PhD CandidateResearch Interests
George Wiggins is investigating gene expression variability in breast tumour development.
His PhD supervisors are Dr Logan Walker, Dr John Pearson, Associate Professor Mik Black and Dr Anita Dunbier
Publications
Wiggins, G., Pearson, J., Black, M., Dunbier, A., & Walker, L. (2018). Expression variability is associated with breast tumour subtype. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/
Walker, L. C., Pearson, J. F., Wiggins, G. A. R., Giles, G. G., Hopper, J. L., & Southey, M. C. (2017). Increased genomic burden of germline copy number variants is associated with early onset breast cancer: Australian breast cancer family registry. Breast Cancer Research, 19, 30. doi: 10.1186/s13058-017-0825-6
Walker, L. C., Marquart, L., Pearson, J. F., Wiggins, G. A. R., O'Mara, T. A., Parsons, M. T., … Spurdle, A. B. (2017). Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers. European Journal of Human Genetics, 25, 432-438. doi: 10.1038/ejhg.2016.203
de Jong, L. C., Cree, S., Lattimore, V., Wiggins, G. A. R., Spurdle, A. B., kConFab Investigators, Miller, A., Kennedy, M. A., & Walker, L. C. (2017). Nanopore sequencing of full-length BRCA1 mRNA transcripts reveals co-occurrence of known exon skipping events. Breast Cancer Research, 19, 127. doi: 10.1186/s13058-017-0919-1
Pearson, J. F., Wiggins, G. A. R., Black, M., Dunbier, A., & Walker, L. C. (2017). Expression variability is associated with breast cancer tumour subtype. Proceedings of the American Society of Human Genetics (ASHG) Annual Meeting. 746. Retrieved from http://www.ashg.org/2017meeting/
Journal - Research Article
Walker, L. C., Pearson, J. F., Wiggins, G. A. R., Giles, G. G., Hopper, J. L., & Southey, M. C. (2017). Increased genomic burden of germline copy number variants is associated with early onset breast cancer: Australian breast cancer family registry. Breast Cancer Research, 19, 30. doi: 10.1186/s13058-017-0825-6
de Jong, L. C., Cree, S., Lattimore, V., Wiggins, G. A. R., Spurdle, A. B., kConFab Investigators, Miller, A., Kennedy, M. A., & Walker, L. C. (2017). Nanopore sequencing of full-length BRCA1 mRNA transcripts reveals co-occurrence of known exon skipping events. Breast Cancer Research, 19, 127. doi: 10.1186/s13058-017-0919-1
Walker, L. C., Marquart, L., Pearson, J. F., Wiggins, G. A. R., O'Mara, T. A., Parsons, M. T., … Spurdle, A. B. (2017). Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers. European Journal of Human Genetics, 25, 432-438. doi: 10.1038/ejhg.2016.203
Wiggins, G., & Legge, M. (2016). Cyclic variation of cellular clock proteins in the mouse estrous ovary. Journal of Reproduction & Infertility, 17(4), 192-198.
Walker, L. C., Wiggins, G. A. R., & Pearson, J. F. (2015). The role of constitutional copy number variants in breast cancer. Microarrays, 4(3), 407-423. doi: 10.3390/microarrays4030407
Chen, A., Beetham, H., Black, M. A., Priya, R., Telford, B. J., Guest, J., Wiggins, G. A. R., Godwin, T. D., … Guilford, P. J. (2014). E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition. BMC Cancer, 14, 552. doi: 10.1186/1471-2407-14-552
Willson, J. S. B., Godwin, T. D., Wiggins, G. A. R., Guilford, P. J., & McCall, J. L. (2013). Primary hepatocellular neoplasms in a MODY3 family with a novel HNF1A germline mutation. Journal of Hepatology, 59(4), 904-907. doi: 10.1016/j.jhep.2013.05.024
Conference Contribution - Published proceedings: Abstract
Wiggins, G., Pearson, J., Black, M., Dunbier, A., & Walker, L. (2018). Expression variability is associated with breast tumour subtype. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/
Pearson, J. F., Wiggins, G. A. R., Black, M., Dunbier, A., & Walker, L. C. (2017). Expression variability is associated with breast cancer tumour subtype. Proceedings of the American Society of Human Genetics (ASHG) Annual Meeting. 746. Retrieved from http://www.ashg.org/2017meeting/
Conference Contribution - Poster Presentation (not in published proceedings)
Wiggins, G., & Legge, M. (2011, September). Investigation of a molecular clock in mouse ovaries. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Wiggins, G. A. R., Pearson, J., Dunbier, A., Black, M., & Walker, L. (2016, August-September). Gene expression variability in breast tumours. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
