Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Allison MillerResearch Technician 

MSc

Email allison.miller@otago.ac.nz
Tel 64 3 378 6268

Research interests

  • Pharmacogenetics
  • Pharmacogenomics

^ Top of page

Publications

Shchepetkina, A. A., Hock, B. D., Miller, A., Kennedy, M. A., & Gieseg, S. P. (2017). Effect of 7,8-dihydroneopterin mediated CD36 down regulation and oxidant scavenging on oxidised low-density lipoprotein induced cell death in human macrophages. International Journal of Biochemistry & Cell Biology, 87, 27-33. doi: 10.1016/j.biocel.2017.03.017

de Jong, L. C., Cree, S., Lattimore, V., Wiggins, G. A. R., Spurdle, A. B., kConFab Investigators, Miller, A., Kennedy, M. A., & Walker, L. C. (2017). Nanopore sequencing of full-length BRCA1 mRNA transcripts reveals co-occurrence of known exon skipping events. Breast Cancer Research, 19, 127. doi: 10.1186/s13058-017-0919-1

Cree, S., Maggo, S., Slow, S., Ton, K., de Jong, L., Anderson, T., Pearson, J., Miller, A., Walker, L., Murdoch, D., & Kennedy, M. (2017). Long read nanopore sequencing in the laboratory. Proceedings of the MapNet Conference. Retrieved from http://scienceevents.co.nz/mapnet/

Kennedy, M. A., Maggo, S. D. S., Foulds, J., Luty, S., Chua, E. W., Cree, S., Ton, K., Liau, Y., Miller, A. L., Chin, P., … Doogue, M. (2017). DNA banking and genetic analysis of adverse drug reactions in the New Zealand healthcare setting. Proceedings of the American Society of Human Genetics (ASHG) Annual Meeting. 2123. Retrieved from http://www.ashg.org/2017meeting/

Liau, Y., Cree, S. M., Maggo, S., Miller, A. L., Pearson, J., & Kennedy, M. A. (2017, September). A nanopore sequencing-based multiplex assay for pharmacogenetics of clopidogrel and warfarin. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Journal - Research Article

Shchepetkina, A. A., Hock, B. D., Miller, A., Kennedy, M. A., & Gieseg, S. P. (2017). Effect of 7,8-dihydroneopterin mediated CD36 down regulation and oxidant scavenging on oxidised low-density lipoprotein induced cell death in human macrophages. International Journal of Biochemistry & Cell Biology, 87, 27-33. doi: 10.1016/j.biocel.2017.03.017

de Jong, L. C., Cree, S., Lattimore, V., Wiggins, G. A. R., Spurdle, A. B., kConFab Investigators, Miller, A., Kennedy, M. A., & Walker, L. C. (2017). Nanopore sequencing of full-length BRCA1 mRNA transcripts reveals co-occurrence of known exon skipping events. Breast Cancer Research, 19, 127. doi: 10.1186/s13058-017-0919-1

Cree, S. L., Fredericks, R., Miller, A., Pearce, F. G., Filichev, V., Fee, C., & Kennedy, M. A. (2016). DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro. FEBS Letters, 590(17), 2870-2883. doi: 10.1002/1873-3468.12331

Jodczyk, S., Pearson, J. F., Aitchison, A., Miller, A. L., Hampton, M. B., & Kennedy, M. A. (2015). Telomere length measurement on the Roche LightCycler 480 platform. Genetic Testing & Molecular Biomarkers, 19(2), 63-68. doi: 10.1089/gtmb.2014.0208

Stevens, A. J., Stuffrein-Roberts, S., Cree, S. L., Gibb, A., Miller, A. L., Doudney, K., Aitchison, A., Eccles, M. R., Joyce, P. R., … Kennedy, M. A. (2014). G-quadruplex structures and CpG methylation cause drop-out of the maternal allele in polymerase chain reaction amplification of the imprinted MEST gene promoter. PLoS ONE, 9(12), e113955. doi: 10.1371/journal.pone.0113955

Chua, E. W., Foulds, J., Miller, A. L., & Kennedy, M. A. (2013). Novel CYP2D6 and CYP2C19 variants identified in a patient with adverse reactions towards venlafaxine monotherapy and dual therapy with nortriptyline and fluoxetine. Pharmacogenetics & Genomics, 23(9), 494-497. doi: 10.1097/FPC.0b013e328363688d

Fergusson, D. M., Boden, J. M., Horwood, L. J., Miller, A., & Kennedy, M. A. (2012). Moderating role of the MAOA genotype in antisocial behaviour. British Journal of Psychiatry, 200(2), 116-123. doi: 10.1192/bjp.bp.111.093328

Fergusson, D. M., Boden, J. M., Horwood, L. J., Miller, A. L., & Kennedy, M. A. (2011). MAOA, abuse exposure and antisocial behaviour: 30-year longitudinal study. British Journal of Psychiatry, 198, 457-463. doi: 10.1192/bjp.bp.110.086991

Fergusson, D. M., Horwood, L. J., Miller, A. L., & Kennedy, M. A. (2011). Life stress, 5-HTTLPR and mental disorder: Findings from a 30-year longitudinal study. British Journal of Psychiatry, 198, 129-135. doi: 10.1192/bjp.bp.110.085993

Doudney, K., Harley, J. A., Pearson, J. F., Miller, A., Aitchison, A., Kennedy, M. A., Porter, R. J., Elmslie, J. L., & Joyce, P. R. (2009). Upstream genetic variant near INSIG2, influences response to carnitine supplementation in bipolar patients with valproate-induced weight gain. Acta Neuropsychiatrica, 21(3), 133-140. doi: 10.1111/j.1601-5215.2009.00379.x

Joyce, P. R., McHugh, P. C., Light, K. J., Rowe, S., Miller, A. L., & Kennedy, M. A. (2009). Relationships between angry-impulsive personality traits and genetic polymorphisms of the dopamine transporter. Biological Psychiatry, 66(8), 717-721. doi: 10.1016/j.biopsych.2009.03.005

Porter, R. J., Mulder, R. T., Joyce, P. R., Miller, A. L., & Kennedy, M. (2008). Tryptophan hydroxylase gene (TPH1) and peripheral tryptophan levels in depression. Journal of Affective Disorders, 109(1-2), 209-212. doi: 10.1016/j.jad.2007.11.010

Roberts, R. L., Gearry, R. B., Hollis-Moffatt, J. E., Miller, A. L., Reid, J., Abkevich, V., … Merriman, T. R., Barclay, M. L., & Kennedy, M. A. (2007). IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease. American Journal of Gastroenterology, 102, 2754-2761.

Light, K. J., Joyce, P. R., Luty, S. E., Mulder, R. T., Carter, J. D., Frampton, C. M. A., Miller, A. L., & Kennedy, M. A. (2007). An association study of DRD2 and COMT polymorphisms with novelty seeking and harm avoidance scores, in two independent samples of depressed patients. Behavioral & Brain Functions, 3(3). Retrieved from http://www.behavioralandbrainfunctions.com/content/3/1/3

Joyce, P. R., McHugh, P. C., McKenzie, J. M., Sullivan, P. F., Mulder, R. T., Luty, S. E., Carter, J. D., Frampton, C. M. A., … Miller, A. L., & Kennedy, M. A. (2006). A dopamine transporter polymorphism is a risk factor for borderline personality disorder in depressed patients. Psychological Medicine, 36, 807-813. doi: 10.1017/s0033291706007288

Joyce, P. R., McKenzie, J. M., Mulder, R. T., Luty, S. E., Sullivan, P. F., Miller, A. L., & Kennedy, M. A. (2006). Genetic, developmental and personality correlates of self-mutilation in depressed patients. Australian & New Zealand Journal of Psychiatry, 40, 225-229.

Light, K. J., Joyce, P. R., Luty, S. E., Mulder, R. T., Frampton, C. M. A., Joyce, L. R. M., Miller, A. L., & Kennedy, M. A. (2006). Preliminary evidence for an association between a dopamine D3 receptor gene variant and obsessive-compulsive personality disorder in patients with major depression. American Journal of Medical Genetics Part B, 141B, 409-413.

Taylor, D. R., Epton, M. J., Kennedy, M. A., Smith, A. D., Iles, S., Miller, A. L., Littlejohn, M. D., Cowan, J. O., Hewitt, T., Swanney, M. P., Brassett, K. P., & Herbison, G. P. (2005). Bronchodilator response in relation to β2-adrenoceptor haplotype in patients with asthma. American Journal of Respiratory & Critical Care Medicine, 172(6), 700-703.

Joyce, P. R., Porter, R. J., Mulder, R. T., Luty, S. E., McKenzie, J. M., Miller, A. L., & Kennedy, M. A. (2005). Reversed diurnal variation in depression: Associations with a differential antidepressant response, tryptophan: Large neutral amino acid ratio and serotonin transporter polymorphisms. Psychological Medicine, 35, 511-517.

Rogers, G., Joyce, P., Mulder, R., Sellman, D., Miller, A., Allington, M., Olds, R., Wells, E., & Kennedy, M. (2004). Association of a duplicated repeat polymorphism in the 5′-untranslated region of the DRD4 gene with novelty seeking. American Journal of Medical Genetics Part B, 126B, 95-98.

Joyce, P. R., Rogers, G. R., Miller, A., Mulder, R. T., Luty, S. E., & Kennedy, M. A. (2003). Polymorphisms of DRD4 and DRD3 and risk of avoidant and obsessive personality traits and disorders. Psychiatry Research, 119, 1-10.

Joyce, P. R., Mulder, R. T., Luty, S. E., McKenzie, J. M., Miller, A., Rogers, G. R., & Kennedy, M. A. (2003). Age-dependent antidepressant pharmacogenomics: Polymorphisms of the serotonin transporter and G protein β3 subunit as predictors of response to fluoxetine and nortriptyline. International Journal of Neuropsychopharmacology, 6, 339-346.

Littlejohn, M. D., Taylor, D. R., Miller, A. L., & Kennedy, M. A. (2002). Determination of β2-adrenergic receptor (ADRB2) haplotypes by a multiplexed polymerase chain reaction assay. Human Mutation, 20(6), 479. doi: 10.1002/humu.9091

Wood, J. G., Joyce, P. R., Miller, A., Mulder, R. T., & Kennedy, M. A. (2002). A polymorphism in the dopamine β-hydroxylase gene is associated with "paranoid ideation" in patients with major depression. Biological Psychiatry, 51, 365-369.

Kennedy, M. A., Rowland, S., Miller, A., Morris, C. M., Neville, L., Dodd, A., … Love, D. R. (1996). Structure and location of the murine adrenoleukodystrophy gene. Genomics, 32(3), 395-400.

^ Top of page

Journal - Research Other

Bridgman, P. G., Finsterer, J., Lacey, C., Kimber, B., Parkin, P. J., Miller, A. L., & Kennedy, M. A. (2016). CTG-repeat expansions in the DMPK gene do not cause takotsubo syndrome [Short communication]. International Journal of Cardiology, 203, 107-108. doi: 10.1016/j.ijcard.2015.10.112

Chua, E.-W., Miller, A. L., & Kennedy, M. A. (2015). Choice of PCR microtube can impact on the success of long-range PCRs. Analytical Biochemistry, 477, 115-117. doi: 10.1016/j.ab.2015.02.023

Pearson, J. F., Fergusson, D. M., Horwood, L. J., Miller, A. L., Sullivan, P. F., Youfang, L. E., & Kennedy, M. A. (2013). Increased risk of major depression by childhood abuse is not modified by CNR1 genotype. American Journal of Medical Genetics Part B, 162(2), 224-226. doi: 10.1002/ajmg.b.32124

Light, K. J., Miller, A. L., Doughty, C. J., Joyce, P. R., Olds, R. J., & Kennedy, M. A. (2007). FAT and bipolar affective disorder [Letter to the editor]. Molecular Psychiatry, 12, 899-900.

^ Top of page

Conference Contribution - Published proceedings: Abstract

Cree, S., Maggo, S., Slow, S., Ton, K., de Jong, L., Anderson, T., Pearson, J., Miller, A., Walker, L., Murdoch, D., & Kennedy, M. (2017). Long read nanopore sequencing in the laboratory. Proceedings of the MapNet Conference. Retrieved from http://scienceevents.co.nz/mapnet/

Kennedy, M. A., Maggo, S. D. S., Foulds, J., Luty, S., Chua, E. W., Cree, S., Ton, K., Liau, Y., Miller, A. L., Chin, P., … Doogue, M. (2017). DNA banking and genetic analysis of adverse drug reactions in the New Zealand healthcare setting. Proceedings of the American Society of Human Genetics (ASHG) Annual Meeting. 2123. Retrieved from http://www.ashg.org/2017meeting/

Stevens, A. J., Stuffrein-Roberts, S., Macmil, S., Gibb, A., Doudney, K., Miller, A. L., Bagshaw, A., Aitchison, A., Eccles, M. R., Joyce, P. R., … Kennedy, M. A. (2013). Allelic-dropout during PCR of the imprinted MEST promoter caused by interaction between G-quadruplex structures and DNA methylation. Proceedings of the 4th International Meeting on G-quadruplex Nucleic Acids: From Structure to Chemistry and Biology. 83. Retrieved from http://www.g4meeting2013.com/

Macmil, S. L., Fredericks, R., Miller, A., Fee, C., Filichev, V. V., & Kennedy, M. A. (2013). Structure based function: Investigating the role of G-quadruplex structures in de novo DNA methylation. Proceedings of the 4th International Meeting on G-quadruplex Nucleic Acids: From Structure to Chemistry and Biology. 79. Retrieved from http://www.g4meeting2013.com/

Flanagan, L., Sykes, P., Miller, A., & Hibma, M. (2011). Antigen presenting cells in the human papillomavirus-induced tumour microenvironment. New Zealand Medical Journal, 124(1346). Retrieved from http://journal.nzma.org.nz/journal/124-1346/4980/content.pdf

Kennedy, M. A., Boden, J. M., Miller, A., Horwood, L. J., & Fergusson, D. M. (2008). Is the CHRNA3-CHRNA5 genomic region really a susceptibility locus for nicotine addiction? Proceedings of the 4th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm

Kennedy, M. A., Bland, M. V., Roberts, R. L., McHugh, P. C., Light, K. J., Miller, A. L., & Joyce, P. R. (2008). The GATA2 transcription factor gene: Promotor haplotypes and preliminary association with neuropsychiatric phenotypes. Proceedings of the American Society of Human Genetics 58th Annual Meeting. (pp. 362). ASHG. Retrieved from http://www.ashg.org/2008meeting/pdf/abstractbook1.pdf

Roberts, R. L., Gearry, R. B., Hollis-Moffatt, J. E., Miller, A. L., Reid, J., Abkevich, V., … Merriman, T. R., Barclay, M. L., & Kennedy, M. A. (2007). IL23R R381Q & ATG16L1 T300A are associated with Crohn's disease in a population-based Caucasian cohort. Journal of Gastroenterology & Hepatology, 22(Suppl. 3), (pp. A305). doi: 10.1111/j.1440-1746.2007.05172.x

Roberts, R. L., Gearry, R. B., Hollis-Moffatt, J. E., Miller, A. L., Reid, J., Abkevich, V., … Merriman, T. R., Barclay, M. L., & Kennedy, M. A. (2007). IL23R R381Q & ATG16L1 T300A are associated with Crohn's disease in a population-based New Zealand Caucasian cohort. Gut. 56(Suppl. III), (pp. A19). [Abstract]

Roberts, R. L., Gearry, R. B., Hollis-Moffatt, J. E., Miller, A. L., Reid, J., Abkevich, V., … Merriman, T. R., Barclay, M. L., & Kennedy, M. A. (2007). IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease. New Zealand Medical Journal, 120(1266). Retrieved from http://journal.nzma.org.nz/journal/120-1266/2848/content.pdf

Rogers, G. R., Miller, A., Damak, S., & Kennedy, M. A. (2000). A mouse model of adrenoleukodystrophy: Analysis of cytokine gene expression in the brain. An oral presentation. Bulletin of the Human Genetics Society of Australasia. 13(2). NSW, Australia: SHS, Northwest Business Park. [Abstract]

^ Top of page

Conference Contribution - Poster Presentation (not in published proceedings)

Stevens, A., Stuffrein-Roberts, S., Miller, A., Gibb, A., Doudney, K., Bagshaw, A., Aitchison, A., Eccles, M., … Kennedy, M. (2012, August). G-quadruplex DNA structures, genomic imprinting and allelic drop-out in PCR. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Jodczyk, S., Miller, A., Fergusson, D., Horwood, J., & Kennedy, M. (2012, March). Association between nicotine and alcohol dependence and short mean telomere length in a longitudinal birth cohort study. Poster session presented at the Human Genome Meeting (HUGO): Genetics and Genomics in Personalised Medicine, Sydney, Australia.

^ Top of page

Conference Contribution - Verbal presentation and other Conference outputs

Liau, Y., Cree, S. M., Maggo, S., Miller, A. L., Pearson, J., & Kennedy, M. A. (2017, September). A nanopore sequencing-based multiplex assay for pharmacogenetics of clopidogrel and warfarin. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Kennedy, M. A., Cree, S. L., Miller, A. L., Pearson, J., Maggo, S., Liau, Y., Ton, K., de Jong, L., & Walker, L. C. (2017, September). The MinION nanopore sequencer: Toy or tool? Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Cree, S. L., Miller, A. L., Chua, E. W., Maggo, S., & Kennedy, M. A. (2015, August). Long-read nanopore Sequencing for the detection of genetic polymorphisms in the CYP2D6 gene. Verbal presentation at the 7th Annual New Zealand Next Generation Sequencing (NGS) Conference, Palmerston North, New Zealand.

Maggo, S. D. S., Foulds, J., Luty, S. E., Miller, A. L., Kennedy, H., Doogue, M., & Kennedy, M. A. (2015, September). Understanding adverse drug reactions using genome sequencing (UDRUGS): Recent cases on SSRIs and SNRIs. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand.

Kennedy, M., Doudney, K., Bickley, V., Bridgman, P., Cameron, V., Cadzow, M., Black, M., Merriman, T., … Miller, A., Zarifeh, J., Kimber, B., George, P., & Lacey, C. (2015, August-September). Genomes, earthquakes and broken hearts. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Kennedy, M. A., Chua, E. W., Macmil, S., Foulds, J., Barclay, M., Savage, R., … Miller, A. (2013, August). Genomic medicine and adverse drug reactions. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Chua, E. W., Macmil, S., Foulds, J., Barclay, M., Savage, R., Helsby, N. A., Miller, A., & Kennedy, M. A. (2013, August). Understanding adverse Drug Reactions or responses Using Genomic Sequencing (UDRUGS). Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Section (ASCEPT-NZ) Annual Scientific Meeting, Queenstown, New Zealand.

Chua, E. W., Foulds, J., Miller, A. L., & Kennedy, M. A. (2012, November). Novel CYP2D6 mutation in a patient with poor response to venlafaxine. Verbal presentation at the 8th Annual Carney Pharmacogenomics Symposium, Christchurch, New Zealand.

More publications...