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Emma Spencer Assistant Research Fellow

BBiomedSc(Hons) PhD (Otago)

Email emma.spencer@otago.ac.nz
Tel +64 3 364 1648

Research interests

Dr Emma Spencer is involved in clinical studies investigating the bioavailability and potential health effects of vitamin C.

Health Research Open Day Lecture

Watch Dr Spencer's short presentation from the UOC Health Research Open Day in September 2016 on her PhD research which targeted cancer cells with compounds from nature.

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Publications

Spencer, E. S., O'Connor, K. M., & Hampton, M. B. (2017). Isothiocyanates trigger early disruption of mitochondrial function in cells overexpressing Bcl-2. Free Radical Biology & Medicine, 108(Suppl. 1), (pp. S51). doi: 10.1016/j.freeradbiomed.2017.04.185

Spencer, E. S. (2017). Exploring the anti-cancer and anti-inflammatory properties of isothiocyanates (PhD). University of Otago, Dunedin, New Zealand. Retrieved from http://hdl.handle.net/10523/7254

Spencer, E. S., Dale, E. J., Gommans, A. L., Rutledge, M. T., Vo, C. T., Nakatani, Y., Gamble, A. B., Smith, R. A. J., Wilbanks, S. M., Hampton, M. B., & Tyndall, J. D. A. (2015). Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor. European Journal of Medicinal Chemistry, 93, 501-510. doi: 10.1016/j.ejmech.2015.02.012

Spencer, E., Dickerhof, N., Tyndall, J., Bernhagen, J., Kettle, A., & Hampton, M. (2015). Assessing inhibition of macrophage migration inhibitory factor by isothiocyanates. Free Radical Biology & Medicine, 86(Suppl. 1), (pp. S42-S43). doi: 10.1016/j.freeradbiomed.2015.07.145

Shaw, I. C., Spencer, E., Lambert, T., Holzenkaempfer, M., Gaw, S., & Stringer, M. (2014). Measurement of kidney cadmium in embalmed New Zealand cadavers. New Zealand Medical Journal, 127(1392). Retrieved from http://www.nzma.org.nz/journal

Journal - Research Article

Spencer, E. S., Dale, E. J., Gommans, A. L., Rutledge, M. T., Vo, C. T., Nakatani, Y., Gamble, A. B., Smith, R. A. J., Wilbanks, S. M., Hampton, M. B., & Tyndall, J. D. A. (2015). Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor. European Journal of Medicinal Chemistry, 93, 501-510. doi: 10.1016/j.ejmech.2015.02.012

Shaw, I. C., Spencer, E., Lambert, T., Holzenkaempfer, M., Gaw, S., & Stringer, M. (2014). Measurement of kidney cadmium in embalmed New Zealand cadavers. New Zealand Medical Journal, 127(1392). Retrieved from http://www.nzma.org.nz/journal

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Conference Contribution - Published proceedings: Abstract

Spencer, E. S., O'Connor, K. M., & Hampton, M. B. (2017). Isothiocyanates trigger early disruption of mitochondrial function in cells overexpressing Bcl-2. Free Radical Biology & Medicine, 108(Suppl. 1), (pp. S51). doi: 10.1016/j.freeradbiomed.2017.04.185

Spencer, E., Dickerhof, N., Tyndall, J., Bernhagen, J., Kettle, A., & Hampton, M. (2015). Assessing inhibition of macrophage migration inhibitory factor by isothiocyanates. Free Radical Biology & Medicine, 86(Suppl. 1), (pp. S42-S43). doi: 10.1016/j.freeradbiomed.2015.07.145

Tyndall, J. D. A., Spencer, E. S., Dale, E. J., Gommans, A. L., Rutledge, M. T., Vo, C. T., Nakatani, Y., Gamble, A. B., Smith, R. A. J., Wilbanks, S. M., & Hampton, M. B. (2014). Multiple binding modes of isothiocyanate inhibitors of macrophage migration inhibitory factor define structure activity relationships. Proceedings of the CRYSTAL29: 29th Biennial Conference of the Society of Crystallographers in Australia and New Zealand (SCANZ). (pp. 88). Retrieved from http://www.crystal29.com/

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Conference Contribution - Poster Presentation (not in published proceedings)

Tyndall, J. D. A., Spencer, E. S., Dale, E. J., Gommans, A. L., Rutledge, M. T., Vo, C. T., Nakatani, Y., Gamble, A. B., Smith, R. A. J., Wilbanks, S. M., & Hampton, M. B. (2014, August). Multiple binding modes of isothiocyanate inhibitors of macrophage migration inhibitory factor define design strategies. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Spencer, E. S., Dale, E., Smith, R. A. J., Gamble, A. B., Tyndall, J. D. A., Rutledge, M. T., Wilbanks, S. M., Dickerhof, N., Kettle, A. J., & Hampton, M. B. (2013, August). Assessing inhibition of macrophage migration inhibitory factor by novel isothiocyanates. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

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Conference Contribution - Verbal presentation and other Conference outputs

Tyndall, J. D. A., Dale, E. J., Spencer, E. S., Falvey, J. D., Smith, R. A. J., & Hampton, M. B. (2011, November-December). Isothiocyanate inhibitors of the proinflammatory cytokine macrophage migration inhibitory factor. Verbal presentation at the New Zealand Institute of Chemistry (NZIC) Conference, Hamilton, New Zealand.

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Awarded Doctoral Degree

Spencer, E. S. (2017). Exploring the anti-cancer and anti-inflammatory properties of isothiocyanates (PhD). University of Otago, Dunedin, New Zealand. Retrieved from http://hdl.handle.net/10523/7254

More publications...