buckley, N. A., & Endre, Z. H. (2015). Clusterin in kidney transplantation: Novel biomarkers versus serum creatinine for early prediction of delayed graft function. Transplantation, 99(1), 171-179. doi: 10.1097/tp.0000000000000256
Journal - Research Article
Takaki, S., Shehabi, Y., Pickering, J. W., Endre, Z., Miyashita, T., & Goto, T. (2015). Perioperative change in creatinine following cardiac surgery with cardiopulmonary bypass is useful in predicting acute kidney injury: A single-centre retrospective cohort study. Interactive Cardiovascular & Thoracic Surgery, 21(4), 465-469. doi: 10.1093/icvts/ivv184
Journal - Research Article
Chew-Harris, J. S. C., Florkowski, C. M., Elmslie, J. L., Livesey, J., Endre, Z. H., & George, P. M. (2014). Lean mass modulates glomerular filtration rate in males of normal and extreme body composition. Internal Medicine Journal, 44(8), 749-756. doi: 10.1111/imj.12479
Journal - Research Article
Endre, Z. H. (2014). Using biomarkers for acute kidney injury: Barriers and solutions. Nephron Clinical Practice, 127(1-4), 180-184. doi: 10.1159/000363555
Journal - Research Article
Pickering, J. W., & Endre, Z. H. (2014). Acute kidney injury urinary biomarker time-courses. PLoS ONE, 9(7), e101288. doi: 10.1371/journal.pone.0101288
Journal - Research Article
Ralib, A. M., Pickering, J. W., Shaw, G. M., Than, M. P., George, P. M., & Endre, Z. H. (2014). The clinical utility window for acute kidney injury biomarkers in the critically ill. Critical Care, 18, 601. doi: 10.1186/s13054-014-0601-2
Journal - Research Article
Chew-Harris, J. S. C., Florkowski, C. M., George, P. M., Elmslie, J. L., & Endre, Z. H. (2013). The relative effects of fat versus muscle mass on cystatin C and estimates of renal function in healthy young men. Annals of Clinical Biochemistry, 50(1), 39-46. doi: 10.1258/acb.2012.011241
Journal - Research Article
Endre, Z. H., & Pickering, J. W. (2013). Acute kidney injury clinical trial design: Old problems, new strategies. Pediatric Nephrology, 28(2), 207-217. doi: 10.1007/s00467-012-2171-3
Journal - Research Article
Md Ralib, A., Pickering, J. W., Shaw, G. M., & Endre, Z. H. (2013). The urine output definition of acute kidney injury is too liberal. Critical Care, 17, R112. doi: 10.1186/cc12784
Journal - Research Article
Pianta, T. J., Buckley, N. A., Peake, P., & Endre, Z. H. (2013). Clinical use of biomarkers for toxicant-induced acute kidney injury. Biomarkers in Medicine, 7(3), 441-456. doi: 10.2217/bmm.13.51
Journal - Research Article
Pickering, J. W., & Endre, Z. H. (2013). Linking injury to outcome in acute kidney injury: A matter of sensitivity. PLoS ONE, 8(4), e62691. doi: 10.1371/journal.pone.0062691
Journal - Research Article
Pickering, J. W., & Endre, Z. H. (2013). The clinical utility of plasma neutrophil gelatinase-associated lipocalin in acute kidney injury. Blood Purification, 35(4), 295-302. doi: 10.1159/000351542
Journal - Research Article
Pickering, J. W., Ralib, A. M., & Endre, Z. H. (2013). Combining creatinine and volume kinetics identifies missed cases of acute kidney injury following cardiac arrest. Critical Care, 17, R7. doi: 10.1186/cc11931
Journal - Research Article
Ralib, A. M., Pickering, J. W., Major, T., Palmer, S. C., Shaw, G. M., Goodkin, D. A., & Endre, Z. H. (2013). High-dose intravenous epoetin does not increase blood pressure in critically ill patients with acute kidney injury. Clinical Nephrology, 79(5), 370-379. doi: 10.5414/cn107673
Journal - Research Article
Md Ralib, A., Pickering, J. W., Shaw, G. M., Devarajan, P., Edelstein, C. L., Bonventre, J. V., & Endre, Z. H. (2012). Test characteristics of urinary biomarkers depend on quantitation method in acute kidney injury. Journal of the American Society of Nephrology, 23(2), 322-333. doi: 10.1681/asn.2011040325
Journal - Research Article
Nejat, M., Hill, J. V., Pickering, J. W., Edelstein, C. L., Devarajan, P., & Endre, Z. H. (2012). Albuminuria increases cystatin C excretion: Implications for urinary biomarkers. Nephrology Dialysis Transplantation, 27(Suppl. 3), iii96-iii103. doi: 10.1093/ndt/gfr222
Journal - Research Article
Nejat, M., Pickering, J. W., Devarajan, P., Bonventre, J. V., Edelstein, C. L., Walker, R. J., & Endre, Z. H. (2012). Some biomarkers of acute kidney injury are increased in pre-renal acute injury. Kidney International, 81, 1254-1262. doi: 10.1038/ki.2012.23
Journal - Research Article
Pickering, J. W., & Endre, Z. H. (2012). Challenges facing early detection of acute kidney injury in the critically ill. World Journal of Critical Care Medicine, 1(3), 61-66. doi: 10.5492/wjccm.v1.i3.61
Journal - Research Article
Pickering, J. W., & Endre, Z. H. (2012). New metrics for assessing diagnostic potential of candidate biomarkers. Clinical Journal of the American Society of Nephrology, 7(8), 1355-1364. doi: 10.2215/cjn.09590911
Journal - Research Article
Pickering, J. W., Frampton, C. M., Walker, R. J., Shaw, G. M., & Endre, Z. H. (2012). Four hour creatinine clearance is better than plasma creatinine for monitoring renal function in critically ill patients. Critical Care, 16, R107. doi: 10.1186/cc11391
Journal - Research Article
Endre, Z. H., & Pickering, J. W. (2011). New markers of acute kidney injury: Giant leaps and baby steps. Clinical Biochemist Reviews, 32(2), 121-124.
Journal - Research Article
Endre, Z. H., Pickering, J. W., & Walker, R. J. (2011). Clearance and beyond: The complementary roles of GFR measurement and injury biomarkers in acute kidney injury (AKI). American Journal of Physiology: Renal Physiology, 301(4), F697-F707. doi: 10.1152/ajprenal.00448.2010
Journal - Research Article
Endre, Z. H., Pickering, J. W., Walker, R. J., Devarajan, P., Edelstein, C. L., Bonventre, J. V., Frampton, C. M., … Shaw, G. M., Henderson, S. J., Nejat, M., Schollum, J. B. W., & George, P. M. (2011). Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney International, 79, 1119-1130. doi: 10.1038/ki.2010.555
Journal - Research Article