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Dr Barry R Palmer

Barry Palmer

BSc(Hons) PhD(Otago)

Email barry.palmer@otago.ac.nz

Department of Medicine
University of Otago, Christchurch
PO Box 4345
Christchurch
New Zealand

Background

Dr Barry Palmer completed his PhD in Microbial Genetics at the University of Otago in 1988, on the topic of Restriction mapping of FP2, a conjugative plasmid of Pseudomonas aeruginosa.

He had postdoctoral training at the University of Massachusetts Medical School, Worcester, Massachusetts in 1988-90 specialising in DNA methylation and DNA repair in Escherichia coli.

On returning to New Zealand Barry lectured in Molecular Biology in the Department of Plant and Microbial Sciences at the University of Canterbury from 1990-94 and undertook research into the molecular genetics of Pseudomonas aeruginosa and Escherichia coli.

From 1994-2000 he was a Research Officer in the Animal and Food Sciences Division at the Lincoln University investigating the use of genetic markers to improve meat quality and yield in sheep.

Dr Palmer's recent genotyping projects at the Christchurch Heart Institute have included:

  • Gene variants from the human X-chromosome as prognostic markers in coronary heart disease
  • The VEGF system and survival in coronary heart disease

Current Roles

Research Interests

  • Human Molecular Genetics
  • Genetics of the X-chromosome
  • Animal Molecular Genetics
  • Molecular Microbiology

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Publications

Palmer, B. R., Pilbrow, A. P., Yandle, T. G., Frampton, C. M., Richards, A. M., Nicholls, M. G., & Cameron, V. A. (2003). Angiotensin-converting enzyme gene polymorphism interacts with left ventricular ejection fraction and brain natriuretic peptide levels to predict mortality after myocardial infarction. JACC, 41(5), 729-736. doi: 10.1016/S0735-1097(02)02927-3

Palmer, B. R., & Marinus, M. G. (1994). The dam and dcm strains of Escherichia coli: A review. Gene, 143(1), 1-12.

Palmer, B. R., Pilbrow, A. P., Frampton, C. M., Yandle, T. G., Skelton, L., Nicholls, M. G., & Richards, A. M. (2008). Plasma aldosterone levels during hospitalization are predictive of survival post-myocardial infarction. European Heart Journal, 29, 2489-2496. doi: 10.1093/eurheartj/ehn383

Palmer, B. R., Devereaux, C. L., Dhamrait, S. S., Mocatta, T. J., Pilbrow, A. P., Frampton, C. M., Skelton, L., Yandle, T. G., Winterbourn, C. C., Richards, A. M., … Cameron, V. A. (2009). The common G-866A polymorphism of the UCP2 gene and survival in diabetic patients following myocardial infarction. Cardiovascular Diabetology, 8. doi: 10.1186/1475-2840-8-31

Palmer, B. R., Jarvis, M. D., Pilbrow, A. P., Ellis, K. L., Frampton, C. M., Skelton, L., Yandle, T. G., … Whalley, G. A., … Troughton, R. W., Richards, A. M., & Cameron, V. A. (2008). Angiotensin-converting enzyme 2 A1075G polymorphism is associated with survival in an acute coronary syndromes cohort. American Heart Journal, 156(4), 752-758. doi: 10.1016/j.ahj.2008.06.013

Journal - Research Article

Palmer, B. R., Frampton, C. M., Skelton, L., Yandle, T. G., Doughty, R. N., Whalley, G. A., … Troughton, R. W., Richards, A. M., & Cameron, V. A. (2012). KCNE5 polymorphism rs697829 is associated with QT interval and survival in acute coronary syndromes patients. Journal of Cardiovascular Electrophysiology, 23(3), 319-324. doi: 10.1111/j.1540-8167.2011.02192.x

Ellis, K. L., Palmer, B. R., Frampton, C. M., Troughton, R. W., Doughty, R. N., Whalley, G. A., … Pilbrow, A. P., Skelton, L., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2012). Genetic variation in the renin-angiotensin-aldosterone system is associated with cardiovascular risk factors and early mortality in established coronary heart disease. Journal of Human Hypertension, 27, 237-244. doi: 10.1038/jhh.2012.24

Jarvis, M. D., Palmer, B. R., Pilbrow, A. P., Ellis, K. L., Frampton, C. M., Skelton, L., … Whalley, G. A., … Yandle, T. G., Richards, A. M., & Cameron, V. A. (2010). CYP1A1 MSPI (T6235C) gene polymorphism is associated with mortality in acute coronary syndrome patients. Clinical & Experimental Pharmacology & Physiology, 37(2), 193-198. doi: 10.1111/j.1440-1681.2009.05261.x

Ellis, K. L., Pilbrow, A. P., Frampton, C. M., Doughty, R. N., Whalley, G. A., Ellis, C. J., Palmer, B. R., Skelton, L., Yandle, T. G., Palmer, S. C., Troughton, R. W., Richards, A. M., & Cameron, V. A. (2010). A common variant at chromosome 9P21.3 is associated with age of onset of coronary disease but not subsequent mortality. Circulation: Cardiovascular Genetics, 3(3), 286-293. doi: 10.1161/circgenetics.109.917443

Palmer, B. R., Devereaux, C. L., Dhamrait, S. S., Mocatta, T. J., Pilbrow, A. P., Frampton, C. M., Skelton, L., Yandle, T. G., Winterbourn, C. C., Richards, A. M., … Cameron, V. A. (2009). The common G-866A polymorphism of the UCP2 gene and survival in diabetic patients following myocardial infarction. Cardiovascular Diabetology, 8. doi: 10.1186/1475-2840-8-31

Palmer, B. R., Pilbrow, A. P., Frampton, C. M., Yandle, T. G., Skelton, L., Nicholls, M. G., & Richards, A. M. (2008). Plasma aldosterone levels during hospitalization are predictive of survival post-myocardial infarction. European Heart Journal, 29, 2489-2496. doi: 10.1093/eurheartj/ehn383

Palmer, B. R., Jarvis, M. D., Pilbrow, A. P., Ellis, K. L., Frampton, C. M., Skelton, L., Yandle, T. G., … Whalley, G. A., … Troughton, R. W., Richards, A. M., & Cameron, V. A. (2008). Angiotensin-converting enzyme 2 A1075G polymorphism is associated with survival in an acute coronary syndromes cohort. American Heart Journal, 156(4), 752-758. doi: 10.1016/j.ahj.2008.06.013

Littlejohn, M. D., Palmer, B. R., Richards, A. M., Frampton, C. M., Pilbrow, A. P., Troughton, R. W., Cameron, V. A., & Kennedy, M. A. (2008). Ile164 variant of β2-adrenoceptor does not influence outcome in heart failure but may interact with β blocker treatment. European Journal of Heart Failure, 10(1), 55-59. doi: 10.1016/j.ejheart.2007.10.011

Baird, T. E., Palmer, B. R., Frampton, C. M., Yandle, T. G., Skelton, L., Richards, A. M., & Cameron, V. A. (2007). Association of the aldosterone synthase gene C-344T polymorphism with risk factors and survival in a post-myocardial infarction cohort. Journal of Human Hypertension, 21, 256-258.

Pilbrow, A. P., Palmer, B. R., Frampton, C. M., Yandle, T. G., Troughton, R. W., Campbell, E., Skelton, L., Lainchbury, J. G., Richards, A. M., & Cameron, V. A. (2007). Angiotensinogen M235T and T174M gene polymorphisms in combination doubles the risk of mortality in heart failure. Hypertension, 49(2), 322-327.

Jarvis, M. D., Rademaker, M. T., Ellmers, L. J., Currie, M. J., McKenzie, J. L., Palmer, B. R., Frampton, C. M., Richards, A. M., & Cameron, V. A. (2006). Comparison of infarct-derived and control ovine cardiac myofibroblasts in culture: Response to cytokines and natriuretic peptide receptor expression profiles. American Journal of Physiology: Heart & Circulatory Physiology, 291, H1952-H1958. doi: 10.1152/ajpheart.00764.2005

Collins, R. P., Palmer, B. R., Pilbrow, A. P., Frampton, C. M., Troughton, R. W., Yandle, T. G., Skelton, L., Richards, A. M., & Cameron, V. A. (2006). Evaluation of AMPD1 C34T genotype as a predictor of mortality in heart failure and post-myocardial infarction patients. American Heart Journal, 152(2), 312-320.

Palmer, B. R., Pilbrow, A. P., Yandle, T. G., Frampton, C. M., Richards, A. M., Nicholls, M. G., & Cameron, V. A. (2003). Angiotensin-converting enzyme gene polymorphism interacts with left ventricular ejection fraction and brain natriuretic peptide levels to predict mortality after myocardial infarction. JACC, 41(5), 729-736. doi: 10.1016/S0735-1097(02)02927-3

Cameron, V. A., & Palmer, B. R. (2003). Reply to letter to the editor Angiotensin-converting enzyme polymorphism (I/D) and coronary heart disease in young adults. JACC, 42(10), 1864.

Ilian, M. A., Morton, J. D., Bekhit, A. E.-D., Roberts, N., Palmer, B. R., Sorimachi, H., & Bickerstaffe, R. (2001). Effect of preslaughter feed withdrawal period on longissimus tenderness and the expression of calpains in the ovine. Journal of Agricultural & Food Chemistry, 49(4), 1990-1998.

Su, H.-Y., Palmer, B. R., Wellby, M. P., Bickerstaffe, R., & Hickford, J. G. H. (2001). Differential expression of a gene homologous to a G-α protein gene in neonatal mouse skin during development of hair follicles. Journal of Dermatological Science, 25(1), 10-19.

Palmer, B. R., Su, H.-Y., Roberts, N., Hickford, J. G. H., & Bickerstaffe, R. (2000). Single nucleotide polymorphisms in an intron of the ovine calpastatin gene. Animal Biotechnology, 11(1), 63-67.

Palmer, B. R., Roberts, N., Hickford, J. G. H., & Bickerstaffe, R. (1998). PCR-RFLPs for MspI and NcoI in the ovine calpastatin gene. Journal of Animal Science, 76, 1499-1500.

Wu, R., Palmer, B. R., & Cole, A. L. J. (1998). Phenotypic variation and survival of genetically marked Pseudomonas tolaasii in mushroom compost. Canadian Journal of Microbiology, 44(4), 373-377.

Palmer, B. R., & Marinus, M. G. (1994). The dam and dcm strains of Escherichia coli: A review. Gene, 143(1), 1-12.

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Journal - Research Other

Palmer, B. R., Frampton, C. M., Richards, A. M., & Cameron, V. A. (2007). AMPD1 gene polymorphism and survival in patients with stable congestive heart failure [Letter to the editor]. American Heart Journal, 153, e13. Retrieved from http://www.sciencedirect.com/science?_ob=PublicationURL&_tockey=%23TOC%236683%232007%23998469994%23650294%23FLA%23&_cdi=6683&_pubType=J&_auth=y&_acct=C000007718&_version=1&_urlVersion=0&_userid=100241&md5=724a2d0db54e3f555bbfcbe8269e42c5

Palmer, B. R., Frampton, C. M., Richards, A. M., Cameron, V. A., & Nakayama, T. (2004). Absence of a NPR-A gene functional deletion allele in a postmyocardial infarction cohort from New Zealand [Letter to the editor]. Circulation Research, 94(10), e86.

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