Dr Dhiraj Kumar, Our people, University of Otago, Christchurch, University of Otago, New Zealand

Research Fellow

BSc(Delhi) MTech(Amity) PhD (Ulster)

Email dhiraj.kumar@otago.ac.nz
Tel +64 21 136 6492

Dr Dhiraj Kumar is a chemist with specialisations in physical chemistry and nanobiotechnology.

Research interests

Dhiraj is interested developing engineered nanomaterials for various biomedical applications.

His current research focus in on surface modification of inorganic and organic nanoparticles for ovarian cancer targeting and MARS spectral imaging.

He is involved in various projects with national and international collaborators.

Projects and funding

Functionalised gold nanoparticles for ovarian cancer targeting and MARS spectral CT imaging,

Funded by: Genesis Oncology Trust 2016 and 2017.

A new cancer diagnostics approach – proof of concept

Funded by: Otago collaborative grant (Otago School of Medicine) 2016.

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Publications

Kumar, D., Moghiseh, M., Chitcholtan, K., Mutreja, I., Lowe, C., Kaushik, A., Butler, A., Sykes, P., Anderson, N., & Raja, A. (2023). LHRH conjugated gold nanoparticles assisted efficient ovarian cancer targeting evaluated via spectral photon-counting CT imaging: A proof-of-concept research. Journal of Materials Chemistry B. Advance online publication. doi: 10.1039/d2tb02416k

Alcala-Orozco, C. R., Mutreja, I., Cui, X., Kumar, D., Hooper, G. J., Lim, K. S., & Woodfield, T. B. F. (2020). Design and characterisation of multi-functional strontium-gelatin nanocomposite bioinks with improved print fidelity and osteogenic capacity. Bioprinting, 18, e00073. doi: 10.1016/j.bprint.2019.e00073

Moghiseh, M., Kumar, D., Lewis, J., MARS Collaboration, including Adebileje, S. A., Anderson, N., Asghariomabad, F., Atharifard, A., Bamford, B., Bheesette, S., Butler, A. P. H., Butler, P. H., Dalefield, T., de Ruiter, N. J. A., Gieseg, S. P., Gurney, S., Healy, J. L., Hilton, P. J., Lowe, C., Marfo, E., Panta, R. K., Raja, A. Y., Ramyar, M., Renaud, P., Schleich, N., Searle, E., Sheeja, J. S., … Walsh, M. F. (2018). Cancer imaging with nanoparticles using MARS spectral scanner. Proceedings of the IEEE Nuclear Science Symposium and Medical Imaging Conference. M-16-03. Retrieved from http://www.nssmic.org/2018

Moghiseh, M., Lowe, C., Lewis, J., Kumar, D., Butler, A., Anderson, N., & Raja, A. (2018). Spectral photon-counting molecular imaging for quantification of monoclonal antibody-conjugated gold nanoparticles targeted to lymphoma and breast cancer: An in vitro study. Contrast Media & Molecular Imaging, 2018, 2136840. doi: 10.1155/2018/2136840

Kumar, D., Mutreja, I., Chitcholtan, K., & Sykes, P. (2017). Cytotoxicity and cellular uptake of different sized gold nanoparticles in ovarian cancer cells. Nanotechnology, 28, 475101. doi: 10.1088/1361-6528/aa935e

Journal - Research Article

Kumar, D., Mutreja, I., & Sykes, P. (2016). Seed mediated synthesis of highly mono-dispersed gold nanoparticles in the presence of hydroquinone. Nanotechnology, 27, 355601. doi: 10.1088/0957-4484/27/35/355601

Journal - Research Article

Kumar, D., Mutreja, I., Keshvan, P. C., Bhat, M., Dinda, A. A., & Mitra, S. (2015). Organically modified silica nanoparticles interaction with macrophage cells: Assessment of cell viability on the basis of physicochemical properties. Journal of Pharmaceutical Sciences, 104(11), 3943-3951. doi: 10.1002/jps.24614

Journal - Research Article

Kumar, D., Mutreja, I., Meenan, B. J., & Dixon, D. (2013). The profile of payload release from gold nanoparticles modified with a BODIPY®/PEG mixed monolayer. Journal of Nano Research, 25, 16-30. doi: 10.4028/www.scientific.net/JNanoR.25.16

Journal - Research Article

Mutreja, I., Kumar, D., Boyd, A. R., & Meenan, B. J. (2013). Titania nanotube porosity controls dissolution rate of sputter deposited calcium phosphate (CaP) thin film coatings. RSC Advances, 3, 11263. doi: 10.1039/c3ra40898a

Journal - Research Article

Kumar, D., Meenan, B. J., & Dixon, D. (2012). Glutathione-mediated release of Bodipy^® from PEG cofunctionalized gold nanoparticles. International Journal of Nanomedicine, 7, 4007-4022. doi: 10.2147/IJN.S33726

Journal - Research Article

Kumar, D., Meenan, B. J., Mutreja, I., D'Sa, R., & Dixon, D. (2012). Controlling the size and size distribution of gold nanoparticles: A design of experiment study. International Journal of Nanoscience, 11, 1250023. doi: 10.1142/S0219581X12500238

Journal - Research Article

Manson, J., Kumar, D., Meenan, B. J., & Dixon, D. (2011). Polyethylene glycol functionalized gold nanoparticles: The influence of capping density on stability in various media. Gold Bulletin, 44(2), 99-105. doi: 10.1007/s13404-011-0015-8

Journal - Research Article

Sivasubramaniam, S., Kumar, D., Golovko, V. B., & Alkaisi, M. M. (2013). Current density enhancement in inverted nanopyramid textured crystalline silicon solar cell using gold nanoparticles. Proceedings of SPIE (Vol. 8923): Micro/Nano Materials, Devices, and Systems. 89232F. doi: 10.1117/12.2033731

Conference Contribution - Published proceedings: Full paper

Aw, M. S., Simovic, S., Kumar, D., Addai-Mensah, J., & Losic, D. (2010). The loading and release property of nanoporous anodic alumina for delivery of drugs and drug carriers. Proceedings of the International Conference on Nanoscience and Nanotechnology (ICONN). (pp. 143-1415). IEEE. [Full Paper]

Conference Contribution - Published proceedings: Full paper

Conference Contribution - Published proceedings: Abstract

Raja, A. Y., Moghiesh, M., Kumar, D., Sykes, P., Butler, A. P., & Anderson, N. (2017). Effect of size and concentration of gold nanoparticles on spectral CT imaging of cancer cells. Proceedings of the 8th International Conference on Advanced Materials and Nanotechnology (AMN8). (pp. 105). Retrieved from http://confer.co.nz/amn8/

Conference Contribution - Published proceedings: Abstract

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