Current postgraduate opportunities in pathology and biomedical science

• Radical reactions with superoxide.
• The role of free radicals and chlorine bleach in inflammatory diseases
• Bacterial killing by neutrophils
• The enzymology of peroxidases
• Identification of biomarkers of hypochlorous acid

Professor Tony Kettle

• Infammatory oxidants and cell and tissue injury
• Effects of white cell-derived oxidants on cell signaling responses
• Regulation of transciption factors and gene expression by oxidant stress
• The regulation of neutrophils apoptosis and resolution of inflammation
• The role of vitamin C in the regulation of the hypoxic response - Effect on cancer cell survival
• The hypoxic response and neutrophil apoptosis
• Hypoxia inducible factor-1 and cancer survival after chemotherapy

Professor Margreet Vissers

• Redox regulation of cell signalling
• Cell death pathways in cancer and immune cells
• Mitochondrial dysfunction in ageing and disease
• Understanding mitochondrial antioxidant systems and targeting these pathways in cancer cells
• Anti-cancer and anti-inflammatory properties of isothiocyanates

Professor Mark Hampton

• Pharmacogenomics and genomics
• Genetics of complex traits
• Role of G-quadruplex DNA structures in biological processes

Professor Martin Kennedy

• Gas mediators in inflammation
• Neurogenic inflammation in acute pancreatitis, sepsis, and burns
• Chemokines in acute pancreatitis, sepsis, and burns
• Apoptosis of pancreatic acinar cells

Professor Madhav Bhatia

• Pneumonia and other respiratory infection
• Legionnaires' disease
• Vitamin D and infection
• Staphylococcus aureus disease

• Professor Steve Chambers
• Professor David Murdoch

• Vitamin C in cancer
• Hypoxia, HIF-1 and tumour progression
• Obesity, chemotherapy and breast cancer
• Exercise and breast cancer
• Inflammation and cancer
• Genetic variation and cancer development
• Gene expression and tumour development

• Dr Margaret Currie
• A/Professor Gabi Dachs
• Dr Logan Walker
• Professor Bridget Robinson

• Genetic and acquired abnormalities of blood proteins
• Protein structure, function and disease
• The contribution of post translational changes to disease
• Fibrinogen variation and disease; bleeding, thrombosis, hepatitis and renal failure
• Protein imprinting; novel protein biomarkers of disease; Serum albumin and Apo Al as time resolved markers of pancreatitis

Professor Steve Brennan