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Dr John N. Fink

MB ChB(Otago) FRACP

Email john.fink@cdhb.govt.nz

Department of Neurology
Christchurch Hospital
Private Bag 4710
Christchurch
New Zealand

Current Roles

  • Clinical Senior Lecturer, Department of Medicine
  • Christchurch Brain Research Group Coordinating Committee Member and Christchurch Brain Research Institute Establishment Committee Member
  • Canterbury Medical Research Society Executive Committee Member
  • Director of Basic Physician Training, Christchurch Hospital
  • Senior Fellow, Department of Mechanical Engineering, University of Canterbury

Research Interests

  • Acute Stroke Imaging and Thrombolysis
  • Cerebral Perfusion
  • Circle of Willis Haemodynamics
  • Stroke Units

Top 10 Publications

  • Fink, J.N., Kumar, S., Horkan, C., Linfante, I., Caplan, L.R., Schlaug, G. The stroke patient who woke up: clinical and radiological features, including diffusion and perfusion MRI. Stroke 33: 988-993 (2002)
  • Selim, M., Fink, J., Kumar, S., Caplan, L.R., Horkan, C., Chen, Y., Linfante, I., Schlaug, G. Predictors of hemorrhagic transformation after intravenous recombinant tissue plasminogen activator: prognostic value of the initial apparent diffusion coefficient and diffusion-weighted lesion volume. Stroke 33: 2047-2052 (2002)
  • Fink, J.N., Selim, M., Kumar, S., Silver, B., Linfante, I., Caplan, L.R., Schlaug G. Is the association of NIHSS scores and acute MRI volume equal for patients with right and left-hemisphere ischemic stroke? Stroke 33: 954-958 (2002)
  • Selim, M., Fink, J., Linfante, I., Kumar, S., Schlaug, G., Caplan, L.R. Diagnosis of cerebral venous thrombosis with echo-planar T2*-weighted magnetic resonance imaging. Archives of Neurology 59:1021-1026 (2002)
  • Selim, M., Kumar, S., Fink, J., Schlaug, G., Caplan, L.R., Linfante, I. Seizure at stroke onset: should it be an absolute contraindication to thrombolysis? Cerebrovascular Diseases 14:54-57 (2002)
  • Fink, J.N., McAuley, D.L. Mastoid air sinus abnormalities associated with lateral venous sinus thrombosis: cause or consequence? Stroke 33:290-292 (2002)
  • Fink, J.N., McAuley, D.L. Safety of anticoagulation for cerebral venous thrombosis associated with intracerebral hematoma. Neurology 57:1138-1139 (2001)
  • Fink, J.N. Localization of the “sneeze center”. Neurology 56:138 (2001)
  • Fink J.N., Caplan L.R. The importance of specific diagnosis in stroke patient management. In: Magnetic Resonance Imaging in Stroke. Davis S., Fisher M., Warach S. eds. Cambridge. Cambridge University Press (2003) 1-14.
  • Fink J.N., Caplan L.R. Cerebrovascular Cases. The Medical Clinics of North America 87:755-770 (2003)

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Publications

Langton Burnell, A., Ranta, A., Wu, T., Fink, J., McGuinness, B., Caldwell, J., Collecutt, W., … Barber, P. A. (2018). Endovascular clot retrieval for acute ischaemic stroke in New Zealand. New Zealand Medical Journal, 131(1484), 13-18. Retrieved from https://www.nzma.org.nz/journal

Wu, T., Coleman, E., Wright, S. L., Mason, D. F., Reimers, J., Duncan, R., … Hurrell, M., … Fink, J. N. (2018). Helsinki stroke model Is transferrable with “real-world” resources and reduced stroke thrombolysis delay to 34 min in Christchurch. Frontiers in Neurology, 9, 290. doi: 10.3389/fneur.2018.00290

Joshi, P., Fink, J., Barber, P. A., Davis, A., Lanford, J., Seymour, A., … Busby, W., … Ranta, A. (2016). Stroke thrombolysis in New Zealand: Data from the first 6 months of the New Zealand Thrombolysis Register. New Zealand Medical Journal, 129(1438), 42-47. Retrieved from https://www.nzma.org.nz/journal

Joshi, P., Fink, J., Barber, P. A., Davis, A., Lanford, J., Wright, P., … Ranta, A. (2016). New Zealand stroke thrombolysis: Comprehensive national data from a newly implemented mandatory national registry. Cerebrovascular Diseases, 42(Suppl. 1), (pp. 31-32). doi: 10.1159/000447732

Brownlee, W., Ranta, A., Dale-Gandar, J., Bennett, P., Gommans, J., Fink, J., & Barber, P. A. (2014). Changes in the provision of transient ischaemic attack services in New Zealand 2008 to 2013. New Zealand Medical Journal, 127(1390). Retrieved from http://www.nzma.org.nz/journal

Authored Book - Other

Gommans, J., Barber, P. A., & Fink, J. (2008). For the assessment and management of people with recent Transient Ischaemic Attack (TIA). Wellington, New Zealand: Stroke Foundation of New Zealand, 37p.

McAlister, H., Fink, J., Wilkinson, T., & et al (2005). The management of people with atrial fibrillation and flutter: Evidence-based best practice guideline. Wellington, New Zealand: New Zealand Guidelines Group. Retrieved from http://www.nzgg.org.nz

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Chapter in Book - Research

Fink, J. N., & Caplan, L. R. (2003). The importance of specific diagnosis in stroke patient management. In S. Davis, M. Fisher & S. Warach (Eds.), Magnetic resonance imaging in stroke. (pp. 1-14). Cambridge University Press.

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Journal - Research Article

Langton Burnell, A., Ranta, A., Wu, T., Fink, J., McGuinness, B., Caldwell, J., Collecutt, W., … Barber, P. A. (2018). Endovascular clot retrieval for acute ischaemic stroke in New Zealand. New Zealand Medical Journal, 131(1484), 13-18. Retrieved from https://www.nzma.org.nz/journal

Wu, T., Coleman, E., Wright, S. L., Mason, D. F., Reimers, J., Duncan, R., … Hurrell, M., … Fink, J. N. (2018). Helsinki stroke model Is transferrable with “real-world” resources and reduced stroke thrombolysis delay to 34 min in Christchurch. Frontiers in Neurology, 9, 290. doi: 10.3389/fneur.2018.00290

Joshi, P., Fink, J., Barber, P. A., Davis, A., Lanford, J., Seymour, A., … Busby, W., … Ranta, A. (2016). Stroke thrombolysis in New Zealand: Data from the first 6 months of the New Zealand Thrombolysis Register. New Zealand Medical Journal, 129(1438), 42-47. Retrieved from https://www.nzma.org.nz/journal

Brownlee, W., Ranta, A., Dale-Gandar, J., Bennett, P., Gommans, J., Fink, J., & Barber, P. A. (2014). Changes in the provision of transient ischaemic attack services in New Zealand 2008 to 2013. New Zealand Medical Journal, 127(1390). Retrieved from http://www.nzma.org.nz/journal

Child, N., Fink, J., Jones, S., Voges, K., Vivian, M., & Barber, P. A. (2012). New Zealand National Acute Stroke Services Audit: Acute stroke care delivery in New Zealand. New Zealand Medical Journal, 125(1358). Retrieved from http://www.nzma.org.nz/journal

Child, N., Barber, P. A., Fink, J., Jones, S., Voges, K., & Vivian, M. (2011). New Zealand National Acute Stroke Services Audit 2009: Organisation of acute stroke services in New Zealand. New Zealand Medical Journal, 124(1340). Retrieved from http://journal.nzma.org.nz/journal/124-1340/4810/content.pdf

Lever, M., George, P. M., Slow, S., Elmslie, J. L., Scott, R. S., Richards, A. M., Fink, J. N., & Chambers, S. T. (2009). Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine. Cardiovascular Drugs & Therapy, 23(5), 395-401. doi: 10.1007/s10557-009-6188-1

De Silva, D. A., Fink, J. N., Christensen, S., Ebinger, M., Bladin, C., Levi, C. R., … EPITHET Investigators. (2009). Assessing reperfusion and recanalization as markers of clinical outcomes after intravenous thrombolysis in the echoplanar imaging thrombolytic evaluation trial (EPITHET). Stroke, 40(8), 2872-2874. doi: 10.1161/STROKEAHA.108.543595

Barber, P. A., Gommans, J., Fink, J., Hanger, H. C., Bennett, P., & Ataman, N. (2008). Acute stroke services in New Zealand: Changes between 2001 and 2007. New Zealand Medical Journal, 121(1285). Retrieved from http://journal.nzma.org.nz/journal/121-1285/3343/content.pdf

McKinlay, A., Kaller, C. P., Grace, R. C., Dalrymple-Alford, J. C., Anderson, T. J., Fink, J., & Roger, D. (2008). Planning in Parkinson's disease: A matter of problem structure? Neuropsychologia, 46(1), 384-389. doi: 10.1016/j.neuropsychologia.2007.08.018

McKinlay, A., Grace, R. C., Dalrymple-Alford, J. C., Anderson, T., Fink, J., & Roger, D. (2008). Neuropsychiatric problems in Parkinson's disease: Comparisons between self and caregiver report. Aging & Mental Health, 12(5), 647-653.

McKinlay, A., Grace, R. C., Dalrymple-Alford, J. C., Anderson, T., Fink, J., & Roger, D. (2008). A profile of neuropsychiatric problems and their relationship to quality of life for Parkinson's disease patients without dementia. Parkinsonism & Related Disorders, 14(1), 37-42. doi: 10.1016/j.parkreldis.2007.05.009

Amadeus Investigators, including Fink, J. (2008). Comparison of idraparinux with vitamin K antagonists for prevention of thromboembolism in patients with atrial fibrillation: A randomised, open-label, non-inferiority trial. Lancet, 371, 315-321. doi: 10.1016/S0140-6736(08)60168-3

Fink, J. N., Frampton, C. M., Lyden, P., Lees, K. R., on behalf of the VISTA Investigators. (2008). Does hemispheric lateralization influence functional and cardiovascular outcomes after stroke? An analysis of placebo-treated patients from prospective acute stroke trials. Stroke, 39(12), 3335-3340. doi: 10.1161/STROKEAHA.108.523365

Davis, S. M., Donnan, G. A., Parsons, M. W., Levi, C., Butcher, K. S., Peeters, A., … Fink, J. N., … EPITHET Investigators. (2008). Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): A placebo-controlled randomised trial. Lancet Neurology, 7(4), 299-309. doi: 10.1016/S1474-4422(08)70044-9

Chao, C.-Y., Florkowski, C. M., Fink, J. N., Southby, S. J., & George, P. M. (2007). Prospective validation of cerebrospinal fluid bilirubin in suspected subarachnoid haemorrhage. Annals of Clinical Biochemistry, 44(2), 140-144. doi: 10.1258/000456307780117966

Hanger, C., Fletcher, V., Fink, J., Sidwell, A., & Roche, A. (2007). Improving care to stroke patients: Adding an acute stroke unit helps. New Zealand Medical Journal, 120(1250). Retrieved from http://journal.nzma.org.nz/journal/120-1250/2450/content.pdf

Moore, S., David, T., Chase, J. G., Arnold, J., & Fink, J. (2006). 3D models of blood flow in the cerebral vasculature. Journal of Biomechanics, 39, 1454-1463.

Anderson, N. E., Mason, D. F., Fink, J. N., Bergin, P. S., Charleston, A. J., & Gamble, G. D. (2005). Detection of focal cerebral hemisphere lesions using the neurological examination. Journal of Neurology, Neurosurgery & Psychiatry, 76, 545-549.

Butcher, K. S., Parsons, M., MacGregor, L., Barber, P. A., . . ., Fink, J., & ... (2005). Refining the perfusion-diffusion mismatch hypothesis. Stroke, 36(6), 1153-1159.

Moorhead, K. T., Moore, S. M., Chase, J. G., David, T., & Fink, J. (2005). Impact of decentralised control in cerebral blood flow auto-regulation using 1D and 3D models. International Journal of Intelligent Systems Technologies & Applications, 1(1-2), 95-110.

Fink, J. (2005). Twelve-month experience of acute stroke thrombolysis in Christchurch, New Zealand: Emergency department screening and acute stroke service treatment. New Zealand Medical Journal, 118(1214). Retrieved from http://journal.nzma.org.nz/journal/118-1214/1430/content.pdf

Moore, S. M., Moorhead, K. T., Chase, J. G., David, T., & Fink, J. (2005). One-dimensional and three-dimensional models of cerebrovascular flow. Journal of Biomechanical Engineering, 127(3), 440-449.

Fink, J. N., Selim, M. H., Kumar, S., Voetsch, B., Fong, W. C., & Caplan, L. R. (2005). Insular cortex infarction in acute middle cerebral artery territory stroke: Predictor of stroke severity and vascular lesion. Archives of Neurology, 62(7), 1081-1085.

Selim, M. H., Fink, J. N., Kumara, S., Caplan, L. R., Horkan, C., Chen, Y., … Schlaug, G. (2002). Predictors of hemorrhagic transformation after intravenous recombinant tissue plasminogen activator: Prognostic value of initial apparent diffusion coefficient and diffusion-weighted lesion volume. Stroke, 33, 2047-2052.

Fink, J. N., Selim, M. H., Kumar, S., Silver, B., Linfante, I., Caplan, L. R., & Schlaug, G. (2002). Is the association of NIHSS scores and acute MRI stroke volume equal for patients with right - and left - hemisphere ischemic stroke? Stroke, 33, 954-958.

Selim, M. H., Fink, J. N., Linfante, I., Kumara, S., Schlaug, G., & Caplan, L. R. (2002). Diagnosis of cerebral venous thrombosis with echo-planar T2*-weighted magnetic resonance imaging. Archives of Neurology, 59, 1021-1026.

Fink, J. N., Selim, M. H., Kumara, S., Silver, B., Linfante, I., & Caplan, L. R. (2002). Is the association of NIHSS scores and acute MRI volume equal for patients with right and left- hemisphere ischemic stroke? Stroke, 33, 954-958.

Fink, J. N., & McAuley, D. L. (2002). Mastoid air sinus abnormalities associated with lateral venous sinus thrombosis: Cause or consequence? Stroke, 33, 290-292.

Selim, M. H., Fink, J. N., Kumar, S., Caplan, L. R., Horkan, C., Chen, Y., … Schlaug, G. (2002). Predictors of hemorrhagic transformation after intravenous recombinant tissue plasminogen activator: Prognostic value of the initial apparent diffusion coefficient and diffusion-weighted lesion volume. Stroke, 33, 2047-2052.

Fink, J. N., Kumara, S., Horkan, C., Linfante, I., Caplan, L. R., & Schlaug, G. (2002). The stroke patient who woke up: Clinical and radiological features, including diffusion and perfusion MRI. Stroke, 33, 988-993.

Selim, M. H., Fink, J. N., Linfante, I., Kumar, S., Schlaug, G., & Caplan, L. R. (2002). Diagnosis of cerebral venous thrombosis with echo-planar T2* - Weighted magnetic resonance imaging. Archives of Neurology, 59, 1021-1026.

Fink, J. N., & McAuley, D. L. (2002). Mastoid air sinus abnormalities associated with lateral venous sinus thrombosis: Cause or consequence? Stroke, 33, 290-292.

Fink, J. N., Kumar, S., Horkan, C., Linfante, I., Selim, M. H., Caplan, L. R., & Schlaug, G. (2002). The stroke patient who woke up: clinical and radiological features, including diffusion and perfusion MRI. Stroke, 33, 988-993.

Fink, J. N., & McAuley, D. L. (2001). Safety of anticoagulation for cerebral venous thrombosis associated with intercerebral hematoma. Neurology, 57, 1138-1139.

Fink, J. N., & McAuley, D. L. (2001). Cerebral venous sinus thrombosis: A diagnostic challenge. Internal Medicine Journal, 31, 384-390.

Fink, J. N., Wallis, W. E., & Haydock, D. A. (2001). Myasthenia gravis with thymoma is more common in the Maori and Pacific Island population of New Zealand. Internal Medicine Journal, 31, 206-210.

Fink, J. N. (2001). Localization of the ″sneeze center″. Neurology, 56, 138.

Fink, J. N. (2001). Localization of the ″sneeze center″ [Letter]. Neurology, 57, 161.

Fink, J. N., Donaldson, I. M., Avery, S. F., & Anderson, T. J. (1998). Is hypokalaemic periodic paralysis more prevalent in Maori? Australian & New Zealand Journal of Medicine, 28, 477-478.

Fink, J. N., Donaldson, I. M., Avery, S. F., & Anderson, T. J. (1998). Is hypokalaemic periodic paralysis more prevalent in Maori? Australian & New Zealand Journal of Medicine, 28(4), 477-478.

Fink, J. N., & Anderson, T. J. (1998). Lower cranial nerve palsies due to carotid artery dissection. New Zealand Medical Journal, 111, 166-168.

Fink, J. N., & Anderson, T. J. (1998). Lower cranial nerve palsies due to carotid artery dissection. New Zealand Medical Journal, 111, 166-168.

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Journal - Research Other

McKinlay, A., Grace, R. C., Dalrymple-Alford, J. C., Anderson, T., Fink, J., & Roger, D. (2008). The accuracy of the Unified Parkinson's Disease Rating Scale (UPDRS-Section 1) as a screening measure for depression [Letter to the editor]. Parkinsonism & Related Disorders, 14(2), 170-172. doi: 10.1016/j.parkreldis.2007.03.002

Jardine, D. L., Hurrell, M. A., & Fink, J. (2007). Tilt-test diagnosis of hypotensive transient ischaemic attacks. Internal Medicine Journal, 37(7), 498-501.

Fink, J. (2006). Ethnic trends in stroke in New Zealand: Closing the gaps or widening? [Editorial]. New Zealand Medical Journal, 119(1245). Retrieved from http://journal.nzma.org.nz/journal/119-1245/2305/content.pdf

Fink, J. N., & Caplan, L. R. (2003). Cerebrovascular cases. Medical Clinics of North America, 87, 755-770.

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